"Endoplasmic Reticulum Stress-induced mRNA Splicing Permits Synthesis of Transcription Factor Hac1p/Ern4p That Activates the ... Cox, Jeffey S.; Walter, Peter (1996). "A Novel Mechanism for Regulating Activity of a Transcription Factor That Controls the ... transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway". Genes to Cells. ... ISR activates the EIF2α protein, reducing most protein synthesis and increasing the production of some regulatory molecules. ...

"Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription ... a novel zinc finger transcription factor that interacts with Msx2 and enhances its affinity for DNA". Mech Dev. 65 (1-2): 3-17 ... "Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor ... Protein inhibitor of activated STAT2 has been shown to interact with: Androgen receptor, DNMT3A, PARK7, and UBE2I. GRCh38: ...

Some of these problems have been listed below: The c-fos gene produces a transcription factor that is activated in several ... c-myc gene, also responsible for producing transcription factors found in several cancers, has also been reported to lack the ... nuclear transcription factors, and cytokines. AREs are one of the most common determinants of RNA stability in mammalian cells ... and transcription inhibitors. These observations suggest that AREs play a critical role in the regulation of gene transcription ...

The activity of different CDKs activate cell signaling pathways and transcription factors that regulate key events in mitosis ... Inhibition of transcription by MSK1 was most sensitive when the template was in chromatin, since DNA templates not in chromatin ... Researchers choose proteins that are known to modify histones to test their effects on transcription, and found that the stress ... Protein kinase N1 is responsible for the phosphorylation of the TNF receptor-associated factor (TRAF1) on serine 139 under ...

"MYRF Is a Membrane-Associated Transcription Factor That Autoproteolytically Cleaves to Directly Activate Myelin Genes". PLOS ... a p53-like transcription factor) and therefore likely act as a transcription factor. MyRF is a transcription factor that ... Senoo H, Wang HY, Araki T, Williams JG, Fukuzawa M (2012). "An orthologue of the Myelin-gene Regulatory Transcription Factor ... Myelin regulatory factor (MyRF), also known as myelin gene regulatory factor (MRF), is a protein that in humans is encoded by ...

"Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF". EMBO J. 18 (7): 1891-9. ... Upstream binding transcription factor (UBTF), or upstream binding factor (UBF), is a protein that in humans is encoded by the ... polymerase I associated factor 53 binds to the nucleolar transcription factor UBF and functions in specific rDNA transcription ... "Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF". ...

Transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon), also known as TFAP2E, is a human gene. The ... protein encoded by this gene is a transcription factor. Activating protein 2 Tummala R, Romano RA, Fuchs E, Sinha S (December ... Transcription factors, All stub articles, Human chromosome 1 gene stubs). ... Genes on human chromosome 1, Human gene pages with Wikidata item, ...

"Entrez Gene: ELF4 E74-like factor 4 (ets domain transcription factor)". Liu Y, Hedvat CV, Mao S, Zhu XH, Yao J, Nguyen H, Koff ... an ETS transcription factor, up-regulates lysozyme transcription in epithelial cells through interaction with promyelocytic ... ETS-related transcription factor Elf-4 is a protein that in humans is encoded by the ELF4 gene. GRCh38: Ensembl release 89: ... Miyazaki Y, Sun X, Uchida H, Zhang J, Nimer S (October 1996). "MEF, a novel transcription factor with an Elf-1 like DNA binding ...

Transcription factor 'Signal inducer and activator of transcription 3' (STAT3) is continuously activated in cancer cells. It ... These adhesion molecules are essential factors in regulating the inflammatory process. It is linked to the inhibition of ... ISBN 978-1-78034-559-8. OCLC 801865009.{{cite book}}: CS1 maint: multiple names: authors list (link) Silva, Cristiane França da ... 190: 1-8. doi:10.1016/j.plantsci.2012.03.006. hdl:2318/107602. ISSN 0168-9452. PMID 22608514. Elsebai, Mahmoud Fahmi; ...

... family of transcription factors. It activates E-box dependent transcription along with TCF3 (E47). ATOH1 is required for the ... Leow CC, Polakis P, Gao WQ (November 2005). "A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma". Annals of ... 2007). "Basic helix-loop-helix transcription factor profiling of lung tumors shows aberrant expression of the proneural gene ... "Proneural and proneuroendocrine transcription factor expression in cutaneous mechanoreceptor (Merkel) cells and Merkel cell ...

