Formerly investigated by Fourneau as an α-adrenergic-blocking agent, they demonstrated that it also antagonized histamine- ... 4. Synthesis and pharmacological activity of chiral 2-alkylaminomethylbenzodioxans, competitive .alpha.-adrenergic antagonists ...

... (INN; also known as meta-octopamine, 3-octopamine, and 3,β-dihydroxyphenethylamine) is an adrenergic agent used as ... Alpha-adrenergic agonists, Cardiac stimulants, Norepinephrine-dopamine releasing agents, Neurotransmitters, Phenols, ... Macdonald F (1997). Dictionary of Pharmacological Agents. CRC Press. p. 104. ISBN 978-0-412-46630-4. Retrieved 24 April 2012. ...

It is a sympathomimetic agent with marked alpha adrenergic activity that acts on alpha-receptors in the arterioles of the ... Alpha-1 adrenergic receptor agonists, Alpha-2 adrenergic receptor agonists, Decongestants, Imidazolines, 1-Naphthyl compounds, ... Naphazoline is a mixed α1- and α2-adrenergic receptor agonist. The non-hydrochloride form of Naphazoline has the molecular ...

... experiments on isolated tissue lead these investigators to conclude that hordenine was an indirectly acting adrenergic agent ... Although hordenine is capable of reacting with nitrosating agents (e.g. nitrite ion, NO2−) to form the carcinogen N- ...

"Short-term effects of early intravenous treatment with a beta-adrenergic blocking agent or a specific bradycardiac agent in ...

... binding profile of the new antihypertensive agent nebivolol and its stereoisomers compared with various beta-adrenergic ... β2-adrenergic receptor (Ki = 0.19-0.25 nM), α1-adrenergic receptor (Ki = 3.4 nM), α2-adrenergic receptor (Ki = 2,168 nM), 5- ... The affinity (Ki) of carvedilol for the β-adrenergic receptors is 0.32 nM for the human β1-adrenergic receptor and 0.13 to 0.40 ... Carvedilol is both a non-selective β-adrenergic receptor antagonist (β1, β2) and an α-adrenergic receptor antagonist (α1). The ...

... s (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block ... By reducing α1-adrenergic activity of the blood vessels, these drugs may cause hypotension (low blood pressure) and interrupt ... Alpha-1 adrenergic receptors are present in vascular smooth muscle, the central nervous system, and other tissues. When alpha ... As of 2018, prazosin is the only alpha-1 blocker known to act as an inverse agonist at all alpha-1 adrenergic receptor subtypes ...

Stimulatory factors: Beta-adrenergic agents, cholinergic agents, gastrin-releasing peptide (GRP) Inhibitory factor: ...

Alpha-2 adrenergic receptor agonists, Antihypertensive agents, Chloroarenes, Chloropyrimidines, Imidazolines, Phenol ethers, ... March 2003). "Metabolism and disposition of the antihypertensive agent moxonidine in humans". Drug Metabolism and Disposition. ... Fairbanks CA, Wilcox GL (July 1999). "Moxonidine, a selective alpha2-adrenergic and imidazoline receptor agonist, produces ... "Growth hormone secretion in response to the new centrally acting antihypertensive agent moxonidine in normal human subjects: ...

... adrenergic agents such as alpha-1 blockers and beta-blockers and alpha-2 agonists, antiplatelet agents (aspirin and clopidogrel ...

Several studies have shown that bronchodilation with β-adrenergic agents such as salbutamol may improve symptoms briefly but do ... Epinephrine is an α and β adrenergic agonist that has been used to treat other upper respiratory tract illnesses, such as croup ... This is most commonly caused by respiratory syncytial virus (RSV, also known as human pneumovirus). Other agents that cause ...

"1-Subst-phenyl-2-amino-ethanols useful as beta adrenergic agents peripheral vasodilators and hypotensive agents" Staff (5 ...

