In the PNS, injury to the plexus nerves presents as radiation-induced brachial plexopathy or radiation-induced lumbosacral ... However, double-stranded DNA breaks are much more difficult to repair, and can lead to dramatic chromosomal abnormalities and ... and can also cause radiation cystitis when the bladder is affected. Radiation-induced polyneuropathy Radiation treatments may ... Cardiovascular late side effects have been termed radiation-induced heart disease (RIHD) and radiation-induced cardiovascular ...

Sonography does not use ionizing radiation, and the power levels used for imaging are too low to cause adverse heating or ... The ultrasound does not interact directly with molecules to induce the chemical change, as its typical wavelength (in the ... According to RadiologyInfo, ultrasounds are useful in the detection of pelvic abnormalities and can involve techniques known as ... The UK's independent Advisory Group on Non-ionising Radiation (AGNIR) produced a report in 2010, which was published by the UK ...

NREs can induce a bend in the promoter region to block interactions, as seen when an NRE binds to Yin-Yang 1 (YY1), and flank ... UV and ionizing radiation, heat). Silencers, being encoded in the genome, are susceptible to such alterations which, in many ... of both NRSE and NRSF in mammals prevents not only neural dysfunctions but also physiological and phenotypical abnormalities in ... A silencer is a sequence-specific element that induces a negative effect on the transcription of its particular gene. There are ...

The majority of radiation-induced brain cancers are caused by ionizing radiation from medical sources such as CT scans. ... an indication of abnormality of a cell (which may be indicative of malignancy). Significance of the abnormality is highly ... Chemotherapy is often used in young children instead of radiation, as radiation may have negative effects on the developing ... In standard external beam radiation therapy, multiple treatments of standard-dose "fractions" of radiation are applied to the ...

In situations where the testes are normal but unstimulated, gonadotropin therapy can be expected to induce sperm production. A ... radiation, or other causes. Mast cells releasing inflammatory mediators appear to directly suppress sperm motility in a ... abnormalities on karyotyping versus about 45 ID/mL) have been correlated with successful microdissection testicular sperm ... The most common reason is a vasectomy done to induce contraceptive sterility. Other obstructions can be congenital (for example ...

"Radiation exposure and pregnancy". Journal of Vascular Surgery. Radiation Safety in Vascular Surgery. 53 (1 Suppl): 28S-34S. ... Reasons to induce can include pre-eclampsia, foetal distress, placental malfunction, intrauterine growth retardation and ... as well as congenital abnormalities. Fetal karyotype can be used for the screening of genetic diseases. This can be obtained ... X-rays and computerized tomography (CT) are not used, especially in the first trimester, due to the ionizing radiation, which ...

Induced genetic abnormality assays including microchromosome reverse mutation and E. coli mutagenicity assays were completed ... Beaven AW, Shea TC (September 2007). "The effect of palifermin on chemotherapyand radiation therapy-induced mucositis: a review ... McDonnell AM, Lenz KL (January 2007). "Palifermin: role in the prevention of chemotherapy- and radiation-induced mucositis". ... When patients with blood cancers (leukemia and lymphoma) receive high dose chemotherapy and radiation therapy to undergo bone ...

Hyperglycemia-induced formation of advanced glycation end products (AGEs) is related to diabetic neuropathy. Other causes ... Motor symptoms include loss of function ("negative") symptoms of weakness, tiredness, muscle atrophy, and gait abnormalities; ... radiation therapy, excessive alcohol consumption, immune system disease, celiac disease, non-celiac gluten sensitivity, or ... Xu W, Cox CS, Li Y (2011). "Induced pluripotent stem cells for peripheral nerve regeneration". Journal of Stem Cells. 6 (1): 39 ...

The two echocardiogram images are then compared to assess for any abnormalities in wall motion of the heart. This is used to ... The stress response is induced by exercise, intravenous pharmacological (drug) stimulation, or in some cases, a combination of ... The typical dose of radiation received during this procedure can range from 9.4 to 40.7 millisieverts. The American Heart ... Exercise-induced stressors are most commonly either exercise on a treadmill or pedalling a stationary exercise bicycle ...

Fission products emit beta radiation, while actinides primarily emit alpha radiation. Many of each also emit gamma radiation. ... Studies of chronically exposed workers though have thus far failed to detect any abnormalities of thyroid function, including ... Bartalena, L.; Brogioni, S; Grasso, L; Bogazzi, F; Burelli, A; Martino, E (1996). "Treatment of amiodarone-induced ... Thus, fission events normally result in beta and gamma radiation, even though this radiation is not produced directly by the ...

... which emit a great deal of infrared radiation through black-body radiation. The ocular lens, like all matter, has the capacity ... A slit lamp is used because it makes it easier for ophthalmologists to spot abnormalities. When the eye is dilated, the pupils ... this increase could therefore induce the cataract. This however has not been proven to be true and instead it is generally ... The infrared radiation is absorbed by the iris and lens of the eye. This causes cataracts after decades of exposure. This ...

Treatment may involve surgical removal and radiation therapy, depending on the level of bone penetration and stage in the ... Because of their crucial role in maintaining and regulating endothelial cell structure and blood flow, abnormalities in ... While both types are able to proliferate in response to glycerol or BaCl2-induced injury, type-1 pericytes give rise to ... cardiac and placental abnormalities". Development. 131 (8): 1847-57. doi:10.1242/dev.01080. PMID 15084468. Paik JH, Skoura A, ...

Solitary bone lesion may be amenable through excision or limited radiation, dosage of 5-10 Gy for children, 24-30 Gy for adults ... Recurrent cytogenetic or genomic abnormalities would also be required to demonstrate convincingly that LCH is a malignancy.[ ... is an endocytic receptor that induces the formation of Birbeck granules". Immunity. 12 (1): 71-81. doi:10.1016/S1074-7613(00) ... "Hypothalamo-pituitary abnormalities in adult patients with langerhans cell histiocytosis: clinical, endocrinological, and ...

"Chemotherapy-Induced Nausea and Vomiting Treatment & Management". Medscape Reference. WebMD. 3 July 2012. Archived from the ... radiation pneumonitis, acute respiratory distress, etc. Swelling of the pancreas Swelling of the stomach Formation of a hole in ... Swelling of the bile duct A potentially fatal skin reaction A fairly benign form of skin cancer A potentially fatal abnormality ... See BRAF (gene)#Sorafenib for details the drug's interaction with B-Raf.) Sorafenib treatment induces autophagy, which may ...

When managing leiomyomas, radiation treatment should be avoided due to the inducing effect of malignant transformation in the ... Abnormalities of these genes may initiate the formation or growth of these tumors. Modification of signaling pathways and genes ...

Hypercoagulability is an abnormality of the blood that increases the risk of the formation blood clots. Nephrotic syndrome ... It is non-invasive, fast and avoids radiation (unlike a CT scan) but it is relatively expensive. MRA produces detailed images ... Infants and young children experiencing dehydration induced RVT, may experience dehydration symptoms (dry mouth, low urine ... Dehydration may be caused by reduction in both volume and circulatory blood volume due to water depleting abnormalities like ...

... the relationship between folate breakdown induced by ultraviolet radiation and reduced fitness as a failure of normal ... In these abnormalities children are born with an incomplete brain or spinal cord. Nina Jablonski, a professor of anthropology ... dark skin does not increase the body's internal heat intake in conditions of intense solar radiation. Solar radiation heats up ... While high UV radiation can cause skin cancer, the development of cancer usually occurs after child-bearing age. As natural ...

A pregnancy may end in a live birth, a miscarriage, an induced abortion, or a stillbirth. Childbirth typically occurs around 40 ... The underlying cause in about half of cases involves chromosomal abnormalities. Stillbirth is defined as fetal death after 20 ... Projectional radiography, CT scan and nuclear medicine imaging result in some degree of ionizing radiation exposure, but in ... Therefore, in an otherwise uncomplicated pregnancy, obstetricians usually prefer to induce labour at some stage between 41 and ...