SPA targeting to the binding site for the activating transcription factor TFIIIA has been demonstrated to inhibit transcription ... "Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors". ... Transcription factor TFIIIA is an example of a naturally-occurring protein with zinc-finger motifs. Zinc-finger motifs bind ... Artificial transcription factor Antisense therapy Gene therapy RNA interference Young WB, Link CJ (2000). "Chimeric retroviral ...

Is a Subgroup 6 Type R2R3MYB Transcription Factor That Activates Anthocyanin Production". Frontiers in Plant Science. 9: 1300. ... 1 blueberries are all similar in size, shape, weight, and color-the total product can be no more than ten percent off-color and ... ISBN 978-1-84593-826-0 Sumner, Judith (2004). American Household Botany: A History of Useful Plants, 1620-1900. Timber Press. p ... The leaves of highbush blueberries can be either deciduous or evergreen, ovate to lanceolate, and 1-8 cm (1⁄2-3+1⁄4 in) long ...

Peroxisome proliferator-activated receptor alpha (PPARα) is a nuclear receptor that functions as a transcription factor. It ... PPARα functions as a transcription factor in two cases; as mentioned before when there is an increased demand for energy from ... fatty acids are the main fuel that require the PPARα to be activated so it is able in turn to activate the genes essential for ... The carnitine-mediated entry process is a rate-limiting factor for fatty acid oxidation and is an important point of regulation ...

"Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor γ in Adipogenesis". ... Kim JH, Song J, Park KW (March 2015). "The multifaceted factor peroxisome proliferator-activated receptor γ (PPARγ) in ... is a type II nuclear receptor functioning as a transcription factor that in humans is encoded by the PPARG gene. PPARG is ... The genes activated by PPARG stimulate lipid uptake and adipogenesis by fat cells. PPARG knockout mice are devoid of adipose ...

"Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C". Molecular and ... Yang SH, Galanis A, Sharrocks AD (Jun 1999). "Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors ... Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in ... MEF2C is a transcription factor in the Mef2 family. The gene is located at 5q14.3 on the minus (Crick) strand and is 200,723 ...

"Transcription factors activate genes through the phase separation capacity of their activation domains". Cell. 175 (7): 1842- ... He discovered that a small set of human embryonic stem cell master transcription factors form a core regulatory circuitry that ... According to Young, most genes experience transcription initiation, but it is the control of transcription elongation that ... "Master transcription factors and mediator establish super-enhancers at key cell identity genes". Cell. 153 (2): 307-19. doi: ...

... subunit of human TFIIA reveals functions critical for activated transcription". Genes & Development. 8 (19): 2324-35. doi: ... Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one ... transcription factors (GTFs) that are required for all transcription events that use RNA polymerase II. Other GTFs include ... Transcription+Factor+TFIIA at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ...

"Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5- ... The encoded protein seems to have inhibitory effects on various types of activated transcription, but it requires the RPB5- ... The protein encoded by this gene binds to RNA polymerase II subunit 5 (RPB5) and negatively modulates transcription through its ... "Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI". Science. 302 (5648): 1208-12. ...

2002). "Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA". Nat. Genet. 31 (3): 289-94. doi: ... "Control of mitochondrial transcription specificity factors (TFB1M and TFB2M) by nuclear respiratory factors (NRF-1 and NRF-2) ... Dimethyladenosine transferase 2; transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M ... "Entrez Gene: TFB2M transcription factor B2, mitochondrial". Hillen, HS; Morozov, YI; Sarfallah, A; Temiakov, D; Cramer, P (16 ...

... (AP-2) is a family of closely related transcription factors which plays a critical role in regulating gene ... Transcription+Factor+AP-2 at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles with short ... Williams T, Tjian R (1991). "Analysis of the DNA-binding and activation properties of the human transcription factor AP-2". ... Hilger-Eversheim K, Moser M, Schorle H, Buettner R (2000). "Regulatory roles of AP-2 transcription factors in vertebrate ...

The transcription factor PU.1 is known to directly activate transcription of the antiapoptotic BCL2A1 gene or inhibit ... transcription of the p53 tumor suppressor to promote cell survival, and is proposed to also directly activate HK3 transcription ... Sui D, Wilson JE (October 2000). "Interaction of insulin-like growth factor binding protein-4, Miz-1, leptin, lipocalin-type ... 428 (1): 197-202. doi:10.1016/j.bbrc.2012.10.041. PMID 23068103. Wyatt E, Wu R, Rabeh W, Park HW, Ghanefar M, Ardehali H (3 ...

