... is a murine tumor cell line used for biomedical research as a model systems for adrenal cortex studies. ...
She studied tumors in the adrenal cortex, diseases that cause demyelination and the processes which result in the formation of ...
In the endocrine system, Manipura is said to be associated with the pancreas and the outer adrenal glands (the adrenal cortex ... pancreas-kidney and Adrenal function. Weak Agni (fire) in the coeliac plexus leads to incompletely digested food, thoughts and ...
... originating from the adrenal cortex in women. Approximately 10 to 15 mg of DHEA-S is secreted by the adrenal cortex per day in ... Whereas DHEA is derived mostly from the adrenal cortex but is also secreted to a lesser extent by the gonads (10%), DHEA-S is ... DHEA and DHEA-S are produced in the zona reticularis of the adrenal cortex under the control of adrenocorticotropic hormone ( ... is an endogenous androstane steroid that is produced by the adrenal cortex. It is the 3β-sulfate ester and a metabolite of ...
Rapoport R, Sklan D, Hanukoglu I (March 1995). "Electron leakage from the adrenal cortex mitochondrial P450scc and P450c11 ... is a steroid hydroxylase found in the zona glomerulosa and zona fasciculata of the adrenal cortex. Named officially the ... "Mechanism of corticotropin and cAMP induction of mitochondrial cytochrome P450 system enzymes in adrenal cortex cells" (PDF). J ... though the levels produced by the adrenal are low due to the limited availability of adrenal derived T Stárka L, Dušková M, ...
"Ultrastructural evidence for a paracrine regulation of the rat adrenal cortex mediated by the local release of catecholamines ... The adrenal medulla produces adrenomedullary hormones in chromaffin cells, cells which are very similar in structure to post- ... Gasman S, Chasserot-Golaz S, Bader MF, Vitale N (October 2003). "Regulation of exocytosis in adrenal chromaffin cells: focus on ... Adrenomedullary hormones are catecholamines secreted from the adrenal medulla by chromaffin cells, neurosecretory cells ...
... suppresses corticosteroid synthesis in the adrenal cortex by reversibly inhibiting 11β-hydroxylase, an enzyme ... including corticosteroids in the adrenal gland. As the only adrenal steroidogenesis inhibitor available for intravenous or ... September 2005). "Adrenal insufficiency in meningococcal sepsis: bioavailable cortisol levels and impact of interleukin-6 ... Wagner RL, White PF, Kan PB, Rosenthal MH, Feldman D (May 1984). "Inhibition of adrenal steroidogenesis by the anesthetic ...
Protein kinase A has been implicated in a number of diseases, including cardiovascular disease, tumors of the adrenal cortex, ... Mutations in the PRKACA gene that promote abnormal enzyme activity have been linked to disease of the adrenal gland. Several ... adrenal carcinomas and lymphomas. There is recent and growing interest in fibrolamellar hepatocellular carcinoma. The molecular ...
This did not occur with the adrenal cortex nor with any other tissue. Vulpian even came to the insight that the substance ... This was first shown by Blaschko and Arnold Welch (1908-2003) in Oxford and by Hillarp and his group in Lund for the adrenal ... A new chapter was opened when Max Lewandowsky in 1899 in Berlin observed that adrenal extracts acted on the smooth muscle of ... The experiment has been called "the first indirect demonstration of the role of the adrenal medulla as an endocrine organ and ...
Haymaker that Cushing's disease is caused by hyper function of the adrenal cortex. Anderson also worked with Joseph Abraham ...
If functional, adrenocortical adenomas can affect the normal activities of the adrenal cortex. Located within the adrenal ... Hypercortisolism Hyperaldosteronism Hyperandrogenism Adrenal gland Adrenal paraganglioma Adrenal Pheochromocytoma Adrenal ... The adrenal cortex is considered a dynamic organ in which senescent cells are replaced by newly differentiated cells. This ... In humans, the adrenal cortex comprises three concentric zones including the zona glomerulosa, zona fasciculata, and zona ...
ACTH in turn binds to G protein-coupled receptors in the adrenal cortex, especially in the zona fasciculata of the adrenal ... studies show that neglected children have poor cerebral hemisphere integration and underdevelopment of the orbitofrontal cortex ...
Expression in the Adrenal Cortex: Precedent for non-Immunological Roles in Normal and Neoplastic Human Tissues". Endocrine ... studies conducted in GRID2-knockout mice suggest that GRID2 may be present in lymphocytes as well as in the adrenal cortex, ... Berenova M, Mandakova P, Sima P, Slipka J, Vozeh F, Kocova J, Cervinkova M, Sykora J (2002). "Morphology of Adrenal Gland and ...
