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*  Antagomir
Blockmirs bind on the 3' end of the untranslated region (UTR) of the mRNA strand, which adequately blocks microRNA from binding ... as most microRNAs do not bind to the translated region. Antagomirs are used as a method to constitutively inhibit the activity ... 354 (11): 1194-5. doi:10.1056/NEJMcibr060065. PMID 16540623. Adam O, Löhfelm B, Thum T, Gupta SK, Puhl SL, Schäfers HJ, Böhm M ... 107 (5): 278. doi:10.1007/s00395-012-0278-0. PMID 22760500. Pandit KV, Corcoran D, Yousef H, Yarlagadda M, Tzouvelekis A, ...
*  Exon
Exitron Exon shuffling Interrupted gene Intron mRNA Untranslated region (UTR) Gilbert W (February 1978). "Why genes in pieces ... untranslated regions (UTR). Often the first exon includes both the 5′-UTR and the first part of the coding sequence, but exons ... for intragenic regions) - alternating with regions which will be expressed - exons." This definition was originally made for ... The term exon derives from the expressed region and was coined by American biochemist Walter Gilbert in 1978: "The notion of ...
*  HNRPD
... untranslated region binds AUF1 and heat shock protein 27". J. Biol. Chem. 277 (49): 47061-72. doi:10.1074/jbc.M202272200. PMID ... 311 (5): 973-88. doi:10.1006/jmbi.2001.4862. PMID 11531333. Lapucci A, Donnini M, Papucci L, Witort E, Tempestini A, Bevilacqua ...
*  Three prime untranslated region
... untranslated region, 3' untranslated region, and the poly(A) tail. The 3'-UTR often contains regulatory regions that post- ... Regulatory regions within the 3'-untranslated region can influence polyadenylation, translation efficiency, localization, and ... untranslated region also has regulatory functions. Protein factors can either aid or disrupt folding of the region into various ... Five prime untranslated region UTRdb UTRome Barrett, Lucy W.; Fletcher, Sue; Wilton, Steve D. (27 April 2012). "Regulation of ...
*  Let-7 microRNA precursor
In a twist, there are let-7-binding sites in MYC 3' untranslated region(UTR) according to bioinformatic analysis, and let-7 ... untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with ... untranslated region of HMGA2 mRNA in uterine leiomyomas". Cancer Genet Cytogenet. 196 (2): 119-23. doi:10.1016/j.cancergencyto. ... untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan". ...
*  OSER1
... untranslated region 252 bp long. 3' untranslated region 1,129 bp long. 10 splice isoforms that encode good proteins, altogether ... In this same region of the promoter, there is also a TATA-binding factor sequence, which helps in the positioning of RNA ... The protein is highly conserved in the DUF776 region amongst vertebrates, and also at the C-terminus in eukaryotes. Using tools ... 294 (5): 1351-62. doi:10.1006/jmbi.1999.3310. PMID 10600390. Human OSER1 genome location and OSER1 gene details page in the ...
*  Osteopontin
... untranslated region (5' UTR). Exons 2, 3, 4, 5, 6, and 7 code for 17, 13, 27, 14, 108 and 134 amino acids, respectively. All ... 28 (7): 1492-5. PMID 11469452. Nagasaka A, Matsue H, Matsushima H, Aoki R, Nakamura Y, Kambe N, Kon S, Uede T, Shimada S ( ... 154 (3): 671-5. doi:10.1016/S0002-9440(10)65313-8. PMC 1866412 . PMID 10079244. Choi ST, Kim JH, Kang EJ, Lee SW, Park MC, Park ... 61 (1): 251-5. doi:10.1016/j.cyto.2012.10.002. PMID 23098767. Samitas K, Zervas E, Xanthou G, Panoutsakopoulou V, Gaga M (Feb ...
*  Heat shock protein 70 (Hsp70) internal ribosome entry site (IRES)
... untranslated region of human hsp70 mRNA". J Biol Chem. 278 (25): 22350-22356. doi:10.1074/jbc.M303213200. PMID 12682055. Page ... It has been shown that the 216 nucleotide long 5' UTR contains internal ribosome entry site activity. Rubtsova, MP; Sizova DV; ... Dmitriev SE; Ivanov DS; Prassolov VS; Shatsky IN (2003). "Distinctive properties of the 5'- ...