The IL-22/IL-22R1/IL-10R2 complex activates intracellular kinases (JAK1, Tyk2, and MAP kinases) and transcription factors, ... Dumoutier L, Van Roost E, Colau D, Renauld JC (August 2000). "Human interleukin-10-related T cell-derived inducible factor: ... Growth Factor Reviews. 21 (4): 237-51. doi:10.1016/j.cytogfr.2010.04.002. PMID 20655797. Weger W, Hofer A, Wolf P, El-Shabrawi ... Growth Factor Reviews. 24 (1): 51-7. doi:10.1016/j.cytogfr.2012.07.002. PMC 4003867. PMID 22906768. Moore KW, de Waal Malefyt R ...

... transcriptional repressor complex to convert the transcription factor Gli3 to an activator which activates the transcription of ... Wnt7a also causes Lmx1b, a LIM Homebox gene (and thus a transcription factor), to be expressed. Lmx1b is involved in ... There have been many studies aimed at elucidating specific genes and transcription factors that are found responsible for limb ... Further investigation into these changes showed an increased rate of substitution in binding sites for transcription factors ...

The human BOK promoter is activated by the overexpression of members of the E2F hand transcription factor family. Typically, ... these transcription factors are involved in the promotion of S-phase, so there might be a connection between Bok expression and ... The Bok gene is activated and produces protein in different tissues. In mice, elevated Bok levels were detected in the ovary, ... a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL". The Journal of ...

Nabel, Gary; Baltimore, David (1987-04-22). "An inducible transcription factor activates expression of human immunodeficiency ... "An inducible transcription factor activates expression of human immunodeficiency virus in T cells". Nature. 326 (6114): 711-713 ... a host transcription factor. He completed his Internal Medicine residency at Brigham and Women's Hospital. Nabel joined the ... Osborn, L.; Kunkel, S.; Nabel, G. J. (1989-04-01). "Tumor necrosis factor alpha and interleukin 1 stimulate the human ...

"Hlx homeobox transcription factor negatively regulates interferon-gamma production in monokine-activated natural killer cells ... Hlx belongs to the class of homeobox transcription factors, initially cloned from a B-lymphocyte cell line. Targeted knockout ... Transcription factors, All stub articles, Human chromosome 1 gene stubs). ... The same factor controls gut proliferation, and Hlx governs its expression. Although these mice develop anaemia, it is likely ...

... and found it capable of activating the transcription factor NF-κB in mammalian cells. They speculated that TLR4 was a "pattern ... "RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice". ... "Identity of tumour necrosis factor and the macrophage-secreted factor cachectin". Nature. 316 (6028): 552-554. Bibcode: ... This activated NF-kB within cells of the fat body, leading to antimicrobial peptide secretion. Aware of this work, Charles ...

... in which activated monomeric GR binds to other transcription factors such as NF-κB and AP-1 and prevents these from up- ... which activate the GR to work through (at least) two signal transduction pathways, SEGRAMs activate the GR in such a way that ... The activated GR can then regulate gene expression via one of two pathways: Transactivation The first (direct) pathway is ... Binding of glucocorticoids to the GR activates the receptor by causing a conformational change in the GR and thus a ...

Activating transcription factor 4 upregulates this gene under metabolic stress conditions in hepatocyte cell lines. A loss of ... Salgado MC, Metón I, Anemaet IG, Baanante IV (2014). "Activating transcription factor 4 mediates up-regulation of alanine ... 46 (1): 158-65. doi:10.1002/hep.21667. PMID 17596883. S2CID 12779974. Glinghammar B, Rafter I, Lindström AK, Hedberg JJ, ...

Therefore, transcription factors are crucial for adipogenesis. Transcription factors, peroxis proliferator-activated receptor γ ... a lipid-activated transcription factor". Cell. 79 (7): 1147-56. doi:10.1016/0092-8674(94)90006-x. PMID 8001151. S2CID 54387527 ... other transcription factors function in the progression of differentiation. Adipocyte determination and differentiation factor ... C/EBPs, transcription factors, are members of the basic-leucine zipper class. cAMP, an inducer of adipogenesis, can promote ...