The vibration of the diaphragm may be measured or induced electronically using the capacitance between the diaphragm and a ... It is substantially lower in cost than other imaging strategies and does not use harmful ionizing radiation. Drawbacks include ... Srivastav, A.; Bhogi, K.; Mandal, S.; Sharad, M. (Aug 2019). "An Adaptive Low-Complexity Abnormality Detection Scheme for ... These miniature devices continuously monitor vitals and alert at the emergence of early signs of abnormality. Ultrasonic ...

... that can sense radioactive plumes from nuclear plants have detected plumes several kilometers away based on radiation-induced ... use of THz waves for non-destructive evaluation enables inspection of multi-layered structures and can identify abnormalities ... Active systems illuminate the subject with THz radiation whereas passive systems merely view the naturally occurring radiation ... Because THz radiation is biologically safe (non ionisant), it can be used in high resolution imaging to detect skin cancer. ...

UNSCEAR raised the possibility of long term genetic defects, pointing to a doubling of radiation-induced minisatellite ... a dose much lower than that which it was determined would induce embryonic abnormalities or other non-stochastic effects, there ... The United Nations Scientific Committee on the Effects of Atomic Radiation has estimated a global collective dose of radiation ... Workers at Forsmark reported the case to the Swedish Radiation Safety Authority, which determined that the radiation had ...

TOS can be attributed to one or more of the following factors: Congenital abnormalities are frequently found in persons with ... The "compression test" is also used, exerting pressure between the clavicle and medial humeral head causes radiation of pain ... This rudimentary rib causes fibrous changes around the brachial plexus nerves, inducing compression and causing the symptoms ... These include cervical rib, prolonged transverse process, and muscular abnormalities (e.g., in the scalenus anterior muscle, a ...

Staurosine-induced cell death has been shown to influence caspase-1 to initiate the cleavage of SphK2. In other forms of ... Cell damage can occur through environmental factors such as air pollution, UV radiation from the sun, or physical injury. In ... and developmental abnormalities have been shown to occur. As long as the engulfment process is functioning and efficient, ... Apoptosis causes a dimerization of S19, inducing a conformation change that allows it to bind to the C5a receptor on monocytes ...

It is a SMO antagonist that can induce arrest of cell division and promote apoptosis in cancer cells. Sonidegib has been ... Sonidegib can also be used in BCC patients who are not candidates for surgery or radiation therapy. Effectiveness of this drug ... Gorlin syndrome is an autosomal dominant disorder characterized by developmental abnormalities and increased risk of developing ... It is also used for treating patients with locally advanced BCC who are not candidates for surgery or radiation therapy. ...

Researchers suspect that these neurological abnormalities are due to the accumulation of DNA damage despite the brain not being ... Ultraviolet rays emerging from the sun, various hazardous chemicals, harmful radiations, are all known parameters for the ... Such damages include bulky chemical adducts, ultraviolet-induced pyrimidine dimers, and several forms of oxidative damage. ...

... of accumulated radiation exposures and residents who were evacuated were exposed to so little radiation that radiation-induced ... 2015). "Commentary 2: abnormalities of butterflies captured around Fukushima areas might not be caused by non-genetic but toxic ... The risks from a number of additional radiation-induced cancers are also expected to be elevated. There is an estimated 7% ... Radiation exposure of those living in proximity to the accident site is expected to be below 10 mSv, over the course of a ...

This technique allows abnormalities such as deletions and duplications to be revealed. Chemical tags have been tailored for ... Moreover, radiation and appropriate handling is no longer a concern. With the development of fluorescent tagging, fluorescence ... When this peptide is inserted into the organism's cell, it can induce a different reaction. This method can be used, for ... Fluorescence in 1852 which states that the wavelength of fluorescence emission is greater than that of the exciting radiation. ...

... chemotherapy induced alopecia, telogen effluvium, and traction alopecia. Redensyl Redensyl is emerging as an alternative hair ... seen in hair shaft abnormalities). Fungal Culture Scalp is scraped and the specimen is incubated for fungal growth commonly ... cancer treatments such as radiation and alkylating agents Dermatopathia pigmentosa reticularis: genetic autosomal dominant ... history cancer treatments such as radiation and alkylating agents Dermatopathia pigmentosa reticularis: genetic autosomal ...

