... gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions". EMBO J ...
SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination. - ... Nasomaxillary dysplasia is caused by a development arrest at the junction of the lateral side of the nose and the maxilla, ...
Ham C, Levkau B, Raines EW, Herren B (2002). "ADAM15 is an adherens junction molecule whose surface expression can be driven by ...
Yoon M, Spear PG (2002). "Disruption of Adherens Junctions Liberates Nectin-1 To Serve as Receptor for Herpes Simplex Virus and ... is an adhesion molecule found in a wide range of tissues where it localizes in various junctions such as the adherens junction ... An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a ... An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a ...
"Leptospira interrogans causes quantitative and morphological disturbances in adherens junctions and other biological groups of ...
"A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata ... Additionally, plakophilin-2 was found in adherens junctions of cardiac myxomata tumors analyzed, and absent in patients with ... couple the assembly of adherens junctions to the translocation of desmosome precursors in newly formed cell-cell junctions. ... Plakophilin-2 over time has shown to be more than components of cell-cell junctions; rather the plakophilins are emerging as ...
... is a target gene for vezatin, an adherens junctions transmembrane protein, which is a tumor suppressor in gastric cancer ...
In the nonpolar inner cells, AMOT localizes to adherens junctions (AJs), and Ser-176 at the N-terminal domain is phosphorylated ... In the outer cells, the cell polarity sequesters AMOT from basolateral adherens junctions to apical domains, thereby ... In primary endothelial of Chinese hamster ovary, it localizes to cell-cell junction, recruits ZO-1 and interacts with MAGI-1. ... It localizes to cell-cell junction like p80 and regulates paracellular permeability. Its N-terminal domain localizes to actin ...
... to-cell adherens junction: purification and characterization". J. Cell Biol. 108 (6): 2369-82. doi:10.1083/jcb.108.6.2369. PMC ...
They are similar in function and structure to the zonula adherens or adherens junction of epithelial cells. It is a broad ... In anatomy for cardiac muscle, fascia adherens are ribbon-like structures that stabilize non-epithelial tissue. ... intercellular junction in the transversal sections of an intercalated disc of cardiac muscle anchoring actin filaments. It ...
Of the three types of anchoring junctions, only two are involved in cell-cell interactions: adherens junctions and desmosomes. ... Adherens junctions are made of cell adhesion molecules from the cadherin family. There are over 100 types of cadherins, ... In the adherens junctions of epithelial cells, E-cadherin is the most abundant. Desmosomes also provide strength and durability ... Adjacent epithelial cells are connected by adherens junctions on their lateral membranes. They are located just below tight ...
This transition occurs through the loss of epithelial cadherin, tight junctions, and adherens junctions on the cell membranes ...
Translocation of β-catenin from adherens junctions to the nucleus may lead to a loss of E-cadherin and subsequently to EMT. ... EMT's important feature is the loss of membrane E-cadherin in adherens junctions, where β-catenin may play a significant role. ...
... where they commonly stabilize cell-cell junctions known as adherens junctions. Cadherins stabilize adherens junctions through ... to stabilize E-cadherin-based adherens junctions. PTPmu also dephosphorylates another cell junction protein, connexin 43. The ... a protein that is also localized to adherens junctions. Although p120 catenin is a potential substrate of PTPmu, others have ... Caveolin 1 is a scaffolding protein enriched in endothelial cell junctions that is also linked to shear stress regulated ...
... epithelial cells adhere to one another as well as the hyaline layer through classic cadherins and adherens junctions. ...
"Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin ...
Lehtonen S, Lehtonen E, Kudlicka K, Holthöfer H, Farquhar MG (Sep 2004). "Nephrin forms a complex with adherens junction ...
... intermediate filaments have the ability to help with vascular permeability through organizing continuous adherens junctions ...
... c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions ...
... fascia adherens junctions, and gap junctions. Fascia adherens are anchoring sites for actin, and connect to the closest ... All of these junctions work together as a single unit called the area composita. Mutations in the intercalated disc gene are ... Gap junctions connect the cytoplasms of neighboring cells electrically allowing cardiac action potentials to spread between ... The three types of cell junction recognised as making up an intercalated disc are desmosomes, ...
Laprise P, Viel A, Rivard N (2004). "Human homolog of disc-large is required for adherens junction assembly and differentiation ...
The junctions between the epidermal cells are of the adherens junction type, formed by transmembrane proteins called cadherins ... Because of the proximity of the neighboring cells and tightness of the junctions, the actin immunofluorescence appears as a ... Characteristics Physical barrier: Epidermal keratinocytes are tightly linked by cell-cell junctions associated to cytoskeletal ...
p0071 binds E-cadherin at adherens junctions, which are important for maintenance of cell architecture in epithelial tissues, ... interacts with the adherens junction protein p0071 to regulate cell-cell adhesion". PLOS ONE. 7 (11): e47842. Bibcode:2012PLoSO ...
Adherens junctions are also reduced due to bradykinin B1 and B2 receptor activation and vascular endothelial growth factor ( ... The degradation of these endothelial intercellular barrier junctions mediated by histamine leads to increased vascular ...
2004). "Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation ...
... and is mainly located in adherens junctions. Its tumor suppressor properties are probably associated with contact-mediated ...
Mariner DJ, Wang J, Reynolds AB (2000). "ARVCF localizes to the nucleus and adherens junction and is mutually exclusive with ... is a member of the catenin family which play an important role in the formation of adherens junction complexes, which are ... "The armadillo repeat region targets ARVCF to cadherin-based cellular junctions". J. Cell Sci. 113 (22): 4121-35. doi:10.1242/ ... "The armadillo repeat region targets ARVCF to cadherin-based cellular junctions". J. Cell Sci. 113 (22): 4121-35. doi:10.1242/ ...
... α-catenin and β-catenin in pancreatic acinar cells prior to the dissolution of adherens junctions in a rat model of ... "Protein tyrosine phosphatase kappa and SHP-1 are involved in the regulation of cell-cell contacts at adherens junctions in the ... at the plasma membrane in association with the cadherin/catenin complex is important for the maintenance of adherens junction ...
Intercalated discs are composed of gap junctions, adherens junctions and desmosomes, and are critical for the mechanical and ... Deficiency of LIMP-2 in mice was also reported to impair cell membrane transport processes and cause pelvic junction ... "LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice". Human ... "LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice". Human ...
... and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of ... Funke L, Dakoji S, Bredt DS (2005). "Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions ...