"Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred ... Adoptive cell transfer (ACT) is the transfer of cells into a patient. The cells may have originated from the patient or from ... Adoptive Transfer at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Adoptive Immunotherapy at the U.S. ... The adoptive transfer of tumor-specific effector T cells knocked out or knocked down for CISH resulted in a significant ...
May 1995). "Prolonged disease-free period in patients with advanced epithelial ovarian cancer after adoptive transfer of tumor- ... July 2003). "Tumor-localization by adoptively transferred, interleukin-2-activated NK cells leads to destruction of well- ... Recently an article has been published in which it has been described that the in vitro expansion of NK cells is decreased in ... Adoptive Immuno cell therapy of cancer was first introduced by Steven Rosenberg and his colleagues of National Institute of ...
Activated and stimulated T cells can be studied in this biomimetic contex and used for adoptive transfer as an immunotherapy. ... These T cells can be then re-infused or adoptively transferred into the patient for effective cancer therapy. This technology ... For instance, it has been observed that in vitro CD4+ T cell activation by MHC-containing liposomes results in T cell ...
Adoptive cell transfer in vitro cultivates autologous, extracted T cells for later transfusion. Alternatively, Genetically ... October 2005). "Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor- ... Clinical responses to adoptive transfer of T cells were observed in patients with metastatic melanoma resistant to multiple ... Rosenberg SA, Restifo NP, Yang JC, Morgan RA, Dudley ME (April 2008). "Adoptive cell transfer: a clinical path to effective ...