*  Amyloid beta
"Effects of memantine and galantamine on cognitive performance in aged rhesus macaques". Neurobiology of Aging. 34 (4): 1126-32 ... Mutations in APP associated with early-onset Alzheimer's have been noted to increase the relative production of Aβ42, and thus ... Autosomal-dominant mutations in APP cause hereditary early-onset Alzheimer's disease (a.k.a. familial AD). This form of AD ... Neurobiology of Aging. 58: 68-76. doi:10.1016/j.neurobiolaging.2017.05.019. Olsson F, Schmidt S, Althoff V, Munter LM, Jin S, ...
*  Age of onset
The age of onset is a medical term referring to the age at which an individual acquires, develops, or first experiences a ... meaning that most people develop scoliosis when they are of an age between ten and fifteen years. The age of onset of mental ... For instance, the general age of onset for the spinal disease scoliosis is "10-15 years old," ... "Adult mental health disorders and their age at onset". The British Journal of Psychiatry. 202 (s54): s5-s10. doi:10.1192/bjp.bp ...
*  Chemical biology
Cohen E, Bieschke J, Perciavalle RM, Kelly JW, Dillin A (2006). "Opposing Activities Protect Against Age-Onset Proteotoxicity ... Misfolding occurs more often in aged individuals or in cells exposed to a high degree of oxidative stress, but a fraction of ... the ability to efficiently and quickly synthesize short peptides came of age with the development of Bruce Merrifield's solid ...
*  Juvenile xanthogranuloma
In 5% to 17% of people, the disorder is present at birth, but the median age of onset is two years. JXG is a benign idiopathic ... "Old-Age-Onset Subconjunctival Juvenile Xanthogranuloma without Limbal Involvement." BMC Ophthalmology 14 (2014): 24. PMC. Web. ... JXG usually manifests with multiple lesions on the head and neck in cases with children under six months of age. The condition ... Of patients with ocular JXG, 92% are younger than the age of two. Although cutaneous JXG usually disappear spontaneously, ...
*  Juvenile idiopathic arthritis
The additional symptoms and age onset, as Behcet syndrome is rarely diagnosed before school age, can help differentiate. Lyme ... "Juvenile" in this context refers to an onset before age 16, "idiopathic" refers to a condition with no defined cause, and " ... The disease commonly occurs in children from the ages of 1 to 6, but it may develop as late as 15 years of age. It is a subset ... Children with late-onset oligoarticular JIA are at risk for sacroiliitis and spondyloarthropathy; late-onset oligoarticular JIA ...
*  Progressive retinal atrophy
The other is inherited as an autosomal recessive trait and has a middle age onset. Early onset PRA has also been reported in ... Glen of Imaal Terrier - CRD3 results in gradual blindness with onset around 4 years of age (often detectable as retinal ... One is inherited as an autosomal dominant trait and has an early age onset. ... This type of PRA has an early onset of severe vision loss. It is caused by a defect in the gene for cGMP-phosphodiesterase, ...
*  Spasmodic torticollis
... age of onset, and cause. The disorder is categorized as early onset if the patient is diagnosed before the age of 27, and late ... most patients show symptoms from ages 50-69. The average onset age of spasmodic torticollis is 41. Geyer HL; Bressman SB. (2006 ... Some feel an invisible tremor of their head for a few months at onset. Then the head may turn, pull or tilt in jerky movements ... The prevalence rate of spasmodic torticollis also increases with age, ...
*  ROHHAD
... median age 3 years); Respiratory Manifestations: Alveolar Hypoventilation (median onset age 6.2 years); Cardiorespiratory ... Rapid-onset Obesity with Hypothalamic dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD syndrome) is a very rare ... Each child has the symptoms above at different ages, yet most symptoms are eventually present. Many children are misdiagnosed ... July 2007). "Rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation presenting in ...
*  Jagdish Kashibhai Patel
Help the Aged "On-set of Blindness" (PDF). Blind People's Association. 2015. Retrieved October 10, 2015. "BPA". BPA. 2015. ... He lost his eye sight at the age of 8 and did his early schooling at the Calcutta Blind School, Behala. After securing a ... India Confederation of the Blind Award in 1987 and the International Award for Community Services Overseas of the Help the Aged ...
*  Lamin
This genetic condition is characterized by rapid onset aging. Children appear normal at birth, but as they grow and develop ... "A Comeback for the Ages: Lamin's connection with aging has reinvigorated research". Retrieved 2016-11-24. Young, Stephen G.; ... Affected individuals also develop age-related health problems such as atherosclerosis and high blood pressure. People with this ... resulting in a higher rate of cell death and therefore a higher rate of aging. Current studies are investigating the effects of ...
*  Hereditary spastic paraplegia
The age of onsets has two points of maximum at age 2 and around age 40. New findings propose that an earlier onset leads to a ... No differences in rate relating to gender were found, and average age at onset was 24 years. In the United States, Hereditary ... Hereditary spastic paraplegias can be classified based on the symptoms; mode of inheritance; the patient's age at onset; the ... In the past, HSP has been classified as early onset beginning in early childhood or later onset in adulthood. ...
*  Juvenile polyposis syndrome
Age of onset is variable. The term 'Juvenile' in the title of Juvenile polyposis syndrome refers to the histological type of ... These usually begin appearing before age 20, but the term juvenile refers to the type of polyp, not to the age of the affected ... the polyps rather than age of onset. Affected individuals may present with rectal bleeding, abdominal pain, diarrhea or anemia ...
