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*  Adenosine receptor
The adenosine receptors (or P1 receptors) are a class of purinergic G protein-coupled receptors with adenosine as endogenous ... Most older compounds acting on adenosine receptors are nonselective, with the endogenous agonist adenosine being used in ... Br J Pharmacol 170(6):1167-1176 "Entrez Gene: ADORA2A adenosine A2A receptor". Jacobson KA, Gao ZG (2006). "Adenosine receptors ... The adenosine A1 receptor has been found to be ubiquitous throughout the entire body. This receptor has an inhibitory function ...
*  Strimvelis
... a rare disorder caused by the absence of an essential protein called adenosine deaminase (ADA), which is required for the ... a committee at the European Medicines Agency recommended marketing approval for its use in children with adenosine deaminase ... replicating and creating cells that mature and create normally functioning adenosine deaminase protein, resolving the problem. ... Severe Combined Immunodeficiency due to Adenosine Deaminase deficiency), ...
*  ADAR
"Entrez Gene: ADAR Adenosine Deaminase Acting on RNA". Samuel CE (2012). Adenosine deaminases acting on RNA (ADARs) and A-to-I ... which stands for adenosine deaminase acting on RNA). Adenosine deaminases acting on RNA (ADAR) are enzymes responsible for ... Adenosine Deaminase Acting on RNA is one of the most common forms of RNA editing, and has both selective and non-selective ... Adenosine Deaminase Acting on RNA (ADAR) and its gene were first discovered accidentally in 1987 as a result of research by ...
*  Adenosine A2A receptor
The adenosine A2A receptor, also known as ADORA2A, is an adenosine receptor, and also denotes the human gene encoding it. This ... As a result, Adenosine receptor A2A decreases activity in the Dopamine D2 receptors. The adenosine A2A receptor has also been ... "Entrez Gene: ADORA2A adenosine A2A receptor". Ohta A, Sitkovsky M (2001). "Role of G-protein-coupled adenosine receptors in ... Older research on adenosine receptor function, and non-selective adenosine receptor antagonists such as aminophylline, focused ...
*  Adenosine A3 receptor
The adenosine A3 receptor, also known as ADORA3, is an adenosine receptor, but also denotes the human gene encoding it. ... 1997). "Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 ... a novel specific adenosine A(3) receptor antagonist with adenosine A(3) receptor agonists both in vitro and in vivo". Eur. J. ... a novel ligand that demonstrates both adenosine A(2A) receptor agonist and adenosine A(3) receptor antagonist activity". ...
*  Adenosine deaminase deficiency
The enzyme adenosine deaminase is encoded by a gene on chromosome 20. ADA deficiency is inherited in an autosomal recessive ... Adenosine deaminase deficiency (also called ADA deficiency or ADA-SCID) is an autosomal recessive metabolic disorder that ... "Adenosine Deaminase (ADA) Deficiency". Archived from the original on 12 February 2008. Retrieved 2008-02-28. p347, The Immune ... ADA deficiency is due to a lack of the enzyme adenosine deaminase. This deficiency results in an accumulation of deoxyadenosine ...
*  Adenosine
In the US, Adenosine is marketed as Adenocard. In India Adenosine is sold as Adenoscan (Cipla) All adenosine receptor subtypes ... and adenosine diphosphate (ADP)-as well as in signal transduction as cyclic adenosine monophosphate (cAMP). Adenosine itself is ... When adenosine enters the circulation, it is broken down by adenosine deaminase, which is present in red cells and the vessel ... Adenosine is believed to be an anti-inflammatory agent at the A2A receptor. Topical treatment of adenosine to foot wounds in ...
*  Adenosine diphosphate
... (ADP), also known as adenosine pyrophosphate (APP), is an important organic compound in metabolism and is ... ADP in the blood is converted to adenosine by the action of ecto-ADPases, inhibiting further platelet activation via adenosine ... ADP can be interconverted to adenosine triphosphate (ATP) and adenosine monophosphate (AMP). ATP contains one more phosphate ... The diphosphate group of ADP is attachted to the 5' carbon of the sugar backbone, while the adenosine attaches to the 1' carbon ...
