August 2016). "Genetic risk factors for the posterior cortical atrophy variant of Alzheimer's disease". Alzheimer's & Dementia ... The data can be summarized as 1) loss of function of ABCA7 is associated with a risk for late onset Alzheimer's disease, 2) one ... Bhatia S, Fu Y, Hsiao JT, Halliday GM, Kim WS (December 2017). "Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White ... Bhatia S, Fu Y, Hsiao JT, Halliday GM, Kim WS (December 2017). "Deletion of Alzheimer's Disease Risk Gene ABCA7 Alters White ...
The Japanese MCI Screen for Early Detection of Alzheimer's Disease and Related Disorders. The American Journal of Alzheimer's ... memory loss due to multiple underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others. ... Journal of Alzheimer's Disease. 2007; 11(3):323-335. Ai Cho, Mika Sugimura, Seigo Nakano, Tatsuo Yamada. Early Detection and ... Disease and Other Dementias. 2008; June/July (in press). (Articles with a promotional tone from April 2014, All articles with a ...
Journal of Alzheimer's Disease. 41 (1): 15-28. doi:10.3233/jad-132357. PMID 24577481. "Cohen-Mansfield Agitation Inventory". ... American Journal of Alzheimer's Disease and Other Dementias. 32 (5): 265-271. doi:10.1177/1533317517703478. PMID 28468553. ... Cohen-Mansfield, J. (2000). "Theoretical Frameworks for Behavioral Problems in Dementia". Alzheimer's Care Today. 1. Cohen- ... the Alzheimer's Association, the Agency for Healthcare Research and Quality, the Israel Science Foundation, and the Minerva ...
"Alzheimer disease with cerebrovascular disease and vascular dementia: clinical features and course compared with Alzheimer ... Mixed dementia is diagnosed when people have evidence of Alzheimer's disease and cerebrovascular disease, either clinically or ... Unlike Alzheimer's disease, which weakens the patient, causing them to succumb to bacterial infections like pneumonia, vascular ... They tend to have better free recall and fewer recall intrusions when compared with patients with Alzheimer's disease. In the ...
Alzheimer's disease, Huntington's disease). Many of the SPM are metabolites of omega-3 fatty acids and have been proposed to be ... Alzheimer's disease, inflammatory bowel disease, etc. (see Inflammation § Disorders) may reflect, in part, a failure in this ... "Role of docosahexaenoic acid in the modulation of glial cells in Alzheimer's disease". Journal of Neuroinflammation. 13 (1): 61 ... Lyme disease, Toxoplasma gondii disease, and corneal injury. These studies indicate that the suppression of inflammation is a ...
The Biochemical Basis for a Diagnosis of Alzheimer's Disease". Journal of Alzheimer's Disease. 24 (s2): 5-16. doi:10.3233/jad- ... Papadopoulos, V.; Lecanu, L. (2011-12-20). "Caprospinol: Discovery of a Steroid Drug Candidate to Treat Alzheimer's Disease ... At USC his research focuses on Leydig cell development and the role of TSPO in non-alcoholic fatty liver disease. ... Additional research has focused on neurosteroids in the brain, adipose tissue, and nonalcoholic fatty liver disease. In 1988, ...
... has long been known as a characteristic of Alzheimer's Disease (AD), although its exact role in the disease remains ... including Alzheimer's disease, Korsakoff's syndrome, multiple system atrophy, prion disease, multiple sclerosis, AIDS dementia ... "Astrocytes in Alzheimer's disease". Neurotherapeutics. 7 (4): 399-412. doi:10.1016/j.nurt.2010.05.017. PMC 5084302. PMID ... Gliosis has historically been given a negative connotation due to its appearance in many CNS diseases and the inhibition of ...
"Microbes and Alzheimer's Disease". Journal of Alzheimer's Disease. 51 (4): 979-984. doi:10.3233/JAD-160152. ISSN 1875-8908. PMC ... "Do Microbes Trigger Alzheimer's Disease?". The Scientist. Retrieved 2018-04-30. "Drawbacks and benefits of using saliva for ... Her work on HSV has led towards understanding the HSV-APP connections and its role in Alzheimer's disease. In 2004, Bearer ... Bearer, Elaine L. (2012). "HSV, axonal transport and Alzheimer's disease: in vitro and in vivo evidence for causal ...