Adrenergic release inhibitors, Antihypertensive agents, Guanidines, Tetrahydroisoquinolines, All stub articles, ...

... neurotransmitter agents MeSH D27.505.519.625.050 - adrenergic agents MeSH D27.505.519.625.050.100 - adrenergic agonists MeSH ... neurotransmitter agents MeSH D27.505.696.577.050 - adrenergic agents MeSH D27.505.696.577.050.100 - adrenergic agonists MeSH ... antiviral agents MeSH D27.505.954.122.388.077 - anti-retroviral agents MeSH D27.505.954.122.388.077.088 - anti-hiv agents MeSH ... tocolytic agents MeSH D27.505.954.016 - anti-allergic agents MeSH D27.505.954.122 - anti-infective agents MeSH D27.505.954.122. ...

A norepinephrine releasing agent (NRA), also known as an adrenergic releasing agent, is a catecholaminergic type of drug that ... Monoamine releasing agent Serotonin releasing agent Dopamine releasing agent Keith Parker; Laurence Brunton; Goodman, Louis ... Another class of drugs that stimulates adrenergic activity is the adrenergic receptor agonist class. NRAs are used for a ... ISBN 978-0-7817-6879-5.[permanent dead link] Media related to Norepinephrine releasing agents at Wikimedia Commons (All ...

Adrenergic release inhibitors, Antiarrhythmic agents, Bromoarenes, Potassium channel blockers, Quaternary ammonium compounds). ... Bretylium (also bretylium tosylate) is an antiarrhythmic agent. It blocks the release of noradrenaline from nerve terminals. In ...

Alpha-2 adrenergic receptor agonists, Antihypertensive agents, Chloroarenes, Imidazolines, Phenol ethers). ... It is an α2A adrenergic receptor agonist. It was approved for use by the Food and Drug Administration in the United States in ... Lofexidine is an agonist at the α-2A, 2B, and 2C adrenergic receptor subtypes, with the highest activity at the alpha-2A ... Lofexidine is structurally analogous to clonidine, another α2 adrenergic receptor agonist used for treatment of opioid ...

Adrenergic release inhibitors, Antihypertensive agents, Chloroarenes, Guanidines, Phenol ethers, All stub articles, ... It is known to bind to non-adrenergic sites in pig kidney membranes. When β-(2,6-dichlorophenoxy)ethyl bromide (1) is reacted ... guanoxan and idazoxan bind with high affinity to non-adrenergic sites in pig kidney membranes". European Journal of ...

Method requires a specialized exercise protocol and proprietary electrodes and washout of beta-adrenergic blocking agents to ...

Beta1-adrenergic agonists, Inotropic agents, Wikipedia medicine articles ready to translate, Eli Lilly and Company brands). ... The drug is also commonly used in the hospital setting as a pharmacologic stress testing agent to identify coronary artery ... Dobutamine is a direct-acting agent whose primary activity results from stimulation of the β1-adrenoceptors of the heart, ... Dobutamine is predominantly a β1-adrenergic agonist, with weak β2 activity, and α1 selective activity, although it is used ...

Alpha-2 adrenergic receptor agonists, Antihypertensive agents, Chloroarenes, Imidazolines, All stub articles, Antihypertensive ... a new antihypertensive agent. III. Action on the secretions of the digestive tract and on the central nervous system, acute ... a new antihypertensive agent. I. Action on blood pressure and heart rate". Arzneimittel-Forschung. 25 (10): 1557-61. PMID ... a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis". ...

Alpha-1 adrenergic receptor agonists, Alpha-2 adrenergic receptor agonists, Antihypertensive agents, Chloroarenes, Imidazolines ... It is a centrally-acting α2 adrenergic receptor agonist (IC50 = 9.1 nM). It also acts as an α1-adrenergic receptor agonist to a ... "Quantitative relationships between alpha-adrenergic activity and binding affinity of alpha-adrenoceptor agonists and ...

