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*  Alpha blocker
However, the most common type of alpha blocker is usually an α1 blocker. Non-selective α-adrenergic receptor antagonists ... "Alpha-Adrenoceptor Antagonists (Alpha-Blockers)" (PDF). British Hypertension Society. "CV Pharmacology , Alpha-Adrenoceptor ... Bylund, D.B. (February 1, 1992). "Subtypes of alpha 1- and alpha 2-adrenergic receptors". The FASEB Journal. 6: 832-839. ... are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha- ...
*  Metazosin
... is an antihypertensive alpha-adrenergic antagonist. Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; Votavová, M; ... a novel alpha-adrenergic antagonist". Biopharmaceutics & drug disposition. 10 (6): 581-9. PMID 2575403. ...
*  Tiodazosin
... is an alpha-1 adrenergic antagonist. Terazosin Chiang, J; Hermodsson, G; Oie, S (1991). "The effect of alpha 1-acid ... glycoprotein on the pharmacological activity of alpha 1-adrenergic antagonists in rabbit aortic strips". The Journal of ...
*  Prazosin
A larger controlled Phase II "Clinical Trial of the Adrenergic Alpha-1 Antagonist Prazosin for Alcohol Dependence" is currently ... Day, H. E.; Campeau, S.; Watson Jr, S. J.; Akil, H. (1997). "Distribution of alpha 1a-, alpha 1b- and alpha 1d-adrenergic ... "A pilot trial of the alpha-1 adrenergic antagonist, prazosin, for alcohol dependence". Alcoholism: Clinical and Experimental ... Antagonist of alpha-1 adrenoceptors on vascular smooth muscle, thereby inhibiting the vasoconstrictor effect of circulating and ...
*  Pelvic pain
Yang G, Wei Q, Li H, Yang Y, Zhang S, Dong Q (2006). "The effect of alpha-adrenergic antagonists in chronic prostatitis/chronic ...
*  Chronic prostatitis/chronic pelvic pain syndrome
Yang G, Wei Q, Li H, Yang Y, Zhang S, Dong Q; Wei; Li; Yang; Zhang; Dong (2006). "The effect of alpha-adrenergic antagonists in ... Alpha blockers and/or antibiotics appear to be the most effective with NSAIDs such as ibuprofen providing lesser benefit. ... The effectiveness of alpha blockers (tamsulosin, alfuzosin) is questionable in men with CPPS. A 2006 meta-analysis found that ... He, L.; Wang, Y.; Long, Z.; Jiang, C. (Dec 2009). "Clinical Significance of IL-2, IL-10, and TNF-alpha in Prostatic Secretion ...
*  Olney's lesions
Conversely, coadministration of NMDA-antagonists with alpha-2 adrenergic antagonists, like yohimbine could theoretically ... Drugs that work to suppress NAN include anticholinergics, benzodiazepines, barbiturates and agonists at the alpha-2 adrenergic ... D.Wozniak - NMDA Antagonist Neurotoxicity: Mechanism and Prevention] Olney J, Labruyere J, Wang G, Wozniak D, Price M, Sesma M ... The potency of the drugs in producing these neurotoxic changes corresponded with their potency as NMDA antagonists: i.e. MK-801 ...
*  C17H19N3O
... a reversible nonselective alpha-adrenergic antagonist Piberaline, a psychoactive drug. ...
*  Bunazosin
Systemic Alpha-1 adrenergic receptor antagonists have been implicated in Intraoperative Floppy Iris Syndrome (IFIS). Bunazosin ... Bunazosin (INN) is an alpha 1 antagonist. Bunazosin was initially developed to treat benign prostatic hyperplasia (BPH). It has ...
*  Boldine
In addition, it has alpha-adrenergic antagonist activities in vascular tissue, and it has also been reported to have ...
*  Transurethral needle ablation of the prostate
... needle ablation of the prostate as an alternative to transurethral resection of the prostate when alpha-adrenergic antagonist ...
*  Alpha-1 blocker
Prazosin has been established as an effective and safe, brain active alpha-1 adrenergic receptor antagonist. It can be used ... Alpha-1 blockers (also called alpha-adrenergic blocking agents) constitute a variety of drugs that block alpha-1-adrenergic ... DrugDigest - Alpha blockers RxList.com - Tamsulosin alpha-Adrenergic Blockers at the US National Library of Medicine Medical ... Alpha-1 blockers have no effect on renin release or cardio output. Alpha-1 blocker, blocks alpha receptors and it relaxes the ...
*  Nicergoline
... is an ergot alkaloid derivative that acts as a potent and selective alpha-1A adrenergic receptor antagonist. The ... Persons suffering from acute bleeding, myocardial infarction (heart conditions), hypertension, bradycardia or using alpha or ... "Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat". ...
*  Sympatholytic
They are primarily postsynaptic adrenergic receptor antagonists (alpha and beta adrenergic receptor antagonists, or "blockers ... ICI-118,551 Highly selective β2-adrenergic receptor antagonist - No known clinical applications, but used in experiments due to ... α1 antagonist) Doxazosin (alpha blocker) Beta blockers Non-selective agents Alprenolol Bucindolol Carteolol Carvedilol (has ... preventing postsynaptic adrenergic receptor activation and downstream signaling. Another way to inhibit adrenergic receptor ...
