... , subfamily InterPro: IPR006259 UMP-CMP kinase InterPro: IPR006266 Adenylate kinase, isozyme 1 InterPro: ... In mutated Escherichia coli that had a disrupted nucleoside diphosphate kinase, adenylate kinase performed dual enzymatic ... In mutated Escherichia coli that had a disrupted nucleoside diphosphate kinase, adenylate kinase performed dual enzymatic ... Lu Q, Inouye M (June 1996). "Adenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolism". ...

... is a protein that in humans is encoded by the AK1 gene. This gene encodes an adenylate kinase enzyme ... "Entrez Gene: Adenylate kinase 1". Retrieved 2018-10-13. Corrons JL, Garcia E, Tusell JJ, Varughese KI, West C, Beutler E (July ... Fulvia GB, Antonio P, Anna N, Patrizia S, Ada A, Egidio B, Andrea M (December 2011). "Adenylate kinase locus 1 polymorphism and ... "Red cell adenylate kinase deficiency: molecular study of 3 new mutations (118G>A, 190G>A, and GAC deletion) associated with ...

In enzymology, a nucleoside-triphosphate-adenylate kinase (EC 2.7.4.10) is an enzyme that catalyzes the chemical reaction ... Other names in common use include guanosine triphosphate-adenylate kinase, nucleoside triphosphate-adenosine monophosphate ... and isozyme 3 of adenylate kinase. This enzyme participates in pyrimidine metabolism. As of late 2007, two structures have been ...

"Ancient divergence of long and short isoforms of adenylate kinase: molecular evolution of the nucleoside monophosphate kinase ... Byeon L, Shi Z, Tsai MD (March 1995). "Mechanism of adenylate kinase. The "essential lysine" helps to orient the phosphates and ... Dreusicke D, Schulz GE (November 1986). "The glycine-rich loop of adenylate kinase forms a giant anion hole". FEBS Letters. 208 ... Müller CW, Schulz GE (March 1992). "Structure of the complex between adenylate kinase from Escherichia coli and the inhibitor ...

Adenylate kinase 3 is a protein that in humans is encoded by the AK3 gene. The protein encoded by this gene is a GTP:ATP ... "Entrez Gene: Adenylate kinase 3". Retrieved 2017-05-19. PDBe-KB provides an overview of all the structure information available ...

SLC40A1 Hemolytic anemia due to adenylate kinase deficiency; 612631; AK1 Hemolytic anemia due to gamma-glutamylcysteine ... response to tyrosine kinase inhibitor in; 211980; EGFR Nonsmall cell lung cancer, somatic; 211980; IRF1 Nonsmall cell lung ... response to tyrosine kinase inhibitor in; 211980; EGFR Adenocarcinoma of lung, somatic; 211980; BRAF Adenocarcinoma of lung, ... GALNT3 Tyrosine kinase 2 deficiency; 611521; TYK2 Tyrosinemia type II; 277660; TAT Tyrosinemia type III; 276710; HPD Ullrich ...

"Identification of a novel adenylate kinase system in the brain: cloning of the fourth adenylate kinase". Brain Res. Mol. Brain ... Adenylate kinase isoenzyme 4, mitochondrial is an enzyme that in humans is encoded by the AK4 gene. This gene encodes a member ... of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases ... Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and ...

KP6107 by screening based on adenylate kinase assay". Journal of Basic Microbiology. 53 (7): 581-9. doi:10.1002/jobm.201200045 ...

Kaur H, Lakatos-Karoly A, Vogel R, Nöll A, Tampé R, Glaubitz C (2016). "Coupled ATPase-adenylate kinase activity in ABC ... on real-time 31P-MAS-NMR they found that the homodimeric lipid A flippase MsbA is able to catalyze a reverse adenylate kinase- ... The kinase Tbk1 was identified as important for mediating optineurin based xenophagy to remove the bacteria from the infected ... "The leukemogenic AF4-MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures". Leukemia. 25 (1): ...

KP6107 by screening based on adenylate kinase assay". Journal of Basic Microbiology. 53 (7): 581-9. doi:10.1002/jobm.201200045 ...

