2-oxobutyrate is ultimately decomposed by acetate-CoA ligase and produces ATP, thus contributing to ATP metabolism. MGL also ...
... lactate ligase EC 6.2.1.1: acetate-CoA ligase EC 6.2.1.2: butyrate-CoA ligase EC 6.2.1.3: long-chain-fatty-acid-CoA ligase EC ... acid-CoA ligase (GDP-forming) EC 6.2.1.11: biotin-CoA ligase EC 6.2.1.12: 4-coumarate-CoA ligase EC 6.2.1.13: acetate-CoA ... glutarate-CoA ligase EC 6.2.1.7: cholate-CoA ligase EC 6.2.1.8: oxalate-CoA ligase EC 6.2.1.9: malate-CoA ligase EC 6.2.1.10: ... arachidonate-CoA ligase EC 6.2.1.16: acetoacetate-CoA ligase EC 6.2.1.17: propionate-CoA ligase EC 6.2.1.18: citrate-CoA ligase ...
Types include: Acetate-CoA ligase (ADP-forming) Butyrate-CoA ligase Citrate-CoA ligase Malate-CoA ligase Succinate-CoA ligase ( ... A Thiokinase is a ligase that synthesizes CoA Thioesters. They are classified under EC number 6.2, but often have primary names ... ADP-forming) Succinate-CoA ligase (GDP-forming) Biology portal v t e. ...
... may refer to: Acetate-CoA ligase (ADP-forming), an enzyme Acetyl-CoA synthetase (or Acetyl-CoA ligase), an ...
... (ACS) or Acetate-CoA ligase is an enzyme (EC 6.2.1.1) involved in metabolism of acetate. It is in the ... Acetate + CoA <=> AMP + Pyrophosphate + Acetyl-CoA Once acetyl-CoA is formed it can be used in the TCA cycle in aerobic ... Co-A then rotates in the active site into the position where acetate can covalently bind to CoA. The covalent bond is formed ... The two molecules joined together that make up Acetyl CoA are acetate and coenzyme A (CoA). The complete reaction with all the ...
Acetyl-CoA synthase (ACS), not to be confused with Acetyl-CoA synthetase or Acetate-CoA ligase (ADP forming), is a nickel- ... the Wood-Ljungdahl pathway allows for the anaerobic oxidation of acetate where ATP is used to convert acetate into acetyl-CoA, ... For example, acetate-forming bacteria use acetyl-CoA for their autotrophic growth processes, and methanogenic archae such as ... In addition to acetyl-CoA production, the reverse can occur with ACS producing acetate, CO and returning the methyl piece back ...
... an acetate-CoA ligase (ADP-forming) (EC 6.2.1.13) is an enzyme that catalyzes the chemical reaction ATP + acetate + CoA ⇌ {\ ... The systematic name of this enzyme class is acetate:CoA ligase (ADP-forming). Other names in common use include acetyl-CoA ... acetate, and CoA, whereas its 3 products are ADP, phosphate, and acetyl-CoA. This enzyme belongs to the family of ligases, ... Pyruvate synthase and a new acetate thiokinase". J. Biol. Chem. 252 (2): 726-31. PMID 13076. Biology portal v t e. ...
... acetate:CoA ligase (AMP-forming). This enzyme catalyses the following chemical reaction [(1R)-2,2,3-trimethyl-5-oxocyclopent-3- ... 2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase (EC 6.2.1.38, 2-oxo-Delta3-4,5,5-trimethylcyclopentenylacetyl-CoA ... enyl]acetate + ATP + CoA ⇌ {\displaystyle \rightleftharpoons } AMP + diphosphate + [(1R)-2,2,3-trimethyl-5-oxocyclopent-3-enyl] ... 2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA+synthase at the US National Library of Medicine Medical Subject Headings (MeSH ...
... succinyl-CoA:acetate CoA-transferase. This specialized enzyme links the TCA cycle with acetate metabolism in these organisms.[ ... Most organisms utilize EC 6.2.1.5, succinate-CoA ligase (ADP-forming) (despite its name, the enzyme operates in the pathway in ... Succinyl-CoA + GDP + Pi Succinate + CoA-SH + GTP Succinyl-CoA synthetase substrate-level. phosphorylation or ADP→ATP instead of ... CH3C(=O)C(=O)O−pyruvate + HSCoA + NAD+ → CH3C(=O)SCoAacetyl-CoA + NADH + CO2. The product of this reaction, acetyl-CoA, is the ...
