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*  Alpha-1 antitrypsin
"Gene regulation of the serine proteinase inhibitors alpha1-antitrypsin and alpha1-antichymotrypsin". Biochemical Society ... Recombinant alpha-1 antitrypsin is not yet available for use as a drug but is under investigation as a therapy for alpha-1 ... Alpha-1-antitrypsin or α1-antitrypsin (A1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in ... The alpha region can be further divided into two sub-regions, termed "1" and "2". Alpha-1 antitrypsin is the main protein of ...
*  Alpha 1-antichymotrypsin
... (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin ... Alpha 1-antichymotrypsin inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in ... Alpha-1 antitrypsin, another serpin that is analogous for protecting the body from excessive effects of its own inflammatory ... Alpha 1-antichymotrypsin is also associated with the pathogenesis of Alzheimer's disease as it enhances the formation of ...
*  DNAJC1
2006). "BIP co-chaperone MTJ1/ERDJ1 interacts with inter-alpha-trypsin inhibitor heavy chain 4". Biochem. Biophys. Res. Commun ... DNAJC1 has been shown to interact with Alpha 1-antichymotrypsin. GRCh38: Ensembl release 89: ENSG00000136770 - Ensembl, May ... 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. Kroczynska B, Evangelista CM, Samant SS, et al. (2004). "The SANT2 domain of ... 83 (1): 153-67. doi:10.1016/S0888-7543(03)00235-0. PMID 14667819. Strausberg RL, Feingold EA, Grouse LH, et al. (2003). " ...
*  CMA1
Mellon MB, Frank BT, Fang KC (2002). "Mast cell alpha-chymase reduces IgE recognition of birch pollen profilin by cleaving ... Caughey GH, Raymond WW, Wolters PJ (2000). "Angiotensin II generation by mast cell alpha- and beta-chymases". Biochim. Biophys ... 1993). "Reaction of human chymase with reactive site variants of alpha 1-antichymotrypsin. Modulation of inhibitor versus ... 286 (1): 163-73. doi:10.1006/jmbi.1998.2462. PMID 9931257. Pereira PJ, Wang ZM, Rubin H, et al. (1999). "The 2.2 A Crystal ...
*  DNA polymerase alpha catalytic subunit
Tsuda M, Masuyama M, Katsunuma T (1986). "Inhibition of human DNA polymerase alpha by alpha 1-antichymotrypsin". Cancer Res. 46 ... DNA polymerase alpha catalytic subunit is an enzyme that in humans is encoded by the POLA1 gene. Pol α has limited processivity ... DNA dependent polymerase alpha (Pol α) has been shown to interact with Retinoblastoma protein, PARP1 and RBMS1. DNA Polymerase ... Wong SW, Wahl AF, Yuan PM, Arai N, Pearson BE, Arai K, Korn D, Hunkapiller MW, Wang TS (1988). "Human DNA polymerase alpha gene ...
*  MST1
Skeel A, Leonard EJ (2001). "alpha 1-Antichymotrypsin is the human plasma inhibitor of macrophage ectoenzymes that cleave pro- ... 1999). "Characterization of free alpha- and beta-chains of recombinant macrophage-stimulating protein". Arch. Biochem. Biophys ... 138 (1-2): 171-4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. Waltz SE, Gould FK, Air EL, et al. (1996). "Hepatocyte ... 200 (1-2): 149-56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. Yoshikawa W, Hara H, Takehara T, et al. ( ...
*  Protein C inhibitor
The genetic code of protein C inhibitor is similar to alpha 1-antitrypsin and alpha 1-antichymotrypsin. The in vivo half time ... Hayashi S, Wakizaka A (July 1995). "Urinary protein C inhibitor binding region in the A alpha-chain of human fibrinogen". Blood ... Billingsley GD, Walter MA, Hammond GL, Cox DW (February 1993). "Physical mapping of four serpin genes: alpha 1-antitrypsin, ... alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome ...
*  Prostate-specific antigen
PSA exists in serum in the free (unbound) form and in a complex with alpha 1-antichymotrypsin; research has been conducted to ... ISBN 1-891276-02-6. [dead link] Catalona WJ, Richie JP, Ahmann FR, Hudson MA, Scardino PT, Flanigan RC, deKernion JB, Ratliff ... 154 (2 Pt 1): 407-13. doi:10.1016/S0022-5347(01)67064-2. PMID 7541857. Crawford ED, Schutz MJ, Clejan S, Drago J, Resnick MI, ... 148 (1): 83-6. PMID 1377290. Collins GN, Martin PJ, Wynn-Davies A, Brooman PJ, O'Reilly PH (May 1997). "The effect of digital ...
*  Chymotrypsin-C
1996). "Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced ... Brecher AS, Yang MP (1998). "Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity". J. Investig. Med. 46 (4 ... 195 (1-2): 27-39. doi:10.1016/0009-8981(90)90191-T. PMID 2093478. Masson E, Chen JM, Scotet V, et al. (2008). "Association of ... 123 (1): 83-91. doi:10.1007/s00439-007-0459-3. PMID 18172691. Rosendahl J, Witt H, Szmola R, et al. (2008). "Chymotrypsin C ( ...
*  Platelet-activating factor
"Synthesis and release of platelet-activating factor is inhibited by plasma alpha 1-proteinase inhibitor or alpha 1- ... antichymotrypsin and is stimulated by proteinases". The Journal of Experimental Medicine. 168 (4): 1293-306. doi:10.1084/jem. ... If the sn-1 was removed then PAF lacked any sort of biological activity. Finally, the sn-3 position of PAF was experimented ... 10 (1): 1-6. doi:10.1385/ENDO:10:1:1. PMID 10403564. Yaras N, Ugur M, Ozdemir S, Gurdal H, Purali N, Lacampagne A, Vassort G, ...
