Loading...
*  Nasal administration
Intranasal midazolam is found to be highly effective in acute episodes of seizures in children. Recently, the upper part of the ... Nasal administration is a route of administration in which drugs are insufflated through the nose. It can be a form of either ... Nasal administration can therefore be used as an alternative to oral administration of for example tablets and capsules if a ... the variability in the amount absorbed after nasal administration should be comparable to that after oral administration. The ...
*  Examorelin
Laron, Z.; Frenkel, J.; Deghenghl, R.; Anin, S.; Klinger, B.; Siibergeld, A. (1995). "Intranasal administration of the GHRP". ... Frenkel, J.; Silbergeld, A.; Deghenghi, R.; Laron, Z. (1995). "Short Term Effect of Intranasal Administration of Hexarelin". ... intranasal, and oral administration in man". J Clin Endocrinol Metab. 78 (3): 693-8. doi:10.1210/jcem.78.3.8126144. PMID ... "Short-term administration of intranasal or oral Hexarelin, a synthetic hexapeptide, does not desensitize the growth hormone ...
*  Oxytocin
... since intranasal administration of oxytocin also increases envy and Schadenfreude. Individuals who receive an intranasal dose ... Theodoridou A, Penton-Voak IS, Rowe AC (2013). "A direct examination of the effect of intranasal administration of oxytocin on ... Shamay-Tsoory SG, Fischer M, Dvash J, Harari H, Perach-Bloom N, Levkovitz Y (November 2009). "Intranasal administration of ... Fischer-Shofty M, Shamay-Tsoory SG, Harari H, Levkovitz Y (January 2010). "The effect of intranasal administration of oxytocin ...
*  Relationship counseling
Shamay-Tsoory SG, Fischer M, Dvash J, Harari H, Perach-Bloom N, Levkovitz Y (November 2009). "Intranasal administration of ... Some researchers have argued oxytocin has a general enhancing effect on all social emotions, since intranasal administration of ... 19 (7). Wudarczyk, O. A.; Earp, B. D.; Guastella, A; Savulescu, J (2013). "Could intranasal oxytocin be used to enhance ...
*  Estrogen (medication)
Rigg LA, Milanes B, Villanueva B, Yen SS (1977). "Efficacy of intravaginal and intranasal administration of micronized ... This route of administration is thus preferred in women with a history of thrombo-embolic disease. Estrogen is also used in the ... However, such risks have been found to vary depending on the type of estrogen or progestogen and the route of administration. ... It was only until 1941 when estrogen therapy was finally approved by the Food and Drug Administration (FDA) for the treatment ...
*  Oxytocin (medication)
Fischer-Shofty M, Shamay-Tsoory SG, Harari H, Levkovitz Y (2010). "The effect of intranasal administration of oxytocin on fear ... "Intranasal oxytocin administration is reflected in human saliva". Psychoneuroendocrinology. 37 (9): 1582-6. doi:10.1016/j. ... "Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration". Neuro ... Intranasal oxytocin has a central duration of at least 2.25 hours and as long as 4 hours. Oral: Oxytocin is destroyed in the ...
*  Jason Diamond
Comparing Intranasal Administration to Intramuscular Administration in Healthy Human Volunteers." University of Kentucky ... "A single dose, Open Label, Randomized Three Way Crossover, Bioavailability Study of 1.0 mg and 2.0 Intranasal Butorphanol ... "A single Dose, Randomized Two Period Crossover Pharmacokinetic Study of 2.0 mg Intranasal Hydromorphone Hydrochloride In ...
*  Methamphetamine
... is also well absorbed following inhalation and following intranasal administration. It is distributed to most ... Methamphetamine is also well absorbed following inhalation and following intranasal administration. Due to the high ... Repeated administration or self administration of METH has been shown to upregulate σ-1 receptor protein and mRNA in various ... The lack of effect of administration of neomycin to one patient indicates that the hydroxylation occurs in body tissues. ... a ...
*  Doxylamine
The bioavailability of doxylamine is 24.7% for oral administration and 70.8% for intranasal administration. The Tmax of ... "Comparative pharmacokinetics of single doses of doxylamine succinate following intranasal, oral and intravenous administration ... Doxylamine succinate is generally safe for administration to healthy adults. The median lethal dose (LD50) is estimated to be ...
*  Buserelin
Its bioavailability is 2.5 to 3.3% by intranasal administration and 70% by subcutaneous injection. The plasma protein binding ... With chronic administration of buserelin however, the GnRH receptor becomes desensitized and completely stops responding both ... The elimination half-life of buserelin regardless of route of administration is about 72 to 80 minutes. Buserelin and its ... Trabant H, Widdra W, de Looze S (1990). "Efficacy and safety of intranasal buserelin acetate in the treatment of endometriosis ...
*  NS1 influenza protein
Vincent AL, Ma W, Lager KM, Janke BH, Webby RJ, Garcia-Sastre A, Richt JA (2007). "Efficacy of intranasal administration of a ...
*  Selank
"Intranasal administration of the peptide Selank regulates BDNF expression in the rat hippocampus in vivo". Doklady Biological ...
*  Demyelinating disease
Clausi, M.G.; Paez, P.M.; Campagnoni, A.T.; Pasquini, L.A.; Pasquini, J.M.; Ahmadiani, A. (2012). "Intranasal administration of ... It has been shown that intranasal administration of aTf (apotransferrin) can protect myelin and induce remyelination. Much of ...
