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*  Aldehyde oxidase 1
... is an enzyme that in humans is encoded by the AOX1 gene. Aldehyde oxidase produces hydrogen peroxide and, ... "Analysis of aldehyde oxidase and xanthine dehydrogenase/oxidase as possible candidate genes for autosomal recessive familial ... 2007). "Human aldehyde oxidase 1 interacts with ATP-binding cassette transporter-1 and modulates its activity in hepatocytes". ... Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. MOCOS GRCh38: Ensembl release 89: ENSG00000138356 - ...
*  Xanthine oxidase
... may result from a failure of the mechanism which inserts sulfur into the active sites of xanthine oxidase and aldehyde oxidase ... Because xanthine oxidase is a metabolic pathway for uric acid formation, the xanthine oxidase inhibitor allopurinol is used in ... H2O2 Xanthine oxidase can also act on certain other purines, pterins, and aldehydes. For example, it efficiently converts 1- ... explaining why xanthine oxidase is being researched for links to cardiovascular health. Both xanthine oxidase and xanthine ...
*  Aldehyde oxidase
... is very concentrated in the liver, where it oxidizes multiple aldehydes and nitrogenous heterocyclic compounds ... Aldehyde oxidase is a member of the molybd-flavo protein family and has a very complex evolutionary profile-as the genes of AO ... Aldehyde oxidase is thought to have a significant impact on pharmacokinetics. AO is capable of oxidizing many drugs in the ... Aldehyde oxidase (AO) is a metabolizing enzyme, located in the cytosolic compartment of tissues in many organisms. AO catalyzes ...
*  Aryl-aldehyde oxidase
In enzymology, an aryl-aldehyde oxidase (EC 1.2.3.9) is an enzyme that catalyzes the chemical reaction an aromatic aldehyde + ... JM; Sutherland, John B.; Pometto, Anthony L.; Miller, Jody M. (1982). "Production of an aromatic aldehyde oxidase by ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... The systematic name of this enzyme class is aryl-aldehyde:oxygen oxidoreductase. ...
*  Abscisic-aldehyde oxidase
In enzymology, an abscisic-aldehyde oxidase (EC 1.2.3.14) is an enzyme that catalyzes the chemical reaction abscisic aldehyde ... Seo M, Koiwai H, Akaba S, Komano T, Oritani T, Kamiya Y, Koshiba T (2000). "Abscisic aldehyde oxidase in leaves of Arabidopsis ... Sagi M, Fluhr R, Lips SH (1999). "Aldehyde oxidase and xanthine dehydrogenase in a flacca tomato mutant with deficient abscisic ... Koornneef M, Kamiya Y, Koshiba T (2000). "The Arabidopsis aldehyde oxidase 3 (AAO3) gene product catalyzes the final step in ...
*  Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain
Aldehyde oxidase (EC 1.2.3.1) catalyzes the conversion of an aldehyde in the presence of oxygen and water to an acid and ... The aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain is an evolutionary conserved protein domain. ... "Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas". Science. 270 (5239): 1170-6. doi: ... This activity is often found in a bifunctional enzyme with xanthine oxidase (EC 1.1.3.22) activity too. The enzyme can be ...
*  Alkanal monooxygenase (FMN-linked)
Hastings JW, Presswood RP (1978). "Bacterial luciferase: FMNH2-aldehyde oxidase". Methods Enzymol. Methods in Enzymology. 53: ... aldehyde monooxygenase, luciferase, and Vibrio fischeri luciferase. As of late 2007, 4 structures have been solved for this ... "Bacterial bioluminescence light emission in the mixed function oxidation of reduced flavin and fatty aldehyde". CRC. Crit. Rev ...
*  Ziprasidone
... is hepatically metabolized by aldehyde oxidase; minor metabolism occurs via cytochrome P450 3A4 (CYP3A4). ...
*  Isovanillin
It is a selective inhibitor of aldehyde oxidase. It is not a substrate of that enzyme, and is metabolized by aldehyde ... Isovanillin is a phenolic aldehyde, an organic compound and isomer of vanillin. ... Isovanillin and Protocatechuic Aldehyde with Freshly Prepared Guinea Pig Liver Slices". Cell Physiol Biochem. 15: 89-98. Uchida ...
