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*  SLC1A1
... amino-acid transporter 3 is a member of the high-affinity glutamate transporters which plays an essential role in transporting ... "Entrez Gene: SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1". ... SLC1A1, also known as excitatory amino-acid transporter 3 (EAAT3), is a protein that in humans is encoded by the SLC1A1 gene. ... Excitatory amino acid transporter Glutamate transporter Solute carrier family GRCh38: Ensembl release 89: ENSG00000106688 - ...
*  AAAP family
"Coupled and uncoupled proton movement by amino acid transport system N". EMBO Journal. 20 (24): 7041-51. doi:10.1093/emboj/ ... Since Systems A are electrogenic which Systems N are not, the amino acid:cation stoichiometries may differ. Fischer, WN; Loo, ... "Low and high affinity amino acid H+-cotransporters for cellular import of neutral and charged amino acids". Plant Journal. 29 ( ... Six AAAPs in A. thaliana are well characterized and transport neutral and charged amino acids with varying specificities and ...
*  SLC6A19
"Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder". J. ... SLC6A19 is a system B(0) transporter that mediates epithelial resorption of neutral amino acids across the apical membrane in ... Solute carrier family 6 member 19 also known as the sodium-dependent neutral amino acid transporter B(0)AT1 or system B(0) ... Bröer S (January 2008). "Amino acid transport across mammalian intestinal and renal epithelia". Physiol. Rev. 88 (1): 249-286. ...
*  SLC7A11
... is a member of a heterodimeric Na+-independent anionic amino acid transport system highly specific for cystine and ... the amino acid transport activity system xc-". Pflugers Archiv. 442 (2): 286-96. doi:10.1007/s004240100537. PMID 11417227. ... the light chain of amino acid transport system xc-". Antioxidants & Redox Signaling. 2 (4): 665-71. doi:10.1089/ars.2000.2.4- ... "Entrez Gene: SLC7A11 solute carrier family 7, (cationic amino acid transporter, y+ system) member 11". Lutgen V, Resch J, ...
*  SLC38A2
Jones HN, Ashworth CJ, Page KR, McArdle HJ (2006). "Cortisol stimulates system A amino acid transport and SNAT2 expression in a ... "Transcriptional control of the human sodium-coupled neutral amino acid transporter system A gene by amino acid availability is ... 2006). "Amino acid starvation induces the SNAT2 neutral amino acid transporter by a mechanism that involves eukaryotic ... 2006). "Characterization of the amino acid response element within the human sodium-coupled neutral amino acid transporter 2 ( ...
*  SLC1A5
Kudo Y, Boyd CA (August 2002). "Changes in expression and function of syncytin and its receptor, amino acid transport system B( ... Neutral amino acid transporter B(0) is a protein that in humans is encoded by the SLC1A5 gene. Glutamate transporter Solute ... "Entrez Gene: SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5". Tailor CS, Nouri A, Zhao Y, Takeuchi Y ... Uchiyama T, Matsuda Y, Wada M, Takahashi S, Fujita T (April 2005). "Functional regulation of Na+-dependent neutral amino acid ...
*  GcvB RNA
... encodes a small non-coding RNA involved in the regulation of a number of amino acid transport systems as well as amino acid ... GcvB RNA also is involved in regulating a variety of genes involved in amino acid biosynthesis such as ilvC, gdhA, thrL and ... "The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in ... "The gcvB gene encodes a small untranslated RNA involved in expression of the dipeptide and oligopeptide transport systems in ...
*  SLC3A2
Amino Acid Transport System L at the US National Library of Medicine Medical Subject Headings (MeSH) This article incorporates ... "Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid ... "Entrez Gene: SLC3A2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2". Kucharzik T, ... Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y (2004). "CATs and HATs: the SLC7 family of amino acid transporters ...