*  List of MeSH codes (D12.776)
... alpha-crystallin a chain MeSH D12.776.306.366.100.300 - alpha-crystallin b chain MeSH D12.776.306.366.300.100 - beta-crystallin ... steroid 12-alpha-hydroxylase MeSH D12.776.422.220.453.915.737 - steroid 16-alpha-hydroxylase MeSH D12.776.422.220.453.915.748 ... Retinoid X receptor alpha MeSH D12.776.826.701.500.625 - Retinoid X receptor beta MeSH D12.776.826.701.500.750 - Retinoid X ... interferon-alpha MeSH D12.776.467.750.500.250.100 - interferon alfa-2a MeSH D12.776.467.750.500.250.150 - interferon alfa-2b ...
*  List of MeSH codes (D12.776.124)
... alpha-macroglobulins MeSH D12.776.124.790.720.100.500 -- pregnancy-associated alpha 2-macroglobulins. ... immunoglobulin alpha-chains MeSH D12.776.124.486.485.114.619.251 -- immunoglobulin d MeSH D12.776.124.486.485.114.619.251.500 ... immunoglobulin alpha-chains MeSH D12.776.124.486.485.705.500.360 -- immunoglobulin delta-chains MeSH D12.776.124.486.485.705. ... alpha-macroglobulins MeSH D12.776.124.790.106.118 -- antiplasmin MeSH D12.776.124.790.106.125 -- antithrombin iii MeSH D12.776. ...
*  Antithrombin
Turk B, Brieditis I, Bock SC, Olson ST, Björk I (1997). "The oligosaccharide side chain on Asn-135 of alpha-antithrombin, ... alpha 1-antichymotrypsin and MENT. The conformational change most relevant for Factor IXa and Xa inhibition involves the P14 ... alpha 2-antiplasmin and Heparin cofactor II. The physiological target proteases of antithrombin are those of the contact ... 7 (1): 27-35. doi:10.1111/j.1365-2362.1977.tb01566.x. PMID 65284. Conard J, Brosstad F, Lie Larsen M, Samama M, Abildgaard U ( ...
*  Protease
It includes alpha 1-antitrypsin (which protects the body from excessive effects its own inflammatory proteases), alpha 1- ... antichymotrypsin (which does likewise), C1-inhibitor (which protects the body from excessive protease-triggered activation of ... 568: 1-5. Woessner, edited by Alan J. Barrett, Neil D. Rawlings, J. Fred (2004). Handbook of proteolytic enzymes (2nd ed.). ... 151 (1): 13-25. doi:10.1093/jb/mvr129. PMID 22016395. N D Rawlings and A J Barrett (1993). "Evolutionary families of peptidases ...
*  Outline of immunology
Obligate heterodimers of one alpha and one beta subunits Alpha subunits A1 A2 A3 A4 A5 A6 A7 A8 A9 A10 A11 AD AE AL (CD11a) AM ... Alpha-v beta-3 Alpha-v beta-5 Immunoglobulin superfamily CAMs SynCAMs - Synaptic cell adhesion molecules NCAMs - Neural cell ... Fc-alpha receptors (FcαR) FcαRI (CD89, FCAR) Fcα/μR Fc-epsilon receptors (FcεR) FcεRI - Tetramer: FCER1A / FCER1B / two FCER1G ... Alpha 1-antichymotrypsin Alpha 1-antitrypsin Alpha 2-macroglobulin C-reactive protein Ceruloplasmin C3 Ferritin Fibrin ...
*  KLK6
Iwata A, Maruyama M, Akagi T, Hashikawa T, Kanazawa I, Tsuji S, Nukina N (Oct 2003). "Alpha-synuclein degradation by serine ... antichymotrypsin". Clinical Chemistry. 49 (5): 746-51. doi:10.1373/49.5.746. PMID 12709365. Magklara A, Mellati AA, Wasney GA, ... "Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)- ... 1350 (1): 11-4. doi:10.1016/s0167-4781(96)00187-x. PMID 9003450. Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis ...
*  Serpin
alpha 1-antitrypsin Pittsburgh (358 Met leads to Arg), a fatal bleeding disorder". The New England Journal of Medicine. 309 (12 ... The X-ray crystal structures of antithrombin, heparin cofactor II, MENT and murine antichymotrypsin reveal that these serpins ... Lomas DA, Evans DL, Finch JT, Carrell RW (June 1992). "The mechanism of Z alpha 1-antitrypsin accumulation in the liver". ... Initial research focused on their role in human disease: alpha 1-antitrypsin deficiency is one of the most common genetic ...
*  Alpha globulin
The alpha globulins typically have molecular weights of around 93 kDa. α1-antitrypsin Alpha 1-antichymotrypsin Orosomucoid ( ... Haptoglobin Alpha-2u globulin α2-macroglobulin Ceruloplasmin Thyroxine-binding globulin Alpha 2-antiplasmin Protein C Alpha 2- ... Alpha globulins are a group of globular proteins in plasma that are highly mobile in alkaline or electrically charged solutions ... lipoprotein Angiotensinogen Alpha-Globulins at the US National Library of Medicine Medical Subject Headings (MeSH). ...
*  Serum protein electrophoresis
... resulting in a typical elevation in the alpha-2 zone during inflammation. A normal alpha-2 and an elevated alpha-1 zone is a ... Alpha-2 macroglobulin may be elevated in children and the elderly. This is seen as a sharp front to the alpha-2 band. AMG is ... Stevenson, FT; Greene, S; Kaysen, GA (January 1998). "Serum alpha 2-macroglobulin and alpha 1-inhibitor 3 concentrations are ... Alpha-1 antitrypsin has an SG group and thiol compounds may be bound to the protein altering their mobility. A decreased band ...