AP-3 complex subunit delta-1 is a protein that in humans is encoded by the AP3D1 gene. AP3D1 is a subunit of the AP3 adaptor- ... "Entrez Gene: AP3D1 adaptor-related protein complex 3, delta 1 subunit". Martinez-Arca S, Rudge R, Vacca M, Raposo G, Camonis J ... "Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting ... Simpson F, Peden AA, Christopoulou L, Robinson MS (May 1997). "Characterization of the adaptor-related protein complex, AP-3". ...

The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the ... AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a ... "Entrez Gene: AP3M1 adaptor-related protein complex 3, mu 1 subunit". Human AP3M1 genome location and AP3M1 gene details page in ... 2000). "Interactions of HIV-1 nef with the mu subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based ...

... and a small subunit σ (sigma ~20 kD), and named 1 through 5 corresponding to the 5 AP complexes. Components of COPI (cop one) a ... In AP-1 it is named γ (gamma), AP-2 has α (alpha), AP-3 has δ (delta), AP-4 has ε (epsilon) and AP-5 has ζ (zeta). The two ... Most of the adaptor proteins are heterotetramers. In the AP complexes, there are two large proteins (~100 kD) and two smaller ... Vesicular transport adaptor proteins are proteins involved in forming complexes that function in the trafficking of molecules ...

Hanzal-Bayer M, Renault L, Roversi P, Wittinghofer A, Hillig RC (May 2002). "The complex of Arl2-GTP and PDE delta: from ... "Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family". FEBS Letters. 467 (1): 91-6. doi:10.1016/ ... Nancy V, Callebaut I, El Marjou A, de Gunzburg J (Apr 2002). "The delta subunit of retinal rod cGMP phosphodiesterase regulates ... Hanzal-Bayer M, Renault L, Roversi P, Wittinghofer A, Hillig RC (May 2002). "The complex of Arl2-GTP and PDE delta: from ...

... the plasma membrane the TCR receptor chains α and β associate with six additional adaptor proteins to form an octameric complex ... The two main subunits of TCR (α- and β-chains) are twisted together. CD3 and zeta subunits are required to carry out the signal ... The intersection of these specific regions (V and J for the alpha or gamma chain; V, D, and J for the beta or delta chain) ... LAT associates with another scaffolding protein Slp-76 via the Grap2 adaptor protein, which provides additional binding sites. ...

2001). "The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an ... San José E, Sahuquillo AG, Bragado R, Alarcón B (1998). "Assembly of the TCR/CD3 complex: CD3 epsilon/delta and CD3 epsilon/ ... "The implications of subunit interactions for the structure of the T cell receptor-CD3 complex". Eur. J. Immunol. 20 (2): 299- ... v t e (Articles with short description, Short description matches Wikidata, Human genes, Proteins, All stub articles, Protein ...

The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. Two ... Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M (Jul 2002). "Delta/notch-like epidermal growth factor (EGF)-related ... "Entrez Gene: AP1G1 adaptor-related protein complex 1, gamma 1 subunit". Fölsch H, Ohno H, Bonifacino JS, Mellman I (Oct 1999 ... "Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three- ...

The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are ... The Notch pathway, through transcriptional activation of Delta ligand (see DLL3). MET mediates a complex program known as ... Furge KA, Zhang YW, Vande Woude GF (November 2000). "Met receptor tyrosine kinase: enhanced signaling through adapter proteins ... Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses ...

Bellovino D, Morimoto T, Tosetti F, Gaetani S (Jan 1996). "Retinol binding protein and transthyretin are secreted as a complex ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library ... van Leeuwen JE, Kearse KP (Apr 1996). "Calnexin associates exclusively with individual CD3 delta and T cell antigen receptor ( ... Trombetta ES, Simons JF, Helenius A (Nov 1996). "Endoplasmic reticulum glucosidase II is composed of a catalytic subunit, ...

... either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also ... 2001). "Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the ... Protein transport protein Sec61 subunit alpha isoform 1 is a protein that in humans is encoded by the SEC61A1 gene. The protein ... 2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi: ...