*  Oxytocin treatment for postpartum depression
Increased levels of OT can be found in salivary samples after intranasal administration of the neuropeptide. Salivary OT levels ... Weisman, O., Zagoory-Sharon, O., & Feldman, R. (2012). Intranasal oxytocin administration is reflected in human saliva. ... Intranasal (IN) administration, as opposed to more conventional routes, such as oral or intravenous infusion, offers an ... A review of 38 randomized and controlled trials suggests that short-term use of intranasal oxytocin appears to have few side- ...
*  Von Willebrand disease
Desmopressin is also available as a preparation for intranasal administration (Stimate) and as a preparation for intravenous ... Administration of the latter is also associated with increased risk of venous thromboembolic complications. Blood transfusions ... Administration of ethinylestradiol diminishes the secretion of luteinizing hormone and follicle-stimulating hormone from the ... administration. Recently, the FDA has approved the use of Baxalta's Vonvendi. This is the first recombinant form of vWF. The ...
*  Bio-MEMS
Some drugs, such as diazepam, are poorly soluble and need to be aerosolized immediately prior to intranasal administration. Bio ... From the user standpoint, microneedles can be incorporated into a patch format for self-administration, and do not constitute a ...
*  Biological half-life
In addition, also unlike the case of peripheral administration, intranasal oxytocin has a central duration of at least 2.25 ... "Intranasal oxytocin administration is reflected in human saliva". Psychoneuroendocrinology. 37 (9): 1582-6. doi:10.1016/j. ... "Salivary levels of oxytocin remain elevated for more than two hours after intranasal oxytocin administration". Neuro ... Thus the fall in plasma concentration after the administration of a single dose is described by the following equation: C t = C ...
*  Anosmia
Preventing Anosmia from Intranasal Zinc Administration[unreliable medical source?] Maruyama T, Yasuda S, Odashiro K, Kaji Y, ... Intranasal drug use Samter's triad also known as AERD (aspirin exacerbated respiratory disease) Foster Kennedy syndrome Cadmium ... On June 16, 2009, the US Food and Drug Administration sent a warning letter to Matrixx Initiatives, manufacturer of an over-the ... Sarcoidosis Zinc-based intranasal cold products, including remedies labelled as "homeopathic" Chronic atrophic rhinitis Paget's ...
*  Yakult
September 12, 2014). "Effect of Intranasal Administration ofLactobacillus casei Shirota on Influenza Virus Infection of Upper ...
*  Dennis S. Charney
... owns patents in dopamine and noradrenergic reuptake inhibitors in treatment of schizophrenia and in intranasal administration ... Member, Food and Drug Administration Psychopharmacologic Drug Advisory Committee Editorial Committee, Biological Psychiatry, a ...
*  Klebsiella pneumoniae
... or intranasal administration of phages in laboratory tests. Resistance to phages is not likely to be as troublesome as to ...
*  Let-7 microRNA precursor
Intranasal administration of let-7 has already been found effective in reducing tumor growth in a transgenic mouse model of ...
*  Remifentanil
Levine, A. I., & Bryson, E. O. (2010). Intranasal self-administration of remifentanil as the foray into opioid abuse by an ... Panlilio, L. V., & Schindler, C. W. (2000). Self-administration of remifentanil, an ultra-short acting opioid, under continuous ... Comparison of remifentanil or fentanyl administration during isoflurane anesthesia for coronary artery bypass surgery. Med Sci ... US Food and Drug Administration. (2010). Orange book: approved drug products with therapeutic equivalence evaluations. Silver ...
*  Hiccup
The administration of intranasal vinegar was found to ease the chronic and severe hiccups of a three-year-old Japanese girl. ... "食用酢の点鼻による吃逆の治療 Hiccup treated by administration of intranasal vinegar". No to Hattatsu. Brain and Development (in Japanese). 39 ... The Food and Drug Administration approved the vagus nerve stimulator in 1997 as a way to control seizures in some patients with ...
*  Pregnenolone
"Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration". Eur ... Unlike the case of oral administration, transdermal administration of 30 mg/day pregnenolone cream has not been found to affect ... Oral administration of 50 or 100 mg pregnenolone has been found to have minimal or negligible effect on urinary levels of ... In further research by their group, a single 400 mg dose of oral pregnenolone at 3 hours post-administration was found to ...
*  Oxycodone
... with rectal administration yielding the same results; intranasal varies between individuals with a mean of 46%. Taken orally, ... Therapeutic Goods Administration (June 2008). Standard for the uniform scheduling of drugs and poisons no. 23 (PDF). Canberra: ... Drug Enforcerment Administration. Retrieved 23 November 2015. "DEA Diversion Control CSA". US Dept of Justice - DEA. Retrieved ... In the United Kingdom, it is available in 10 mg/mL and 50 mg/mL formulation for intramuscular or intravenous administration. ...
*  Allopregnanolone
"Brain distribution and behavioral effects of progesterone and pregnenolone after intranasal or intravenous administration". Eur ... In accordance, acute administration of low doses of micronized progesterone (which reliably elevates allopregnanolone levels), ... "Investigations on changes in ¹³C/¹²C ratios of endogenous urinary steroids after pregnenolone administration". Drug Test Anal. ... "Urinary marker of oral pregnenolone administration". Steroids. 70 (3): 179-83. doi:10.1016/j.steroids.2004.12.007. PMID ...