*  Abscisic aldehyde
"Abscisic aldehyde oxidase in leaves of Arabidopsis thaliana". The Plant Journal. 23 (4): 481-488. doi:10.1046/j.1365-313x. ... Abscisic aldehyde is an intermediate in the biosynthesis of the plant hormone abscisic acid. It is produced by the ... Ram K. Sindhu, David H. Griffin and Daniel C. Walton (1990). "Abscisic Aldehyde Is an Intermediate in the Enzymatic Conversion ... "The Short-Chain Alcohol Dehydrogenase ABA2 Catalyzes the Conversion of Xanthoxin to Abscisic Aldehyde". The Plant Cell Online. ...
*  Lenvatinib
M2 and lenvatinib itself are oxidized by aldehyde oxidase (AO) to substances called M2' and M3', the main metabolites in the ... "Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase". Drug Metab Dispos. 42 (8): 1326-33. doi:10.1124/dmd. ...
*  Indole-3-acetaldehyde oxidase
T; Akaba, S; Oritani, T; Delarue, M; Bellini, C; Caboche, M; Koshiba, T (1998). "Higher activity of an aldehyde oxidase in the ... Marion-Poll A, Caboche M, Kamiya Y, Koshiba T (1998). "Molecular cloning and characterization of aldehyde oxidases in ... Some characteristics of the aldehyde oxidase of Avena coleoptiles". Physiol. Plant. 24 (2): 272-281. doi:10.1111/j.1399- ... Other names in common use include indoleacetaldehyde oxidase, IAAld oxidase, AO1, and indole-3-acetaldehyde:oxygen ...
*  Aldehyde dehydrogenase (FAD-independent)
Other names in common use include aldehyde oxidase, aldehyde oxidoreductase, Mop, and AORDd. As of late 2007, only one ... Fujishiro K, Aisaka K, Uwajima T (2003). "Purification and characterization of an aldehyde oxidase from Pseudomonas sp. KY 4690 ... "Crystal structure of the xanthine oxidase-related aldehyde oxido-reductase from D. gigas". Science. 270 (5239): 1170-6. doi: ... In enzymology, an aldehyde dehydrogenase (FAD-independent) (EC 1.2.99.7) is an enzyme that catalyzes the chemical reaction an ...
*  Molybdenum
... those enzymes include aldehyde oxidase, sulfite oxidase and xanthine oxidase. In some animals, and in humans, the oxidation of ... sulfite oxidase, xanthine oxidoreductase, aldehyde oxidase, and mitochondrial amidoxime reductase. People severely deficient in ... The activity of xanthine oxidase is directly proportional to the amount of molybdenum in the body. However, an extremely high ... The Relationship between Sulfite Oxidase and the Acute Toxicity of Bisulfite and SO2". Proceedings of the National Academy of ...
*  Molybdenum cofactor sulfurtransferase
"ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis ...
*  Allopurinol
1990). "Demonstration of a combined deficiency of xanthine oxidase and aldehyde oxidase in xanthinuric patients not forming ... but this action is principally carried out by aldehyde oxidase. The active metabolite of allopurinol is oxipurinol, which is ... and is an inhibitor of the enzyme xanthine oxidase. Xanthine oxidase is responsible for the successive oxidation of ... Allopurinol is in the xanthine oxidase inhibitor family of medications. Allopurinol was approved for medical use in the United ...
*  Molybdenum cofactor deficiency
... in molybdenum cofactor biosynthesis causes absence of enzyme activity of xanthine dehydrogenase/oxidase and aldehyde oxidase. ... Sulfite oxidase Reiss J, Johnson JL (June 2003). "Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and ... Usually this leads to death within months of birth, due to the lack of active sulfite oxidase. Furthermore, a mutational block ...
*  MOCOS
... sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH) and aldehyde oxidase (AOX1), which is required for ...