"Saak Ovsepian, Ph.D. , Journal of Alzheimer's Disease". www.j-alz.com. Retrieved 2023-04-14. "Saak Ovsepian". scholar.google. ... Zaborszky, Laszlo; Ovsepian, Saak V. (2024-06-01). Acetylcholine in Alzheimer's Disease and Related Dementias. Elsevier Science ... neurodegenerative and neuropsychiatric diseases, and biomarkers of brain diseases. He employs advanced imaging and ... Neurodegenerative Disease Research Award to lead REMOPD consortium in Parkinson's Disease research. In 2022, he was elected as ...
A New Target for the Treatment of Alzheimer's Disease". Journal of Alzheimer's Disease. 45 (4): 985-1000. doi:10.3233/JAD- ... and in some cases other diseases, such as Alzheimer's disease, and by brain aging. Various cognitive enhancement options - e.g ... cognition-related changes that protect against Alzheimer's disease, disease resistances, higher lean muscle mass and enhanced ... Memantine is an NMDA receptor antagonist and is used to treat patients with moderate to severe Alzheimer's disease, but is also ...
Chiang PK, Lam MA, Luo Y (September 2008). "The many faces of amyloid β in Alzheimer's disease". Current Molecular Medicine. 8 ... Hammer ND, Wang X, McGuffie BA, Chapman MR (May 2008). "Amyloids: friend or foe?". Journal of Alzheimer's Disease. 13 (4): 407- ... July 2017). "Cryo-EM structures of tau filaments from Alzheimer's disease". Nature. 547 (7662): 185-190. Bibcode:2017Natur.547 ... "Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases". IUBMB Life. 59 (4-5): 332-45. doi: ...
As MCI may represent a prodromal state to clinical Alzheimer's disease, treatments proposed for Alzheimer's disease, such as ... treat Alzheimer's disease have been assessed for their ability to treat MCI or prevent progression to full Alzheimer's disease ... Studies suggest that these individuals tend to progress to probable Alzheimer's disease at a rate of approximately 10% to 15% ... Petersen RC, Bennett D (June 2005). "Mild cognitive impairment: is it Alzheimer's disease or not?". J. Alzheimers Dis. 7 (3): ...
Bilirubin-induced neuronal damage and Alzheimer's disease) liver-NAFLD and kidney injury associated diseases using iPS cells ( ... ISBN 978-3-030-33923-4. "James Adjaye, PhD , Journal of Alzheimer's Disease". www.j-alz.com. Retrieved 2022-03-07. "Institut ... lines from a female and male Alzheimer's disease patient expressing different copy numbers of a coding CNV in the Alzheimer ... the Journal of Alzheimer's Disease, and BMC Genomics. Some of his works include; (contrib.) Matrix Metalloproteinase 14 ...
2013). "Treatment of Alzheimer's disease with the GSK-3 inhibitor tideglusib: a pilot study". Journal of Alzheimer's Disease. ... Del Ser T (2010). "Phase IIa clinical trial on Alzheimer's disease with NP12, a GSK3 inhibitor". Alzheimer's & Dementia. 6 (4 ... Both clinical trials were discontinued in 2011 (PSP) and 2012 (Alzheimer's disease) due to lack of efficacy Tooth repair ... In a phase-IIa clinical trial for Alzheimer's disease, the treatment was discontinued, due to lack of efficacy (del Ser et al ...
Journal of Alzheimer's Disease. 57 (4): 1017-1039. doi:10.3233/JAD-160623. PMID 27662312. Mitoma, H.; Honnorat, J.; Yamaguchi, ... "Stress-induced synaptic dysfunction and neurotransmitter release in Alzheimer's Disease: Can neurotransmitters and ... Some diseases of unknown etiology have been proposed to be synaptopathies. Examples include autism spectrum disorder and ... A synaptopathy is a disease of the brain, spinal cord or peripheral nervous system relating to the dysfunction of synapses. ...
