... binding protein Calcium-binding protein 1 S100 calcium-binding protein A1 TATA-binding protein Actin-binding protein Most actin ... binding protein Nuclear cap-binding protein complex CREB-binding protein Calcium- ... binding protein Syntaxin binding protein 2 Oxysterol-binding protein E3 binding protein Iron-responsive element-binding protein ... Penicillin binding proteins Retinol binding protein Retinol binding protein 4 EP300 Binding immunoglobulin protein Odorant ...
... "actin nucleus" composed of 3 actin monomers from which an actin filament can be further elongated. The cobl-actin-nucleus is ... and is present in at least 6 classes of proteins WIP/Verprolin, Cibulot, Svv2/CAP, β-Thymosines, WAVE/Scar. WH2 proteins occur ... Protein cordon-bleu is a protein that in humans is encoded by the COBL gene. The Cordon-bleu protein was first described in ... This Cobl-actin tetramer is forming a nucleus to facilitate further G-actin addition. Cobl-mediated actin nucleation is very ...
... which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma ... Supervillin is a protein that in humans is encoded by the SVIL gene. This gene encodes a bipartite protein with distinct amino ... Its function may include recruitment of actin and other cytoskeletal proteins into specialized structures at the plasma ... contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins ...
The plus ends of the actin filaments are located at the tip of the microvillus and are capped, possibly by capZ proteins, while ... 20 to 30 tightly bundled actin filaments are cross-linked by bundling proteins fimbrin (or plastin-1), villin and espin to form ... The nucleation of actin fibers occurs as a response to external stimuli, allowing a cell to alter its shape to suit a ... Actin filaments, present in the cytosol, are most abundant near the cell surface. These filaments are thought to determine the ...
... and will dissociate F-Actin-capped pGSN. Actin is the most abundant cellular protein, and its release into extracellular fluid ... Plasma Gelsolin is a sticky protein known to bind to a number of peptides and proteins: Actin (see: Relationships with actin), ... 1 actin-pGSN complex, restoring its ability to sever F-actin. F-actin, severed and capped by pGSN, is removed by sinusoidal ... pGSN along with Vitamin D-binding protein (DBP) bind and clear monomeric actin. DBP binds with greater affinity to G-actin, ...
... actin-modulating protein that binds to the barbed ends of actin filaments, preventing monomer exchange (end-blocking or capping ... S2 and S3 bind to the actin before the binding of S1 severs actin-actin bonds and caps the barbed end. Gelsolin can be ... Actin can be cross-linked into a gel by actin cross-linking proteins. Gelsolin can turn this gel into a sol, hence the name ... Gelsolin is an actin-binding protein that is a key regulator of actin filament assembly and disassembly. Gelsolin is one of the ...
"Abnormal actin binding of aberrant β-tropomyosins is a molecular cause of muscle weakness in TPM2-related nemaline and cap ... "Protein sequence of human TPM2 (Uniprot ID: P07951)". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Retrieved 1 July ... "Protein sequence of human TPM2 (Uniprot ID: P07951-2)". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Retrieved 1 ... "Protein sequence of human TPM2 (Uniprot ID: P07951-3)". Cardiac Organellar Protein Atlas Knowledgebase (COPaKB). Retrieved 1 ...
Kioka N, Ueda K, Amachi T (Feb 2002). "Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal ... ArgBP2 is highly abundant in cardiac muscle cells at sarcomeric Z-disc structures, and is expressed in other cells at actin ... ArgBP2 protein, also referred to as Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the ... Nakayama M, Kikuno R, Ohara O (Nov 2002). "Protein-protein interactions between large proteins: two-hybrid screening using a ...
"Entrez Gene: PPP1R9A protein phosphatase 1, regulatory (inhibitor) subunit 9A". Maruyama K, Sugano S (1994). "Oligo-capping: a ... 2002). "Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology ... Stephens DJ, Banting G (1999). "Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding ... 1997). "Neurabin: A Novel Neural Tissue-specific Actin Filament-binding Protein Involved in Neurite Formation". J. Cell Biol. ...
Hubberstey A, Yu G, Loewith R, Lakusta C, Young D (June 1996). "Mammalian CAP interacts with CAP, CAP2, and actin". Journal of ... The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins ... "The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family". ... This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune ...