*  List of MeSH codes (D12.776.157)
... amino acid transport systems, acidic MeSH D12.776.157.530.200.249.500 -- amino acid transport system x-ag MeSH D12.776.157.530. ... amino acid transport system a MeSH D12.776.157.530.200.500.200 -- amino acid transport system asc MeSH D12.776.157.530.200.500. ... amino acid transport systems, basic MeSH D12.776.157.530.200.374.600 -- amino acid transport system y+ MeSH D12.776.157.530. ... cationic amino acid transporter 2 MeSH D12.776.157.530.200.374.750 -- amino acid transport system y+l MeSH D12.776.157.530. ...
*  Photorhabdus luminescens
... encodes a small non-coding RNA involved in the regulation of a number of amino acid transport systems as well as amino acid ...
*  CD98
Amino Acid Transport System L at the US National Library of Medicine Medical Subject Headings (MeSH). ... Verrey F, Closs EI, Wagner CA, Palacin M, Endou H, Kanai Y (2004). "CATs and HATs: the SLC7 family of amino acid transporters ... CD98 is a glycoprotein that is a heterodimer composed of SLC3A2 and SLC7A5 that forms the large neutral amino acid transporter ... Boado RJ, Li JY, Nagaya M, Zhang C, Pardridge WM (1999). "Selective expression of the large neutral amino acid transporter at ...
*  Gamma-Amino-beta-hydroxybutyric acid
... and l-γ-Amino-β-Hydroxybutyric Acids in GABA Receptor and Transport Test Systems" (pdf). Journal of Neuroscience. 1 (2): 132- ... γ-Amino-β-hydroxybutyric acid (GABOB), also known as β-hydroxy-γ-aminobutyric acid (β-hydroxy-GABA), and sold under the brand ... Effect of gamma-amino-beta-hydroxybutyric acid (GABHB) on experimentally-induced epileptic activity]" [Effect of γ-amino-β- ... García-Flores E, Farías R (1997). "γ-Amino-β-hydroxybutyric acid as add-on therapy in adult patients with severe focal epilepsy ...
*  SLC38A1
"Characterization of an N-system amino acid transporter expressed in retina and its involvement in glutamine transport". J. Biol ... Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene. Amino acid ... 2007). "Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic ... a subtype of amino acid transporter A, from human placenta". Biochem Biophys Res Commun. 273 (3): 1175-9. doi:10.1006/bbrc. ...
*  Expanded genetic code
... but often the various transport systems can handle unnatural amino acids with apolar side-chains. In the second case, a ... while the added amino acids are called non-standard amino acids (NSAAs), or unnatural amino acids (uAAs; term not used in ... or non-canonical amino acids. The first element of the system is the amino acid that is added to the genetic code of a certain ... An amino acid auxotrophic expression host is supplemented with an amino acid analog during target protein expression. This ...
*  Serotonin-norepinephrine reuptake inhibitor
Serotonin is synthesized from an amino acid called L-tryptophan. Active transport system regulates the uptake of tryptophan ... The same motif can be found in reboxetine where it is constrained in a morpholine ring system. Some studies have been made ... 150 mg/day), it acts on serotonergic and noradrenergic systems, whereas at high doses (>300 mg/day), it also affects ... Although the perception and transmission of pain stimuli in the central nervous system have not been fully elucidated, ...
*  SLC7A3
... is a member of the system y+ family of transporters characterized by sodium-independent transport of cationic amino acids.[ ... "Entrez Gene: SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3". Hosokawa H, Sawamura T, ... Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene. SLC7A3 ... Ito K, Groudine M (1997). "A new member of the cationic amino acid transporter family is preferentially expressed in adult ...
*  Blood-brain barrier
... as well as the selective transport of molecules such as glucose and amino acids that are crucial to neural function. ... "Lipoic acid affects cellular migration into the central nervous system and stabilizes blood-brain barrier integrity". J. ... No difference in brain uptake of glucose, amino acids, organic acids, purines, nucleosides, or choline was observed between ... Other methods used to get through the BBB may entail the use of endogenous transport systems, including carrier-mediated ...
