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*  Congenital dyserythropoietic anemia
... type I-is defined by moderate to severe macrocytic anemia (commonly in neonates as ... Congenital dyserythropoietic anemia type IV- is defined by having severe anemia at birth (type V and VI are recognized). ... Congenital dyserythropoietic anemia type III- is defined by mild anemia and retinal degeneration. ... "Orphanet: Congenital dyserythropoietic anemia". www.orpha.net. Retrieved 2 January 2018. "Congenital dyserythropoietic anemia ...
*  Macrocytic anemia
The term macrocytic is from Greek words meaning "large cell". A macrocytic class of anemia is an anemia (defined as blood with ... In contrast, in microcytic anemia, the erythrocytes are smaller than normal. In a macrocytic anemia, the larger red cells are ... Especially common causes of macrocytic anemias are the so-called megaloblastic anemias,[citation needed] in which cells are ... anemia). Macrocytic anemia is not a disease in the sense of having a single pathology but, rather, is a condition. As such, it ...
*  Macrocytosis
Macrocytic anemia Greenberg, P. L., et al. "Myelodysplastic syndromes: clinical practice guidelines in oncology." Journal of ... liver disease myeloproliferative disease myelodysplastic syndrome which most commonly presents with macrocytic anemia chronic ... hypothyroidism chronic obstructive airway disease aplastic anemia reticulocytosis (commonly from hemolysis or a recent history ...
*  Hans Grüneberg
Grüneberg, H. (1939). "Inherited Macrocytic Anemias in the House Mouse". Genetics. 24 (6): 777-810. PMC 1209073 . PMID 17246952 ...
*  Lesch-Nyhan syndrome
Some may also be afflicted with macrocytic anemia. Virtually all patients are male; males suffer delayed growth and puberty, ... Because a lack of HGPRT causes the body to poorly utilize vitamin B12, some boys may develop megaloblastic anemia. LNS is an X- ...
*  List of OMIM disorder codes
PTEN Macrocytic anemia, refractory, due to 5q deletion, somatic; 153550; RPS14 Macrothrombocytopenia and progressive ... SCN5A Heinz body anemia; 140700; HBA2 Heinz body anemias, alpha-; 140700; HBA1 Heinz body anemias, beta-; 140700; HBB HELLP ... RPL5 Diamond-Blackfan anemia 7; 612562; RPL11 Diamond-Blackfan anemia 8; 612563; RPS7 Diamond-Blackfan anemia 9; 613308; RPS10 ... KCNJ11 Diamond-Blackfan anemia 1; 105650; RPS19 Diamond-Blackfan anemia 10; 613309; RPS26 Diamond-Blackfan anemia 4; 612527; ...
*  Lucy Wills
Lancet 229 311-14 Wills, L & Evans, BDF (1938), Tropical macrocytic anaemia: its relation to pernicious anaemia. Lancet 232 416 ... This anaemia was then known as 'pernicious anaemia of pregnancy'. However, Lucy Wills was able to demonstrate that the anaemia ... pernicious anaemia' of pregnancy. Part IV The production of pernicious anaemia (Bartonella anaemia) in intact albino rats by ... Macrocytic anaemia is characterised by enlarged red blood cells and is life-threatening. Poor pregnant women in the tropics ...
*  Folate deficiency
In adults, anemia (macrocytic, megaloblastic anemia) can be a sign of advanced folate deficiency. Women with folate deficiency ... Anemia is a late finding in folate deficiency and folate deficiency anemia is the term given for this medical condition. It is ... to avoid macrocytic anemia caused by folate deficiency. Folate is often also supplemented before some high dose chemotherapy ... megaloblastic anemia, neurological deterioration. Microcephaly, irritability, developmental delay, seizures, blindness and ...
*  2-Methoxyethanol
Workers exposed to high levels are at risk for granulocytopenia, macrocytic anemia, oligospermia, and azoospermia. The ...
*  Anemia
... "megaloblastic anemia" or "nonmegaloblastic macrocytic anemia". The cause of megaloblastic anemia is primarily a failure of DNA ... If the cells are small, it is microcytic anemia. If they are large, it is macrocytic anemia while if they are normal sized, it ... Fanconi anemia is a hereditary disorder or defect featuring aplastic anemia and various other abnormalities. Anemia of renal ... Hyperanemia is a severe form of anemia, in which the hematocrit is below 10%. Refractory anemia, an anemia which does not ...
*  Proton-coupled folate transporter
Severe anemia, usually macrocytic, always accompanies the folate deficiency. Sometimes there is pancytopenia and/or ... by the observation that humans or mice with loss-of-function PCFT mutations are not iron or heme deficient and the anemia, and ...
*  Mean corpuscular volume
... normocytic anemia (MCV within normal range) or macrocytic anemia (MCV above normal range). Normocytic anemia is usually deemed ... sideroblastic anemia or chronic disease. In iron deficiency anemia (microcytic anemia), it can be as low as 60 to 70 ... In pernicious anemia (macrocytic), MCV can range up to 150 femtolitres. An elevated MCV is also associated with alcoholism (as ... In patients with anemia, it is the MCV measurement that allows classification as either a microcytic anemia (MCV below normal ...
*  Glossitis
Folate deficiency (vitamin B9 deficiency) can cause glossitis, along with macrocytic anemia, thrombocytopenia, leukopenia, ... Apart from pernicious anemia discussed above, any other cause of vitamin B12 deficiency can cause glossitis, which tends to be ... Anemia and nutritional deficiencies (such as a deficiency in niacin, riboflavin, iron, or Vitamin E) must be treated, often by ... Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage. This ...