Rose, I.A. (1968). "State of magnesium in cells as estimated from adenylate kinase equilibrium". Proc. Natl. Acad. Sci. USA. 61 ... and studied it on the basis of the equilibrium of the reaction catalyzed by adenylate kinase, a complicated question, because ... Rose, I.A. (1970). "Stereochemistry of pyruvate kinase, pyruvate carboxylase, and malate enzyme reactions". J. Biol. Chem. 245 ... Rose, Irwin A. (1955). "Acetate kinase of bacteria (acetokinase)". Methods Enzymol. 1: 591-595. doi:10.1016/0076-6879(55)01102- ...

Vieille C; Krishnamurthy H; Hyun HH; Savchenko A; Yan H; Zeikus JG (June 2003). "Thermotoga neapolitana adenylate kinase is ...

... has been found to interact with Adenylate Kinase 2, Artemin, and Importin 13. The human protein has two isoforms and no ...

Townley R, Shapiro L (March 2007). "Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase ... These standalone CBS domain proteins might form complexes upon binding to other proteins such as kinases to which they interact ... voltage gated chloride channels and AMP-activated protein kinase (AMPK). CBS domains regulate the activity of associated ... "Structural basis for AMP binding to mammalian AMP-activated protein kinase". Nature. 449 (7161): 496-500. doi:10.1038/ ...

... is caused by mutations in the gene encoding mitochondrial adenylate kinase 2". Nature Genetics. 41 (1): 101-105. doi:10.1038/ng ...

The quick energy sources consist of the phosphocreatine (PCr) system, fast glycolysis, and adenylate kinase. All of these ... but the most readily depleted of the above sources is the PCr system which utilizes the enzyme creatine kinase. This enzyme ... resource is short lasting because oxygen is required for the resynthesis of phosphocreatine via mitochondrial creatine kinase. ...

Gao, Yongxiang (November 2013). "Crystallization and preliminary X-ray diffraction analysis of MJ0458, an adenylate kinase from ...

... is produced from DNA by the action of nuclease P1, adenylate kinase, and pyruvate kinase. High ... "Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases". ...

"The crystal structure of phosphoribulokinase from Rhodobacter sphaeroides reveals a fold similar to that of adenylate kinase". ... 5-phosphoribulose kinase, ribulose phosphate kinase, PKK, PRuK, and PRK. Berg, Jeremy M.; Tymoczko, John L.; Gatto, Jr., ... The RsPRK subunit exhibits a protein folding analogous to the folding of nucleotide monophosphate (NMP) kinases. Mutagenesis ... Miziorko HM, Eckstein F (November 1984). "The stereochemical course of the ribulose-5-phosphate kinase-catalyzed reaction". The ...

... mitochondrial creatine kinase and adenylate translocator display properties of the permeability transition pore. Implication ... for regulation of permeability transition by the kinases". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1368 (1): 7-18. ...

Superoxide dismutase, malate dehydrogenase (decarboxylating), ferredoxin, adenylate kinase and NADH:ferredoxin oxido-reductase ...

The three adenylates are related by the reaction catalysed by adenylate kinase: ATP + AMP ↽ − − ⇀ 2 ADP {\displaystyle {\ce { ... Atkinson, D. E. (1968). "The energy charge of the adenylate pool as a regulatory parameter: Interaction with feedback modifiers ... but the case of the adenylates is more complicated, as there are three components to be considered, AMP, ADP and ATP. ... as a way to rationalize the dependence of metabolic processes on the proportions of the adenylates. For pairs of metabolites, ...

"Characterization of human adenylate kinase 3 (AK3) cDNA and mapping of the AK3 pseudogene to an intron of the NF1 gene". ...

Ammonia levels may rise given ammonia is a by-product of the adenylate kinase pathway, an alternative pathway for ATP ... adenylate kinase) reaction, which also runs when the ATP reservoir is low. The myokinase reaction is one of three reactions in ... The enzyme phosphorylase kinase plays a role in phosphorylating glycogen phosphorylase to activate it and another enzyme, ... This is due to the lack of normal pH fall during exercise, which impairs the creatine kinase equilibrium and exaggerates the ...