*  Collagen, type VI, alpha 2
... untranslated region generated by an alternate exon". J. Biol. Chem. 267 (9): 6188-96. PMID 1556127. Dawson SJ, White LA (1992 ... 1992). "The exon organization of the triple-helical coding regions of the human alpha 1(VI) and alpha 2(VI) collagen genes is ... 14 (1): 113-5. doi:10.1038/ng0996-113. PMID 8782832. Tillet E, Ruggiero F, Nishiyama A, Stallcup WB (1997). "The membrane- ...
*  KLF9
... untranslated region". J. Biol. Chem. 269 (32): 20668-73. PMID 8051167. Imataka H, Mizuno A, Fujii-Kuriyama Y, Hayami M (1994 ... Regions around 10 kb upstream and 1 kb downstream of Klf9 transcription start site contain conserved antioxidant response ... a GC box sequence in the promoter region of the rat P-4501A1 gene". EMBO J. 11 (10): 3663-71. PMC 556826 . PMID 1356762. " ... 117 (1): 91-5. PMID 7775404. Imataka H, Nakayama K, Yasumoto K, Mizuno A, Fujii-Kuriyama Y, Hayami M (1994). "Cell-specific ...
*  NuoG RNA motif
... untranslated regions of nuoG genes. This gene and the downstream genes probably comprise an operon that encodes various ...
*  RNA thermometer
... untranslated region (UTR) of messenger RNA encoding heat shock proteins-though it has been suggested this fact may be due, in ... untranslated region elements essential for preferential heat shock translation". J Biol Chem. 279 (48): 49919-49930. doi: ... Some RNA thermometers are significantly more complex than a single hairpin, as in the case of a region found in CspA mRNA which ... This structural transition can then expose or occlude important regions of RNA such as a ribosome binding site, which then ...
*  Hsp90 cis-regulatory element
... untranslated region elements essential for preferential heat shock translation". J Biol Chem. 279 (48): 49919-49930. doi: ... The Hsp90 cis regulatory element is an RNA element (RNA thermometer) found in the 5' UTR of the Drosophila hsp90 mRNA. It is ...
*  CMPK
... untranslated region". Life Sciences. 69 (20): 2361-70. doi:10.1016/S0024-3205(01)01322-4. PMID 11681623. Liou JY, Dutschman GE ... "Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library". Gene. 200 (1-2): 149-56. doi: ... "Characterization of human UMP-CMP kinase enzymatic activity and 5′ ...
*  Complement receptor 1
The transmembrane region is encoded by 2 exons and the cytoplasmic domain and the 3'-untranslated regions are coded for by two ... untranslated region are contained in one exon. The large extracellular domain of CR1, which has 25 potential N-glycosylation ... This gene is a member of the regulators of complement activation (RCA) family and is located in the 'cluster RCA' region of ... The promoter region lacks a distinct TATA box sequence. The gene is expressed principally on erythrocytes, monocytes, ...
*  INAVA
... untranslated region is shown. Isoform 1, diagramed below, contains a DUF3338 domain, two low complexity regions and a proline ... The factors that are predicted to bind to the promoter region of isoform 2 differ, and twelve of the top twenty predicted ... A total of 556 single nucleotide polymorphisms (SNPs) have been identified in the gene region of INAVA, 96 of which are ... A diagram of the predicted promoter region, with highlighted transcription factor binding sites, is shown to the right. ...
*  CGB1
... untranslated region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however ... 267 (5): 3179-84. PMID 1371113. Policastro PF, Daniels-McQueen S, Carle G, Boime I (1986). "A map of the hCG beta-LH beta gene ... The CGB genes are primarily distinguished by differences in the 5' ...
