Loading...
*  Succinic semialdehyde dehydrogenase deficiency
Under normal conditions, SSADH works with the enzyme GABA transaminase to convert GABA to succinic acid. Succinic acid can then ... Vigabatrin is an irreversible inhibitor of GABA transaminases which leads to decreased levels of GHB and elevation of GABA. ... Parviz, M.; Vogel, K.; Gibson, K.M.; Pearl, P.L. (2014). "Disorders of GABA Metabolism: SSADH and GABA-transaminase ... The absence of SSADH leads to a 30-fold increase of GHB and a 2-4 fold increase of GABA in the brains of patients with SSADH ...
*  4-aminobutyrate transaminase
Aurich, Harald (1961). "Über die β-Alanin-α-Ketoglutarat-Transaminase aus Neurospora crassa" [On the beta-alanine-alpha- ... Scott, E. M; Jakoby, W. B (1959). "Soluble γ-Aminobutyric-Glutamic Transaminase from Pseudomonas fluorescens". The Journal of ... Gibson, K; Vogel, Kara; Parviz, Mahsa; Pearl, Phillip (2015). "Disorders of GABA metabolism: SSADH and GABA-transaminase ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ...
*  4-aminobutyrate-pyruvate transaminase
... pyruvate transaminase (EC 2.6.1.96, aminobutyrate aminotransferase, gamma-aminobutyrate aminotransaminase, gamma-aminobutyrate ... aminobutyrate transaminase, GABA aminotransferase, GABA transaminase, GABA transferase, POP2 (gene)) is an enzyme with ... gamma-aminobutyric acid pyruvate transaminase, gamma-aminobutyric acid transaminase, gamma-aminobutyric transaminase, 4- ... and potential functions for an Arabidopsis γ-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate". J. Exp. ...
*  4-aminobutyrate aminotransferase
... may refer to: 4-aminobutyrate transaminase, an enzyme 4-aminobutyrate-pyruvate transaminase, ...
*  Gamma-aminobutyric acid aminotransferase
... may refer to: 4-aminobutyrate-pyruvate transaminase, an enzyme 4-aminobutyrate ... transaminase, an enzyme. ...
*  Rosmarinic acid
... is a potential anxiolytic as it acts as a GABA transaminase inhibitor, more specifically on 4-aminobutyrate ... using an in vitro measure of GABA transaminase activity. Awad R, Muhammad A, Durst T, Trudeau VL and Arnason JT, Phytother Res ... transaminase. Rosmarinic acid also inhibits the expression of indoleamine 2,3-dioxygenase via its cyclooxygenase-inhibiting ... Thus, chemically, rosmarinic acid is an ester of caffeic acid with 3,4-dihydroxyphenyllactic acid, but biologically, it is ...
*  Gamma-Aminobutyric acid
GABA reuptake inhibitors: deramciclane, hyperforin, tiagabine.[citation needed] GABA-transaminase inhibitors: gabaculine, ... GABA-transaminase) deficiency Dawson RM, Elliot DC, Elliot WH, Jones KM, eds. (1959). Data for Biochemical Research. Oxford: ... transaminase genes in plants or Pseudomonas syringae reduce bacterial virulence". Plant J. 64 (2): 318-30. doi:10.1111/j.1365- ... GABA transaminase enzyme catalyzes the conversion of 4-aminobutanoic acid (GABA) and 2-oxoglutarate (α-ketoglutarate) into ...
*  List of MeSH codes (D08)
... leucine transaminase MeSH D08.811.913.477.700.550 --- l-lysine 6-transaminase MeSH D08.811.913.477.700.700 --- ornithine-oxo- ... beta-alanine-pyruvate transaminase MeSH D08.811.913.477.700.347 --- d-alanine transaminase MeSH D08.811.913.477.700.470 --- ... alanine transaminase MeSH D08.811.913.477.700.120 --- 2-aminoadipate transaminase MeSH D08.811.913.477.700.200 --- 4- ... aminobutyrate transaminase MeSH D08.811.913.477.700.225 --- aspartate aminotransferases MeSH D08.811.913.477.700.225.249 --- ...
*  GABA transaminase
... glycine GABA transaminase is targeted by multiple antiepileptic and analgesic drugs referred to as GABA transaminase inhibitors ... A GABA transaminase is an enzyme that catalyzes chemical reactions. There are two types of this enzyme: 4-aminobutyrate ... Sherif, Fathi M; Saleem Ahmed, S (1995). "Basic aspects of GABA-transaminase in neuropsychiatric disorders". Clinical ... transaminase, which catalyzes the chemical reaction: 4-aminobutanoate + 2-oxoglutarate ⇌ {\displaystyle \rightleftharpoons } ...
