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*  Neomycin
Aminoglycosides such as neomycin are known for their ability to bind to duplex RNA with high affinity. The association constant ... Neomycin is an aminoglycoside antibiotic found in many topical medications such as creams, ointments, and eyedrops. The ... Neomycin belongs to aminoglycoside class of antibiotics that contain two or more aminosugars connected by glycosidic bonds. ... Similar to other aminoglycosides, neomycin has excellent activity against Gram-negative bacteria, and is partially effective ...
*  Sisomicin
... is the most predictably active aminoglycoside against gram-positive bacteria. Like most other aminoglycosides, ... Sisomicin (bactoCeaze or Ensamycin) is an aminoglycoside antibiotic, isolated from the fermentation broth of a new species of ... Mar 1978). "The mechanisms of resistance to aminoglycosides in the genus Pseudomonas". J Antimicrob Chemother. 4 (2): 121-129. ... Jun 1974). "In vitro comparison of four aminoglycoside antibiotics: sisomicin, gentamicin, tobramycin, and BB-K8". Antimicrob. ...
*  Tobramycin
Aminoglycoside-induced ototoxicity is generally irreversible. As with all amino glycosides, tobramycin is also nephrotoxic, it ... Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given ... Like other aminoglycosides, tobramycin is ototoxic: it can cause hearing loss, or a loss of equilibrioception, or both in ... Tobramycin is an aminoglycoside antibiotic derived from Streptomyces tenebrarius and used to treat various types of bacterial ...
*  Aminoglycoside
The aminoglycoside gentamicin has been used to treat cystic fibrosis (CF) cells in the laboratory to induce them to grow full- ... Aminoglycosides are in pregnancy category D, that is, there is positive evidence of human fetal risk based on adverse reaction ... This revived interest in the use of aminoglycosides has brought back to light the debate on the two major issues related to ... Aminoglycosides can exacerbate weakness in patients with myasthenia gravis, and use is therefore avoided in these patients. ...
*  Aminoglycoside N6'-acetyltransferase
Other names in common use include aminoglycoside 6'-N-acetyltransferase, aminoglycoside-6'-acetyltransferase, aminoglycoside-6- ... In enzymology, an aminoglycoside N6'-acetyltransferase (EC 2.3.1.82) is an enzyme that catalyzes the chemical reaction acetyl- ... Benveniste R, Davies J (1971). "Enzymatic acetylation of aminoglycoside antibiotics by Escherichia coli carrying an R factor". ...
*  Aminoglycoside N3'-acetyltransferase
Other names in common use include 3'-aminoglycoside acetyltransferase, and 3-N-aminoglycoside acetyltransferase. Davies J, ... In enzymology, an aminoglycoside N3'-acetyltransferase (EC 2.3.1.81) is an enzyme that catalyzes the chemical reaction acetyl- ... 3-N-acetyltransferase with broad specificity that determines resistance to the novel aminoglycoside apramycin". Antimicrob. ... O'Connor S (1978). "Enzymatic modification of aminoglycoside antibiotics: ...
*  Amikacin
Variations of aminoglycoside acetyltransferase (AAC) and aminoglycoside adenylyltransferase (AAD) also confer resistance: ... an allergy to one aminoglycoside also confers hypersensitivity to other aminoglycosides). It should also be avoided in those ... Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side ... Though amikacin can be inactivated by other beta-lactams, though not to the extent as other aminoglycosides, and is still often ...
*  Streptomyces mashuensis
Aminoglycoside Antibiotics. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-68579-X. CS1 maint: Extra text: authors ...
*  Streptomyces kasugaensis
Aminoglycoside Antibiotics. Berlin, Heidelberg: Springer Berlin Heidelberg. ISBN 3-642-68579-X. CS1 maint: Extra text: authors ... "Mechanism of multiple aminoglycoside resistance of kasugamycin-producing Streptomyces kasugaensis MB273: involvement of two ...
*  Kanamycin kinase
Aminoglycoside-3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an enzyme that primarily catalyzes the ... Aminoglycoside resistance genes are commonly used in the realm of genetic engineering in order to select for correctly ... Antibiotics, such as the aminoglycosides kanamycin or neomycin, are added to the cultures during growth phases in order to ... However, APH(3') has also been found to phosphorylate at the 5'-hydroxyl group in 4,5-disubstituted aminoglycosides, which lack ...
*  Kingella kingae
Options include aminoglycosides, macrolides and fluoroquinolones. K.Kingae can also cause infectious endocarditis, in children ...