*  Cubam
... and subsequent macrocytic anemia. The most common cause of Vitamin B12 deficiency is deficiency of the intrinsic factor (IF) ... This can lead to pernicious anemia. However, a rare abnormality of AMN can also cause vitamin B12 anemia; this condition is ... which manifests as macrocytic, megaloblastic anemia. Severe vitamin B12 deficiency is most commonly caused by an autoimmune ...
*  Food fortification
Diseases associated with folic acid deficiency include: megaloblastic or macrocytic anemia, cardiovascular disease, certain ... of high folate levels and low vitamin B-12 status may be associated with an increased risk of cognitive impairment and anemia ...
*  Vitamin B12 deficiency anemia
... macrocytic anemia) and a normal MCHC (normochromic anemia). Ovalocytes are also typically seen on the blood smear, and a ... Vitamin B12 deficiency anemia, of which pernicious anemia is a type, is a disease in which not enough red blood cells are ... Many of the signs and symptoms are due to anemia itself, when anemia is present. Symptoms may consist of the triad of tingling ... not pernicious anemia). Whipple discovered ingesting large amounts of liver seemed to cure anemia from blood loss, and tried ...
*  MTRR (gene)
Additionally, macrocytic anemia is a typical feature of the CblE defect and can be corrected though OH-Cobalamin administration ... Known as the Iberian mutation, prevalent in homocystinuria megaloblastic anemia due to impaired cobalamin metabolism. Mainly ... Symptoms of this condition comprise developmental retardation, megaloblastic anemia, homocystinuria, hypomethioninemia, ... megaloblastic anemia, Alzheimer's diseases and cognitive dysfunction in the elderly. Presence of the mutant variant (66A>G) is ...
*  Subacute combined degeneration of spinal cord
... looking for megaloblastic anemia if there is also folic acid deficiency or macrocytic anemia. The Schilling Test is no longer ... It is usually associated with pernicious anemia. The onset is gradual and uniform. The pathological findings of subacute ...
*  Hereditary folate malabsorption
... present within a few months after birth with failure to thrive and severe folate deficiency manifested as macrocytic anemia and ... This will rapidly correct the anemia, immune deficiency and GI signs. The challenge is to achieve adequate treatment of the ...
*  Congenital dyserythropoietic anemia type III
... (CDA III) is a rare autosomal dominant disorder characterized by macrocytic anemia ... Anemia Type III Congenital dyserythropoietic anemia at the US National Institutes of Health Home Genetic Reference Rare Anemias ... Congenital dyserythropoietic anemia Thalassemia Hemoglobinopathy List of hematologic conditions Localization of the gene for ... congenital dyserythropoietic anemia type III, CDAN3, to chromosome 15q21-q25 congenital dyserythropoietic anemia - Genetic Home ...
*  Chromosome 5q deletion syndrome
The 5q-syndrome is characterized by macrocytic anemia, often a moderate thrombocytosis, erythroblastopenia, megakaryocyte ... Lenalidomide has activity in 5q- syndrome and is FDA approved for red blood cell (RBC) transfusion-dependent anemia due to low ... Haploinsufficiency of RPS14 plays a central role, and contributes to the anemia via both p53-dependent and p53-independent ... This syndrome affects bone marrow cells causing treatment-resistant anemia and myelodysplastic syndromes that may lead to acute ...
*  Imerslund-Gräsbeck syndrome
Defined as those seen in any macrocytic, megaloblastic anemia:[citation needed] Anemia: causing fatigue, conjuctival pallor, ... and this is in fact a great way to distinguish folate deficiency macrocytic anemia, from vitamin B12 anemia. The following is ... Laboratory findings indicating increased MCV (Mean Corpuscular Volume), decreased Hgb/Hct (indicating anemia), and decreased ... anemia. Vitamin B12 however has two major forms in the human body: Deoxyadenosyl B12 or as it is sometimes referred to Ado B12 ...
*  Diamond-Blackfan anemia
... is characterized by normocytic or macrocytic anemia (low red blood cell counts) with decreased ... UK Diamond Blackfan Anaemia Charity Diamond Blackfan Anæmia International Support Group Diamond Blackfan Anemia Registry of ... GeneReviews/NCBI/NIH/UW entry on Diamond-Blackfan Anemia OMIM entries on Diamond-Blackfan Anemia Diamond-Blackfan Anemia ... Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents in infancy. DBA causes low red blood cell ...
*  Animal source foods
... anemias (iron deficiency anemia and macrocytic anemia), rickets, night blindness, impaired cognitive functioning, neuromuscular ...
*  Haptocorrin
Vitamin B12 is an essential water-soluble vitamin, the deficiency of which creates anemia (macrocytic anemia), decreased bone ... marrow cell production (anemia, pancytopenia), neurological problems, as well as metabolic issues (methylmalonyl-CoA acidosis ...
*  Normocytic anemia
... deficiency or a mixture of conditions producing microcytic and macrocytic anemia. Blood loss, suppressed production of RBCs or ... Normocytic anemia is a type of anemia and is a common issue that occurs for men and women typically over 85 years old. Its ... A normocytic anemia is defined as an anemia with a mean corpuscular volume (MCV) of 80-100 which is the normal range. However, ... anemia of chronic disease, aplastic anemia); an increased production of HbS as seen in sickle cell disease (not sickle cell ...
*  William P. Murphy
... in 1934 with George Richards Minot and George Hoyt Whipple for their combined work in devising and treating macrocytic anemia ( ... He discovered that ingesting large amounts of liver seemed to restore anemia more quickly of all foods. Minot and Whipple then ... These investigations showed that iron in the liver was responsible for curing anemia from bleeding, but meanwhile liver had ... specifically, pernicious anemia). Murphy was born on February 6, 1892, at Stoughton, Wisconsin. He was educated at the public ...