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*  Aromaticity
Aromatic compounds play key roles in the biochemistry of all living things. The four aromatic amino acids histidine, ... Aromatization Aromatic hydrocarbon Aromatic amine Simple aromatic ring Pi interaction Avoided crossing Aromatic ring current ... The molecule heme contains an aromatic system with 22 π-electrons. Chlorophyll also has a similar aromatic system. Aromatic ... Aromatic compounds undergo electrophilic aromatic substitution and nucleophilic aromatic substitution reactions, but not ...
*  Essential amino acid
... amino acids are sometimes considered a single pool of nutritionally equivalent amino acids as are the aromatic amino acid pair ... An essential amino acid, or indispensable amino acid, is an amino acid that cannot be synthesized de novo (from scratch) by the ... Cysteine (or sulphur-containing amino acids), tyrosine (or aromatic amino acids), and arginine are always required by infants ... amino acids Low-protein diet Orthomolecular medicine Protein Digestibility Corrected Amino Acid Score Ketogenic amino acid ...
*  Aromatic amino acid
An aromatic amino acid (AAA) is an amino acid that includes an aromatic ring. Examples include: Among 20 standard amino acids: ... Aromatic amino acids are able to absorb light due to their conjugated double bonds. This characteristic of aromatic amino acids ... Animals obtain aromatic amino acids from their diet, but all plants and micro-organisms must synthesize their aromatic amino ... These aromatic amino acids are the derivatives of many secondary metabolites, all essential to a plant's biological functions, ...
*  Aromatic-amino-acid transaminase
... an aromatic-amino-acid transaminase (EC 2.6.1.57) is an enzyme that catalyzes the chemical reaction an aromatic amino acid + 2- ... an aromatic oxo acid + L-glutamate Thus, the two substrates of this enzyme are aromatic amino acid and 2-oxoglutarate, whereas ... Other names in common use include aromatic amino acid aminotransferase, aromatic aminotransferase, and ArAT. This enzyme ... Mavrides C, Orr W (1975). "Multispecific aspartate and aromatic amino acid aminotransferases in Escherichia coli". J. Biol. ...
*  Aromatic L-amino acid decarboxylase
... inhibitor, a class of anti-Parkinson drugs Aromatic amino acids Histidine decarboxylase PDB ... Aromatic-L-Amino-Acid Decarboxylases at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... Aromatic L-amino acid decarboxylase (AADC or AAAD), also known as DOPA decarboxylase (DDC), tryptophan decarboxylase, and 5- ... "Aromatic L-amino acid decarboxylase deficiency: clinical features, treatment, and prognosis". Neurology. 62 (7): 1058-65. doi: ...
*  Aromatic-amino-acid-glyoxylate transaminase
... an aromatic oxo acid + glycine Thus, the two substrates of this enzyme are aromatic amino acid and glyoxylate, whereas its two ... an aromatic-amino-acid-glyoxylate transaminase (EC 2.6.1.60) is an enzyme that catalyzes the chemical reaction an aromatic ... The systematic name of this enzyme class is aromatic-amino-acid:glyoxylate aminotransferase. Harada I, Noguchi T, Kido R (1978 ... "Purification and characterization of aromatic-amino-acid-glyoxylate aminotransferase from monkey and rat liver". Hoppe-Seyler's ...
*  Biopterin-dependent aromatic amino acid hydroxylase
... s (AAAH) are a family of aromatic amino acid hydroxylase enzymes which ... Each AAAH enzyme contains iron and catalyzes the ring hydroxylation of aromatic amino acids using tetrahydrobiopterin (BH4) as ... functional domains and evolution of aromatic amino acid hydroxylases". Proc. Natl. Acad. Sci. U.S.A. 84 (16): 5530-4. doi: ... In humans, phenylalanine hydroxylase deficiency can cause phenylketonuria, the most common inborn error of amino acid ...
*  Aromatic L-amino acid decarboxylase inhibitor
An aromatic L-amino acid decarboxylase inhibitor (synonyms: DOPA decarboxylase inhibitor, DDCI and AAADI) is a drug which ... inhibits the synthesis of dopamine by the enzyme aromatic L-amino acid decarboxylase (AADC, AAAD, or DOPA decarboxylase). ...