*  Betaine-aldehyde dehydrogenase
Other names in common use include betaine aldehyde oxidase, BADH, betaine aldehyde dehydrogenase, and BetB. This enzyme ... In enzymology, a betaine-aldehyde dehydrogenase (EC 1.2.1.8) is an enzyme that catalyzes the chemical reaction betaine aldehyde ... ROTHSCHILD HA, BARRON ES (1954). "The oxidation of betaine aldehyde by betaine aldehyde dehydrogenase". J. Biol. Chem. 209 (2 ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ ...
*  Zaleplon
... is primarily metabolised by aldehyde oxidase, and its half-life can be affected by substances which inhibit or induce ... aldehyde oxidase. Taken orally, zaleplon reaches full concentration in about one hour. It is extensively metabolised into 5- ...
*  Cyclic pyranopterin monophosphate
... xanthine dehydrogenase/oxidase and aldehyde oxidase. Günter Schwarz; José Angel Santamaria-Araujo; Stefan Wolf; Heon-Jin Lee; ... cPMP is a precursor to molybdenum cofactor, which is required for the enzyme activity of sulfite oxidase, ...
*  Retinal oxidase
Huang DY, Furukawa A, Ichikawa Y (1999). "Molecular cloning of retinal oxidase/aldehyde oxidase cDNAs from rabbit and mouse ... Mandal SK, Datta Chaudhuri B (1987). "Enzymic oxidation of vitamin A aldehyde to vitamin A acid by rat livers of experimental ... This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with ... In enzymology, a retinal oxidase (EC 1.2.3.11) is an enzyme that catalyzes the chemical reaction retinal + O2 + H2O ⇌ {\ ...
*  Molybdopterin
... aldehyde oxidase. Prosthetic group of: formate dehydrogenase, purine hydroxylase, thiosulfate reductase. Molybdenum cofactor ... Enzymes that contain the molybdopterin cofactor include xanthine oxidase, DMSO reductase, sulfite oxidase, and nitrate ... Molydopterin is a: Cofactor of: xanthine oxidase, DMSO reductase, sulfite oxidase, nitrate reductase, ethylbenzene ... In some enzymes, such as xanthine oxidase, the metal is bound to one molybdopterin, whereas, in other enzymes, e.g., DMSO ...
*  PCM1
... sulfite oxidase (mitochondrial precursor), aldehyde oxidase, erythropoietin receptor precursor and the ATPbinding cassette, sub ...
*  Xanthine dehydrogenase
aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain MOCOS xanthine oxidase GRCh38: Ensembl release 89: ... Corte ED, Stirpe F (Feb 1972). "The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of ... Rouquette M, Stevens C, Blake DR, Harrison R, Whish J, Whish WD (Aug 1997). "Expression of xanthine oxidase activity in human ... Minoshima S, Wang Y, Ichida K, Nishino T, Shimizu N (1994). "Mapping of the gene for human xanthine dehydrogenase (oxidase) ( ...
*  Metabolism
Carbohydrates are aldehydes or ketones, with many hydroxyl groups attached, that can exist as straight chains or rings. ... In humans, these include cytochrome P450 oxidases, UDP-glucuronosyltransferases, and glutathione S-transferases. This system of ...
*  List of EC numbers (EC 1)
... aldehyde oxidase EC 1.2.3.2: now *EC 1.1.3.22 EC 1.2.3.3: pyruvate oxidase EC 1.2.3.4: oxalate oxidase EC 1.2.3.5: glyoxylate ... pyridoxal oxidase EC 1.2.3.9: aryl-aldehyde oxidase EC 1.2.3.10: deleted EC 1.2.3.11: retinal oxidase EC 1.2.3.12: now *EC 1.14 ... D-aspartate oxidase EC 1.4.3.2: L-amino-acid oxidase EC 1.4.3.3: D-amino-acid oxidase EC 1.4.3.4: amine oxidase (flavin- ... glycine oxidase EC 1.4.3.20: L-lysine 6-oxidase EC 1.4.3.21: primary-amine oxidase EC 1.4.3.22: diamine oxidase EC 1.4.3.23: 7- ...