... has been shown to enhance glomerular filtration rate (GFR) and to exert nephroprotective effects. Agmatine has been ... It is also found that many fermented foods contain agmatine. Agmatine is present in small amounts in plant-, animal-, and fish- ... In 1994, endogenous agmatine synthesis in mammals was discovered. Agmatine biosynthesis by arginine decarboxylation is well- ... A number of potential medical uses for agmatine have been suggested. Agmatine produces mild reductions in heart rate and blood ...

In enzymology, an agmatine deiminase (EC 3.5.3.12) is an enzyme that catalyzes the chemical reaction agmatine + H2O ⇌ {\ ... The systematic name of this enzyme class is agmatine iminohydrolase. This enzyme is also called agmatine amidinohydrolase. This ... Smith TA (1969). "Agmatine iminohydrolase in maize". Phytochemistry. 8 (11): 2111-2117. doi:10.1016/S0031-9422(00)88168-6. ... displaystyle \rightleftharpoons } N-carbamoylputrescine + NH3 Thus, the two substrates of this enzyme are agmatine and H2O, ...

In enzymology, an agmatine kinase (EC 2.7.3.10) is an enzyme that catalyzes the chemical reaction ATP + agmatine ⇌ {\ ... The systematic name of this enzyme class is ATP:agmatine N4-phosphotransferase. Other names in common use include phosphagen ... displaystyle \rightleftharpoons } ADP + N4-phosphoagmatine Thus, the two substrates of this enzyme are ATP and agmatine, ... phosphokinase, and ATP:agmatine 4-N-phosphotransferase. Piccinni E, Coppellotti O (1979). "Phosphagens in protozoa. II. ...

Other names in common use include p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase, agmatine coumaroyltransferase, and 4- ... In enzymology, an agmatine N4-coumaroyltransferase (EC 2.3.1.64) is an enzyme that catalyzes the chemical reaction 4-coumaroyl- ... The systematic name of this enzyme class is 4-coumaroyl-CoA:agmatine N4-coumaroyltransferase. ... the two substrates of this enzyme are 4-coumaroyl-CoA and agmatine, whereas its two products are CoA and N-(4-guanidinobutyl)-4 ...

Agmatine (putative endogenous ligand at I1; also interacts with NMDA, nicotinic, and α2 adrenoceptors) Apraclonidine (α2 ...

The systematic name of this enzyme class is agmatine amidinohydrolase. Other names in common use include agmatine ureohydrolase ... "Entrez Gene: AGMAT agmatine ureohydrolase (agmatinase)". Morris SM (2004). "Vertebrate agmatinases: what role do they play in ... In enzymology, an agmatinase (EC 3.5.3.11) is an enzyme that catalyzes the chemical reaction agmatine + H2O ⇌ {\displaystyle \ ... Vicente C, Legaz ME (1982). "Preparation and properties of agmatine amidinohydrolase of Evernia prunastri". Physiol. Plant. 55 ...

Gibson DA, Harris BR, Rogers DT, Littleton JM (October 2002). "Radioligand binding studies reveal agmatine is a more selective ... Reis DJ, Regunathan S (May 2000). "Is agmatine a novel neurotransmitter in brain?". Trends in Pharmacological Sciences. 21 (5 ... glycine site antagonist Agmatine - endogenous polyamine site antagonist Argiotoxin-636 - naturally occurring dizocilpine or ...

Agmatine is transformed into N-carbamoylputrescine by agmatine imino hydroxylase (AIH). Finally, N-carbamoylputrescine is ... In one pathway, arginine is converted into agmatine. The conversion is catalyzed by the enzyme arginine decarboxylase (ADC). ... Srivenugopal KS, Adiga PR (September 1981). "Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. ...

Alterations in production of endogenous NMDA antagonists such as agmatine and kynurenic acid have been shown in schizophrenia. ... Robust negative feedback at NMDA from kynurenic acid, magnesium, zinc, and agmatine prevents runaway feedback. Misregulation of ... "Increased plasma agmatine levels in patients with schizophrenia". Journal of Psychiatric Research. 47 (8): 1054-60. doi:10.1016 ...

... is also a precursor for urea, ornithine, and agmatine; is necessary for the synthesis of creatine; and can also be ... Moreover, cluster analyses revealed that L-arginine and its main metabolites L-citrulline, L-ornithine and agmatine formed ... Assays also confirmed significantly reduced levels of γ-aminobutyric acid (GABA), but increased agmatine concentration and ... used for the synthesis of polyamines (mainly through ornithine and to a lesser degree through agmatine, citrulline, and ...

