It localizes at the Z-disk and has been shown to bind to α-dystrobrevin, α-actinin, and desmin to act as a mechanical linker in ... in vitro coimmunoprecipitation assays could not detect an interaction between human desmuslin and α-actinin. In 2001, Titeux ...
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein ...
July 2000). "Cardiac phospholipase D2 localizes to sarcolemmal membranes and is inhibited by alpha-actinin in an ADP- ... July 2000). "Cardiac phospholipase D2 localizes to sarcolemmal membranes and is inhibited by alpha-actinin in an ADP- ...
... α-actinin and vinculin. This association causes a conformational shift in the integrin's tertiary structure, allowing ligand ...
However, mutations in podocyte proteins, such as nephrin, alpha-actinin 4, and podocin, are associated with proteinuria and ...
"A discrete amino terminal domain of Kv1.5 and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2 ...
"Cardiac phospholipase D2 localizes to sarcolemmal membranes and is inhibited by alpha-actinin in an ADP-ribosylation factor- ...
... and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes". Biochemical and Biophysical Research ...
Identified interaction partners include: CaMKII-alpha, alpha-Actinin and NR2B (via CaMKII-alpha), Cav1.3 (L-type Ca2+) channels ... and alpha-actinin-2". J. Biol. Chem. 280 (42): 35329-36. doi:10.1074/jbc.M502191200. PMID 16120608. Gregory SG, Barlow KF, ... actinin". J. Neurosci. 21 (2): 423-33. doi:10.1523/JNEUROSCI.21-02-00423.2001. PMC 6763799. PMID 11160423. Izawa I, Nishizawa M ...
2004). "The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F- ...
... capable of linking integrins to the actin cytoskeleton either directly or indirectly by interacting with vinculin and α-actinin ...
... this redistribution leads to collapse of actin microfilaments in the hepatocyte cytoskeleton and dislocation of a-actinin and ...
"Involvements of the ABC protein ABCF2 and α-actinin-4 in regulation of cell volume and anion channels in human epithelial cells ...
Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin- ... b-actinin b-Cap73 Bifocal Bistramide A BPAG1 Brevin (Gelsolin) c-Abl Calpactin (Annexin) CHO1 Cortactin CamKinase II Calponin ... 34kDA 45kDa p53 p58gag p116rip a-actinin Abl ABLIM Actin-Interacting MAPKKK ABP120 ABP140 Abp1p ABP280 (Filamin) ABP50 (EF-1a) ...
2002). "Ca(2+)-dependent inhibition of Na+/H+ exchanger 3 (NHE3) requires an NHE3-E3KARP-alpha-actinin-4 complex for ... Sodium-hydrogen exchange regulatory cofactor 2 has been shown to interact with SGK, Actinin alpha 4, Parathyroid hormone ... requires an NHE3-E3KARP-alpha-actinin-4 complex for oligomerization and endocytosis". J. Biol. Chem. United States. 277 (26): ...
1996). "Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing ...
... beta-spectrin dimer initiation site using recombinant peptides and correlation of its phasing with the alpha-actinin dimer site ...
Zhang Z, Lin SY, Neel BG, Haimovich B (January 2006). "Phosphorylated alpha-actinin and protein-tyrosine phosphatase 1B ...
... has been shown to interact with: Actinin, alpha 1, ADRB1, GLUT1, ITGA5, ITGA6, KIF1B, LRP1, LRP2, LHCGR, MYO6, RGS19, ...
Within the cell, the intracellular domain of integrin binds to the cytoskeleton via adapter proteins such as talin, α-actinin, ...
... actinin-2, is required for myoblast fusion". J. Biol. Chem. 275 (18): 13933-9. doi:10.1074/jbc.275.18.13933. PMID 10788519. Shi ... actinin-2, is required for myoblast fusion". J. Biol. Chem. 275 (18): 13933-9. doi:10.1074/jbc.275.18.13933. PMID 10788519. Iba ...
... binds the Src homology domain of nebulette and nebulin and tethers it to alpha-actinin via its C-terminal domain ... The Q529X myopalladin mutant demonstrated incompetence in recruiting key binding partners such as desmin, alpha-actinin and ... binding to the EF hand domains of alpha-actinin. The N-terminal region of myopalladin binds to the nuclear protein CARP, known ...
Finally, there were no N-terminal signal peptides, no cleavage sites for mitochondria, no actinin-type actin-binding motifs, ...
Zyxin has a variety of bind partners such as CRP, α-actinin, proto-oncogene Vav, p130, and members of Ena/VASP family of ...
During myotube differentiation, myopodin interacts with stress fibers prior to co-localizing with alpha actinin-2 at Z-discs in ... Myopodin interacts with: 14-3-3 beta, Actin, alpha, cardiac muscle 1, Actinin, alpha 2, Calcineurin, CaMKII, Importin 13, and ... by forming a Z-disc signaling complex with alpha actinin-2, calcineurin, CaMKII, muscle-specific A-kinase anchoring protein, ...
Alpha-actinin-3 is found only in skeletal muscle in humans, and has been identified in several genetic studies as having a ... enkephalin and alpha-actinin-3. The risks of gene doping would be similar to those of gene therapy: immune reaction to the ...
The motor structures are microfilaments of actin and actin-binding proteins, including α-actinin, fimbrin, and filamin are ...
"Actin-binding protein alpha-actinin-1 interacts with the metabotropic glutamate receptor type 5b and modulates the cell surface ...
Cardiac alpha actin is a filamentous protein extending from a complex mesh with cardiac alpha-actinin (ACTN2) at Z-lines ...
... was shown to localize together with α-actinin at the leading edge of membrane filopodia in glioblastoma cells, suggesting ...