*  ABAT
Rainesalo S, Saransaari P, Peltola J, Keränen T (Mar 2003). "Uptake of GABA and activity of GABA-transaminase in platelets from ... Jeremiah S, Povey S (Jul 1981). "The biochemical genetics of human gamma-aminobutyric acid transaminase". Annals of Human ... Cohen BI (Dec 2001). "GABA-transaminase, the liver and infantile autism". Medical Hypotheses. 57 (6): 673-4. doi:10.1054/mehy. ... GABA-transaminase) deficiency". Journal of Inherited Metabolic Disease. 22 (4): 414-27. doi:10.1023/A:1005500122231. PMID ...
*  Gamma-aminobutyrate aminotransaminase
... may refer to: 4-aminobutyrate-pyruvate transaminase, an enzyme 4-aminobutyrate ... transaminase, an enzyme. ...
*  POP2
The Shadow and the Flame 4-aminobutyrate-pyruvate transaminase, an enzyme Pop 2 (mixtape), a 2017 mixtape by Charli XCX. ...
*  List of EC numbers (EC 2)
... aspartate transaminase EC 2.6.1.2: alanine transaminase EC 2.6.1.3: cysteine transaminase EC 2.6.1.4: glycine transaminase EC ... neamine transaminase EC 2.6.1.94: 2'-deamino-2'-hydroxyneamine transaminase EC 2.6.1.95: neomycin C transaminase EC 2.6.1.96: 4 ... aminobutyrate---pyruvate transaminase EC 2.6.1.97: archaeosine synthase EC 2.6.1.98: UDP-2-acetamido-2-deoxy-ribo-hexuluronate ... 6-trideoxyglucose transaminase EC 2.6.1.35: glycine-oxaloacetate transaminase EC 2.6.1.36: L-lysine 6-transaminase EC 2.6.1.37 ...
*  N6-acetyl-beta-lysine transaminase
In enzymology, a N6-acetyl-beta-lysine transaminase (EC 2.6.1.65) is an enzyme that catalyzes the chemical reaction 6-acetamido ... This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The ... conversion of 6-N-acetyl-L-beta-lysine to 3-keto-6-acetamidohexanoate and of 4-aminobutyrate to succinic semialdehyde by ... different transaminases". Arch. Biochem. Biophys. 197 (1): 226-35. doi:10.1016/0003-9861(79)90240-6. PMID 44448. Molecular and ...
*  Gabaculine
... a new potent inhibitor of gamma-aminobutyrate transaminase, on brain gamma-aminobutyrate content and convulsions in mice" (PDF ... Rando, Robert; Bangerter, F.W. (May 13, 1977). "The In Vivo Inhibition of GABA-transaminase by Gabaculine" (PDF). Biochemical ... gabaculine is extremely potent and toxic when compared to other GABA transaminase inhibitors, with an ED50 of 35 mg/kg and LD50 ... which acts as a potent and irreversible GABA transaminase inhibitor, and also a GABA reuptake inhibitor. Gabaculine is also ...
*  Succinic semialdehyde
It is formed from GABA by the action of GABA transaminase and further oxidised to become succinic acid, which enters TCA cycle ... Succinic semialdehyde dehydrogenase deficiency 4-aminobutyrate aminotransferase Lide, David R. (1998), Handbook of Chemistry ...
*  Succinate-semialdehyde dehydrogenase (NADP+)
... succinic semialdehyde transaminase gene (gabT) and characterization of the succinic semialdehyde dehydrogenase gene (gabD)". J ... 2 H+ This enzyme participates in the degradation of glutamate and 4-aminobutyrate. Bartsch, K.; von Johnn-Marteville, A.; ...
*  Aminooxyacetic acid
I. The inhibition of gamma-aminobutyric acid-alpha-ketoglutaric acid transaminase in vitro and in vivo by U-7524 (amino- ... Wolfgang Löscher; Dagmar Hönack; Martina Gramer (1989). "Use of Inhibitors of γ-Aminobutyric Acid (GABA) Transaminase for the ... Aminooxyacetic acid, often abbreviated AOA or AOAA, is a compound that inhibits 4-aminobutyrate aminotransferase (GABA-T) ... At concentrations high enough to fully inhibit 4-aminobutyrate aminotransferase activity, aminooxyacetic acid is indicated as a ...