Infection can spread to humans. There are several fungal diseases that are systemic in nature, meaning they are affecting ... using canine adenovirus type 2 to avoid reaction). The decision on whether to vaccinate against other diseases, including ... Diseases that can be transmitted from animals to humans are termed zoonoses. A well-known zoonosis is rabies, a viral infection ... opportunistic infections secondary to decreased resistance (often the result of viral infections), or secondary to other ...

This process REQUIRES the use of an adenovirus for the DNA to enter the cell and cause infection, thus being stably integrated ... Human Gene Therapy McGill University Dean's Honors' list Chatterjee has made contributions in 38 publications, on many of which ... Adenovirus' have a Baltimore classification of level I, meaning that they have a liner dsDNA genome within an icosahedral ... replication-defective nonpathogenic human parvovirus with a 4.7kb DNA genome with a palindromic inverted terminal repeats" ...

... two viral vectors which safely mimic viral infection in human cells and elicit antibody and T cell responses to pathogens and ... The company's platform includes Chimpanzee Adenovirus Oxford (ChAdOx) and Modified Vaccinia Ankara (MVA), ... randomised controlled trial in five trial sites in the UK of a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) ...

Kadaveru K, Vyas J, Schiller MR (May 2008). "Viral infection and human disease--insights from minimotifs". Frontiers in ... the Adenovirus protein E1A. Pathogenic bacteria also mimic host motifs (as well as having their own motifs), however, not to ... A Dynein Light Chain binding motif in Rabies virus is vital for host infection). The extent of human SLiM mimicry is surprising ... Viruses often mimic human SLiMs to hijack and disrupt a host's cellular machinery, thereby adding functionality to their ...

The majority of work on adenovirus transcription has focused on human adenovirus, specifically Ad2 and Ad5. The complete ... After viral infection, they stimulate expression of other viral genes and can either enhance or repress expression of cellular ... Ad5 refers to a specific group of human adenoviruses. In Ad5-infected cells, E1A translation was hypothesized to involve the ... Hendrickx R, Stichling N, Koelen J, Kuryk L, Lipiec A, Greber UF (April 2014). "Innate immunity to adenovirus". Human Gene ...

... adenoviruses, and human parainfluenza viruses). Less common causes of ILI include bacteria such as Legionella, Chlamydia ... Influenza, RSV, and certain bacterial infections are particularly important causes of ILI because these infections can lead to ... Influenza in humans is subject to clinical surveillance by a global network of more than 110 National Influenza Centers. These ... During the 2009 flu pandemic in the United States, the CDC advised physicians to "consider swine influenza infection in the ...

Atkinson, R L; Dhurandhar, N V; Allison, D B; Bowen, R L; Israel, B A; Albu, J B; Augustus, A S (2004). "Human adenovirus-36 is ... JC Virus and Simian Virus 40 Infection in Humans, and Association with Human Tumors". Polyomaviruses and Human Diseases. ... Atkinson, Richard L.; Lee, Insil; Shin, Hye-Jung; He, Jia (2010). "Human adenovirus-36 antibody status is associated with ... Bode, L; Ludwig, H (2003). "Borna disease virus infection, a human mental-health risk". Clinical Microbiology Reviews. 16 (3): ...

... adenoviruses, rhinovirus, respiratory syncytial virus, human metapneumovirus, Bordetella pertussis, pneumococci, streptococcus ... "Principles of Epidemiology: Chain of Infection". U.S. Centers for Disease Control and Infection. 18 February 2019. Retrieved 21 ... Two routes are considered to be airborne: Airborne infections and droplet infections.[citation needed] "Airborne transmission ... in genital infections and the increased incidence of the type 2 virus (more common genitally) in oral infections.[citation ...

... science.org Efficacy of a virus-vectored vaccine against human and bovine respiratory syncytial virus infections, science,org A ... ilsole24ore.com Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation, nature.com ... 2002). "The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus". The EMBO Journal ... 2012). "Novel Adenovirus-Based Vaccines Induce Broad and Sustained T Cell Responses to HCV in Man". Science Translational ...

Specimens of nine children had human coronavirus HKU1. These children had respiratory tract infections at the time the ... and adenovirus by direct immunofluorescence assay as well as human metapneumovirus and HCoV-NH by reverse transcription ... HCoV-HKU1 is one of seven known coronaviruses to infect humans. The other six are: Human coronavirus 229E (HCoV-229E) Human ... Human coronavirus HKU1 (HCoV-HKU1) is a species of coronavirus in humans and animals. It causes an upper respiratory disease ...