... indicated that the residents of the area who were evacuated were exposed to little radiation and that radiation induced health ... TEPCO did not indicate what would be done if abnormalities were spotted during the tests. Within the primary containment of ... Radiation levels of 0.8 mSv per hour were found, almost as high as the radiation levels outside the homes. None of these ... Radiation above this level increases the risk of cancer, and after 400 mSv radiation poisoning can occur, but is unlikely to be ...

Latonen L, Taya Y, Laiho M (October 2001). "UV-radiation induces dose-dependent regulation of p53 response and modulates p53- ... These studies suggest Chk1 depletion can lead to defects in the spindle checkpoint resulting in mitotic abnormalities. DNA ... WEE1 kinase and PLK1 are also targeted by Chk1 to induce cell cycle arrest. Phosphorylation of WEE1 kinase inhibits cdk1 which ... Chk1 is essential for cell survival and through high levels of expressions in tumors the function may be inducing tumor cell ...

Neuroprotective therapies for radiation-induced brain injury are still limited. In a mouse model of brain radiation, ShK-170 ... no grade 3 or 4 adverse effects or laboratory abnormalities were noted, and the predicted range of drug exposures were achieved ... Ovalbumin-induced delayed type hypersensitivity and oxazolone-induced dermatitis are considered to be models of atopic ... and protected neurons from radiation-induced brain injury by suppressing microglia. ShK peptide has a low toxicity profile in ...

For weak bonds, homolysis can be induced thermally. Strong bonds require high energy photons or even flames to induce homolysis ... Radicals may be generated in a number of ways, but typical methods involve redox reactions, Ionizing radiation, heat, ... skin pigmentary melanin abnormalities, deafness, arthritis, and diabetes mellitus. The free-radical theory of aging proposes ... Because radicals are necessary for life, the body has a number of mechanisms to minimize radical-induced damage and to repair ...

This procedure minimises the incision size and reduces the recovery time and risk of surgery induced astigmatism. It is best ... Recent testing has shown that ultrasound can increase the effectiveness of cancer treatments such as chemotherapy and radiation ... Images can be used to examine the flow of blood through specific vessels and examine if there is any blockage or abnormalities ...

They have physical abnormalities including a large head (macrocephaly), sparse hair, prominent scalp veins, inward-folded ... Bregman, DB; Halaban, R; Van Gool, AJ; Henning, KA; Friedberg, EC; Warren, SL (1996). "UV-induced ubiquitination of RNA ... radiation, depurination, and deamination.[citation needed] Mutations in three classes of DNA repair proteins, RecQ protein-like ... Other symptoms include scaly skin, abnormalities of the fingernails and toenails, clouding of the lens of the eye from birth ( ...

Treatment includes radiation and chemotherapy. Early-stage indolent B-cell lymphomas can often be treated with radiation alone ... Chromosomal translocations involving the immunoglobulin heavy locus is a classic cytogenetic abnormality for many B-cell ... now induces massive transcription of the fusion protein, resulting in excessive pro-proliferative or anti-apoptotic effects on ... Early-stage aggressive disease is treated with chemotherapy and often radiation, with a 70-90% cure rate. Late-stage indolent ...

Radiographic examinations involve radiation exposure in the form of X-rays. Although barium ions are toxic, their use is ... It has poor sensitivity for subtle abnormalities but is more sensitive in detecting esophageal webs and rings than gastroscopy ... Hypersensitivity and allergic reactions are rare but some additives contained in barium preparations may induce immune ... This can be unpleasant to the subject, requires more staff, longer procedural time, and higher radiation dose when compared to ...

... cells of irradiated mice with very low-dose rate of chronic gamma-irradiation and its biological influence on radiation-induced ... Detection of chromosomal abnormalities can be found in utero for certain diseases by means of blood samples or ultrasound, as ... This editing system induces a double stranded break in the DNA, using a guide RNA and effector protein Cas9 to break the DNA ... By inducing a double stranded break in sequences surrounding the disease-causing point mutation, a dividing cell can use the ...

