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*  Interleukin 33
... by IL-33 in vivo is believed to induce the severe pathological changes observed in mucosal organs following administration of ...
*  Cry1Ac
"Intragastric and intraperitoneal administration of Cry1Ac protoxin from Bacillus thuringiensis induces systemic and mucosal ... Cry1Ac is a mucosal adjuvant (an immune-response enhancer). It has been used in research to develop a vaccine against the ... CS1 maint: Uses authors parameter (link) Pabst R (2015). "Mucosal vaccination by the intranasal route. Nose-associated lymphoid ...
*  Gas vesicle
Potential vaccines using gas vesicle as an antigen display can be given via the mucosal route as an alternative administration ...
*  Oral candidiasis
Other physical mucosal alterations are sometimes associated with candida overgrowth, such as Fissured tongue (rarely), or ... depending on the route of administration. Topically administered corticosteroids in the mouth may take the form of mouthwashes ... Endocrine disorders, e.g., diabetes (when poorly controlled). Presence of certain other mucosal lesions, especially those that ... dissolving lozenges or mucosal gels; sometimes being used to treat various forms of stomatitis. Systemic corticosteroids may ...
*  Diethyl phthalate
... phthalate and ethanol after oral administration in the lumen of the gastrointestinal tract or in the intestinal mucosal cells. ... In rats, for instance, repeated administration of DEP results in loss of germ cell populations in the testis. However, diethyl ...
*  DNA vaccination
... and topical administration of pDNA to the eye and vaginal mucosa. Mucosal surface delivery has also been achieved using ... It can also be accomplished by the co-administration of plasmid DNA encoding immune regulatory molecules, i.e. cytokines, ... This concept was applied in topical administration of pDNA encoding IL-10. Plasmid encoding B7-1 (a ligand on APCs) ... The advantages of genetic adjuvants are their low cost and simple administration, as well as avoidance of unstable recombinant ...
*  Mucoadhesion
This route of administration is used for the therapy of bladder cancer and interstitial cystitis. The retention of dosage forms ... Some mucoadhesive materials are able to stick to mucosal lining in the bladder, resist urine wash out effects and provide a ... Consequently, direct administration through the fibrous tunic is common. This is made difficult due to the numerous defense ... With a 0.1-0.7 mm thick mucus layer, the oral cavity serves as an important route of administration for mucoadhesive dosages. ...
*  Tomatine
The oral administration of tomatine in doses of 15-30 mg/kg or the intramuscular administration in the dose range of 1-10 mg/kg ... In vitro studies showed that tomatine increased the permeability of the small intestinal mucosal cell, resulting in inhibition ... Oral administration of tomatine to frogs induces a cationic effect on cardiac contraction, producing symptoms of tachycardia. ... In a research on frogs, oral administration of low-concentration tomatine has a cationic effect on cardiac contractions. It is ...
*  Cetalkonium chloride
Distribution of cyclosporine A in ocular tissues after topical administration of cyclosporine A cationic emulsions to pigmented ... Mucosal delivery of biopharmaceuticals, Springer Science New York 2014 Daull P, Lallemand F, Philips B, Lambert G, Buggage R, ...
*  Sawdust
The Occupational Safety and Health Administration (OSHA) has set the legal limit (permissible exposure limit) for wood dust ... Breathing airborne wood dust may cause allergic respiratory symptoms, mucosal and non-allergic respiratory symptoms, and cancer ... the Occupational Safety and Health Administration (OSHA), and the National Institute for Occupational Safety and Health (NIOSH ... United Startes Department of Labor: Occupational Safety and Health Administration. Wood Dust. http://www.osha.gov/SLTC/wooddust ...
*  Troxipide
The increment in mucosal blood flow with troxipide is more pronounced in the gastric antrum than in the gastric corpus. ... Troxipide administration caused a marked reduction in clinical (abdominal pain, bloating, belching, nausea, vomiting, loss of ... Troxipide enhances mucosal blood flow, which is the secondary defense barrier of gastric mucosa that supplies nutrients and ... Matsui H, Murata Y, Kobayashi F, Shiba R, Momo K, Kondo Y, Nakahara A, Muto H (2001). "Diclofenac-induced gastric mucosal ...
*  Rebamipide
It is not approved by the Food and Drug Administration for use in the United States. Studies have shown that rebamipide can ... Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, is used for mucosal protection, healing of gastroduodenal ulcers, ... It works by enhancing mucosal defense, scavenging free radicals, and temporarily activating genes encoding cyclooxygenase-2. ... overview of its mechanisms of action and efficacy in mucosal protection and ulcer healing". Dig Dis Sci. 43 (9 Suppl): 5S-13S. ...
*  Camurus
episil is administered as a lipid-based liquid that spreads on the intra-oral mucosal surfaces and transforms to a strongly ... This analgesic effect was maintained over at least 8 hours following administration. The treatment was reported to be safe and ...
*  Immune tolerance
... allowing extension of mucosal immunity. The same probably occurs for cells mediating mucosal immune tolerance. Oral tolerance ... Repeated administration of the allergen in slowly increasing doses, subcutaneously or sublingually appears to be effective for ... Peripheral mucosal immune tolerance, in particular mediated by iTreg cells and tolerogenic antigen-presenting cells, is thought ... Repeated administration of antibiotics, which can form haptens to cause allergic reactions, can also reduce antibiotic ...