*  Anaerobic infection
Aminoglycosides or colistin may be required. Antimicrobial regimens for children include an aminoglycoside-based regimen, a ... The routine use of an aminoglycoside or another second agent effective against gram-negative facultative and aerobic bacilli is ... aminoglycosides, and the earlier quinolones. Some infections are more likely to be caused by anaerobic bacteria, and they ... aminoglycoside) or an anti-pseudomonal cephalosporin (i.e. cefepime ) are generally added to metronidazole, and occasionally ...
*  Gentamicin
Kidney damage is a problem in 10-25% of people who receive aminoglycosides, and gentamicin is one of the most nephrotoxic of ... Gentamicin is a type of aminoglycoside. It works by stopping the bacteria from making protein, which typically kills the ... 11% of the population who receives aminoglycosides experience damage to their inner ear. The common symptoms of inner ear ... This mechanism of action is similar to other aminoglycosides. Gentamicin is composed of a number of related gentamicin ...
*  Dizocilpine
NMDA antagonists like dizocilpine have been shown in animal models to attenuate the hearing loss caused by aminoglycosides It ... Ernfors P, Canlon B (December 1996). "Aminoglycoside excitement silences hearing". Nat. Med. 2 (12): 1313-4. doi:10.1038/nm1296 ... "N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss". Nat. Med. 2 (12): 1338-43. doi:10.1038/ ... is thought that aminoglycosides mimic endogenous polyamines at NMDA receptors and produce excitotoxic damage, leading to hair ...
*  Multidrug tolerance
... "the generation of a proton-motive force which facilitates aminoglycoside uptake". Phage therapy, where applicable, entirely ... "Metabolite-enabled eradication of bacterial persisters by aminoglycosides". Nature. 473 (7346): 216-220. doi:10.1038/ ...
*  Micromonospora sagamiensis
It produces sagamicin, an aminoglycoside antibiotic, as well as several mutational variants. Its cell wall contains only D- ... Kase, Hiroshi; Odakura, Yoshihiro; Nakayama, Kiyoshi (1982). "Sagamicin and the related aminoglycosides: Fermentation and ...
*  Burkholderia vietnamiensis
It differs from most Burkholderia species in that it is often susceptible to aminoglycosides, but not polymyxin B. Many ... "In vitro susceptibility of Burkholderia vietnamiensis to aminoglycosides". Antimicrob. Agents Chemother. 55 (5): 2256-64. doi: ...
*  Beta-lactamase
Some patients have responded to aminoglycoside or quinolone therapy, but, in a recent comparison of ciprofloxacin and imipenem ... Resistance to fluoroquinolones and aminoglycosides is especially high. For infections caused by ESBL-producing Escherichia coli ... Associated resistance to aminoglycosides and trimethoprim-sulfamethoxazole, as well as high frequency of co-existence of ... aminoglycosides). Therefore, antibiotic options in the treatment of ESBL-producing organisms are extremely limited. Carbapenems ...
*  Protein synthesis inhibitor
Macrolides, clindamycin and aminoglycosides (with all these three having other potential mechanisms of action as well), have ... Aminoglycosides, among other potential mechanisms of action, interfere with the proofreading process, causing increased rate of ... Retapamulin Mupirocin Fusidic acid The following antibiotics bind to the 30S subunit of the ribosome: Aminoglycosides ... Flavio Guzmán (12/08/2008). "Protein synthesis inhibitors: aminoglycosides mechanism of action animation. Classification of ...
*  Mequitazine
Can mask signs of ototoxicity caused by aminoglycosides. QT prolongation (which can lead to torsades de pointes arrhythmia) ...
*  Proofreading (biology)
Pharmamotion --> Protein synthesis inhibitors: aminoglycosides mechanism of action animation. Classification of agents Posted ...
*  Micronomicin
... (INN) is an aminoglycoside antibiotic for use on the eye. Odakura, Y.; Kase, H.; Nakayama, K. (1983). "Sagamicin ... and the related aminoglycosides: Fermentation and biosynthesis. III. Isolation and characterization of Micromonospora ...
*  Antibiotics
Allison KR, Brynildsen MP, Collins JJ (2011). "Metabolite-enabled eradication of bacterial persisters by aminoglycosides". ...
*  Streptoduocin
... is an aminoglycoside antibiotic. It is a mixture of streptomycin and dihydrostreptomycin. SHUBIN H, HEIKEN CA, ...
*  Netilmicin
Nonparallel nephrotoxicity dose-response curves of aminoglycosides: Nephrotoxicity comparisons of aminoglycosides in rats, ... Netilmicin is a member of the aminoglycoside family of antibiotics. These antibiotics have the ability to kill a wide variety ... Daily single-dose aminoglycoside administration. Therapeutic and economic benefits: Animal studies have shown that dosing ... Relative efficacy and toxicity of netilmicin and tobramycin in oncology patients: We conclude that aminoglycoside-associated ...