He discovered several angiostatic proteins for potential treatment of cancer. Cao's laboratory discovered catechins in green ...
When mutations occur in the rhodopsin the directional protein movement is affected because the mutations can affect protein ... Many angiostatic factors have been shown to counteract the effect of increasing local VEGF. The naturally occurring form of ... The protein RPE65 is used in the retinoid cycle where the all-trans-retinol within the rod outer segment is isomerized to its ... The opsin proteins are made in the photoreceptor inner segments, then transported to the outer segment, and eventually ...
... matrix protein (M), fusion protein (F), neuraminidase (NA) and large protein (L). All these proteins have variable functions ... regulation of cell growth and mediation of angiostatic effects. Human mast cell infection with SeV induces expression of ... F-protein, as other paramyxoviral fusion proteins, is a trimeric class I viral membrane fusion protein. It is produced in the ... "ASGR1 protein expression summary - The Human Protein Atlas". www.proteinatlas.org. Retrieved 2020-01-14. "ASGR2 protein ...
... angiostatic proteins MeSH D12.644.276.100.450.500 - angiostatins MeSH D12.644.276.100.450.750 - endostatins MeSH D12.644. ... 14-3-3 proteins MeSH D12.644.360.024.318 - proto-oncogene proteins c-crk MeSH D12.644.360.024.326 - proto-oncogene proteins c- ... ral gtp-binding proteins MeSH D12.644.360.525.462 - ran gtp-binding protein MeSH D12.644.360.525.475 - rap gtp-binding proteins ... wnt proteins MeSH D12.644.276.996.500 - wnt1 protein MeSH D12.644.276.996.750 - wnt2 protein MeSH D12.644.360.011 - activating ...
... angiostatic proteins MeSH D23.348.479.311.200.500 - angiostatins MeSH D23.348.479.311.200.750 - endostatins MeSH D23.348. ... hiv core protein p24 MeSH D23.050.327.520.330 - hiv envelope protein gp41 MeSH D23.050.327.520.350 - hiv envelope protein gp120 ... adenovirus e1 proteins MeSH D23.050.327.045.060 - adenovirus e2 proteins MeSH D23.050.327.045.070 - adenovirus e3 proteins MeSH ... ldl-receptor related protein 2 MeSH D23.050.422.500.750 - ldl-receptor related protein-associated protein MeSH D23.050.550.325 ...
The regulatory roles and implications of these proteins in human diseases have been largely overlooked for decades. His series ... "A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase". Nature Structural & ... Center for Medicinal Protein Network and Systems Biology 2010-Present Director, Medicinal Bioconvergence Research Center 2000 ... "Downregulation of FUSE-binding protein and c-myc by tRNA synthetase cofactor p38 is required for lung cell differentiation". ...
May 2011). "Enhancement of T-cell-mediated antitumor response: angiostatic adjuvant to immunotherapy against cancer". Clinical ... and proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate ...
They may use a similar "protein-adduction" mechanism; if so the target protein(s) for these effects have not been defined or ... Angiostatic effect of 15(S)-HPETE involves induction of apoptosis in adipose endothelial cells". PeerJ. 2: e635. doi:10.7717/ ... 15-hydroxyeicosatetraenoic acid promotes hepatocellular cancer cells growth through protein kinase B and heat shock protein 90 ... Wang, Y; Liang, D; Wang, S; Qiu, Z; Chu, X; Chen, S; Li, L; Nie, X; Zhang, R; Wang, Z; Zhu, D (2010). "Role of the G-protein ...
The HSPG2 gene codes for a 4,391 amino acid protein with a molecular weight of 468,829. It is one of the largest known proteins ... the angiostatic C-terminal fragment of perlecan". J. Biol. Chem. 280 (8): 7080-7. doi:10.1074/jbc.M409841200. PMID 15591058. ... This is not evidence that MMP-2 and MMP-9 directly cleave perlecan protein in vivo but shows that the proteins clearly modulate ... "Fibroblast growth factor-binding protein is a novel partner for perlecan protein core". J. Biol. Chem. 276 (13): 10263-71. doi: ...
Vascular endothelial growth factor (VEGF) is a type of protein the body cells produce to stimulate the growth of new blood ... angiostatic), or lower the permeability of blood vessels (anti-permeability), in turn curing various eye diseases. Disorders/ ... It is shown to be able to significantly decrease intercellular adhesion molecule-1 mRNA and protein levels and therefore reduce ...