"Aluminum and Alzheimer's Disease: After a Century of Controversy, Is there a Plausible Link?". Journal of Alzheimer's Disease. ... Crapper Mclachlan, D.R.; Lukiw, W.J.; Kruck, T.P.A. (1989). "New Evidence for an Active Role of Aluminum in Alzheimer's Disease ... Aluminium has been suspected of being a possible cause of Alzheimer's disease, but research into this for over 40 years has ... Xu, N.; Majidi, V.; Markesbery, W. R.; Ehmann, W. D. (1992). "Brain aluminum in Alzheimer's disease using an improved GFAAS ...
Nitrosamines have also been shown to play a part in Alzheimer's and other neurodegenerative diseases, as well as type 1 and 2 ... Journal of Alzheimer's Disease. 17 (3): 519-529. doi:10.3233/JAD-2009-1070. PMC 4551511. PMID 19363256. Government of Canada, ... "Epidemiological Trends Strongly Suggest Exposures as Etiologic Agents in the Pathogenesis of Sporadic Alzheimer's Disease, ...
Journal of Alzheimer's Disease. 33 (Suppl 1): S35-S45. doi:10.3233/JAD-2012-129036. PMC 3532959. PMID 22751173. Babić Leko M, ... Abnormalities of TDP-43 also occur in an important subset of Alzheimer's disease patients, correlating with clinical and ... "Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease". Journal of ... Fan AC, Leung AK (2016). "RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLD". In Yeo GW (ed.). RNA ...
In more recent work, Tsai has created a lab-engineered model of the Blood-Brain Barrier to investigate how Alzheimer disease ... "Epigenomics of Alzheimer's disease progression". MIT News. Retrieved 2017-03-21. Gjoneska, Elizabeta; Pfenning, Andreas R.; ... Tsai has elucidated the role of structural and epigenetic mechanisms in Alzheimer's disease, showing in two 2015 studies that ... for her research on Alzheimer's disease and the role of CDK5 and chromatin remodeling in the progression of the disease. ...
Nehlig A (2010). "Is caffeine a cognitive enhancer?" (PDF). Journal of Alzheimer's Disease. 20 (Suppl 1): S85-94. doi:10.3233/ ... Ribeiro JA, Sebastião AM (2010). "Caffeine and adenosine". Journal of Alzheimer's Disease. 20 (Suppl 1): S3-15. doi:10.3233/JAD ... Ribeiro JA, Sebastião AM (2010). "Caffeine and adenosine". Journal of Alzheimer's Disease. 20 (Suppl 1): S3-15. doi:10.3233/JAD ... A neuroprotective effect of caffeine against Alzheimer's disease and dementia is possible but the evidence is inconclusive. ...
... implications for Alzheimer's Disease". Neurobiology of Aging. 35 (2): 309-321. doi:10.1016/j.neurobiolaging.2013.08.016. PMC ... and consequently it has been linked to different human diseases. For example autoinflammation in psoriasis disease was found to ... "Dapansutrile" (PDF). Alzheimer's Drug Discovery Foundation. November 2019. Archived (PDF) from the original on 2021-08-22. ... Problems with regulating inflammasomes have been linked to several autoimmune diseases such as type I and type II diabetes, ...
He had Alzheimer's disease. In addition to suffering with Alzheimer's disease for several years, in 2011 Mitchem was diagnosed ... with ALS, or Lou Gehrig's Disease, a fatal neuro-muscular disease with no known cause or cure. Former Sen. Hinton Mitchem dies ...
The most common form of dementia is Alzheimer's disease. Alzheimer's disease (AD) is a progressive, neurodegenerative disease ... In Alzheimer's disease, high levels of certain proteins inside and outside brain cells make it hard for brain cells to stay ... He Y, Chen Z, Gong G, Evans A (August 2009). "Neuronal networks in Alzheimer's disease". The Neuroscientist. 15 (4): 333-350. ... Brier MR, Thomas JB, Ances BM (June 2014). "Network dysfunction in Alzheimer's disease: refining the disconnection hypothesis ...
