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*  Exon shuffling
"Cellular inhibitors of long interspersed element 1 and Alu retrotransposition". Proc Natl Acad Sci U S A. 103 (23): 8780-8785. ... LINEs are a group of genetic elements that are found in abundant quantities in eukaryotic genomes. LINE-1 is the most common ... It is composed of the read-through Helitron element and its downstream genomic regions, flanked by a random DNA site, serving ... But since the L1 element was present in neither the retrotransposed segment nor the original sequence the mobilization of the ...
*  Alu element
Alu elements in primates form a fossil record that is relatively easy to decipher because Alu elements insertion events have a ... Alu elements are retrotransposons and look like DNA copies made from RNA polymerase III-encoded RNAs. Alu elements do not ... The Alu family is a family of repetitive elements in the human genome. Modern Alu elements are about 300 base pairs long and ... Alu) restriction endonuclease. Alu elements are the most abundant transposable elements, containing over one million copies ...
*  Retrotransposon marker
October 2003). "Alu elements and hominid phylogenetics". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 12787-91. doi:10.1073/pnas. ... The analysis of SINEs - Short INterspersed Elements - LINEs - Long INterspersed Elements - or truncated LTRs - Long Terminal ... The target sites are relatively unspecific so that the chance of an independent integration of exactly the same element into ... Hamdi H, Nishio H, Zielinski R, Dugaiczyk A (June 1999). "Origin and phylogenetic distribution of Alu DNA repeats: irreversible ...
*  Mutation
Häsler J, Strub K (November 2006). "Alu elements as regulators of gene expression". Nucleic Acids Research. Oxford University ... They are usually caused by transposable elements, or errors during replication of repeating elements. Insertions in the coding ... For example, more than a million copies of the Alu sequence are present in the human genome, and these sequences have now been ... Insertions can be reversed by excision of the transposable element. (Point) deletions remove one or more nucleotides from the ...
*  C10orf76
325 L V T T P V S P A P T T P V T P L G T T P P S S 359 An Alu element was identified in the 3`-UTR of the longest mRNA ... Häsler J, Strub K (2006). "Alu elements as regulators of gene expression". Nucleic Acids Research. 34 (19): 5491-7. doi:10.1093 ... Also, an Alu segment in the 3 prime untranslated region of the mature mRNA could serve as a potential translational regulatory ... but there is existing evidence for Alu-mediated protein translation regulation, so this cannot be ruled out in c10orf76. The N- ...
*  Jerzy Jurka
... including the discovery of the major families of Alu elements. He also proposed the mechanism of Alu proliferation and ... June 2002). "Active Alu elements are passed primarily through paternal germlines". Theoretical Population Biology. 61 (4): 519- ... The Erdős Project, "Paths to Erdős" Jurka J, Smith T (July 1988). "A fundamental division in the Alu family of repeated ... In 2006 they reported a study of a new, self-synthesizing transposable element called Polinton or Maverick, which is present ...
*  Genome
The Alu element is the most common SINE found in primates. It is about 350 base pairs and occupies about 11% of the human ... Non-long terminal repeats (Non-LTRs) are classified as long interspersed elements (LINEs), short interspersed elements (SINEs ... and Penelope-like elements. In Dictyostelium discoideum, there is another DIRS-like elements belong to Non-LTRs. Non-LTRs are ... Transposable elements (TEs) are sequences of DNA with a defined structure that are able to change their location in the genome ...
*  Evolution of biological complexity
Daniel, Chammiran; Behm, Mikaela; Öhman, Marie (2015). "The role of Alu elements in the cis-regulation of RNA processing". ...
*  BC200 lncRNA
The 5' region of the RNA defines one domain and consists of Alu repeat elements. The other two structural domains are a central ... "BRAIN CYTOPLASMIC RNA 1; BCYRN1." "Alu elements: know the SINEs" "The Long Non-Coding RNA BC200 (BCYRN1) Is Critical for Cancer ... The 5' region of monomeric Alu short interspersed repetitive elements (SINEs) allows for BC200 RNA transposition and has been ... a Neural RNA Polymerase III Product Encoded by a Monomeric Alu Element". Proceedings of the National Academy of Sciences of the ...
*  Short interspersed nuclear element
Alu elements are the most common SINE in humans, with >1,000,000 copies throughout the genome. Alu element copy number ... Insertion of Alu elements in the human genome is associated with breast cancer, colon cancer, leukemia, hemophilia, Dent's ... Short Interspersed Nuclear Elements (SINEs) are non-autonomous, non-coding transposable elements (TEs) that are 50-500 base ... The transposition and recombination of SINEs and other active nuclear elements is thought to be one of the major contributions ...
*  Proopiomelanocortin
Kuehnen P, Mischke M, Wiegand S, Sers C, Horsthemke B, Lau S, Keil T, Lee YA, Grueters A, Krude H (2012). "An Alu element- ...
*  Gene polymorphism
Alu which is a repetitive element from Alu family, can trigger a polymorphism in human genome. Alu element is defined as a ... Alu element also has a role in RNA polymerase III for its compression of a RNA promoter. It has been found that Alu is repeated ... Insertion and repetitive of Alu element in human genome can cause mutations and disorders that are related to carcinogenesis. ... polymorphic repetitive elements and microsatellite variation. SNPs are a single nucleotide changes that happen in the genome in ...
*  C1-inhibitor
"Complete nucleotide sequence of the gene for human C1 inhibitor with an unusually high density of Alu elements". European ... "Complete nucleotide sequence of the gene for human C1 inhibitor with an unusually high density of Alu elements". European ... Stoppa-Lyonnet D, Carter PE, Meo T, Tosi M (February 1990). "Clusters of intragenic Alu repeats predispose the human C1 ...