*  Bisphosphonate-associated osteonecrosis of the jaw
In response to the growing base of literature on this association, the United States Food and Drug Administration issued a ... Patients with removable prostheses should be examined for areas of mucosal irritation. Procedures which are likely to cause ... the risk for BRONJ is high even after stopping the administration of the medication for several years. Dentoalveolar surgery is ... Jaw pain and neuropathy Loose teeth Mucosal swelling Erythema Suppuration Soft tissue ulceration persisting for more than 8 ...
*  Influenza treatment
On October 23, the U.S. Food and Drug Administration (FDA) issued an Emergency Use Authorization for Peramivir (now expired), ... April 2006). "Type I IFN as a vaccine adjuvant for both systemic and mucosal vaccination against influenza virus". Vaccine. 24 ... CS1 maint: Multiple names: authors list (link) - see also "Systemic effects of interferons after oral administration in animals ... July 2008). "Effect of sublingual administration of interferon-alpha on the immune response to influenza vaccination in ...
*  Edible algae vaccine
IgA antibodies commonly reside in mucosal linings which coincides with the site of vaccine delivery. However, a significant ... Food and Drug Administration (2002) GRAS Notification for Spirulina Microalgae Specht, Elizabeth A.; Mayfield, Stephen P. " ... the completion of a market ready edible algae vaccine would have a profound impact in the administration and distribution of ... of a foot-and-mouth disease antigen complexed with the cholera toxin subunit B which delivered the antigen to digestion mucosal ...
*  Ulcerative colitis
The theory of sulfur as an etiological factor is related to the gut microbiota and mucosal sulfide detoxification in addition ... The goal is to induce remission initially with medications, followed by the administration of maintenance medications to ... Mahadeva U, Martin JP, Patel NK, Price AB (July 2002). "Granulomatous ulcerative colitis: a re-appraisal of the mucosal ... Physicians first direct treatment to inducing remission, which involves relief of symptoms and mucosal healing of the colon's ...
*  Ursula Wiedermann
A theme of Wiedermann's allergy research has been the treatment of allergies via mucosal tolerance induction with recombinant ... "Perinatal maternal administration of Lactobacillus paracasei NCC 2461 prevents allergic inflammation in a mouse model of birch ... After returning to the Medical University of Vienna Wiedermann researched mucosal vaccination against allergic diseases and ... Wiedermann U. (October 1, 2005). "Prophylaxis and therapy of allergy by mucosal tolerance induction with recombinant allergens ...
*  Gastrointestinal stromal tumor
The mucosal surface is usually intact except for areas of ulceration, which are generally present in 50% of GISTs. Ulcerations ... 5 cm), heterogeneous enhancement after contrast administration and ulcerations. Also, overtly malignant behavior (in ... Mucosal ulcerations may also be present. In contrast enhanced CT images, large GISTs appear as heterogeneous masses due to ... are high signal intensity on T2-weighted images and enhance after administration of gadolinium. Signal-intensity voids are ...
*  Nonsteroidal anti-inflammatory drug
Such damage occurs irrespective of the route of administration of the NSAID (e.g., oral, rectal, or parenteral) and can occur ... Recent studies show that over 50% of patients who take NSAIDs have sustained some mucosal damage to their small intestine. ... United States Food and Drug Administration. Retrieved 2017-03-08. "Information for Healthcare Professionals: Valdecoxib ( ... route of administration, and tolerability profile. Regarding adverse effects, selective COX-2 inhibitors have lower risk of ...
*  Peppermint
Medicinal uses of peppermint have not been approved as effective or safe by the US Food and Drug Administration. With caution ... High oral doses of peppermint oil (500 mg) can cause mucosal irritation and mimic heartburn. As an aroma, peppermint may have ... Menthol activates cold-sensitive TRPM8 receptors in the skin and mucosal tissues, and is the primary source of the cooling ...
*  Management of ulcerative colitis
If there is an abnormally large drop in white blood cell count, or any blood cell count, administration of the drug should be ... Physicians first direct treatment to inducing a remission which involves relief of symptoms and mucosal healing of the lining ... Frequent blood cell counts are also recommended during administration of mercaptopurine. The drug may be toxic to bone marrow, ... The goal is to induce remission initially with medications, followed by the administration of maintenance medications to ...
*  Interleukin
On the other hand, administration of recombinant IL-12 may have therapeutic benefit in conditions associated with pathological ... These functions may be particularly important in mediating the hematopoietic, osseous and mucosal protective effects of ...
*  2015 Queen's Birthday Honours (Australia)
... and to university leadership and administration. Finn Axel Pratt PSM - For distinguished service to public administration, to ... academic and researcher in the area of mucosal immunisation. Bulent Hass Dellal OAM, Vic - For distinguished service to the ... Sarah Jane Halton PSM - For distinguished service to public administration, particularly to the health and aged care sectors, ... Ross David Milbourne - For distinguished service to higher education, to academic leadership and administration, to the ...
*  Norovirus
Immunity Against Mucosal Pathogens. Springer. p. 232. ISBN 978-1-4020-8412-6. Robert Matthews. "I've lost my appetite.." New ... polymerase chain reaction are being employed by governmental laboratories such as the Food and Drug Administration (FDA) in the ...