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*  Aspartate transaminase
Example reference ranges are shown below: Alanine transaminase (ALT/ALAT/SGPT) Transaminases PDB: 1AAM​Almo SC, Smith DL, ... Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as ... AST is similar to alanine transaminase (ALT) in that both enzymes are associated with liver parenchymal cells. The difference ... Aspartate transaminase, as with all transaminases, operates via dual substrate recognition; that is, it is able to recognize ...
*  Fatty liver
The serum alanine transaminase level usually is greater than the aspartate transaminase level in the nonalcoholic variant and ...
*  Liver disease
serum proteins, serum albumin, serum globulin, alanine transaminase, aspartate transaminase, prothrombin time, partial ...
*  Alanine transaminase
... (ALT) is a transaminase enzyme (EC 2.6.1.2). It is also called alanine aminotransferase (ALAT) and was ... Alanine transaminase shows a marked diurnal variation.[citation needed] The ratio of ALT to AST (aspartate aminotransferase) ... It catalyzes the two parts of the alanine cycle. Serum ALT level, serum AST (aspartate transaminase) level, and their ratio ( ... Red Cross Donor Requirements Clin Chem 2000;46:2027-2049 Alanine transaminase at the US National Library of Medicine Medical ...
*  Alanine-oxomalonate transaminase
Other names in common use include alanine-oxomalonate aminotransferase, L-alanine-ketomalonate transaminase, and alanine- ... In enzymology, an alanine-oxomalonate transaminase (EC 2.6.1.47) is an enzyme that catalyzes the chemical reaction L-alanine + ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... ketomalonate (mesoxalate) transaminase. It employs one cofactor, pyridoxal phosphate. Nagayama H, Muramatsu M, Shimura K (1958 ...
*  Alanine-glyoxylate transaminase
... alanine-glyoxylic aminotransferase, and L-alanine-glycine transaminase. This enzyme participates in alanine and aspartate ... In enzymology, an alanine-glyoxylate transaminase (EC 2.6.1.44) is an enzyme that catalyzes the chemical reaction L-alanine + ... The systematic name of this enzyme class is L-alanine:glyoxylate aminotransferase. Other names in common use include AGT, ... Noguchi T, Okuno E, Takada Y, Minatogawa Y, Okai K, Kido R (1978). "Characteristics of hepatic alanine-glyoxylate ...
*  Beta-alanine-pyruvate transaminase
Other names in common use include beta-alanine-pyruvate aminotransferase, and beta-alanine-alpha-alanine transaminase. This ... In enzymology, a beta-alanine-pyruvate transaminase (EC 2.6.1.18) is an enzyme that catalyzes the chemical reaction L-alanine ... the two substrates of this enzyme are L-alanine and 3-oxopropanoate, whereas its two products are pyruvate and beta-alanine. ... HAYAISHI O, NISHIZUKA Y, TATIBANA M, TAKESHITA M, KUNO S (1961). "Enzymatic studies on the metabolism of beta-alanine". J. Biol ...
*  Alanine-oxo-acid transaminase
Other names in common use include L-alanine-alpha-keto acid aminotransferase, leucine-alanine transaminase, alanine-keto acid ... In enzymology, an alanine-oxo-acid transaminase (EC 2.6.1.12) is an enzyme that catalyzes the chemical reaction L-alanine + a 2 ... Wilson DG, King KW, Burris RH (1954). "Transaminase reactions in plants" (PDF). J. Biol. Chem. 208 (2): 863-874. Molecular and ... ALTENBERN RA, HOUSEWRIGHT RD (1953). "Transaminases in smooth Brucella abortus, strain 19" (PDF). J. Biol. Chem. 204 (1): 159- ...
*  Pyruvic acid
Transamination by alanine transaminase produces alanine. Reduction by lactate dehydrogenase produces lactate. Pyruvate is sold ... It can also be used to construct the amino acid alanine and can be converted into ethanol or lactic acid via fermentation. ... to the amino acid alanine, and to ethanol. Therefore, it unites several key metabolic processes. In glycolysis, ...
*  Serine-pyruvate transaminase
Other names in common use include SPT, and hydroxypyruvate:L-alanine transaminase. This enzyme participates in glycine, serine ... In enzymology, a serine-pyruvate transaminase (EC 2.6.1.51) is an enzyme that catalyzes the chemical reaction L-serine + ... Sallach HJ (1956). "Formation of serine from hydroxypyruvate and L-alanine". J. Biol. Chem. 223: 1101-1108. Molecular and ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ...