... coenzyme a ligases MeSH D08.811.464.267.500.200 - acetate-coa ligase MeSH D08.811.464.267.500.600 - succinate-coa ligases MeSH ... acyl-coa dehydrogenase, long-chain MeSH D08.811.682.660.150.200 - acyl-CoA oxidase MeSH D08.811.682.660.150.300 - butyryl-coa ... alanine-tRNA ligase MeSH D08.811.464.263.200.100 - arginine-tRNA ligase MeSH D08.811.464.263.200.150 - aspartate-tRNA ligase ... glycine-trna ligase MeSH D08.811.464.263.200.400 - histidine-trna ligase MeSH D08.811.464.263.200.450 - isoleucine-trna ligase ...
... which is in turn converted to feruloyl-CoA by the enzyme 4-hydroxycinnamoyl-CoA ligase (4CL). Next, feruloyl-CoA is reduced to ... forming coniferyl acetate. Finally, coniferyl acetate is converted to eugenol via the enzyme eugenol synthase 1 and the use of ... coniferaldehyde by cinnamoyl-CoA reductase (CCR). Coniferaldeyhyde is then further reduced to coniferyl alcohol by cinnamyl- ...
Once inside the cell long-chain-fatty-acid-CoA ligase catalyzes the reaction between a fatty acid molecule with ATP (which is ... acetate) units, which, combined with co-enzyme A, form molecules of acetyl CoA, which condense with oxaloacetate to form ... Acetyl-CoA is formed into malonyl-CoA by acetyl-CoA carboxylase, at which point malonyl-CoA is destined to feed into the fatty ... acetyl-CoA and 1 molecule of propionyl-CoA per molecule of fatty acid. Each beta oxidative cut of the acyl-CoA molecule yields ...
EC 6.2.1.12: 4-coumarate--CoA ligase. *EC 6.2.1.13: Acetate--CoA ligase (ADP-forming) ... EC 6.2.1.40: 4-hydroxybutyrate--CoA ligase. *EC 6.2.1.41: 3-((3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl) ... Category:Ligases (EC 6) (Ligase)Edit. Category:EC 6.1 (form carbon-oxygen bonds)Edit. 6-carboxytetrahydropterin synthase ... 6 Category:Ligases (EC 6) (Ligase) *6.1 Category:EC 6.1 (form carbon-oxygen bonds) ...
Oxalate-CoA ligase Formyl-CoA transferase Oxalate CoA-transferase Baetz AL, Allison MJ (July 1990). "Purification and ... a required enzyme for isoleucine and valine biosynthesis in Escherichia coli K-12 during growth on acetate as the sole carbon ... The systematic name of this enzyme class is oxalyl-CoA carboxy-lyase (formyl-CoA-forming). Other names in common use include ... This addition is followed by the decarboxylation of oxalyl-CoA, and then the oxidation and removal of formyl-CoA to regenerate ...
These may be metal ions, vitamin derivatives such as NADH and acetyl CoA, or non-vitamin derivatives such as ATP. In the case ... Okazaki fragments are covalently joined by DNA ligase to form a continuous strand. Then, to complete DNA replication, RNA ... Organisms that use ethanol and acetate as the major carbon source utilize the glyconeogenic pathway to synthesize glycine. The ... Cholesterol is synthesized from acetyl CoA. The pathway is shown below: More generally, this synthesis occurs in three stages, ...
It is also inhibited by succinyl-CoA and propionyl-CoA, which resembles Acetyl-coA and acts as a competitive inhibitor to ... Citrate synthase catalyzes the condensation reaction of the two-carbon acetate residue from acetyl coenzyme A and a molecule of ... These experiments have revealed that this single site alternates between two forms, which participate in ligase and hydrolase ... This induces the enzyme to change its conformation, and creates a binding site for the acetyl-CoA. Only when this citryl-CoA ...
