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*  Graft-versus-tumor effect
... appears after allogeneic hematopoietic stem cell transplantation (HSCT). The graft contains donor T cells (T lymphocytes) that ... particularly in T-cell-depleted HLA-haploidentical HSCT. Graft-versus-host disease Hematopoietic stem cell transplantation ... 2005). "Graft-versus-tumor effects after allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning". J ... host disease in allogeneic hematopoietic cell transplantation". J Autoimmun. 30 (3): 172-9. doi:10.1016/j.jaut.2007.12.002. PMC ...
*  Leukocyte adhesion deficiency
"Allogeneic hematopoietic stem cell transplantation for Leukocyte Adhesion Deficiency". Pediatrics. 123 (3): 836-840. doi: ... the only current curative therapy is the hematopoietic stem cell transplant. However, progress has been made in gene therapy, ... A 2009 study reported results from 36 children who had received a stem cell transplant. At the time of follow-up (median time ... Cell. 50 (2): 193-202. doi:10.1016/0092-8674(87)90215-7. PMID 3594570. van Vliet DN, Brandsma AE, Hartwig NG (2004). "Leukocyte ...
*  Andrew Pecora
2003-11-15). "Comparison of autologous and allogeneic hematopoietic stem cell transplantation for follicular lymphoma". Blood. ... 1998). "CD34+CD33- cells influence days to engraftment and transfusion requirements in autologous blood stem-cell recipients". ... March 2000). "Therapeutic Relevance of CD34 Cell Dose in Blood Cell Transplantation for Cancer Therapy". Journal of Clinical ... to become assistant director of stem cell and bone marrow transplantation from 1990 to 1993. He went on to become the program's ...
*  Fanconi anemia
2013). "Allogeneic hematopoietic stem cell transplantation in Fanconi anemia: the EBMT experience". Blood. 122: 4279-4286. doi: ... A more permanent cure is hematopoietic stem cell transplantation. If no potential donors exist, a savior sibling can be ... although more recent published evidence suggests that earlier allogeneic hematopoietic progenitor cell transplantation in ... unless prompt allogeneic hematopoietic progenitor cell transplant is an option). FA patients are at elevated risk for the ...
*  Olfactory ensheathing glia
Pessach, I.; Shimoni, A.; Nagler, A. (2012). "Apoptotic cells in allogeneic hematopoietic stem cell transplantations: "turning ... Apoptotic cells have been administered simultaneously with hematopoietic stem cells in experimental transplantation models, in ... Researchers suggest that these cells possess a unique ability to remyelinate injured neurons. Stem cell transplantation has ... as cell survival is usually less than 1% after transplantation. The inability of these cells to sustain after transplantation ...
*  Myeloid sarcoma
Allogeneic hematopoietic stem cell transplantation should be considered in fit patients with suitable available donor, as long ... July 2008). "Allogeneic Hematopoietic Stem-Cell Transplantation for Myeloid Sarcoma: A Retrospective Study From the SFGM-TC". J ... those whose myeloblasts express T-cell surface markers, CD13, or CD14 those with high peripheral white blood cell counts ... Meningeal leukemia, or invasion of the subarachnoid space by leukemic cells, is usually considered distinct from chloroma, ...
*  FLAG (chemotherapy)
June 2011). "Successful allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia during respiratory ... high-dose cytarabine and 12 Gy total body irradiation followed by allogeneic hematopoietic stem cell transplantation is ... and cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients ... March 2012). "Upfront allogeneic blood stem cell transplantation for patients with high-risk myelodysplastic syndrome or ...
*  Marcel R.M. van den Brink
"Adoptive transfer of T-cell precursors enhances T-cell reconstitution after allogeneic hematopoietic stem cell transplantation ... "Nrf2 regulates haematopoietic stem cell function". Nature Cell Biology. 2013; 15(3): 309-16. PMID 23434824; PMC 3699879. Hanash ... is a Dutch hematologist and researcher who is an expert in hematopoietic stem cell transplantation for cancer patients. He is ... "Two Memorial Sloan Kettering Studies Focus on Role of Antibiotics in Stem Cell Transplantation", On Cancer, News and Insights ...
