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*  Graft-versus-tumor effect
... appears after allogeneic hematopoietic stem cell transplantation (HSCT). The graft contains donor T cells (T lymphocytes) that ... particularly in T-cell-depleted HLA-haploidentical HSCT. Graft-versus-host disease Hematopoietic stem cell transplantation ... 2005). "Graft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning". J ... host disease in allogeneic hematopoietic cell transplantation". J Autoimmun. 30 (3): 172-9. doi:10.1016/j.jaut.2007.12.002. PMC ...
*  Evans syndrome
The only prospect for a permanent cure is the high-risk option of an allogeneic hematopoietic stem cell transplantation (SCT). ... Oyama Y, Papadopoulos EB, Miranda M, Traynor AE, Burt RK (2001). "Allogeneic stem cell transplantation for Evans syndrome". ... Martino R, Sureda A, Brunet S (1997). "Peripheral blood stem cell mobilization in refractory autoimmune Evans syndrome: a ... Autoimmune hemolytic anemia is a condition in which the red blood cells that normally carry oxygen and carbon dioxide are ...
*  Extramedullary hematopoiesis
"Pulmonary extramedullary hematopoiesis in patients with myelofibrosis undergoing allogeneic stem cell transplantation. Can ... For example, it can be caused by myelofibrosis, after fibrotic changes within the bone marrow "crowd out" hematopoietic cells, ...
*  Waldenström's macroglobulinemia
Allogeneic stem cell transplantation can induce durable remissions for heavily pre-treated patients. As of October 2010, there ... "Allogeneic Stem-Cell Transplantation in Patients with Waldenstrom Macroglobulinemia: Report from the Lymphoma Working Party of ... Yang L, Wen B, Li H, Yang M, Jin Y, Yang S, Tao J (1999). "Autologous peripheral blood stem cell transplantation for ... lymphoplasmacytoid cells and plasma cells. Both cell types are white blood cells. WM is characterized by having high levels of ...
*  Transmission-based precautions
Adenovirus infection in children after allogeneic stem cell transplantation: diagnosis, treatment and immunity. Bone Marrow ... Transplantation 2001;71(1):59-64 Boyce JM. MRSA patients: proven methods to treat colonization and infection. J Hosp Infect ... J Pediatr 2005;146(4):523-7. Wood DJ, David TJ, Chrystie IL, Totterdell B. Chronic enteric virus infection in two T-cell ... Transplantation 2001;71(1):59-64. CDC. Recommended antimicrobial agents for the treatment and postexposure prophylaxis of ...
*  Refractory cytopenia with multilineage dysplasia
Warlick ED, Cioc A, Defor T, Dolan M, Weisdorf D (January 2009). "Allogeneic stem cell transplantation for adults with ... Hamdi W, Ogawara H, Handa H, Tsukamoto N, Nojima Y, Murakami H (November 2008). "Clinical significance of regulatory T cells in ...
*  FLAG (chemotherapy)
March 2012). "Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or ... June 2011). "Successful allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia during respiratory ... and ATG for allogeneic stem cell transplantation in elderly patients with relapsed or high-risk acute myeloid leukemia". Annals ... high-dose cytarabine and 12 Gy total body irradiation followed by allogeneic hematopoietic stem cell transplantation is ...
*  Myelofibrosis
The one known curative treatment is allogeneic stem cell transplantation, but this approach involves significant risks. Other ... which is a reduction in the number of all blood cell types: red blood cells, white blood cells, and platelets. Red blood cells ... JAK2 mutations are significant because JAK2 plays a role in controlling production of blood cells from hematopoietic stem cells ... Normally, mature red blood cells in adults do not have a cell nucleus, and the presence of nucleated red blood cells suggests ...
*  Progressive multifocal leukoencephalopathy
July 2002). "Nonmyeloablative allogeneic stem cell transplantation for refractory Hodgkin's lymphoma complicated by interleukin ... A number of drugs work against JC virus in cell culture, but there is no proven, effective therapy in humans. For example, 1-O- ... PML is a demyelinating disease, in which the myelin sheath covering the axons of nerve cells is gradually destroyed, impairing ...