... others caused by adenoviruses, human parainfluenza viruses, human respiratory syncytial virus, enteroviruses other than ... Sinus Infection And Allergic Rhinitis Specialist Library for ENT and Audiology Hay fever resources - online library of high ... Rhinitis is commonly caused by a viral or bacterial infection, including the common cold, which is caused by Rhinoviruses, ... In the case of infectious rhinitis, vaccination against influenza viruses, COVID-19 virus, adenoviruses, measles, rubella, ...

Since humans commonly come in contact with adenoviruses, which cause respiratory, gastrointestinal and eye infections, majority ... To overcome this problem scientists are currently investigating adenoviruses that infect different species to which humans do ... PEGylation of adenoviruses for gene therapy can help prevent adverse reactions due to pre-existing adenovirus immunity. Adeno- ... Seregin SS, Amalfitano A (2009). "Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based ...

... others caused by adenoviruses, human parainfluenza viruses, human respiratory syncytial virus, enteroviruses other than ... Generally sinusitis starts off as a common viral infection like common cold. This infection generally subsides within 5 to 7 ... An infection that lasts between four and 12 weeks, and represents a transition between acute and chronic infection. Chronic ... Infection of the eye socket is a rare complication of ethmoid sinusitis, which may result in the loss of sight and is ...

... and solar radiation as well as human behavior. Airborne infections usually land in the respiratory system, with the agent ... adenovirus, and possibly respiratory syncytial virus. Some pathogens which have more than one mode of transmission are also ... Preferential airborne infections, such as chicken pox, can be obtained through different routes, but mainly by aerosols. ... Obligate airborne infections spread only through aerosols; the most common example of this category is tuberculosis. ...

November 2020). "The Human Adenovirus Type 2 Transcriptome: An Amazing Complexity of Alternatively Spliced mRNAs". Journal of ... The additional primary transcript produced late in infection is large and comes from 5/6 of the 32kb adenovirus genome. This is ... By using next generation sequencing technology, researchers were able to update the human adenovirus type 2 transcriptome, and ... Research based on the Human Genome Project and other genome sequencing has shown that humans have only about 30% more genes ...

November 2003). "Adenovirus-mediated suicide gene therapy using the human telomerase catalytic subunit (hTERT) gene promoter ... combining the use of antisense hTERT sequences with the introduction of a tumor-suppressing plasmid by adenovirus infection ... Similarly, human TERT expression did not arrest epigenetic aging in human fibroblasts. The hTERT gene has become a main focus ... following retroviral transduction of human cord blood CD34+ cells with human telomerase reverse transcriptase". Haematologica. ...

"Antiviral effect of Bosentan and Valsartan during coxsackievirus B3 infection of human endothelial cells". The Journal of ... "Genomic organization and chromosomal localization of the human Coxsackievirus B-adenovirus receptor gene". Human Genetics. 105 ... Coxsackievirus and adenovirus receptor (CAR) is a protein that in humans is encoded by the CXADR gene. The protein encoded by ... Tomko RP, Xu R, Philipson L (Apr 1997). "HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and ...

"Immune responses to adenovirus and adeno-associated virus in humans". Gene Therapy. 6 (9): 1574-1583. doi:10.1038/sj.gt.3300994 ... Hernandez YJ, Wang J, Kearns WG, Loiler S, Poirier A, Flotte TR (October 1999). "Latent adeno-associated virus infection ... The adeno-associated virus serotype 1 (AAV1) viral vector delivers an intact copy of the human lipoprotein lipase (LPL) gene to ... their findings were featured on the September 2004 cover of Human Gene Therapy. Ross and Hayden next succeeded in treating cats ...

Unsurprisingly, sialic acids also play an important role in several human viral infections. The influenza viruses have ... "Human adenovirus type 26 uses sialic acid-bearing glycans as a primary cell entry receptor". Science Advances. 5 (9): eaax3567 ... In humans the brain has the highest sialic acid content, where these acids play an important role in neural transmission and ... Wang, B.; Brand-Miller, J. (2003). "The role and potential of sialic acid in human nutrition". European Journal of Clinical ...

Foxman, Ellen F.; Iwasaki, Akiko (1 April 2011). "Genome-virome interactions: examining the role of common viral infections in ... adenovirus, HIV, HTLV, hepatitis B, hepatitis C, parvovirus B19, and influenza virus). Of possible relevance to transfusion ... The human virome is the total collection of viruses in and on the human body. Viruses in the human body may infect both human ... Diverse viruses colonize the human skin and differ by skin site. This skin virome includes human viruses (i.e. human ...