*  Adenosine kinase
The role of adenosine kinase in regulating adenosine concentration. Biochem J 1985, 226: 343-344. Boison D: Adenosine as a ... Gupta RS: Adenosine-AMP exchange activity is an integral part of the mammalian adenosine kinase. Biochem Mol Biol Int 1996, 39 ... Adenosine kinase (AdK; EC 2.7.1.20) is an enzyme that catalyzes the transfer of gamma-phosphate from Adenosine triphosphate ( ... Arch JR, Newsholme EA: Activities and some properties of 5'-nucleotidase, adenosine kinase and adenosine deaminase in tissues ...
*  Adenosine nucleosidase
In enzymology, an adenosine nucleosidase (EC 3.2.2.7) is an enzyme that catalyzes the chemical reaction adenosine + H2O ⇌ {\ ... The systematic name of this enzyme class is adenosine ribohydrolase. Other names in common use include adenosinase, N- ... MAZELIS M, CREVELING RK (1963). "AN ADENOSINE HYDROLASE FROM BRUSSELS SPROUTS". J. Biol. Chem. 238: 3358-61. PMID 14085386. ... displaystyle \rightleftharpoons } D-ribose + adenine Thus, the two substrates of this enzyme are adenosine and H2O, whereas its ...
*  Adenosine monophosphate
... (AMP), also known as 5'-adenylic acid, is a nucleotide. AMP consists of a phosphate group, the sugar ... In a catabolic pathway, adenosine monophosphate can be converted to uric acid, which is excreted from the body. AMP can also ... including adenosine monophosphate, are formed. AMP can be regenerated to ATP as follows: AMP + ATP → 2 ADP (adenylate kinase in ... ribose, and the nucleobase adenine; it is an ester of phosphoric acid and the nucleoside adenosine. As a substituent it takes ...
*  Adenosine-tetraphosphatase
In enzymology, an adenosine-tetraphosphatase (EC 3.6.1.14) is an enzyme that catalyzes the chemical reaction adenosine 5'- ... The systematic name of this enzyme class is adenosine-tetraphosphate phosphohydrolase. This enzyme participates in purine ... the two substrates of this enzyme are adenosine 5'-tetraphosphate and H2O, whereas its two products are ATP and phosphate. This ...
*  Adenosine triphosphate
Adenosine diphosphate (ADP) Adenosine monophosphate (AMP) Adenosine-tetraphosphatase Adenosine methylene triphosphate ATPases ... Gajewski, E.; Steckler, D.; Goldberg, R. (1986). "Thermodynamics of the hydrolysis of adenosine 5′-triphosphate to adenosine 5 ... Energy ATP and Exercise PubChem entry for Adenosine Triphosphate KEGG entry for Adenosine Triphosphate. ... Adenosine 5′-(γ-thiotriphosphate) is an extremely common ATP analog in which one of the gamma-phosphate oxygens is replaced by ...
*  Adenosine deaminase
... (also known as adenosine aminohydrolase, or ADA) is an enzyme (EC 3.5.4.4) involved in purine metabolism. ... Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can ... Coformycin was also described as a adenosine deaminase inhibitor but is alleged to be an antibiotic. Adenosine deaminase ... Blackburn MR (2003). "Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice". Trends in ...
*  Adenosine thiamine triphosphate
... (AThTP), or thiaminylated adenosine triphosphate, is a natural thiamine adenine nucleotide. It ... Tanaka T, Yamamoto D, Sato T, Tanaka S, Usui K, Manabe M, Aoki Y, Iwashima Y, Saito Y, Mino Y, Deguchi H (2011). "Adenosine ... Jordan F (2007). "Adenosine triphosphate and thiamine cross paths". Nat. Chem. Biol. 3 (4): 202-3. doi:10.1038/nchembio0407-202 ... The molecule is made up of thiamine and adenosine joined together with phosphate groups. It is similar in structure to NAD+. ...