... and adrenal cortex. Hormonal therapy may also be used in the treatment of paraneoplastic syndromes or to ameliorate certain ... Aminoglutethimide inhibits both aromatase and other enzymes critical for steroid hormone synthesis in the adrenal glands. It ... but other tissues continue to produce estrogen through the action of the enzyme aromatase on androgens produced by the adrenal ... suppression of adrenal androgen production and plasma estrone sulfate formation). Fluoxymesterone, an anabolic steroid ( ...
... of the cells of the adrenal cortex. The US EPA has classified dicofol as a Group C, possible human carcinogen. There is limited ...
The white matter of the brain, the Leydig cells of the testes and the adrenal cortex are the most severely affected systems. ... The most severely affected tissues are the myelin in the central nervous system, the adrenal cortex, and the Leydig cells in ... Hormone replacement is standard for ALD patients demonstrating adrenal insufficiency. Adrenal insufficiency does not resolve ... Onset of adrenal insufficiency is often the first symptom, appearing as early as two years of age. ALD is caused by mutations ...
It was first isolated in 1936 from the adrenal cortex by Tadeus Reichstein at the Pharmaceutical Institute in the University of ... Hormones of the suprarenal cortex, Sex hormones, Steroid hormones, Triketones). ...
Angiotensin II exerts system wide effects, triggering aldosterone release from the adrenal cortex, direct vasoconstriction, and ...
Omura T, Sanders E, Estabrook RW, Cooper DY, Rosenthal O (1966). "Isolation from adrenal cortex of a nonheme iron protein and a ...
... expression in the adrenal cortex: precedent for non-immunological roles in normal and neoplastic human tissues". Endocrine ... B-lymphocytes and aldosterone-producing cells of the human adrenal cortex. Purkinje cells show two distinct forms of ... Purkinje cells migrate toward the outer surface of the cerebellar cortex and form the Purkinje cell layer. Purkinje cells are ... 432-4. ISBN 978-0-87893-697-7. Tyrrell, T; Willshaw, D (1992-05-29). "Cerebellar cortex: its simulation and the relevance of ...
December 1993). "Effect of the serotonin-4 receptor agonist zacopride on aldosterone secretion from the human adrenal cortex: ... It is thought to do this by stimulating the 5-HT4 receptors on the adrenal glands. Zacopride also stimulated aldosterone ... secretion when applied to human adrenal glands in vitro. No significant changes were observed in renin, ACTH, or cortisol ...
Much of the function of this gene is not yet known, but it is expressed mostly in the brain and adrenal cortex. TBC1D30, also ... The protein is mostly found to be expressed in tissues of the brain and adrenal glands. There is a microRNA binding site within ...
... expression in the adrenal cortex: precedent for non-immunological roles in normal and neoplastic human tissues". Endocrine ... the VPREB3 protein is also present in Purkinje cells of the cerebellum and in the zona glomerulosa of the adrenal. GRCh38: ...
... is embedded in the smooth endoplasmic reticulum of the cells of the adrenal cortex. It catalyzes hydroxylation of 17α- ... December 2007). "Testicular adrenal rest tumors and Leydig and Sertoli cell function in boys with classical congenital adrenal ... Inborn errors of steroid metabolism Congenital adrenal hyperplasia Adrenal insufficiency Disorders of sexual development ... 2000). Glucocorticoid Therapy and Adrenal Suppression. MDText.com. PMID 25905379. Rabhan NB (December 1968). "Pituitary-adrenal ...
... which causes the adrenal cortex to release corticosteroids. This chain reaction occurs when faced with a threatening situation ... This increase in adrenal output raises the physical strength and endurance levels of the person and sharpens their senses, ... Studies have suggested that glucose, together with epinephrine from the adrenal medulla have an effect on memory. Although high ... Gold, Paul E. (2014). "Regulation of memory - from the adrenal medulla to liver to astrocytes to neurons". Brain Research ...
... on Nucleic Acids and Subcellular Elements of the Adrenal Cortex. The Journal of Biophysical and Biochemical Cytology, 2(2), 115 ...
... hormone that regulates the secretion of mainly glucocorticoids from the cells of the zona fasciculata of the adrenal cortex. ... Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. A study ... essential for normal steroidogenesis and the maintenance of normal adrenal weight, and β-lipotropin are the major end-products ...
The fenestrated capillaries of the pituitary, adrenal cortex and pancreatic isle have also been known to regress as an effect ...
Sympathetic stimulation triggers the release of norepinephrine from the cardiac nerves and also stimulates the adrenal cortex ...
The adrenal cortex is made of three zones: zona glomerulosa, zona fasciculata and zona reticularis. The main zone that ... Both proteins are also found in the undifferentiated region of the adrenal gland, where there is a small population of adrenal ... in the adrenal gland leading to stimulation of glucocorticoid synthesis. Human MRAP is found mainly in the adrenal gland and ... MRAP mutations were found to disable the movement of MC2 to the cell surface of adrenal gland cells; this would make MC2 ...