Kioka N (Jan 2003). "[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP ... a novel vinculin-binding protein with multiple SH3 domains enhances actin cytoskeletal organization". J Cell Biol. 144 (1): 59- ... 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode: ... Vinexin is a protein that in humans is encoded by the SORBS3 gene. SORBS3 has been shown to interact with DLG5 and MAPK1. ...
... a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head". Exp. Cell Res. 275 ... Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... Fascin-3 also known as testis fascin is a protein that in humans is encoded by the FSCN3 gene. Fascin GRCh38: Ensembl release ... close physical linkage of fascin and cytoplasmic actin genes". Genomics. 65 (2): 146-56. doi:10.1006/geno.2000.6156. PMID ...
Actin is one of the main cytoskeletal proteins in eukaryotic cells. The polymerization of actin filaments is responsible for ... Arp2/3 is able to cap the trailing ("minus") end of the actin filament, allowing for faster polymerization at the "plus" end. ... Ezrin attaches the actin-propelled bacterium to the plasma membrane by crosslinking the actin comet tail to the membrane, and ... Nucleation factors such as WASP (Wiskott-Aldrich syndrome protein) help to form the seven-protein Arp2/3 nucleation complex, ...
Tropomodulin is a protein that will cap the ends of the actin filaments causing the overall stability of the structure. Nebulin ... Actin Based Motor Protein- Myosin There are several different proteins that interact with actin in the body. However, one of ... Microfilaments are part of the cytoskeleton that are composed of protein called actin. Two strands of actin intertwined ... Cytochalasin is a toxin that will bind to the actin polymer, so it can no longer bind to the incoming actin monomers. Actin ...
CAP thus is a specialised protein in recycling of actin monomers, by first rapidly dissociating ADP-actin monomers from the ... Proteins that bind F-actin often regulate F-actin assembly and its interaction with other proteins, while proteins that ... In molecular biology, the cyclase-associated protein family (CAP) is a family of highly conserved actin-binding proteins ... Actin exists both as globular (G) (monomeric) actin subunits and assembled into filamentous (F) actin. In cells, actin cycles ...
... also mediates the recruitment of F-actin-capping protein dimer to the complex as well as the recruitment of the core ... The protein has a low immune cell, human brain regional, and a low tissue specificity. Some diseases that the protein are ... WASHC2C is involved in several other processes, negative regulation of barned-end actin filament capping, fluid base ... 2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. ...
Actin-like proteins are actin in eukaryotes and MreB, FtsA in prokaryotes. An example of a WACA-proteins, which are mostly ... Actin cables are bundles of actin filaments and are involved in the transport of vesicles towards the cap (which contains a ... Tubulin-like, actin-like, Walker A cytoskeletal ATPases (WACA-proteins), and intermediate filaments. Tubulin-like proteins are ... In general, the major component or protein of microfilaments are actin. The G-actin monomer combines to form a polymer which ...
... s are primarily composed of actin and myosin. Actin is a ~43kDa globular protein, and can polymerize to form long ... There are also a small subset of focal adhesion-associated integrins that terminate in the perinuclear actin cap (at the top of ... an actin filament crosslinking protein which contains antiparallel actin-binding domains. These bundles are then cross-linked ... catenin is an actin-binding and-bundling protein mediating the attachment of F-actin to the membrane adhesion complex". ...
LIM domain and actin-binding protein 1 is a protein that in humans is encoded by the LIMA1 gene. EPLIN is a cytoskeleton- ... "Entrez Gene: LIMA1 LIM domain and actin binding 1". Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the ... 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs ... associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles (Maul et al., 2003).[ ...
Actin-like protein 6A is a protein that in humans is encoded by the ACTL6A gene. This gene encodes a family member of actin- ... Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have ... "Alternative splicing products of the gene for a human nuclear actin-related protein, hArpNbeta/Baf53, that encode a protein ...
Arp2/3 complexes that give rise to actin branching and capping proteins. Due to the branching process and the density of the ... Spectrin proteins and actin microfilaments are attached to transmembrane proteins by attachment proteins between them and the ... the cortex is an actin-rich network consisting of F-actin filaments, myosin motors, and actin-binding proteins. The actomyosin ... The cell cortex is attached to the inner cytosolic face of the plasma membrane in cells where the spectrin proteins and actin ...
"Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells". Scientific Reports. 8 (1): ... "Ultraefficient Cap-Exchange Protocol To Compact Biofunctional Quantum Dots for Sensitive Ratiometric Biosensing and Cell ... Affimer proteins display two peptide loops that can all be randomized to bind to desired target proteins, in a similar manner ... Affimers that inhibit protein-protein interactions can be produced with the potential to express these inhibitors in mammalian ...
The product of this gene is a member of the BAR domain protein family. The encoded protein is composed solely of a BAR domain ... Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... 2001). "Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p ... BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes. GRCh38 ...
CapZ/Capping Protein a-Catenin Cofilin CR16 Caldesmon CCT Comitin Calicin Centuarin Coronin DBP40 Drebrin Dematin (Band 4.9) ... Actin-binding proteins (also known as ABPs) are proteins that bind to actin. This may mean ability to bind actin monomers, or ... ActA Actibind Actin Actinfilin Actinogelin Actin-regulating kinases Actin-Related Proteins Actobindin Actolinkin Actopaxin ... Many actin-binding proteins, including α-actinin, β-spectrin, dystrophin, utrophin and fimbrin, do this through the actin- ...
... encoding protein Apoptosis-related protein 3 BCYRN1: BC200 lncRNA C2orf16: unknown protein C2orf16 CAPG: capping acting protein ... encoding protein Villin 1 XIRP2: Xin actin-binding repeat-containing protein 2 ZEB2-AS1: encoding protein ZEB2-AS1 ZNF142: zinc ... encoding protein Erythrocyte membrane protein band 4.1 like 5 ERICH2: encoding protein Glutamate rich protein 2 FASTKD1: FAST ... MAL-like protein MBD5: encoding protein Methyl-cpg binding domain protein 5 MFSD2B: encoding protein Major facilitator ...
LRET was also used to study the interaction of the proteins dystrophin and actin in muscle cells. Dystrophin is present in the ... to measure distances in DNA complexes bent by the CAP protein. Lanthanide probes have been used to detect conformational ... Lanthanides can be used because their small size (ionic radius) gives them the ability to replace metal ions inside protein ... Pulsed lasers for the 300 to 500 nm range have now replaced spark caps in fluorescence spectroscopy. There are four general ...
"A new MIF4G domain-containing protein, CTIF, directs nuclear cap-binding protein CBP80/20-dependent translation". Genes & ... Supervillin, or SVIL, which is a peripheral membrane protein that forms a high-affinity link between the actin cytoskeleton and ... MIF4GD, or MIF4G domain-containing protein, is a protein which in humans is encoded by the MIF4GD gene. It is also known as ... It is not likely that the MIF4GD protein will be lipid-linked or glycosylated. The MIF4GD protein that contains an MIF4G domain ...
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... Flotillin-1 is a protein that in humans is encoded by the FLOT1 gene. Caveolae are small domains on the inner cell membrane ... 2004). "Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites". J ... Kimura A, Baumann CA, Chiang SH, Saltiel AR (July 2001). "The sorbin homology domain: a motif for the targeting of proteins to ...
... is a type III intermediate filament (IF) protein that is expressed in mesenchymal cells. IF proteins are found in all ... Scientists found that vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when ... capped on each end by non-helical amino (head) and carboxyl (tail) domains. Two monomers are likely co-translationally ... Herrmann H, Wiche G (January 1987). "Plectin and IFAP-300K are homologous proteins binding to microtubule-associated proteins 1 ...
Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness ... Coronin-6 belongs to the coronin family which is an actin binding protein. Human CORO6 gene is located on chromosome 17 on the ... de Hostos EL, Eugenio L (September 1999). "The coronin family of actin-associated proteins". Trends Cell Biol. 9 (9): 345-50. ... Coronin-6 also known as coronin-like protein E (Clipin-E) is a protein that in humans is encoded by the CORO6 gene. ...
White SJ, McLean WH (2005). "Kindler surprise: mutations in a novel actin-associated protein cause Kindler syndrome". J. ... Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... a Human Homolog of the Caenorhabditis elegans Actin-Extracellular-Matrix Linker Protein UNC-112, Causes Kindler Syndrome". Am J ... 2004). "Identification of mutations in a new gene encoding a FERM family protein with a pleckstrin homology domain in Kindler ...
Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin- ... Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with ... 2004). "Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin ... Harigaya Y, Shoji M, Shirao T, Hirai S (1996). "Disappearance of actin-binding protein, drebrin, from hippocampal synapses in ...