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*  Rectal administration
... uses the rectum as a route of administration for medication and other fluids, which are absorbed by the ... Finally, rectal administration can allow patients to remain in the home setting when the oral route is compromised. Unlike ... The rectal route of administration is useful for patients with any digestive tract motility problem, such as dysphagia, ileus, ... Rectal administration of medication may be performed with any of the following: A suppository, a drug delivery system inserted ...
*  End-of-life care
"Biopharmaceutics of rectal administration of drugs in man. Absorption rate and bioavailability of phenobarbital and its sodium ... is a specialized catheter designed to provide comfortable and discreet administration of ongoing medications via the rectal ... "Rectal drug administration: clinical pharmacokinetic considerations". Clin Pharmacokinetics. 7 (4): 285-311. doi:10.2165/ ... The catheter was developed to make rectal access more practical and provide a way to deliver and retain liquid formulations in ...
*  Enteral administration
... and rectal. Parenteral administration is via a peripheral or central vein. In pharmacology, the route of drug administration is ... Rectal administration usually involves rectal suppositories.) The mechanism for drug absorption from the intestine is for most ... In general medicine, enteral administration (Greek enteros, "intestine") is food or drug administration via the human ... Enteral administration may be divided into three different categories, depending on the entrance point into the GI tract: oral ...
*  Vinylbital
"Pharmacokinetics and relative bioavailability of vinylbital in man after oral and rectal administration". Arzneimittel- ...
*  Nicomorphine
Pharmacokinetics via the rectal route differ, and change metabolism. Eight minutes after administration, morphine appeared ... Koopman-Kimenai PM, Vree TB, Booij LH, Dirksen R (Dec 2, 1994). "Rectal administration of nicomorphine in patients improves ... "Pharmacokinetics of nicomorphine and its metabolites in man after epidural administration. (Dutch)". Pharmaceutish Weekblad. ...
*  Enema
Improper administration of an enema can cause electrolyte imbalance (with repeated enemas) or ruptures to the bowel or rectal ... An enema might be used to clean the colon of feces first to help increase the rate of absorption in rectal administration of ... Enemas have also been used for ritual rectal drug administration such as balché, alcohol, tobacco, peyote, and other ... 201 de Boer AG, Moolenaar F, de Leede LG, Breimer DD (1982). "Rectal drug administration: clinical pharmacokinetic ...
*  Oxycodone
The bioavailability of oral administration of oxycodone averages 60-87%, with rectal administration yielding the same results; ... Therapeutic Goods Administration (June 2008). Standard for the uniform scheduling of drugs and poisons no. 23 (PDF). Canberra: ... Drug Enforcerment Administration. Retrieved 23 November 2015. "DEA Diversion Control CSA". US Dept of Justice - DEA. Retrieved ... In the United Kingdom, it is available in 10 mg/mL and 50 mg/mL formulation for intramuscular or intravenous administration. ...
*  Artesunate
... rectal administration may be given as pre-referral treatment as long as parenteral administration is initiated after transfer ... oral or rectal administration". Malaria Journal. 10: 263. doi:10.1186/1475-2875-10-263. ISSN 1475-2875. PMC 3180444 . PMID ... artesunate may be given as a single intramuscular injection or by rectal route (children < 6 years) prior to transferring care ...
*  Project 523
... oral or rectal administration". Malaria Journal. 10 (1): 263. doi:10.1186/1475-2875-10-263. PMC 3180444 . PMID 21914160. Phu, ... It is exceptionally chemically stable, and hence, is the only drug among artemisins produced as oral tablets, rectal capsule ... The drug was approved by the US Food and Drug Administration in 2009. Pharmacy and Pharmacology/Pharmacognosy and Medical Herbs ...
*  Lorazepam
Due to its poor lipid solubility, lorazepam is absorbed relatively slowly by mouth and is unsuitable for rectal administration ... There is no evidence of accumulation of lorazepam on administration up to six months. On regular administration, diazepam will ... On regular administration, maximum serum levels are attained after three days. Longer-term use, up to six months, does not ... Pregnancy and breast feeding - Lorazepam belongs to the Food and Drug Administration (FDA) pregnancy category D, which means it ...
*  Diazepam
The bioavailability after oral administration is 100%, and 90% after rectal administration. The half-life of diazepam in ... Dhillon, S; Oxley, J; Richens, A (1 March 1982). "Bioavailability of diazepam after intravenous, oral and rectal administration ... The onset of action is one to five minutes for IV administration and 15-30 minutes for IM administration. The duration of ... after rectal administration, peak plasma levels occur after 10 to 45 minutes. Diazepam is highly protein-bound, with 96 to 99% ...
*  Ergotamine
Ibraheem JJ, Paalzow L, Tfelt-Hansen P. Low bioavailability of ergotamine tartrate after oral and rectal administration in ... "Pharmacokinetics of ergotamine in healthy volunteers following oral and rectal dosing". Eur J Clin Pharmacol. 30 (3): 331-4. ...