... a new β-adrenergic blocking agent]. Folia Pharmacologica Japonica (English abstract) (in Japanese). 75 (7): 707-720. doi: ... Takahashi H, Yoshida T, Nishimura M, Nakanishi T, Kondo M, Yoshimura M (September 1992). "Beta-3 adrenergic agonist, BRL-26830A ... "β-adrenergic blocking, antiarrhythmic compound S-596". It is used in the treatment of high blood pressure and essential tremor ... "Arotinolol is a weak partial agonist on beta 3-adrenergic receptors in brown adipocytes". Canadian Journal of Physiology and ...

Beta1-adrenergic agonists, Beta2-adrenergic agonists, Catecholamines, Inotropic agents, TAAR1 agonists, Phenylethanolamines, ... Isoprenaline is a β1 and β2 adrenoreceptor agonist and has almost no activity on alpha adrenergic receptors at low levels. ... October 2011). "Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists". ...

Alpha-2 adrenergic receptor agonists, Antihypertensive agents, Attention deficit hyperactivity disorder management, ... Guanfacine is a highly selective agonist of the α2A adrenergic receptor, with low affinity for other receptors. However it may ... Uhlén S, Porter AC, Neubig RR (December 1994). "The novel alpha-2 adrenergic radioligand [3H]-MK912 is alpha-2C selective among ... Arnsten AF (October 2010). "The use of α-2A adrenergic agonists for the treatment of attention-deficit/hyperactivity disorder ...

... serotonergic agents such as mCPP and LY-293,284, adrenergic agents such as yohimbine, psychoactive agents such as THC and LSD ... A number of agents are used to provoke anxiety (anxiogens) or panic (panicogens) in experimental models. Some of the most ... This effect is in contrast to anxiolytic agents, which inhibits anxiety. Together these categories of psychoactive compounds ...

It is not an α-adrenergic agonist, does not cause vasoconstriction, and is not a pressor agent. As of 2004 there was some ... Use in sepsis has been explored in clinical trials, but use of an inotropic agent like dobutamine or dopexamine did not reduce ... Dopexamine is used in hospitals as an inotropic agent to reduce exacerbations of heart failure and to treat heart failure ... Oba Y, Lone NA (October 2014). "Mortality benefit of vasopressor and inotropic agents in septic shock: a Bayesian network meta- ...

Direct acting sympathomimetic amines, such as phenylephrine, stimulate alpha adrenergic receptors, while mixed-acting agents, ... Lacroix, Jean-Silvain (1989). "Adrenergic and non-adrenergic mechanisms in sympathetic vascular control of nasal mucosa". Acta ... A study has shown that the anti-infective agent benzalkonium chloride, which is frequently added to topical nasal sprays as a ... Adams, H. Richard (2013). "Adrenergic Agonists and Antagonists". In Riviere, Jim E.; Papich, Mark G. (eds.). Veterinary ...

... are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). Historically, alpha- ... Beta blocker Adrenergic antagonist Katzung, Bertram (1987). Basic and Clinical Pharmacology. Appleton & Lange. ISBN ... Non-selective α-adrenergic receptor antagonists include: Phenoxybenzamine Phentolamine Tolazoline Trazodone Selective α1- ... Bylund, D.B. (February 1, 1992). "Subtypes of alpha 1- and alpha 2-adrenergic receptors". The FASEB Journal. 6 (3): 832-839. ...

The minimum requirement for adrenergic agents is a primary or secondary amine separated from a substituted benzene ring by one ... By comparison, labetalol is a weaker β-adrenergic receptor blocker than propranolol, and has a weaker affinity for α-adrenergic ... vasoconstriction after blocking β-adrenergic receptors or tachycardia after blocking α-adrenergic receptors. Because the reflex ... The third, the (S,R)-isomer, is a powerful α1-adrenergic receptor blocker. The fourth isomer, the (R,R)-isomer which is also ...