"The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP ... Hanzal-Bayer M, Renault L, Roversi P, Wittinghofer A, Hillig RC (2002). "The complex of Arl2-GTP and PDE delta: from structure ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library ... ADP-ribosylation factor-like protein 3 is a protein that in humans is encoded by the ARL3 gene. ADP-ribosylation factor-like 3 ...

"The SH2-containing adapter protein GRB10 interacts with BCR-ABL". Oncogene. 17 (8): 941-8. doi:10.1038/sj.onc.1202024. PMID ... "p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl". Exp. ... Rommel C, Camps M, Ji H (2007). "PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and ... Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the ...

... adaptor protein complex beta subunits MeSH D12.776.543.990.150.500.300 - adaptor protein complex delta subunits MeSH D12.776. ... adaptor protein complex gamma subunits MeSH D12.776.543.990.150.500.500 - adaptor protein complex mu subunits MeSH D12.776. ... adaptor protein complex subunits MeSH D12.776.543.990.150.500.100 - adaptor protein complex alpha subunits MeSH D12.776.543.990 ... adaptor protein complex 1 MeSH D12.776.543.990.150.200 - adaptor protein complex 2 MeSH D12.776.543.990.150.300 - adaptor ...

Translation initiation factor eIF-2B subunit beta is a protein that in humans is encoded by the EIF2B2 gene. Eukaryotic ... "Characterization of the mammalian initiation factor eIF2B complex as a GDP dissociation stimulator protein". J. Biol. Chem. 276 ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (1996). "A "double adaptor" method for improved shotgun library ... It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon ( ...

... and that the SH2 domain of p85 specifically recognized phosphotyrosines on growth factor receptors or adaptor proteins via the ... Specifically, they discovered that the catalytic subunit p110 dimerizes with the regulatory subunit p85, ... control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb". Curr. Biol. 13 (15): 1259-68. doi:10.1016 ... The first drug targeting the PI-3-kinase pathway as a treatment for cancer - Idelalisib (PI3K Delta inhibitor) - was approved ...

This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in ... WHSC2 encodes the NELF-A subunit of the NELF complex. WHSC2 has been shown to interact with RDBP. GRCh38: Ensembl release 89: ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library ... "Stimulation of RNA polymerase II elongation by hepatitis delta antigen". Science. 293 (5527): 124-7. doi:10.1126/science. ...

... -S associates with two adaptor proteins: DAP10 and DAP12. DAP10 recruits the p85 subunit of PI3K and a complex of Grb2 and ... "NKG2D costimulates human V gamma 9V delta 2 T cell antitumor cytotoxicity through protein kinase C theta-dependent modulation ... adaptor protein and transduces the signal after the ligand binding by recruiting the p85 subunit of PI3K and Grb2-Vav1 complex ... NKG2D forms a homodimer and associates with adaptor proteins in its transmembrane domain to a hexameric complex structure and ...

HAUS augmin-like complex subunit 6 HEMGN: encoding protein hemogen IFN1@: Interferon, type 1, cluster IKBKAP: inhibitor of ... delta-, dehydratase ALS4: amyotrophic lateral sclerosis 4 ANGPTL2: angiopoietin-related protein 2 ASS: argininosuccinate ... signaling threshold regulating transmembrane adapter 1 SLC25A25-AS1: encoding protein SLC25A25 antisense RNA 1 SNORD24: ... zinc finger protein 79 ZNF367: encoding protein Zinc finger protein 367 ZNF510: zinc finger protein 510 The following diseases ...

These changes facilitate the recruitment of specific adapter proteins such as the insulin receptor substrate proteins (IRS) in ... "Differential effects of tumor necrosis factor-alpha on protein kinase C isoforms alpha and delta mediate inhibition of insulin ... Downstream post-translational events of either isoform result in the formation of a proteolytically cleaved α and β subunit, ... Strictly speaking the relationship between IR and ligand shows complex allosteric properties. This was indicated with the use ...