*  Adenosine 5'-tetraphosphate
Guranowski, A.; Günther Sillero, M.A.; Sillero, A. (1994). "Adenosine 5'-tetraphosphate and adenosine 5'-pentaphosphate are ... Adenosine 5'-tetraphosphate is a nucleotide. It is produced from ATP and triphosphate (P3) through the action of acetyl-CoA ... Acetyl-CoA synthetase also produces adenosine 5'-pentaphosphate through the reaction of ADP and tetraphosphate (P4). Its ...
*  Adenosine A2 receptor
Two subtypes of adenosine A2 receptors are known. Both are G protein-coupled adenosine receptors: Adenosine A2A receptor ...
*  Adenosine-phosphate deaminase
In enzymology, an adenosine-phosphate deaminase (EC 3.5.4.17) is an enzyme that catalyzes the chemical reaction 5'-AMP + H2O ... The systematic name of this enzyme class is adenosine-phosphate aminohydrolase. Other names in common use include adenylate ... deaminase, adenine nucleotide deaminase, and adenosine (phosphate) deaminase. Su JC, Li CC, Ting CC (1966). "A new adenylate ...
*  Adenosine diphosphate ribose
... is an ester molecule formed into chains by the enzyme poly ADP ribose polymerase. It binds to and ... Adenosine diphosphate Ribose Fonfria E, Marshall IC, Benham CD, et al. (September 2004). "TRPM2 channel opening in response to ...
*  Adenosine A1 receptor
The adenosine A1 receptor is one member of the adenosine receptor group of G protein-coupled receptors with adenosine as ... The adenosine A1 receptor has been found to be ubiquitous throughout the entire body. Activation of the adenosine A1 receptor ... Adenosine A1 Receptor at the US National Library of Medicine Medical Subject Headings (MeSH) Human ADORA1 genome location and ... Adenosine antagonists are widely used in neonatal medicine; Because a reduction in A1 expression appears to prevent hypoxia- ...
*  Adenosine reuptake inhibitor
"Adenosine and adenosine uptake inhibitors potentiate the neuromuscular blocking action of rocuronium mediated by adenosine A(1 ... York MJ, Davies LP (1982). "The effect of diazepam on adenosine uptake and adenosine-stimulated adenylate cyclase in guinea-pig ... Chaudary N, Naydenova Z, Shuralyova I, Coe IR (2004). "The adenosine transporter, mENT1, is a target for adenosine receptor ... An adenosine reuptake inhibitor (AdoRI) is a type of drug which acts as a reuptake inhibitor for the purine nucleoside and ...
*  Adenosine receptor antagonist
Adenosine receptor agonist Adenosine reuptake inhibitor Müller, CE; Jacobson, KA (2011). "Xanthines as adenosine receptor ... An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors. Examples ... Rivera-Oliver, Marla; Díaz-Ríos, Manuel (April 2014). "Using caffeine and other adenosine receptor antagonists and agonists as ... Hauber, W.; Muenkle, M. (July 1996). "The adenosine receptor antagonist theophylline induces a monoamine-dependent increase of ...
*  Adenosine thiamine diphosphate
... (AThDP), or thiaminylated adenosine diphosphate (ADP) is a naturally occurring thiamine adenine ...
*  Adenosine A2B receptor
The adenosine A2B receptor, also known as ADORA2B, is a G-protein coupled adenosine receptor, and also denotes the human ... 2001). "Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes ... Strohmeier GR, Reppert SM, Lencer WI, Madara JL (1995). "The A2b adenosine receptor mediates cAMP responses to adenosine ... alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting ...
*  Adenosine receptor agonist
Examples include the neurotransmitter adenosine, its phosphates, adenosine monophosphate (AMP), adenosine diphosphate (ADP), ... and adenosine triphosphate (ATP), and the pharmaceutical drug regadenoson. Adenosine receptor antagonist Adenosine reuptake ... An adenosine receptor agonist is a drug which acts as an agonist of one or more of the adenosine receptors. ...