*  Benzoctamine
One study showed that benzoctamine, a serotonin and alpha-adrenergic antagonist, does not reduce blood pressure through a ... A possible treatment for hypertension is blocking peripheral vascular seretonergic neurons or alpha-adrenergic neurons on ... "Evidence that blood pressure reduction by serotonin antagonists is related to alpha receptor blockade in spontaneously ... Other animal studies also point to the drug as a possible mechanism by which to reduce blood pressure through the adrenergic ...
*  Rauwolscine
... a specific antagonist radioligand for brain alpha 2-adrenergic receptors". European Journal of Pharmacology. 76 (4): 461-4. doi ... Rauwolscine acts predominantly as a α2-adrenergic receptor antagonist. It has also been shown to function as a 5-HT1A receptor ... Wainscott DB, Sasso DA, Kursar JD, Baez M, Lucaites VL, Nelson DL (January 1998). "[3H]Rauwolscine: an antagonist radioligand ... Perry BD, U'Prichard DC (December 1981). "[3H]rauwolscine (alpha-yohimbine): ...
*  Azinphos-methyl
... a cholinergic and alpha-1 adrenergic antagonist, to achieve a shorter recovery time. Treatment with a combination of different ... Competitive antagonists of AChE can be used for pre-treatment. They can reduce mortality, which is caused by exposure to AzM. ... These two treatments are also used together, some patients are namely treated with atropine (a competitive antagonist of AChE) ...
*  Methylergometrine
... is a partial agonist/antagonist on serotonergic, dopaminergic and alpha-adrenergic receptors. Its specific ... dopaminergic and adrenergic receptors". In Vladimír Křen,Ladislav Cvak. Ergot: the genus Claviceps. CRC Press. pp. 411-440. ...
*  Naftopidil
... is a drug used in benign prostatic hypertrophy which acts as a selective α1-adrenergic receptor antagonist or alpha blocker. ...
*  Fenmetozole
"Effect of methoxy substitution on the adrenergic activity of three structurally related alpha 2-adrenoreceptor antagonists". ... It acts as an α2-adrenergic receptor antagonist similarly to other imidazoles like idazoxan. It was never marketed. ... Fenmetozole (DH-524) is a drug which was patented as an antidepressant, but was later studied as an antagonist of the effects ...
*  Abanoquil
... is an α1-adrenergic receptor antagonist. Alpha blocker Tham, TC; Guy, S; Shanks, RG; Harron, DW (1992). "Dose-dependent alpha 1 ... antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man". British ...
*  L-765,314
... is a drug which acts as a potent and selective antagonist for the Alpha-1 adrenergic receptor subtype α1B. It has ... Yang XP, Chiba S (August 2002). "Effects of L-765,314, a selective and potent alpha 1B-adrenoceptor antagonist, on periarterial ... a potent and selective alpha1b adrenergic receptor antagonist ". Journal of Medicinal Chemistry. 41 (8): 1205-8. doi:10.1021/ ... alpha(1D)-, and alpha(2)-adrenoceptors". European Journal of Pharmacology. 613 (1-3): 86-92. doi:10.1016/j.ejphar.2009.04.011. ...
*  Tiamenidine
... relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists". Journal ... It acts as a centrally-acting α1 and α2 adrenergic receptor antagonist (with IC50 4.85 μM and 0.0091 μM, respectively). In ... "Electrophysiologic and Hemodynamic Effects of Chronic Oral Therapy With the Alpha 2-agonists Clonidine and Tiamenidine in ...
*  Alpha-1 adrenergic receptor
... relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and antagonists". Journal ... The alpha-1 (α1) adrenergic receptor is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G-protein. It ... Note that only active muscle α1-adrenergic receptors will be blocked. Resting muscle will not have its α1-adrenergic receptors ... Adrenergic receptor Graham, Robert (May 1, 1996). "α1-Adrenergic Receptor Subtypes Molecular Structure, Function, and Signaling ...
*  Alpha-1B adrenergic receptor
Antagonists L-765,314 Risperidone Alpha-1B adrenergic receptor has been shown to interact with AP2M1. A role in regulation of ... 1994). "Cloning, expression and characterization of human alpha adrenergic receptors alpha 1a, alpha 1b and alpha 1c". Biochem ... The alpha-1B adrenergic receptor (α1B adrenoreceptor), also known as ADRA1B, is an alpha-1 adrenergic receptor, and also ... There are 3 alpha-1 adrenergic receptor subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G- ...
*  Cannabigerol
CBG has been found to act as a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and ... "Evidence that the plant cannabinoid cannabigerol is a highly potent alpha(2)-adrenoceptor agonist and moderately potent 5HT ... It also binds to the CB2 receptor as an antagonist. CBG does not trigger THC-like activity in mice, rats, gerbils and non-human ... Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid ...
*  5-HT2A receptor
... related to ketanserin such as ritanserin are more selective 5-HT2A receptor antagonists with low affinity for alpha-adrenergic ... Other antagonists are MDL-100,907 (prototype of another new series of 5-HT2A antagonists) and cyproheptadine. Pizotifen is a ... Trazodone is a potent 5-HT2A antagonist, as well as an antagonist on other serotonin receptors. Mirtazapine is a 5-HT2A, 5-HT2C ... These cells need to express both the alpha 2-6-linked sialic acid component of the 5-HT2A receptor in order to endocytose JCV. ...