CoA ligases and requires energy in the form of ATP. ... The benzoyl-CoA is then conjugated to glycine by GLYAT to form hippuric ... Sodium acetate has been used instead of pyridine. In the 20th century chloroacetone, benzene, and anhydrous aluminum chloride ... First benzoate is ligated to CoASH to form the high-energy benzoyl-CoA thioester. This reaction is catalyzed by the HXM-A and ... Acetate". Journal of Forensic Sciences. 37 (1): 301-322. doi:10.1520/JFS13235J. ISSN 0022-1198. The illicit synthesis of phenyl ...
It is the oxidation of the acetate portion of acetyl-CoA that produces CO2 and water, with the energy thus released captured in ... kynurenine hydroxylase and fatty acid Co-A ligase. Disruption of the outer membrane permits proteins in the intermembrane space ... Acetyl-CoA, on the other hand, derived from pyruvate oxidation, or from the beta-oxidation of fatty acids, is the only fuel to ... With each turn of the cycle one molecule of acetyl-CoA is consumed for every molecule of oxaloacetate present in the ...
... acetyl-CoA hydrolase EC 3.1.2.2: palmitoyl-CoA hydrolase EC 3.1.2.3: succinyl-CoA hydrolase EC 3.1.2.4: 3-hydroxyisobutyryl-CoA ... glutamate-ammonia ligase) hydrolase EC 3.1.4.16: 2',3'-cyclic-nucleotide 2'-phosphodiesterase EC 3.1.4.17: 3',5'-cyclic- ... methylumbelliferyl-acetate deacetylase EC 3.1.1.57: 2-pyrone-4,6-dicarboxylate lactonase EC 3.1.1.58: N- ... bile-acid-CoA hydrolase EC 3.1.2.27: choloyl-CoA hydrolase EC 3.1.2.28: 1,4-dihydroxy-2-naphthoyl-CoA hydrolase EC 3.1.2.29: ...
3-oxoadipate CoA-transferase EC 2.8.3.7: succinate-citramalate CoA-transferase EC 2.8.3.8: acetate CoA-transferase EC 2.8.3.9: ... protein ligase EC 2.7.7.64: UTP-monosaccharide-1-phosphate uridylyltransferase EC 2.7.7.65: diguanylate cyclase EC 2.7.7.66: ... succinyl-CoA:(R)-benzylsuccinate CoA-transferase EC 2.8.3.16: formyl-CoA transferase EC 2.8.3.17: cinnamoyl-CoA:phenyllactate ... oxalate CoA-transferase EC 2.8.3.3: malonate CoA-transferase EC 2.8.3.4: deleted EC 2.8.3.5: 3-oxoacid CoA-transferase EC 2.8. ...
The oxidation of acetaldehyde to acetate can be summarized as follows: Acetaldehyde + NAD+ + Coenzyme A ↔ Acetyl-CoA + NADH + H ...
cellular response to phorbol 13-acetate 12-myristate. • cellular response to ionomycin. • response to drug. • transcription ... acetyl-CoA carboxylase) kinase (EC 2.7.11.27). *-. Tropomyosin kinase (EC 2.7.11.28). *- ...
... acetate and choline. This is somewhat unusual among neurotransmitters as most, including serotonin, dopamine, and ... HMG-CoA reductase. *1.3 5α-Reductase. *1.4 Monoamine oxidase. *1.5 Dihydrofolate reductase ...
Ubiquitin ligases transfer ubiquitin to its pendant, proteins, and caspases, which engage in proteolysis in the apoptotic cycle ... The enzyme O-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releasing acetate.[12] ... G→propionyl-CoA→. succinyl-CoA. valine→. *α-Ketoisovaleric acid. *Isobutyryl-CoA. *Methacrylyl-CoA ...
Ubiquitin ligases transfer ubiquitin to its pendant, proteins, and caspases, which engage in proteolysis in the apoptotic cycle ... The enzyme O-acetylserine (thiol)-lyase, using sulfide sources, converts this ester into cysteine, releasing acetate.[12] ... G→propionyl-CoA→. succinyl-CoA. valine→. *α-Ketoisovaleric acid. *Isobutyryl-CoA. *Methacrylyl-CoA ...