*  Branched-chain amino acid aminotransferase
"Branched-chain and aromatic amino acid catabolism into aroma volatiles in Cucumis melo L. fruit". Journal of Experimental ... Branched-chain amino acids (BCAA) are ubiquitous in many organisms, comprising 35% of all proteins and 40% of the amino acids ... The branched-chain amino acid aminotransferases help to produce compounds like isovaleric acid, isobutyric acid, 2- and 3- ... Branched-chain amino acid aminotransferase (BCAT), also known as branched-chain amino acid transaminase, is an aminotransferase ...
*  Phenylalanine
Sprenger GA (2007). "Aromatic Amino Acids". Amino Acid Biosynthesis: Pathways, Regulation and Metabolic Engineering (1st ed.). ... In excessive quantities, supplementation can interfere with the production of serotonin and other aromatic amino acids as well ... which naturally produces aromatic amino acids like phenylalanine. The quantity of L-phenylalanine produced commercially has ... The corresponding enzymes in for those compounds are the aromatic amino acid hydroxylase family and nitric oxide synthase. ...
*  Aromatic acid
Phenolic acids: substances containing an aromatic ring and an organic carboxylic acid function (C6-C1 skeleton). Aromatic amino ... Aromatic acids are a type of aromatic compound. Included in that class are substances containing an aromatic ring and an ... organic acid functional group. There are several categories of aromatic acids including: ...
*  Amino acid synthesis
This acts in the cell by monitoring the concentrations of each of the three aromatic amino acids. When there is too much of any ... Amino acids that must be obtained from the diet are called essential amino acids. Nonessential amino acids are produced in the ... Amino acid synthesis is the set of biochemical processes (metabolic pathways) by which the various amino acids are produced ... Most amino acids are synthesized from α-ketoacids, and later transaminated from another amino acid, usually glutamate. The ...
*  Phenylalanine decarboxylase
Schulz AR, Oliner L (1967). "The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis". Life ... LOVENBERG W, WEISSBACH H, UDENFRIEND S (1962). "Aromatic L-amino acid decarboxylase". J. Biol. Chem. 237: 89-93. PMID 14466899 ... aromatic L-amino acid decarboxylase, and L-phenylalanine carboxy-lyase. This enzyme participates in phenylalanine metabolism. ...
*  Pteridine reductase
Fitzpatrick PF (2000). "The aromatic amino acid hydroxylases". Adv. Enzymol. Relat. Areas Mol. Biol. Advances in Enzymology - ...
*  Nitisinone
Metabolism of Aromatic Amino Acids and Amines. Methods in Enzymology. 142. pp. 139-42. doi:10.1016/S0076-6879(87)42021-1. ISBN ... It has been demonstrated that treatment with nitisinone can reduce urinary levels of homogentisic acid in alkaptonuria patients ... for patients with Tyrosinemia type 1 as it prevents the formation of maleylacetoacetic acid and fumarylacetoacetic acid, which ...
*  DAHP synthase
Herrmann, K.; Entus, R. (2001). "Shikimate Pathway: Aromatic Amino Acids and Beyond". Encyclopedia of Life Sciences. doi: ... each of which sensitive to one of the amino acids produced in the shikimate pathway. In a study of DAHP synthase sensitive to ... which is responsible for the biosynthesis of the amino acids phenylalanine, tyrosine, and tryptophan. Since it is the first ... 2-keto-3-deoxy-D-arabino-heptonic acid 7-phosphate synthetase, 3-deoxy-D-arabino-2-heptulosonic acid 7-phosphate synthetase, 3- ...
*  Phenylalanine hydroxylase
PAH is one of three members of the biopterin-dependent aromatic amino acid hydroxylases, a class of monooxygenase that uses ... Flatmark T, Stevens RC (Aug 1999). "Structural Insight into the Aromatic Amino Acid Hydroxylases and Their Disease-Related ... PAH is unusual among the aromatic amino acid hydroxylases for its involvement in catabolism; tyrosine and tryptophan ... Fitzpatrick PF (Dec 2003). "Mechanism of aromatic amino acid hydroxylation". Biochemistry. 42 (48): 14083-91. doi:10.1021/ ...
*  3-dehydroquinate dehydratase
... meaning that they must obtain these essential amino acids through their diet. Aromatic Amino acids include Phenylalanine, ... The aromatic amino acids produced by the shikimate acid pathway are used by higher plants as protein building blocks and as ... The shikimate pathway was determined to be a major biosynthetic route for the production of aromatic amino acids through the ... The shikimate pathway is a biosynthetic pathway that allows plants, fungi, and bacteria to produce aromatic amino acids. ...