*  Fusariosis
... of disseminated cutaneous fusariosis with liposomal amphotericin B and terbinafine after allogeneic stem cell transplantation ...
*  Hematopoietic stem cell transplantation
It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from ... Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived ... Mortality for allogeneic stem cell transplantation can be estimated using the prediction model created by Sorror et al., using ... Infection and graft-versus-host disease are major complications of allogeneic HSCT. Hematopoietic stem cell transplantation ...
*  DDX3Y
"Minor histocompatibility antigen DBY elicits a coordinated B and T cell response after allogeneic stem cell transplantation". J ... rescues a hamster temperature-sensitive ET24 mutant cell line with a DDX3X mutation". Exp. Cell Res. 300 (1): 213-22. doi: ... Cells. 12 (2): 209-14. PMID 11710523. Vogt MH, van den Muijsenberg JW, Goulmy E, et al. (2002). "The DBY gene codes for an HLA- ... 2005). "The AZFa gene DBY (DDX3Y) is widely transcribed but the protein is limited to the male germ cells by translation ...
*  SigmaXL
"Increased frequencies of CD4+CD25high Tregs correlate with disease relapse after allogeneic stem cell transplantation for ...
*  Steven Z. Pavletic
Pavletic's research also includes pioneering work on the use of peripheral blood cells in allogeneic stem cell transplantation ... From 1999 until 2002 he was the Director of the Allogeneic Stem Cell Transplantation program at the University of Nebraska. ... the most common late effect in cancer survivors who underwent allogeneic stem cell transplantations as a form of treatment. ... of a multidisciplinary center for the treatment of chronic GVHD resulting from allogeneic stem cell transplantations. In 2013 ...
*  CD135
... sustained regression before and after allogeneic stem cell transplantation". Blood. 113 (26): 6567-71. doi:10.1182/blood-2009- ... Signalling of FLT3 is important for the normal development of haematopoietic stem cells and progenitor cells. The FLT3 gene is ... CD135 is important for lymphocyte (B cell and T cell) development, but not for the development of other blood cells (myeloid ... Stem Cells. 24 (5): 1174-84. doi:10.1634/stemcells.2005-0519. PMID 16410383. Stubbs MC, Armstrong SA (2007). "FLT3 as a ...
*  Graft-versus-host disease
... treatment of refractory oral chronic graft-versus-host disease following allogeneic stem cell transplantation". Bone Marrow ... Prior to haematopoietic stem cell transplantation, radiation or chemotherapy results in damage and activation of host tissues, ... The T-cells of umbilical cord blood (UCB) have an inherent immunological immaturity, and the use of UCB stem cells in unrelated ... cells in the graft itself that causes it but cells in the graft that make the recipient's T cells act like donor T cells. It ...
*  Gemtuzumab ozogamicin
... increases the risk of veno-occlusive disease in patients who undergo myeloablative allogeneic stem cell transplantation". Blood ... therapy is associated with hepatic venoocclusive disease in patients who have not received stem cell transplantation". Cancer. ... CD33 is expressed in most leukemic blast cells but also in normal hematopoietic cells, the intensity diminishing with ... maturation of stem cells. Common side effects of administration included shivering, fever, nausea and vomiting. Serious side ...
*  Chronic lymphocytic leukemia
... forms of allogeneic stem cell transplantation, a high-risk treatment using blood cells from a healthy donor, may be curative, ... Younger individuals, if at high risk for dying from CLL, may consider allogeneic hematopoietic stem cell transplantation (HSCT ... An intermediate level, called reduced-intensity conditioning allogeneic stem cell transplantation, may be better tolerated by ... Autologous stem cell transplantation, using the recipient's own cells, is not curative. ...