... studying how SIV causes infection in animals, which provided insights on the spread of HIV and AIDS in humans. A widely ... gene therapy in which working copies of genes can be implanted into the human body by way of genetically modified adenoviruses ... Ginsberg showed the process by which the adenovirus caused disease after entering host cells, leading to the creation of ... He was on the faculty of Western Reserve University starting in 1951, where research he conducted showed that adenoviruses, ...

Kladney RD, Tollefson AE, Wold WS, Fimmel CJ (September 2002). "Upregulation of the Golgi protein GP73 by adenovirus infection ... v t e (Articles with short description, Short description matches Wikidata, Genes on human chromosome 9, All stub articles, ... Such cases of cirrhosis are usually due to infection caused by infectious hepatitis (usually hepatitis B or hepatitis C, though ... The expression of this encoded protein has been observed to be upregulated in response to viral infection. Golgi membrane ...

Using an adenovirus vector for wild-type p53, human ovarian cancer cell line 2774qw1 (which expresses mutant p53) was ... A 3.6 fold decrease of survivin mRNA level was observed 16 hours after infection initiation and decreased 6.7 fold 24 hours ... human lung cancer cell line with wild-type p53) and T47D (human breast cancer cell line with mutant p53) cells with DNA- ... The human IAPs, XIAP, c-IAPl, C-IAP2 have been shown to bind to caspase-3 and -7, which are the effector caspases in the ...

OPTN human gene location in the UCSC Genome Browser. OPTN human gene details in the UCSC Genome Browser. (Articles with short ... "Salmonella infection data for Optn". Wellcome Trust Sanger Institute. "Citrobacter infection data for Optn". Wellcome Trust ... Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to ... Optineurin is a protein that in humans is encoded by the OPTN gene. This gene encodes the coiled-coil containing protein ...

... of all infectious cases and can be a feature of many different types of viral infections. Adenovirus is the most common of the ... A number of different bacteria can infect the human throat. The most common is group A streptococcus (Streptococcus pyogenes), ... Most cases are caused by a viral infection. Strep throat, a bacterial infection, is the cause in about 25% of children and 10% ... Antibiotics are useful if a bacterial infection is the cause of the sore throat. For viral infections, antibiotics have no ...

"Human Adenovirus E Genome". NCBI. Retrieved 2013-01-17. "Human adenovirus E overview". NCBI. Retrieved 2013-01-17. " ... and in suppression of the host response to infection. The L1-L5 transcription units are transcribed later in the viral ... "Protein Details for Human adenovirus E". NCBI. Retrieved 2013-01-17. Russell, WC (Jan 2009). "Adenoviruses: update on structure ... The example used for the following description is Human adenovirus E, a mastadenovirus with a 36 Kbp genome containing 38 ...

... s also play a role in human immunodeficiency virus (HIV) infection. Like T cells, macrophages can be infected with ... Adenovirus (most common cause of pink eye) can remain latent in a host macrophage, with continued viral shedding 6-18 months ... Macrophages are better able to resist infection by HIV-1 than CD4+ T cells, although susceptibility to HIV infection differs ... "Macrophages and their relevance in Human Immunodeficiency Virus Type I infection". Retrovirology. 9 (1): 82. doi:10.1186/1742- ...

Infections occur more commonly during the winter. These infections have existed throughout human history. The typical symptoms ... Other commonly implicated viruses include human coronaviruses (≈ 15%), influenza viruses (10-15%), adenoviruses (5%), human ... It is estimated that sinusitis occurs in 8% and ear infection in 30% of cases. The common cold is the most common human disease ... Secondary bacterial infections may occur resulting in sinusitis, pharyngitis, or an ear infection. ...

AD-36 infection can induce cellular differentiation of 3T3-L1 preadipocytes and stem cells derived from human adipose tissue. ... Human adenovirus 36 (HAdV-36) or Ad-36 or Adv36 is one of 52 types of adenoviruses known to infect humans. AD-36, first ... To date, AD-36 is the only human adenovirus that has been linked with human obesity, present in 30% of obese humans and 11% of ... 2007). "Human adenovirus Ad-36 induces adipogenesis via its E4 orf-1 gene". Int J Obes (Lond). 32 (3): 397-406. doi:10.1038/sj. ...

A common helper virus in humans is the adenovirus.[citation needed] Dependoparvovirus is not infectious enough to trigger an ... does not stimulate an immune response it can be used multiple times effectively without being neutralized before infection[ ... Viral vectors are currently being developed to transport genes into human cells. Since this virus ... they cannot replicate productively in their host cell without the cell being coinfected by a helper virus such as an adenovirus ...