Etidocaine
Alkylation with N-Ethylpropylamine [20193-20-8] (4) gives Etidocaine (5). Sisk AL (1992). "Long-acting local anesthetics in ...
Jin-Quan Yu
Bintang, Liu; Jinquan, Yu; Aiqun, Eng; Ping, Zhou; Shude, Xiao (1995-06-25). "Study on selective alkylation of guaiacol with ...
Trimethyldiborane
van Aalten, Lloyd; Seely, G. R.; Oliver, Juhn; Ritter, D. M. (1 June 1961). Kinetics and Equilibria in the Alkylation of ...
Butanilicaine
Alkylation with N-Butylamine (4) completed the synthesis of Butanilicaine (5). Haussler A, Ther L. [Chemical detection of ...
Wurtz-Fittig reaction
Typically the reaction is used for the alkylation of aryl halides; however, with the use of ultrasound the reaction can also be ...
Quelet reaction
Blanc reaction Electrophilic aromatic substitution Friedel-Crafts Alkylation Wang, Zerong (2009). "517: Quelet Reaction". ...
Photoredox catalysis
This transformation include alkylations with other classes of activated alkyl halides of synthetic interest. In particular, the ... In this approach for the α-alkylation of aldehydes, [Ru(bipy)3]2+ reductively fragments an activated alkyl halide, such as ... This type of mechanism is excluded for the photocatalytic alkylation reaction because whereas enamine radical cation was ... also investigated the productive merger of photoredox and organocatalytic methods to achieve enantioselective alkylation of ...
2-Pyridone
Beak P. (1977). "Energies and Alkylation of Tautomeric Heterocyclic-Compounds - Old Problems New Answers". Acc. Chem. Res. 10 ( ...
Hydrobromic acid
It also catalyzes alkylation reactions and the extraction of certain ores. Industrially significant organic compounds prepared ...
Methyldiborane
van Aalten, Lloyd; Seely, G. R.; Oliver, Juhn; Ritter, D. M. (1 June 1961). Kinetics and Equilibria in the Alkylation of ...
Epothilone
Ketone 2 was constructed via Enders alkylation starting from the hydrazone. Ozonolysis, the last step of the Enders alkylation ...
Kendrick mass
Members of an alkylation series have the same Kendrick mass defect. The Kendrick mass defect has also been defined as Kendrick ... Ions of the same family, for example the members of an alkylation series, have the same Kendrick mass defect but different ... The members of an alkylation series have the same degree of unsaturation and number of heteroatoms (nitrogen, oxygen and sulfur ...
Carbon nanotube chemistry
Alkylation−Reoxidation: A Functionalization Sequence for Single-Wall Carbon Nanotubes". Journal of the American Chemical ... "Preferred functionalization of metallic and small-diameter single walled carbon nanotubes via reductive alkylation". Journal of ...
Dicarbonyl
Also common are the 2-substituted derivatives with the formula RCH(CO2R)2, which arise by C-alkylation of the conjugate base ( ... They are often prepared by alkylation of the enolate of malondialdehyde. 1,3-Diketones are also called β-diketones. An ...
Hass-Bender oxidation
Bersohn, Malcolm (1961). "C versus O Alkylation in the Case of a Stable Cation". J. Am. Chem. Soc. 83 (9): 2136-2138. doi: ...
Dithiobenzoic acid
Its conjugate base, dithiobenzoate, undergoes S-alkylation to give dithiocarboxylate esters. Similarly, dithiobenzoate reacts ...
Trifluoroacetone
Similarly, alkylation with Grignard reagents provides a route to tertiary alcohols. Alkylation and arylation can be achieved ...
Quaternary ammonium cation
Quaternary ammonium compounds are prepared by the alkylation of tertiary amine. Industrial production of commodity quat salts ...
Phosphonium
... obtained by the alkylation of phosphorus trichloride: RCl + PCl3 + AlCl3 → [RPCl3]+AlCl− 4 The main industrial procedure for ... are produced by alkylation of organophosphines. For example, the reaction of triphenylphosphine with methyl bromide gives ...
Electrophilic substitution of unsaturated silanes
Nucleophilic catalysis of alkylation is rare, because protodesilylation tends to occur. Lewis acid activation is more commonly ...
Dapansutrile
OLT1177 is synthesized by alkylation of sodium methanesulfinate with 3-bromopropionitrile. This reaction produces crude ...
Acrolein
The main metabolic pathway for acrolein is the alkylation of glutathione. The WHO suggests a "tolerable oral acrolein intake" ...
David MacMillan
Examples include Diels-Alder reactions, 1,3-dipolar cycloadditions, Friedel-Crafts alkylations or Michael additions. MacMillan ... Crafts Alkylation". Journal of the American Chemical Society. American Chemical Society (ACS). 123 (18): 4370-4371. doi:10.1021 ... The Direct Asymmetric Alkylation of Aldehydes". Science. 322 (5898): 77-80. Bibcode:2008Sci...322...77N. doi:10.1126/science. ...
Bromocyclohexane
Le, Chip; Liang, Yufan; Evans, Ryan W.; Li, Ximing; MacMillan, David W. C. (2017). "Selective sp3 C-H alkylation via polarity- ...
Organolithium reagent
Although they are considered more reactive than Grignard reagents in alkylation, their use is still limited due to competing ... Most organolithium reagents used in alkylations are more stabilized, less basic, and less aggregated, such as heteroatom ... From Pinacolone to Selective C-Alkylations of Peptides. Difficulties and Opportunities Afforded by Complex Structures" (PDF). ... enolates are widely used as nucleophiles in carbon-carbon bond formation reactions such as aldol condensation and alkylation. ...
Asmic
Two sequential deprotonation-alkylation reactions and a subsequent sulfur-lithium exchange reaction allow the synthesis of tri- ... An Exceptional Building Block for Isocyanide Alkylations". Organic Letters. 20 (18): 5910-5913. doi:10.1021/acs.orglett.8b02574 ...
Dimethylaminopivalophenone
"Carbon-Carbon Alkylations with Amines and Ammonium Salts". Organic Reactions. 7 (3): 99-197. doi:10.1002/0471264180.or007.03. ...
Asymmetric ion-pairing catalysis
doi:10.1002/anie.201205449 Efficient catalytic asymmetric alkylations. 1. Enantioselective synthesis of (+)-indacrinone via ...
Andrée Marquet
A total synthesis of biotin based on the stereoselective alkylation of sulfoxides. J. Am. Chem. Soc., 1978, 100, 1558. 1961: ...
2-Chloroethanol
Several dyes are prepared by the alkylation of aniline derivatives with chloroethanol. It is also used for manufacture of ...