*  Amplicon
The loci of Alu element insertion is selected, amplified and evaluated in terms of size of the fragment. The sex assay utilizes ... "Mobile element-based assay for human gender determination". Analytical Biochemistry. 312 (1): 77-9. doi:10.1016/S0003-2697(02) ...
*  Haplogroup DE
Hammer MF (September 1994). "A recent insertion of an alu element on the Y chromosome is a useful marker for human population ... The mutation was caused when a strand of DNA, known as Alu, inserted a copy of itself into the Y chromosome. Hence, all Y ... The most well-known unique event polymorphism (UEP) that defines DE is the Y-chromosome Alu Polymorphism (YAP) YAP. ...
*  ChIA-PET
Polak & Domany, (2006). Alu elements contain many binding sites for transcription factors and may play a role in regulation of ... Maston et al., (2006). Transcriptional Regulatory Elements in the Human Genome. Annu. Rev: Genomics. Hum Genet. (7); 29-59. ... Figure 7. Proposed mechanism showing how distal regulatory elements can initiate long-range chromatin interactions involving ... insulators and boundary elements, and transcription-factor binding sites (TFBS). Uncovering the interplay between regulatory ...
*  BCL2L13
Nonetheless, it still performs proapoptotic activity, mediated by the encoded Alu element, though the exact mechanisms remain ... completely lacking the BH domains 1 through 3 due to an in-frame stop codon inserted by an Alu element. Without the TM domain, ... a special splicing variant with an insertion of an Alu-like cassette, promotes etoposide- and Taxol-induced cell death". FEBS ...
*  Epigenetics of diabetes Type 2
Alu elements are known to create genomic instability and affect gene expression, and have been implicated in numerous human ... show that methylation levels at all four CpG sites displayed an increase in Alu methylation. This study provides the first ... Within this 7.7 kb, haplotype-specific methylation area, a highly conserved non-coding element (HCNE) was found. Anja Ragvin, a ... Epigenetic alterations arising during the lifetime of monozygotic twins in Alu repeats resulted in an increase in genomic s ...
*  Genome survey sequence
There are about 300 to 500 thousand copies of Alu repetitive element in human genome, which means one Alu element exists in 4 ... Alu element can be used for genome fingerprinting based on PCR, which is also called Alu PCR. There are several ways to analyze ... Alu repetitive element is member of Short Interspersed Elements (SINE) in mammalian genome. ... that is why it is called Alu repetitive element. By using special Alu sequence as target locus, specific human DNA can be ...
*  Pseudogene
link) Jurka J (December 2004). "Evolutionary impact of human Alu repetitive elements". Current Opinion in Genetics & ... This sort of competition for regulatory elements by RNAs that are endogenous to the genome has given rise to the term ceRNA. ... For example, somewhere between 30-44% of the human genome consists of repetitive elements such as SINEs and LINEs (see ... Those piRNAs regulate genes via the piRNA pathway in mammalian testes and are crucial for limiting transposable element damage ...
*  Dicer
A form of RNA called Alu RNA (the RNA transcripts of alu elements)) was found to be elevated in patients with insufficient ... However, with insufficient Dicer levels, the accumulation of alu RNA leads to the degeneration of RPE as a result of ... "DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88". Cell. 149 (4): 847-59. ...
*  ADAR
Alu elements and long interspersed nuclear element (LINEs). Mutations in this gene have been associated with dyschromatosis ... It has been suggested that ADAR1 is downregulated by cAMP- response element binding protein (CREB), limiting its ability to act ...
*  Retrotransposon
The most common SINE in primates is Alu. Alu elements are approximately 350 base pairs long, do not contain any coding ... Alu and B1 elements, with their 1.1 million and 650,000 copies in the human and mouse genomes, respectively, harbor a 7SL ... Alu and B1 elements, with their 1.1 million and 650,000 copies in the human and mouse genomes, respectively, harbor a 7SL ... Long INterspersed Elements (LINE) are a group of genetic elements that are found in large numbers in eukaryotic genomes, ...
*  Jürgen Brosius
... one example being the bewildering spectrum of tasks allocated to the evolutionarily young primate-specific Alu elements. Such ... He observed analogous trends in the field of repetitive or transposed genomic elements (TEs) including retroposed elements. ... These elements were initially considered to be junk, littering genomes, and proposed by only a few to constitute raw material ... doi: 10.1111/j.1749-6632.2009.05004.x Krull M, Brosius J, Schmitz J. Alu-SINE exonization: en route to protein-coding function ...
*  Human evolutionary genetics
Alu elements diverge quickly due to their high frequency of CpG dinucleotides which mutate roughly 10 times more often than the ... This is further supported by Alu-like short interspersed nuclear elements (SINEs) which have been found only in members of the ... "Retroposed elements as archives for the evolutionary history of placental mammals". PLoS Biol. 4 (4): e91. doi:10.1371/journal. ...
*  PDP-8
Using a one-bit serial arithmetic logic unit (ALU) allowed the PDP-8/S to be smaller and less expensive, although slower than ... For faster math, a customer could buy the "extended arithmetic element" (EAE) that provided multiply and divide instructions ... Extended Arithmetic Element Type 182, PDP-8 User's Handbook, Digital Equipment Corporation, 1966; p. 41. Chapter 4: System ...
*  Circular RNA
Alu elements that could form IRAlus, either convergent or divergent, are juxtaposed across flanking introns of circRNAs in a ... Alu is the most common transposon in the genome. By the Alu repeats base pairing to one another, it has been proposed that this ... CiRNA formation, rather than being a random process, seems to depend on the presence of specific elements near the 5' splice ... Compared to regions not resulting in circles, these introns are much more likely to contain complementary inverted Alu repeats ...