*  Membrane transport protein
This transport system normally removes cysteine from the fluid destined to become urine and returns this essential amino acid ... such as glucose or amino acids. When the lipid bilayer is impermeable to the molecule needing transport, active transport is ... Excitatory amino acid transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including ... Unlike channel proteins which only transport substances through membranes passively, carrier proteins can transport ions and ...
*  4-Methylpregabalin
... it was discovered that pregabalin is actively transported across the blood-brain barrier by the system L neutral amino acid ... which usually functions to transport certain amino acids, including leucine, valine and isoleucine, into the brain. This ... were found to also dramatically reduce binding to the system L transporter, and with no assisted transport into the brain, ... and also retained similar affinity for the system L transporter. This was tested in animals and as hoped, was found to have ...
*  SLC7A9
... a disease that leads to cystine stones in the urinary system due to impaired transport of cystine and dibasic amino acids. ... This protein plays a role in the high-affinity and sodium-independent transport of cystine and neutral and dibasic amino acids ... Solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 also known as SLC7A9 is a protein which in ... Heterodimeric amino acid transporter Solute carrier family "SLC7A9". Feliubadaló L, Font M, Purroy J, Rousaud F, Estivill X, ...
*  Circulatory system
... is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, ... Also, the digestive system works with the circulatory system to provide the nutrients the system needs to keep the heart ... organ system for circulating blood in animals The circulatory system, also called the cardiovascular system or the vascular ... some invertebrate groups have an open cardiovascular system. The lymphatic system, on the other hand, is an open system ...
*  Sodium-solute symporter
The solutes transported may be sugars, amino acids, organo cations such as choline, nucleosides, inositols, vitamins, urea or ... The mutant system thus behaves as a glucose-gated H+ channel. Proteins of the SSS vary in size from about 400 residues to about ... Quick M1, Loo DD, Wright EM., M; Loo, DD; Wright, EM (January 19, 2001). "Neutralization of a conserved amino acid residue in ... Sodium/substrate symport (or co-transport) is a widespread mechanism of solute transport across cytoplasmic membranes of pro- ...
*  Small intestine
Sodium bicarbonate is absorbed by active transport and glucose and amino acid co-transport. Fructose is absorbed by facilitated ... are an important part of the digestive tract's local immune system. They are part of the lymphatic system, and provide a site ... splits one amino acid at a time. Aminopeptidase and dipeptidase free the end amino acid products. Lipids (fats) are degraded ... The epithelial cells of the villi transport nutrients from the lumen of the intestine into these capillaries (amino acids and ...
*  Solute carrier family 38 member 5
The protein encoded by this gene is a system N sodium-coupled amino acid transporter. The encoded protein transports glutamine ... but does not transport charged amino acids, imino acids, or N-alkylated amino acids. Alternative splicing results in multiple ...
*  Phytotoxin
The plants are slowly starved of these amino acids and eventually DNA synthesis stops. ESPS Inhibitors affect grasses and ... They are medically important by interfering with components of the nervous system affecting membrane transport, protein ... ALS Inhibitors affect grasses and dicots by inhibiting the first step in some amino acid synthesis, acetolactate synthesis. ... Alkaloids are derived from amino acids, and contain nitrogen. ...
*  Susan K. Gilmour
She has begun evaluating new approaches to disrupting the transport system through which polyamines can be imported into cancer ... Amino Acids. 2014 Mar;46(3):543-52. Epub 2013 Jul 25. http://www.limr.org/doc/Page.asp?PageID=DOC004139 http://www. ... with an inhibitor of the polyamine transport system not only blocks tumor growth but also promotes anticancer immune responses ...
*  Reabsorption
However, glucose, amino acids, inorganic phosphate, and some other solutes are reabsorbed via secondary active transport ... Renin-angiotensin system: 1. The kidneys sense low blood pressure. 2. Release renin into the blood. 3. Renin causes production ... Reabsorption allows many useful solutes (primarily glucose and amino acids), salts and water that have passed through Bowman's ... This happens as a result of sodium transport from the lumen into the blood by the Na+/K+ATPase in the basolateral membrane of ...