*  Addressin
... impact of MADCAM1 gene single nucleotide polymorphisms to the outcome of allogeneic hematopoietic stem cell transplantation". ... 2005). "Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells". Am. J. Physiol., Cell ... MADCAM is selectively expressed on mucosal endothelial cells, driving memory T-cell re-circulation through mucosal tissues. In ... Addressin also known as mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) is a protein that in humans is encoded ...
*  Evans syndrome
The only prospect for a permanent cure is the high-risk option of an allogeneic hematopoietic stem cell transplantation (SCT). ... Oyama Y, Papadopoulos EB, Miranda M, Traynor AE, Burt RK (2001). "Allogeneic stem cell transplantation for Evans syndrome". ... Martino R, Sureda A, Brunet S (1997). "Peripheral blood stem cell mobilization in refractory autoimmune Evans syndrome: a ... Autoimmune hemolytic anemia is a condition in which the red blood cells that normally carry oxygen and carbon dioxide are ...
*  Chronic lymphocytic leukemia
... may consider allogeneic hematopoietic stem cell transplantation (HSCT). Myeloablative (bone marrow killing) forms of allogeneic ... An intermediate level, called reduced-intensity conditioning allogeneic stem cell transplantation, may be better tolerated by ... Autologous stem cell transplantation, using the recipient's own cells, is not curative. Younger individuals, if at high risk ... "Treatment-related mortality and graft-versus-leukemia activity after allogeneic stem cell transplantation for chronic ...
*  Cell therapy
Hwang WYK, Ong SY (2009). "Allogeneic haematopoietic stem cell transplantation without a matched sibling donor: Current options ... "The Impact of Market Volatility on the Cell Therapy Industry". Cell Stem Cell. 9 (5): 397-401. doi:10.1016/j.stem.2011.10.010. ... However, there are two main principles by which cells facilitate therapeutic action: Stem cell or progenitor cell engraftment, ... "Stem cell c-KIT and HOXB4 genes: Critical roles and mechanisms in self-renewal, proliferation and differentiation". Stem Cells ...
*  Dihydrolipoyl transacetylase
... of antibodies to PDC-E2 in patients with hematologic malignancies after allogeneic hematopoietic stem cell transplantation and ... The various parts of cellular respiration take place in different parts of the cell. In eukaryotes, glycolysis occurs in the ... "Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis". Hepatology. 36 (5): ... which can then be used to carry out numerous biological reactions within a cell. ...
*  Aplastic anemia
"First-line allogeneic hematopoietic stem cell transplantation of HLA-matched sibling donors compared with first-line ... Hematopoietic stem cell transplantation is also used, especially for patients under 30 years of age with a related matched ... Aplastic anemia is a rare disease in which the bone marrow and the hematopoietic stem cells that reside there are damaged. This ... The multipotent stem cells in the bone marrow reconstitute all three blood cell lines, giving the patient a new immune system, ...
*  General University Hospital of Patras
... a fully accredited Allogeneic Hematopoietic Stem Cell Transplantation Program has been established, which performs all types of ... stem cells harvested from genetically similar but not identical donors - and Autologous - stem cells harvested from self- HCTs ... In Greece, Hematopoietic Cell Transplantation (HCT) was first performed in 1985 and over 250 are now carried out every year. ... At the Bone Marrow Transplantation Unit of the University Hospital of Patras, ...
*  KIR3DL3
KIR and patient HLA genotypes on outcome following HLA-identical sibling allogeneic hematopoietic stem cell transplantation for ... Killer cell immunoglobulin-like receptor 3DL3 is a protein that in humans is encoded by the KIR3DL3 gene. Killer cell ... are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and ... "Inhibition of natural killer cell activation signals by killer cell immunoglobulin-like receptors (CD158)". Immunol Rev. 181: ...
*  Minor histocompatibility antigen
The consequences of an immune response are seen in allogeneic hematopoietic stem cell transplantation (HCT) when the peptides ... which allows for the destruction of harmful tumor cells. In mice, allogeneic stem cell transplantation donor CD8+ T cells ... The lack of recognition of a T cell to this self antigen is the reason why allogeneic stem cell transplantation for an HLA ... but is exposed to the HA-1 peptide during pregnancy or allogeneic stem cell transplantation. During pregnancy, the fetal HA-1 ...