ACE's effect on Alzheimer's disease is still highly debated. Alzheimer patients usually show higher ACE levels in their brain. ... More recent research suggests that ACE inhibitors can reduce risk of Alzheimer's disease in the absence of apolipoprotein E4 ... Brooks L (2004). "The Importance of Treating the Blood Pressure: ACE Inhibitors May Slow Alzheimer's Disease". Medscape. ... 2013-01-01). "Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of ...
2015). "Anti-inflammatory drugs and risk of Alzheimer's disease: an updated systematic review and meta-analysis". Journal of ... NSAIDs should be used with caution in individuals with inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis ... "Non-steroidal anti-inflammatory drugs as a treatment for Alzheimer's disease: a systematic review and meta-analysis of ... steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease". The Cochrane Database of ...
Mild Cognitive Impairment and Alzheimer's Disease". Current Alzheimer Research. 15 (3): 219-228. doi:10.2174/ ... The Cognitive Center has been a member of the European Alzheimer Disease Consortium (EADC) since 2017, and we are currently ... Journal of Alzheimer's Disease. 55 (3): 951-964. doi:10.3233/JAD-160667. PMID 27802238. Laczó J, Andel R, Nedelska Z, Vyhnalek ... "Relation of plasma selenium and lipid peroxidation end products in patients with Alzheimer's disease". Physiol. Res. 66 (6): ...
Itzhaki, Ruth F.; Lathe, Richard (12 April 2016). "Microbes and Alzheimer's Disease". Journal of Alzheimer's Disease. 51 (4): ... "The antimicrobial protection hypothesis of Alzheimer's disease". Alzheimer's & Dementia. 14 (12): 1602-1614. doi:10.1016/j.jalz ... Lathe has also argued that infection may play a role in Alzheimer disease, and has worked with Rudy Tanzi and Rob Moir at ... Journal of Alzheimer's Disease. 64 (2): 363-366. doi:10.3233/JAD-180266. hdl:20.500.11820/63af4489-c3b6-49d9-8c50-35e7f1608450 ...
In Who's Who (2014) she did not detail her marital status beyond "married". Gorman had Alzheimer's disease. She died from end- ... People with Alzheimer's disease, Deaths from dementia in England, 20th-century English women, 20th-century English people, 21st ...
Journal of Alzheimer's Disease. 76 (1): 261-274. doi:10.3233/JAD-200087. ISSN 1387-2877. PMC 7546579. PMID 32538841. Francesco ... and Prognostic Accuracy of the Cogstate Brief Battery and Auditory Verbal Learning Test in Preclinical Alzheimer's Disease and ... "Apellis and Sobi strike a $1.25B deal in rare disease collaboration". www.bioworld.com. Retrieved 2021-08-03. (Orphaned ... utility of the cogstate brief battery in identifying cognitive impairment in mild cognitive impairment and Alzheimer's disease ...
... in the treatment of Alzheimer's disease". Journal of Alzheimer's Disease. 6 (1): 17-26. doi:10.3233/JAD-2004-6103. PMID ... Significant research has been done on Colostrinin's possible efficacy in Alzheimer's disease, the most common form of dementia ... Kubis, AM; Janusz, M (2008). "Alzheimer's disease: new prospects in therapy and applied experimental models". Postepy Higieny i ... Journal of Alzheimer's Disease. 20 (2): 423-426. doi:10.3233/JAD-2010-1382. ISSN 1875-8908. PMID 20164569. I. Boldogh; A. Bacsi ...
"New acetylcholinesterase inhibitors for Alzheimer's disease". International Journal of Alzheimer's Disease. 2012: 728983. doi: ... It has been shown to improve long-term memory, and was once explored as a therapy for Alzheimer's disease, but in clinical ... This database provides a catalog of the therapeutics currently or previously tested as treatment for Alzheimer's disease and ... Coelho F, Birks J (2001). "Physostigmine for Alzheimer's disease". The Cochrane Database of Systematic Reviews. 2001 (2): ...