Radiation, chemotherapy, and in some cases, surgery, is used to treat cancer. The following are the most common types of cancer ... Physiological abnormalities associated with AD include neurofibrillary plaques and tangles. Neuritic plaques, that target the ... Cardiovascular diseases include a variety of heart conditions that may induce a heart attack or other heart-related problems. ... perhaps due to the stress induced by these conditions. In older adults, depression presents as impairments already associated ...

... and chemotherapy-induced acral erythema. Lab abnormalities associated with sunitinib therapy include lipase, amylase, ... Renal cell carcinoma is generally resistant to chemotherapy or radiation. Prior to RTKs, metastatic disease could only be ... Patients with mRCC and sunitinib-induced hypertension had better outcomes than those without treatment-induced HTN (objective ... Like renal cell carcinoma, gastrointestinal stromal tumor does not generally respond to standard chemotherapy or radiation. ...

The spectrum of drug-induced liver alterations is broad and encompasses the whole range of hepatic abnormalities. The incidence ... In the [radiation therapy (RT)] plus [anti-androgen Therapy (AAT)] arm Grade III was the highest liver toxicity observed which ... n\n] Drug-induced changes were more likely when liver function test values were above the ULN at more than one assessment. This ... Ikemoto I, Kiyota H, Abe K, Hasegawa T, Ohishi Y, Aizawa Y (20 May 2000), "ビカルタミドにより惹起された重症肝障害" [Bicalutamide-induced Liver ...

Head and neck lymphedema can be caused by surgery or radiation therapy for tongue or throat cancer. It may also occur in the ... GATA2 deficiency-induced defects in the lymphatic vessels and valves underlies the development of lymphedema, primarily in the ... Some cases of lymphedema may be associated with other vascular abnormalities.[citation needed] Secondary lymphedema affects ... Radiation Therapy Oncology Group". The Prostate. 5 (5): 471-476. doi:10.1002/pros.2990050502. PMID 6483687. S2CID 36177502. ...

Specific cytogenetic abnormalities can be found in many people with AML; the types of chromosomal abnormalities often have ... The first-line treatment of AML is usually chemotherapy, with the aim of inducing remission. People may then go on to receive ... High amounts of ionizing radiation exposure, such as that used for radiotherapy used to treat some forms of cancer, can ... Certain cytogenetic abnormalities are associated with very good outcomes (for example, the (15;17) translocation in APL). About ...

"Topical application of the synthetic triterpenoid RTA 408 protects mice from radiation-induced dermatitis". Radiation Research ... Cardiac abnormalities can be controlled with ACE inhibitors such as enalapril, ramipril, lisinopril, or trandolapril, sometimes ... October 1996). "Clinical and genetic abnormalities in patients with Friedreich's ataxia". The New England Journal of Medicine. ... October 1996). "Clinical and genetic abnormalities in patients with Friedreich's ataxia". The New England Journal of Medicine. ...

CS Type I, the "classic" form, is characterized by normal fetal growth with the onset of abnormalities in the first two years ... DNA damage is caused by ultraviolet rays from sunlight, radiation, or free radicals in the body. A normal cell can repair DNA ... CSA and CSB deficient cells are unable to preferentially repair cyclobutane pyrimidine dimers induced by the action of ... The eyes of patients can be affected in various ways and eye abnormalities are common in CS. Cataracts and cloudiness of the ...

In addition, chlornaphazine induces chromosomal abnormalities in erythrocytes in both mouse and rat bone marrow. It has been ... To patients who became resistant to radiation, nitrogen mustards such as chlornaphazine could be administered. In patients with ... Like in humans, 2-naphthylamine induces bladder tumors in dogs, monkeys, and hamsters. Bladder cancer can be induced in rats, ... 1969). "BLADDER TUMOURS INDUCED BY CHLORNAPHAZINE: A Five-year Follow-up Study of Chlornaphazine-treated Patients with ...