*  Neurofibromatosis type I
Age of onset is puberty. Progressive in number and size. Not malignant. Can be treated with CO2 lasers or by removal by a ... The following is a list of conditions and complications associated with NF-1, and, where available, age range of onset and ... NF-1 is an age specific disease; most signs of NF-1 are visible after birth (during infancy), but many symptoms of NF-1 occur ... Their exact identity remains a bit of a mystery since they disappear over time (usually, by age 16), and they are not typically ...
*  Gordon Woods
Gordon's hypothesis was that excessive intracellular calcium in human cells could be an underlying factor in age-onset diseases ... to use the horse as a model to try to understand age-onset diseases in people. ... Gordon Woods died unexpectedly at the Medical Center of the Rockies in Loveland, Colorado, at the age of 57. He was survived by ...
*  Paramesonephric duct
Malfunction in the ovaries and age onset abnormalaites can also be associated with most paramesonephric ducts. Most ...
*  Muir-Torre syndrome
Age of onset of first sebaceous neoplasm: 2 = 2 points. Personal history of Lynch related cancers: No = 0 points, Yes = 1 point ... Muir noted a patient with many keratoacanthomas who went on to develop several internal malignancies at a young age. Torre ... at least 1 case of colorectal cancer younger than age 50 years, a diagnosis of familial adenomatous polyposis has been excluded ... sebaceous neoplasm warrants routine immunohistochemical screening regardless of patient's age or other clinical characteristics ...
*  Pituitary apoplexy
The average age at onset is 50; cases have reported in people between 15 and 90 years old. Men are affected more commonly than ... The most common symptom, in over 95% of cases, is a sudden-onset headache located behind the eyes or around the temples. It is ... and if surgery is undertaken within a week of the onset of symptoms. Those with relatively mild visual field loss or double ...
*  Posterior vitreous detachment
Age and refractive error play a role in determining the onset of PVD in a healthy person. PVD is rare in emmetropic people ... "Age of onset of posterior vitreous detachment". Current Opinion in Ophthalmology. 7 (3): 73-6. doi:10.1097/00055735-199606000- ... With age the vitreous humor changes, shrinking and developing pockets of liquefaction, similar to the way a gelatin dessert ... In absence of retinal tears, the usual progress is that the vitreous humor will continue to age and liquefy and floaters will ...
*  Adie syndrome
Average age of onset is 32 years. Ross' syndrome Ciliary ganglion National Institute of Neurological Disorders and Stroke. " ...
*  HLA-DR15
Masterman T, Ligers A, Olsson T, Andersson M, Olerup O, Hillert J (2000). "HLA-DR15 is associated with lower age at onset in ... DR15 is positively associated Goodpasture syndrome, early age onset multiple sclerosis, pernicious anaemia, sarcoidosis, ...
*  Primary hypertrophic osteoathropathy
The age of onset is often in puberty. Of the described cases, as high as 80% of the affected individuals was suffering from the ... After onset, the disease stabilizes after about 5-20 years. Life of PDP patients can be severely impaired. Currently, ... disease prior to the age of 18. However, Latos-Bielenska et al. stated that this percentage should be lower, because also ...
*  German Cancer Aid
The mean age of onset is 69 years. The most common cancer in women is breast cancer. Every year 59,510 women are diagnosed with ... The mean main age of onset is 64 years. 40 percent of affected women are younger than 60 years. Ranked second in women is colon ...
*  Sex differences in schizophrenia
Males tend to have a younger age of onset by about one year. Females tend to have lower verbal IQ scores at this age. Onset is ... regardless of age of onset. The first manifestations of schizophrenia may occcur at the same age in both males and females, but ... Gender differences in age at the first hospital admission are typically due to a more acute onset in females. Smoking is more ... During middle age, more women than men experience onset of schizophrenia. The reason for this phenomenon is unknown. Theories ...
*  Multiple myeloma
The average age of onset is 70 years. Older patients are often experiencing other serious diseases, which affect survival. ... People over age 65 and people with significant concurrent illness often cannot tolerate stem cell transplantation. For these ... It usually occurs around the age of 61 and is more common in men than women. Without treatment, typical survival is seven ... The preferred treatment for those under the age of 65 is high-dose chemotherapy, commonly with bortezomib based regimens, and ...
*  Epidemiology of diabetes mellitus
The average age on onset is 42.5 years. Nearly 1 million Indians die due to diabetes every year. According to the Indian Heart ... In Australia, the age-standardised prevalence of self-reported diabetes in indigenous Australians is almost four times that of ... As of 2006, about 18.3% (8.6 million) of Americans age 60 and older had diabetes, according to the ADA. Diabetes mellitus ... Accounting for the younger age structure in Aboriginal populations, the prevalence of diabetes is 2-3 times higher among First ...
*  Split hand syndrome
A slow onset and a lack of pain or sensorial symptoms are arguments against a lesion of the spinal root or plexus brachialis. ... To an extent, these features can also be seen in normal aging (although technically, the apparent muscle wasting is sarcopenia ... Voermans NC, Schelhaas HJ, Munneke M, Zwarts MJ (December 2006). "Dissociated small hand muscle atrophy in aging: the 'senile ...
*  Tumefactive multiple sclerosis
The median age of onset is 37 years. As in general MS, there are differences for gender, ethnicity and geographic location. ... While these associations have been made, it is still unclear how they result in an increased risk of MS onset. Symptoms of ... "Late-onset tumefactive multiple sclerosis". Radiat Med. 26: 549-552. doi:10.1007/s11604-008-0273-4. CS1 maint: Multiple names: ...