Since the adenylate kinase maintains two ADP molecules in equilibrium with one ATP ( 2 ADP ↽ − − ⇀ ATP + AMP {\displaystyle {\ ... Chapman AG, Atkinson DE (December 1973). "Stabilization of adenylate energy charge by the adenylate deaminase reaction". The ... and by adenylate kinase, an enzyme that maintains the three adenine nucleotides in equilibrium ( ATP + AMP ↽ − − ⇀ 2 ADP {\ ... The adenylate energy charge is an index used to measure the energy status of biological cells. ATP or Mg-ATP is the principal ...

Van Rompay AR, Johansson M, Karlsson A (1999). "Identification of a novel human adenylate kinase. cDNA cloning, expression ... Adenosine kinase is an enzyme that in humans is encoded by the ADK gene. This gene encodes adenosine kinase, an abundant enzyme ... Spychala J, Datta NS, Takabayashi K, Datta M, Fox IH, Gribbin T, Mitchell BS (Mar 1996). "Cloning of human adenosine kinase ... Singh B, Lin A, Wu ZC, Gupta RS (2001). "Gene structure for adenosine kinase in Chinese hamster and human: high-frequency ...

This is due to the basic pH in the stroma, where the reaction occurs, as well as high concentrations of adenylate kinase and ... However, pyruvate kinase catalyses an irreversible reaction, and does not consume ATP. By contrast, PPDK catalyses a reversible ... Research has shown that the PPDK binding mechanisms are similar to that of D-Ala-D-Ala ligase and pyruvate kinase. In ... Evolutionary history suggests that it once had a role in glycolysis like the similar pyruvate kinase, and eventually evolved ...

... α2 receptors inhibit adenylate cyclase (via Gi), decreasing the activity of protein kinase A (PKA); β receptors activate ... The G-protein receptor can affect the function of adenylate cyclase or phospholipase C, an agonist of the receptor will ... increasing the activity of protein kinase C (PKC); ... adenylate cyclase (via Gs), thus increasing the activity of PKA ...

... adenylate kinase) reaction and purine nucleotide cycle. Amino acids are vital to the purine nucleotide cycle as they are ...

... adenylate kinase) reaction and purine nucleotide cycle. Amino acids are vital to the purine nucleotide cycle as they are ...

In enzymology, a (deoxy)adenylate kinase (EC 2.7.4.11) is an enzyme that catalyzes the chemical reaction ATP + dAMP ⇌ {\ ... Griffith TJ, Helleiner CW (1965). "The partial purification of deoxynucleoside monophosphate kinases from L cells". Biochim. ...

"Entrez Gene: AK2 adenylate kinase 2". Bruns GA, Regina VM (1977). "Adenylate kinase 2, a mitochondrial enzyme". Biochem. Genet ... 1998). "Cloning and expression of human adenylate kinase 2 isozymes: differential expression of adenylate kinase 1 and 2 in ... Adenylate kinase 2 is an enzyme that is encoded in humans by the AK2 gene. The AK2 protein is found in the intermembrane space ... Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. ...

AMP is produced after strenuous muscle contraction when the ATP reservoir is low (ADP > ATP) by the adenylate kinase (myokinase ... Without this enzyme, the excessive AMP buildup is initially due to the adenylate kinase (myokinase) reaction which occurs after ... During strenuous exercise, AMP is created through the use of the adenylate kinase (myokinase) reaction after the phosphagen ... catalyzed by adenylate kinase/myokinase when CP is depleted, ATP is again used for muscle contraction) Muscle at rest: ATP + ...

Similarly, nucleoside-monophosphate kinase carries out the phosphorylation of nucleoside-monophosphates. Adenylate kinase is a ... AMP and GMP can then be converted into ATP and GTP, respectively, by kinases that add additional phosphates. ATP stimulates ... is catalyzed by nucleoside diphosphate kinase, which uses ATP as the phosphate donor. ... specific nucleoside-monophosphate kinase that functions only on adenosine-monophosphate. Carbohydrate metabolism DNA Nucleic ...

1989). "Regional assignment of the loci for adenylate kinase to 9q32 and for alpha 1-acid glycoprotein to 9q31-q32. A locus for ...