... the biosynthetic enzyme for agmatine". Biochimica et Biophysica Acta (BBA) - General Subjects. 1670 (2): 156-164. doi:10.1016/j ...

Agmatine: Blocks NMDA receptors and other cation ligand-gated channels. Can also potentiate opioid analgesia. Argiotoxin: ...

Agmatine is also often used as an alternative or supplement to arginine. Taurine is also a common ingredient in pre-workout, ... Laube G, Bernstein HG (July 2017). "Agmatine: multifunctional arginine metabolite and magic bullet in clinical neuroscience?". ...

Srivenugopal KS, Adiga PR (1981). "Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and ... Roon RJ, Barker HA (1972). "Fermentation of agmatine in Streptococcus faecalis: occurrence of putrescine transcarbamoylase". J ...

Gong S, Richard H, Foster JW (August 2003). "YjdE (AdiC) is the arginine:agmatine antiporter essential for arginine-dependent ... Iyer R, Williams C, Miller C (November 2003). "Arginine-agmatine antiporter in extreme acid resistance in Escherichia coli". ... catalyzes the conversion of L-arginine into agmatine and carbon dioxide. The process consumes a proton in the decarboxylation ...

Srivenugopal KS, Adiga PR (1981). "Enzymic conversion of agmatine to putrescine in Lathyrus sativus seedlings. Purification and ...

Both the gabD and gabT genes were shown, in various experiments, to be induced by metabolites such as agmatine and lysine that ... Chou HT, Kwon DH, Hegazy M, Lu CD (March 2008). "Transcriptome analysis of agmatine and putrescine catabolism in Pseudomonas ...

In addition, agmatine may play an important regulatory role in mammals. Formiminoglutamase catalyses the fourth step in ... Agmatinase hydrolyses agmatine to putrescine, the precursor for the biosynthesis of higher polyamines, spermidine and spermine ... and play important roles in arginine/agmatine metabolism, the urea cycle, histidine degradation, and other pathways. Arginase, ...

Goldschmidt, Millicent C.; Lockhart, Betty M. (1 August 1971). "Simplified rapid procedure for determination of agmatine and ...

Another pathway in plants starts with decarboxylation of L-arginine to produce agmatine. The imine functional group in agmatine ... then is hydrolysed by agmatine deiminase, releasing ammonia, converting the guanidine group into a urea. The resulting N- ...

... is generated in the cell by attachment of agmatine to the C2-oxo group of cytidine by TiaS. Agmatine in turn is a ... Conjugation of agmatine moiety at the C2 carbon of C34 induces a tautomeric conversion of C34 which alters its hydrogen bonding ... In step three, the primary amino group of agmatine attacks the C2 carbon of the p-C34 intermediate to release γ-Pi and form ... Agmatidine is similar to lysidine in that the C2-oxo group of cytidine is replaced by the aminoguanidine agmatine instead of by ...

Later, he discovered agmatine in herring roe and devised a method for preparing it. Another of Kossel's students was American ...

Ikeuchi Y, Kimura S, Numata T, Nakamura D, Yokogawa T, Ogata T, Wada T, Suzuki T, Suzuki T (April 2010). "Agmatine-conjugated ...

Quistad GB, Lam WW, Casida JE (1993). "Identification of bis(agmatine)oxalamide in venom from the primitive hunting spider, ...

L-ornithine is converted to L-arginine, which is then decarboxylated via PLP to form agmatine. Hydrolysis of the imine derives ...

L-Ornithine is converted to L-arginine, which is then decarboxylated via PLP to form agmatine. Hydrolysis of the imine derives ...

It catabolizes a variety of energy sources, including glycerol, lactate, malate, citrate, arginine, agmatine, and many keto ...

Gründemann D, Hahne C, Berkels R, Schömig E (2003). "Agmatine is efficiently transported by non-neuronal monoamine transporters ...

Gründemann D, Hahne C, Berkels R, Schömig E (2003). "Agmatine is efficiently transported by non-neuronal monoamine transporters ...

... is a hydroxycinnamic acid amide derivative (HCAA) as well as a dimer of coumaroyl agmatine, and is plentiful during ... The first step in the biosynthesis of hordatine A is characterized by the use of the enzyme agmatine coumaroyltransferase (ACT ... Hordatines and their hydroxycinnamoyl agmatine precursors are of interest because of their antifungal activity against plant ... which catalyzes the formation of p-coumaroylagmatine from p-coumaroyl-CoA and agmatine. The second step in the biosynthesis of ...