*  Follicular lymphoma
Although allogeneic stem cell transplantation may be curative, the mortality from the procedure is too high to be a first line ... and allogeneic (donor) hematopoietic stem cell transplantation. Follicular lymphoma is regarded as incurable, unless the ... cell-cell interactions in immune niches, and the production and class-switching of immunoglobulins. MiRNAs influence B cell ... "large cells". These follicles are surrounded by non-malignant cells, mostly T-cells. In the follicles, centrocytes typically ...
*  AMELX
"Establishing the method of chimerism monitoring after allogeneic stem cell transplantation using multiplex polymerase chain ... Cells, Tissues, Organs. 189 (1-4): 203-6. doi:10.1159/000151376. PMC 2824197 . PMID 18701806. Lee SK, Seymen F, Kang HY, Lee KE ... brain and cells of the hematopoietic system". European Journal of Oral Sciences. 114 Suppl 1: 183-9; discussion 201-2, 381. doi ... Cells, Tissues, Organs. 189 (1-4): 224-9. doi:10.1159/000151378. PMC 2754863 . PMID 18714142. Richard B, Delgado S, Gorry P, ...
*  Leukocyte adhesion deficiency
"Allogeneic hematopoietic stem cell transplantation for Leukocyte Adhesion Deficiency". Pediatrics. 123 (3): 836-840. doi: ... A 2009 study reported results from 36 children who had received a stem cell transplant. At the time of follow-up (median time ... the only current curative therapy is the hematopoietic stem cell transplant. However, progress has been made in gene therapy, ... Cell. 50 (2): 193-202. doi:10.1016/0092-8674(87)90215-7. PMID 3594570. van Vliet DN, Brandsma AE, Hartwig NG (2004). "Leukocyte ...
*  Epstein-Barr virus nuclear antigen 1
... specific t cells as treatment for EBV reactivation and lymphoproliferative disorders after allogeneic stem-cell transplantation ... This thereby inhibits the CD8-restricted cytotoxic T cell response against virus-infected cells. EBNA1 is expressed from the Qp ... Transgenic mice expressing EBNA1 in B cell lines showed a predisposition for developing B cell lymphoma, thus demonstrating ... Wilson, J.B.; J.L. Bell; A.J. Levine (1996). "Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in ...
*  ASCT
... ultrasound American Society for Cytotechnology Autologous stem cell transplantation Allogeneic stem cell transplantation. ...
*  Acute lymphoblastic leukemia
... subtype of ALL is frequently resistant to the combination of chemotherapy and TKIs and allogeneic stem cell transplantation is ... Stem cell transplantation may be used if the disease recurs following standard treatment. Additional treatments such as ... Hyperdiploid cells are defined as cells with more than 50 chromosomes, while hypodiploid is defined as cells with less than 44 ... The process as a whole results in an effector cell, typically a T-cell, that can recognize a tumor cell antigen in a manner ...
*  Minor histocompatibility antigen
... which allows for the destruction of harmful tumor cells. In mice, allogeneic stem cell transplantation donor CD8+ T cells ... The lack of recognition of a T cell to this self antigen is the reason why allogeneic stem cell transplantation for an HLA ... The consequences of an immune response are seen in allogeneic hematopoietic stem cell transplantation (HCT) when the peptides ... but is exposed to the HA-1 peptide during pregnancy or allogeneic stem cell transplantation. During pregnancy, the fetal HA-1 ...
*  Voriconazole
"Complications of hematopoietic stem transplantation: Fungal infections". Hematology/oncology and stem cell therapy. PMID ... including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ ... It works by affecting the cell membrane or affecting fungal metabolism. Voriconazole was approved for medical use in the United ... squamous cell skin cancer, and Stevens-Johnson syndrome; in long-term use there is a warning of the risk of bone fluorosis and ...
*  Embryonic stem cell
... there is a technical problem of graft-versus-host disease associated with allogeneic stem cell transplantation. However, these ... Embryonic stem cells (ES cells) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre ... Pluripotency distinguishes embryonic stem cells from adult stem cells found in adults; while embryonic stem cells can generate ... Embryoid body Embryonic Stem Cell Research Oversight Committees Fetal tissue implant Stem cell controversy Induced stem cells ...