*  List of OMIM disorder codes
CYP19A1 Aromatic L-amino acid decarboxylase deficiency; 608643; DDC Arrhythmogenic right ventricular dysplasia 1; 107970; TGFB3 ... FREM1 Bile acid malabsorption, primary; 613291; SLC10A2 Bile acid synthesis defect, congenital, 2; 235555; AKR1D1 Bile acid ... SBDS Sialic acid storage disorder, infantile; 269920; SLC17A5 Sialidosis, type I; 256550; NEU1 Sialidosis, type II; 256550; ... SLC7A7 Lysosomal acid phosphatase deficiency; 200950; ACP2 Lysyl hydroxylase 3 deficiency; 612394; PLOD3 Machado-Joseph disease ...
*  Phenibut
... is a synthetic aromatic amino acid. It is a chiral molecule and thus has two potential configurations, as (R)- and (S ... Owen DR, Wood DM, Archer JR, Dargan PI (2016). "Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, ... As such, its chemical name is β-phenyl-γ-aminobutyric acid, which can be abbreviated as β-phenyl-GABA. The presence of the ... Phenibut is structurally related to the neurotransmitter γ-aminobutyric acid (GABA), and hence is a GABA analogue. It is ...
*  L-DOPA
Once L-DOPA has entered the central nervous system, it is converted into dopamine by the enzyme aromatic L-amino acid ... Dopamine is formed by the decarboxylation of L-DOPA by aromatic L-amino acid decarboxylase (AADC). L-DOPA can be directly ... "Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology" (PDF). Clinical Chemistry. 38 (12): 2405-10. PMID ... L-DOPA is produced from the amino acid L-tyrosine by the enzyme tyrosine hydroxylase. It is also the precursor for the ...
*  Melanomorph
... s originate from the aromatic amino acids tyrosine, tryptophan, and phenylalanine. They tend to absorb ultraviolet-B ...
*  Glyphosate
Maeda H, Dudareva N (2012). "The shikimate pathway and aromatic amino Acid biosynthesis in plants". Annual Review of Plant ... and like all amino acids, exists in different ionic states depending on pH. Both the phosphonic acid and carboxylic acid ... an essential precursor for the amino acids mentioned above. These amino acids are used in protein synthesis and to produce ... It inhibits a plant enzyme involved in the synthesis of three aromatic amino acids: tyrosine, tryptophan, and phenylalanine. ...
*  Chorismic acid
ISBN 0-19-864226-1. Gibson, F. (1999). "The elusive branch-point compound of aromatic amino acid biosynthesis". Trends in ... It is a precursor for: The aromatic amino acids phenylalanine, tryptophan, and tyrosine Indole, indole derivatives and ... Chorismate is transformed into para-aminobenzoic acid by the enzymes 4-amino-4-deoxychorismate synthase and 4-amino-4- ... because the compound plays a role as a branch-point in aromatic amino acid biosynthesis. Shikimate → shikimate-3-phosphate → 5- ...
*  Meta-Tyramine
"EC 4.1.1.28 - Aromatic-L-amino-acid decarboxylase (Homo sapiens)". BRENDA. Technische Universität Braunschweig. July 2016. ... meta-Tyramine is produced in humans via aromatic amino acid decarboxylase-mediated metabolism of meta-tyrosine. meta-Tyramine ...
*  Neocarzinostatin
Although, from the aromatic structure of naphthoic acid moiety, it might appear that it is synthesized by a type II PKS, the ... It consists of two parts, a labile chromophore (the non-protein molecular entity shown at right) and a 113 amino acid protein ... The second type I PKS gene NcsB codes for the naphthoic acid moiety. Additionally, a cluster of NcsC genes are responsible for ... 2.Synthesis of naphthoic acid moiety: A group of four genes, namely, NcsB, NcsB1, NcsB2 and NcsB3 encode enzymes for the ...
*  EPSP synthase
Eventually this results in organism death from lack of aromatic amino acids the organism requires to survive. A version of the ... Maeda H, Dudareva N (2012). "The shikimate pathway and aromatic amino Acid biosynthesis in plants". Annual Review of Plant ... Jaworski EK (1972). "Mode of action of N-phosphonomethyl-glycine: inhibition of aromatic amino acid biosynthesis". J Agric Food ... EPSP synthase participates in the biosynthesis of the aromatic amino acids phenylalanine, tyrosine and tryptophan via the ...