... however this is much weaker than the inhibition seen with N-acetylgalactosamine (range 92-100%).[1] ... "Inhibition of elastase enzyme release from human polymorphonuclear leukocytes by N-acetyl-galactosamine and N-acetyl- ...
N-Acetylgalactosamine. References[edit]. This article needs additional citations for verification. Please help improve this ...
Glaser L (November 1959). "The biosynthesis of N-acetylgalactosamine". The Journal of Biological Chemistry. 234 (11): 2801-5. ...
White square = N-acetyl-galactosamine; black circle = galactose; Black square = N-acetyl-glucosamine. Note: There is a mistake ... A Core 2 structure is generated by the addition of N-acetyl-glucosamine to the N-acetyl-galactosamine of the Core 1 structure. ... Core 3 structures are generated by the addition of a single N-acetyl-glucosamine to the original N-acetyl-galactosamine. Core 4 ... The first monosaccharide attached in the synthesis of O-linked glycans is N-acetyl-galactosamine. After this, several different ...
N-acetylgalactosamine-6-sulfatase is an enzyme that, in humans, is encoded by the GALNS gene. This gene encodes N- ... N-acetylgalactosamine-6-sulfate sulfatase exonic point mutations in classical Morquio and mild cases". J. Clin. Invest. 90 (3 ... Masue M, Sukegawa K, Orii T, Hashimoto T (1992). "N-acetylgalactosamine-6-sulfate sulfatase in human placenta: purification and ... Jan 1992). "Morquio disease: isolation, characterization and expression of full-length cDNA for human N-acetylgalactosamine-6- ...
The repeating unit (except for keratan) consists of an amino sugar (N-acetylglucosamine or N-acetylgalactosamine) along with a ... GalNAc(4S,6S) = β-D-N-acetylgalactosamine-4-O, 6-O-sulfate ... GalNAc = β-D-N-acetylgalactosamine. *GalNAc(4S) = β-D-N- ... GalNAc(6S) = β-D-N-acetylgalactosamine-6-O-sulfate. * ...
This gene product mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of this gene ...
Baig, S.; Wilcock, G.; Love, S. (2005). "Loss of perineuronal net N-acetylgalactosamine in Alzheimer's disease". Acta ...
"UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [Homo sapien - Protein - NCBI]". www.ncbi.nlm.nih.gov. Retrieved 2016 ...
UDP-N-acetylgalactosamine: (N-acetylneuraminyl)-galactosylglucosyl ceramide N-acetylgalactosaminyltransferase in rat brain". ... Hashimoto Y, Sekine M, Iwasaki K, Suzuki A (December 1993). "Purification and characterization of UDP-N-acetylgalactosamine GM3 ... UDP acetylgalactosamine-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide acetylgalactosaminyltransferase, UDP-N-acetyl-D- ... UDP-N-acetylgalactosamine GM3 N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine- ...
Aldurazyme by BioMarin Pharmaceutical and Genzyme N-acetylgalactosamine-4-sulfatase (rhASB; galsulfase): Naglazyme by BioMarin ...
"Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". The Journal of ... "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using ...
Ohtake S, Ito Y, Fukuta M, Habuchi O (Nov 2001). "Human N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase cDNA is related to ... It belongs to the N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase enzyme class. GRCh38: Ensembl release 89: ... "Difference between N-acetylgalactosamine 4-sulfate 6-O-sulfotransferases from human serum and squid cartilage in specificity ... "A unique nonreducing terminal modification of chondroitin sulfate by N-acetylgalactosamine 4-sulfate 6-o-sulfotransferase". J. ...
GSTs catalyze sulfation at the 6-hydroxyl group of galactose, N-acetylgalactosamine, or N-acetylglucosamine. Like heparan ... There are two major families of carbohydrate sulfotransferases: heparan sulfotransferases and galactose/N-acetylgalactosamine/N ... which transfer sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. ... "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". J. Biol. Chem. 276 ( ...
... (EC 2.8.2.35, dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase, dermatan-4- ... "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase". The Journal of ... "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using ... sulfotransferase-1, dermatan-4-sulfotransferase 1, D4ST-1, dermatan N-acetylgalactosamine 4-O-sulfotransferase, CHST14 protein ...
... (N-acetylgalactosamine-4-sulfatase, chondroitinsulfatase, chondroitinase, acetylgalactosamine 4-sulfatase, N- ... Galsulfase (N-acetylgalactosamine-4-sulfatase, recombinant human) was granted orphan drug designation by both the European ... N-acetylgalactosamine-4-sulfatase): potential role as a biomarker in prostate cancer". Prostate Cancer and Prostatic Diseases. ... This disease is caused by the lack of an enzyme called N-acetylgalactosamine 4-sulfatase, which is needed to break down ...
The sugars are usually a combination of N-acetylgalactosamine, D-glucose or D-galactose. A glycosphingolipid that has only one ...
Taniguchi N, Makita A (1984). "Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N- ... Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase". ... Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N- ... N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding ...
Taniguchi N, Makita A (1984). "Purification and characterization of UDP-N-acetylgalactosamine: globotriaosylceramide beta-3-N- ... Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase". ...
Warren, G.; Tooze, J.; Tooze, S. A. (1988-05-01). "Site of addition of N-acetyl-galactosamine to the E1 glycoprotein of mouse ...
The first sugar is always N-acetyl-galactosamine (GalNAc), followed by other galactoses and sialic acid. In HSP and IgAN, these ...
The galactose component originates from UDP-galactose and the GalNAc component originates from UDP-N-acetylgalactosamine. These ... is an exopolysaccharide composed of galactose and N-acetylgalactosamine (GalNAc). It is commonly found in the biofilm and cell ...
UDP-N-acetylgalactosamine:polypeptide, N-acetylgalactosaminyltransferase, and UDP-N-acetylgalactosamine:protein N- ... UDP-N-acetylgalactosamine-glycoprotein, N-acetylgalactosaminyltransferase, UDP-N-acetylgalactosamine-protein N- ... polypeptide-N-acetylgalactosamine transferase, UDP-acetylgalactosamine-glycoprotein, acetylgalactosaminyltransferase, UDP- ... Takeuchi M, Yoshikawa M, Sasaki R, Chiba H (1985). "Purification and characterization of UDP-N-acetylgalactosamine-kappa-casein ...
The enzyme coded for by IA adds an N-acetylgalactosamine to a membrane-bound H antigen. The IB enzyme adds a galactose. The i ...
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase Amado M, Almeida R, Schwientek T, Clausen H (December 1999). " ... Core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1, also known as C1GALT1, is an enzyme which ...
"Site-Specific Incorporation of the Mucin-Type N-Acetylgalactosamine-α-O-threonine into Protein in Escherichia coli". Journal of ... "Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli". ...
... characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine ...
This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O- ... "Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N- ...