*  Promethazine
"Pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories and oral syrup to healthy subjects ... approved by the US Food and Drug Administration (FDA), are deemed insufficient by state courts. On September 9, 2009, the FDA ... "Wyeth could have unilaterally added a stronger warning about IV-push administration" without acting in opposition to federal ... required a boxed warning be put on promethazine for injection, stating the contraindication for subcutaneous administration. ...
*  2C-C
... or rectal administration bypasses first pass metabolism, requiring about half the dose normally used orally; the effects occur ... "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Retrieved 1 October 2015. http ... As of July 9, 2012, in the United States 2C-C is a Schedule I substance under the Food and Drug Administration Safety and ... "S. 3187: Food and Drug Administration Safety and Innovation Act, Subtitle D-Synthetic Drugs". FDA
*  Route of administration
A suppository is a solid dosage form that fits for rectal administration. In hospice care, a specialized rectal catheter, ... Enteral/enteric administration usually includes oral (through the mouth) and rectal (into the rectum) administration, in the ... "Biophamacutics of rectal administration of drugs in man IX. Comparative biopharmaceutics of diazepam after single rectal, oral ... The rectal route is an effective route of administration for many medications, especially those used at the end of life. The ...
*  Phenibut
Recreational users usually take the drug orally; there are a few case reports of rectal administration and one report of ... Phenibut is available as a medication in the form of 250 mg tablets for oral administration and as a solution at a ... Administration, Australian Government Department of Health. Therapeutic Goods (31 October 2017). "3.3 Phenibut". Therapeutic ... In animals, the absolute bioavailability of phenibut was 64% after oral and intravenous administration, it appeared to undergo ...
*  Papaverine
The hydrochloride salt is available for intramuscular, intravenous, rectal and oral administration. The teprosylate is ...
*  ENPP7
Rectal administration of recombinant ENPP7 has been shown to improve ulcerative colitis in an animal study, and patients with ... Sphingomyelin can also increase the levels of ENPP7 after a long term of administration. Besides, ursodeoxycholic acid and ...
*  Removal of cannabis from Schedule I of the Controlled Substances Act
... and even rectal administration, in addition to vaporizers, which release cannabis' active ingredients into the air without ... Department of Health and Human Services Drug Enforcement Administration Food and Drug Administration Advocacy groups: Drug ... The Nixon administration took no action to implement the recommendation, however. Jon Gettman, former director of the National ... The Food and Drug Administration elaborates on this, arguing that the widespread use of cannabis, and the existence of some ...
*  Macy catheter
The rectal route of administration is highly effective as the rectal mucosa is highly vascularized tissue that allows for rapid ... The rectal route of administration is highly effective as the rectal mucosa is highly vascularized tissue that allows for rapid ... "Biophamacutics of rectal administration of drugs in man IX. Comparative biopharmaceutics of diazepam after single rectal, oral ... "Biophamacutics of rectal administration of drugs in man IX. Comparative biopharmaceutics of diazepam after single rectal, oral ...
*  Progesterone (medication)
Progesterone for vaginal administration is available in the form of a gel or insert (suppository). With vaginal and rectal ... Routes of administration that progesterone has been used by include oral, intranasal, transdermal/topical, vaginal, rectal, ... Plasma levels of progesterone are similar after vaginal and rectal administration in spite of the different routes of ... administration, and rectal administration is an alternative to vaginal progesterone in conditions of vaginal infection, ...
*  Oxymorphone
Pain relief after injection begins after about 5-10 minutes and 15-30 minutes after rectal administration, and lasts about 3-4 ... U.S. Food and Drug Administration. June 8, 2017. Retrieved October 26, 2017. Today, the U.S. Food and Drug Administration ...
*  Thebacon
The drug is most commonly taken orally as an elixir, tablet, or capsule, although rectal and subcutaneous administration has ...
*  History and culture of substituted amphetamines
Rectal administration and intravaginal administration are less-popular drug routes in the community with comparatively little ... Drug injection via intravenous administration, intramuscular administration, or subcutaneous administration carries relatively ... This method of administration is sometimes referred to as "chasing the dragon". Crystal methamphetamine and salts of ... Consequently, the administration route affects the risk for psychological dependence and addiction independently of other risk ...
*  Propiram
... has been available in oral, rectal, and injectable formulations, with bioavailability above 97% after oral ... administration. Many related compounds are known, although only propiram was ever commercialized. Propiram is currently a ...
*  Skin and skin structure infection
Superficial infections or abscesses in an anatomical site, such as the rectal area, where the risk of anaerobic or gram- ... Food and Drug Administration has changed the terminology to "acute bacterial skin and skin structure infections" (ABSSSI). The ... Food and Drug Administration. October 2013. Retrieved 2014-11-23. Xia, Fan Di; Song, Philip; Joyce, Cara; Mostaghimi, Arash ( ...