*  Cefovecin
Mildly increased serum alanine transaminase (ALT) and gamma-glutamyltransferase may also occur. Other reported events in dogs ...
*  Ribociclib
16%). The drug also increases QT time and liver enzymes (alanine transaminase, aspartate transaminase). As ribociclib is mainly ...
*  Elevated transaminases
The two transaminases commonly measured are alanine transaminase (ALT) and aspartate transaminase (AST). These levels ... In medicine, the presence of elevated transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate ... Elevated transaminases that persist less than six months are termed 'acute' in nature, and those values that persist for six ... The liver has transaminases to synthesize and break down amino acids and to convert energy storage molecules. The ...
*  Dicarboxylic aminoaciduria
Below is an example of how glutamate is used to synthesize alanine via alanine transaminase. Glutamate + pyruvate ⇌ α- ... ketoglutarate + Alanine Another example is the conversion of aspartate to glutamate via the enzyme aspartate transaminase. ... In the case of dicarboxylic aminoaciduria, where glutamate and aspartate transport are impaired, the alanine, aspartate and ...
*  Elbasvir/grazoprevir
The most important risks are Alanine transaminase elevation, hyperbilirubinemia, drug resistance development and drug ...
*  Phenelzine
... of which are alanine transaminase (ALA-T), and γ-Aminobutyric acid transaminase (GABA-T), the latter of which is not caused by ... "Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain". Cellular and ... Transaminases such as GABA-transaminase have been shown to be dependent upon vitamin B6 and may be involved in a potentially ... phenelzine causes an increase in the alanine and GABA levels in the brain and body. GABA is the major inhibitory ...
*  Ruxolitinib
Laboratory abnormalities have included alanine transaminase (ALT) abnormalities, aspartate transaminase (AST) abnormalities, ...
*  Entecavir
Laboratory tests may show an increase in alanine transaminase (ALT), hematuria, glycosuria, and an increase in lipase. Periodic ...
*  Wilson's disease
Most have slightly abnormal liver function tests such as a raised aspartate transaminase, alanine transaminase and bilirubin ...
*  AST/ALT ratio
Aspartate transaminase Alanine transaminase Liver function tests Elevated transaminases Nyblom H, Berggren U, Balldin J, Olsson ... The AST/ALT ratio is the ratio between the concentrations of the enzymes aspartate transaminase (AST) and alanine transaminase ... De Ritis F, Coltorti M, Giusti G (July 2006). "An enzymic test for the diagnosis of viral hepatitis: the transaminase serum ...
*  Tocilizumab
The enzyme alanine transaminase was also elevated in at least 5% of patients, but in most cases without symptoms. Elevated ...
*  TBC1D10A
... alanine transaminase and alkaline phosphatase levels. GRCh38: Ensembl release 89: ENSG00000099992 - Ensembl, May 2017 GRCm38: ...
*  Pirfenidone
... can increase hepatic enzyme levels, especially those of aspartate transaminase (AST), alanine transaminase (ALT) ...
*  Alpha-Ketoglutaric acid
The alanine transaminase (ALT) enzyme converts α-Ketoglutarate and L-alanine to L-glutamate and pyruvate, respectively, as a ...
*  Thioacetamide
... which include elevation in the levels of serum alanine transaminase, aspartate transaminase and aspartic acid. Schwarz, G. ( ...
*  Asparagine-oxo-acid transaminase
This enzyme participates in alanine and aspartate metabolism and tetracycline biosynthesis. It employs one cofactor, pyridoxal ... In enzymology, an asparagine-oxo-acid transaminase (EC 2.6.1.14) is an enzyme that catalyzes the chemical reaction L-asparagine ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ...
*  Transaminase
... and alanine transaminase (ALT), also called alanine aminotransferase (ALAT) or serum glutamate-pyruvate transaminase (SGPT). ... Two important transaminase enzymes are aspartate transaminase (AST), also known as serum glutamic oxaloacetic transaminase ( ... This alanine cycle is analogous to the Cori cycle, which allows anaerobic metabolism by muscles. The transaminase enzymes are ... Valproic acid - a GABA transaminase inhibitor KARMEN, A; WROBLEWSKI, F; LADUE, JS (January 1955). "Transaminase activity in ...