*  Alemtuzumab
... severe steroid-resistant acute intestinal graft-versus-host disease after allogeneic hematopoietic stem cell transplantation ( ... It is also used in some conditioning regimens for bone marrow transplantation, kidney transplantation and islet cell ... October 1983). "Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human ... Alemtuzumab is a drug used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL) and T-cell ...
*  Treatment of cancer
Allogeneic hematopoietic stem cell transplantation ("bone marrow transplantation" from a genetically non-identical donor) can ... Most cells in the body grow and divide to form new cells. But cancer cells grow and divide faster than many of the normal cells ... This is known as autologous stem cell transplantation. Targeted therapy, which first became available in the late 1990s, has ... Although radiation damages both cancer cells and normal cells, most normal cells can recover from the effects of radiation and ...
*  Follicular lymphoma
... and allogeneic (donor) hematopoietic stem cell transplantation. Follicular lymphoma is regarded as incurable, unless the ... Although allogeneic stem cell transplantation may be curative, the mortality from the procedure is too high to be a first line ... cell-cell interactions in immune niches, and the production and class-switching of immunoglobulins. MiRNAs influence B cell ... "large cells". These follicles are surrounded by non-malignant cells, mostly T-cells. In the follicles, centrocytes typically ...
*  Cernunnos deficiency
... one finds that treatment with allogeneic HSCT(hematopoietic stem cell transplantation, which are stem cells that bring about ... "Bone Marrow (Hematopoietic) Stem Cells , stemcells.nih.gov". stemcells.nih.gov. Retrieved 2017-07-13. Sullivan, Kathleen E.; ... V(D)J recombination is a genetic recombination that happens in early stages of B and T cell maturation. The diagnosis of ... other cells) has proven useful in some instances. Additionally the following treatments are also used: Antibiotic treatment ...
*  Short course immune induction therapy
... of Epstein-Barr Virus Reactivation After Alemtuzumab-based Conditioning for Allogeneic Hematopoietic Stem-Cell Transplantation ... "Suppression of Allograft Rejection with Anti-αβ T Cell Receptor Antibody in Rat Corneal Transplantation?", Transplantation 27 ... T-cells are able to distinguish between self and non-self largely through their T-cell receptor, or TCR. Immune tolerance is ... "Induction of Long-Term Renal Allograft Survival By Pretransplant T Cell Receptor -αβ-Targeted Therapy", Transplantation 27 ...
*  GATA2
... and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation". Leuk Res Rep. 4 (2): 72-5. doi: ... including early erythroid cells, mast cells, and megakaryocytes, and also in nonhematopoietic embryonic stem cells. In chicken ... GATA3 expression is restricted to T-lymphocyte cells and some nonhematopoietic cell types, including embryonic stem cells. ... "Roles of hematopoietic transcription factors GATA-1 and GATA-2 in the development of red blood cell lineage". Acta Haematol. ...
*  Stem cell marker
... evaluation of procalcitonin in adults with non-neutropenic fever after allogeneic hematopoietic stem cell transplantation". ... Stem cell markers are genes and their protein products used by scientists to isolate and identify stem cells. Stem cells can ... 2005). "Somatic stem cell marker prominin-1/CD133 is expressed in embryonic stem cell-derived progenitors". Stem Cells. 23 (6 ... Hirao A, Arai F, Suda T (December 2004). "Regulation of cell cycle in hematopoietic stem cells by the niche". Cell Cycle. 3 (12 ...
*  Hematopoietic stem cell transplantation
Infection and graft-versus-host disease are major complications of allogeneic HSCT. Hematopoietic stem cell transplantation ... Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived ... It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from ... Mortality for allogeneic stem cell transplantation can be estimated using the prediction model created by Sorror et al., using ...
*  Voriconazole
"Complications of hematopoietic stem transplantation: Fungal infections". Hematology/oncology and stem cell therapy. PMID ... including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ ... It works by affecting the cell membrane or affecting fungal metabolism. Voriconazole was approved for medical use in the United ... squamous cell skin cancer, and Stevens-Johnson syndrome; in long-term use there is a warning of the risk of bone fluorosis and ...