*  UCK2
... untranslated region". Life Sci. 69 (20): 2361-70. doi:10.1016/S0024-3205(01)01322-4. PMID 11681623. Liou JY, Dutschman GE, Lam ... 12 (5): 751-64. doi:10.1016/j.str.2004.02.038. PMID 15130468. Murata D, Endo Y, Obata T, et al. (2005). "A crucial role of ... 12 (5): 751-764. doi:10.1016/j.str.2004.02.038. Appleby, Todd C.; Larson, Gary; Cheney, I. Wayne; Walker, Heli; Wu, Jim Z.; ... 21 (5): 566-9. doi:10.1038/nbt810. PMID 12665801. Pasti C, Gallois-Montbrun S, Munier-Lehmann H, et al. (2003). "Reaction of ...
*  Iron response element
... untranslated regions) of various mRNAs whose products are involved in iron metabolism. For example, the mRNA of ferritin (an ... untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy". The Journal of ... untranslated region". Proceedings of the National Academy of Sciences of the United States of America. 84 (23): 8478-8482. doi: ... untranslated region". The Journal of Biological Chemistry. 270 (51): 30781-30786. doi:10.1074/jbc.270.51.30781. PMID 8530520. N ...
*  Coxsackie B4 virus
... untranslated region contains an internal ribosomal entry site (Type I IRES). Covalently bonded to the 5' UTR is the viral ... untranslated region and encodes its own 3' poly-A tail. The 5' ... The VPg protein that is covalently linked to the 5' end of the ... Upon entry of the genome into the cytoplasm of the host cell, the IRES in the 5' UTR recruits ribosomal subunits (cap- ... Its genome is linear and is 7,293 nucleotides in length with both a 5' and 3' ...
*  MraW RNA motif
... untranslated regions of mraW genes. These mraW genes likely form operons with immediately downstream ftsI genes, and multiple ... mraW RNAs are consistently in the presumed 5' ...
*  ATF5
... untranslated region". J. Biol. Chem. 283 (5): 2543-2553. doi:10.1074/jbc.M707781200. PMID 18055463. ATF5 protein, human at the ... Al Sarraj J, Vinson C, Thiel G (2005). "Regulation of asparagine synthetase gene transcription by the basic region leucine ... Activating transcription factor 5, also known as ATF5, is a protein that, in humans, is encoded by the ATF5 gene. First ... 20 (5): 942-948. doi:10.1016/j.cellsig.2008.01.010. PMID 18276110. Pati D, Meistrich ML, Plon SE (1999). "Human Cdc34 and Rad6B ...
*  Michael Stuart Brown
... untranslated regions". Cell. 38 (1): 275-85. doi:10.1016/0092-8674(84)90549-X. PMID 6088070. Yamamoto T, Davis CG, Brown MS, et ... Yamamoto T, Bishop RW, Brown MS, Goldstein JL, Russell DW (Jun 1986). "Deletion in cysteine-rich region of LDL receptor impedes ... "Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region". Nature. 326 (6115 ... 76 (5): 865-73. doi:10.1016/0092-8674(94)90361-1. PMID 8124722. Wang X, Sato R, Brown MS, Hua X, Goldstein JL (Apr 1994). " ...
*  GlmS glucosamine-6-phosphate activated ribozyme
... untranslated regions of glmS genes. The GlmS enzyme catalyzes the production of glucosamine-6-phosphate (GlcN6P), and the glmS ... It was originally identified using bioinformatics in the 5' ...
*  AXIN2
... untranslated regions of its mRNA". J. Biol. Chem. 280 (9): 8581-8. doi:10.1074/jbc.M410806200. PMID 15611123. Hughes TA, Brady ... The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, ... 74 (5): 1043-50. doi:10.1086/386293. PMC 1181967 . PMID 15042511. Mostowska A, Biedziak B, Jagodzinski PP (2006). "Axis ... Hughes TA, Brady HJ (2005). "Expression of axin2 is regulated by the alternative 5'- ...
*  UTRdb
... untranslated sequences of eukaryotic mRNAs Five prime untranslated region Three prime untranslated region UTRome Grillo, ... a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs". Nucleic Acids Res. 38 (Suppl_ ...
*  Mnt IRES
... untranslated region of the mnt gene". Oncogene. 20 (7): 893-897. doi:10.1038/sj.onc.1204157. PMID 11314024. Page for Mnt IRES ... N-myc IRES Tobamovirus IRES TrkB IRES Stoneley, M; Spencer JP; Wright SC (2001). "An internal ribosome entry segment in the 5' ...