Leitges M, Gimborn K, Elis W, Kalesnikoff J, Hughes MR, Krystal G, Huber M (June 2002). "Protein kinase C-delta is a negative ... Not only catalytic but also adaptor activities of this protein are involved in this process. Its movement from the cytosol to ... Poe JC, Fujimoto M, Jansen PJ, Miller AS, Tedder TF (June 2000). "CD22 forms a quaternary complex with SHIP, Grb2, and Shc. A ... Zhang S, Broxmeyer HE (January 1999). "p85 subunit of PI3 kinase does not bind to human Flt3 receptor, but associates with SHP2 ...

Articles with short description, Short description matches Wikidata, Protein complexes, Cytokines). ... the pyrin domain of the adaptor protein ASC has recently been shown to function as a prion-like domain, through a self- ... Caspase-1 then assembles into its active form consisting of two heterodimers with a p20 and p10 subunit each. Once active, it ... May 2017). "The NLRP3 inflammasome modulates sleep and NREM sleep delta power induced by spontaneous wakefulness, sleep ...

The coatomer subunit delta (delta-COP) is a cytosolic protein complex that binds to motifs and associates with vesicles ... Molecular determinants regulating selective binding of autophagy adapters and receptors to ATG8 proteins. Nat Commun 10, 2055 ( ... Role of Mammalian Vacuolar Protein-sorting Proteins in Endocytic Trafficking of a Non-ubiquitinated G Protein-coupled Receptor ... There is no evidence of post-translational modifications of the TMEM267 protein found in tissues. According to protein sequence ...

... encoding protein 5-azacytidine-induced protein 2 BRK1: SCAR/WAVE actin nucleating complex subunit BRPF1: bromodomain and PHD ... alpha 2/delta subunit 3 CCR5: chemokine (C-C motif) receptor 5 CGGBP1: CGG triplet repeat binding protein 1 CMTM7: CKLF like ... Tumor protein p63 TRAT1: T-cell receptor-associated transmembrane adapter 1 USH3A: Usher syndrome 3A ZBED2: encoding protein ... encoding protein Zinc finger protein 197 ZNF502: encoding protein Zinc finger protein 502 ZNF620: encoding protein Zinc finger ...

It binds to the interleukin 18 binding protein (IL18BP), forming a complex with the beta subunit of the IL-18 receptor (IL-1F4 ... two intracellular adaptor proteins are assembled by conserved cytosolic regions called Toll- and IL-1R-like (TIR) domains. They ... August 2001). "Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B ... complex attaches K63-linked polyubiquitin chains to some of IL-1signaling intermediates, for instance TGF-β-activated protein ...

Some of the proteins that associate with HATs in these complexes function by targeting the HAT complex to nucleosomes at ... E1A adenovirus protein, and S-HDAg (hepatitis delta virus small delta antigen). p300/CBP have also been observed to acetylate β ... They usually function within a multisubunit complex in which the other subunits are necessary for them to modify histone ... These complexes include SAGA (Spt/Ada/Gcn5L acetyltransferase), PCAF, ADA (transcriptional adaptor), TFIID (transcription ...

The calcium channel consists of a complex of alpha-1, alpha-2/delta and beta subunits in a 1:1:1 ratio. The S3-S4 linkers of ... Calcium channel, voltage-dependent, L type, alpha 1C subunit (also known as Cav1.2) is a protein that in humans is encoded by ... Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Apr 1996). "A "double adaptor" method for improved shotgun library ... Cav1.2 is a subunit of L-type voltage-dependent calcium channel. This gene encodes an alpha-1 subunit of a voltage-dependent ...

"Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein ... a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in ... "Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho". J. Cell Biol. 162 (1): 99-111. doi: ... The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. ...

14-3-3 protein zeta/delta (14-3-3ζ) is a protein that in humans is encoded by the YWHAZ gene on chromosome 8. The protein ... For instance, 14-3-3ζ controls cellular senescence by complexing with BIS to chaperone protein folding of STAT3 and activate ... "14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules". The ... "Human signaling protein 14-3-3zeta interacts with platelet glycoprotein Ib subunits Ibalpha and Ibbeta". Blood. 91 (4): 1295- ...