18-Hydroxycorticosterone
... serves as an intermediate in the synthesis of aldosterone by the enzyme aldosterone synthase in the ... 18-Hydroxycortisol Aldosterone synthase Reddish MJ, Guengerich FP (August 2019). "Human cytochrome P450 11B2 produces ... 18-Hydroxycorticosterone is an endogenous steroid. It is a derivative of corticosterone. ... Izumi Y (July 2010). "[18-Hydroxycorticosterone (18-OH-B)]". Nihon Rinsho. Japanese Journal of Clinical Medicine (in Japanese ...
Familial hyperaldosteronism
18-Hydroxycortisol 18-Hydroxycorticosterone "Familial hyperaldosteronism". Genetics home reference. April 2014. Retrieved 8 ...
Congenital adrenal hyperplasia due to 17α-hydroxylase deficiency
Consequently, levels of DOC, corticosterone, and 18-hydroxycorticosterone are elevated. Although these precursors of ...
List of steroid abbreviations
18 (1): 117-24. doi:10.1046/j.1460-9568.2003.02734.x. PMID 12859344. S2CID 42753764. Labrie C, Simard J, Zhao HF, Belanger A, ... 2007). "Measurement of 18-Hydroxycorticosterone During Adrenal Vein Sampling for Primary Aldosteronism". Journal of Clinical ...
18-Hydroxycortisol
... is an endogenous steroid. 18-hydroxycortisol has been proposed as a biomarker for certain diseases. In ... Cortisol 18-Hydroxycorticosterone Aldosterone synthase Steroid 11β-hydroxylase 6β-Hydroxycortisol Lenders J, Williams T, ... In healthy subjects, the biosynthesis of 18-hydroxycortisol is low. The highest synthesis of 18-hydroxycortisol was found in ... Chiba H (July 2010). "18-Hydroxycortisol, 18-oxocortisol, and 6beta-hydroxycortisol". Nihon Rinsho. Japanese Journal of ...
Cortisol
18 (1): 41-78. doi:10.1089/vim.2005.18.41. PMC 1224723. PMID 15802953. Robson PJ, Blannin AK, Walsh NP, Castell LM, Gleeson M ( ... I 18-hydroxylation and 18hydroxy dehydrogenation. II beta-hydroxylation". Acta Endocrinol. 69 (4): I 701-717, II 718-730. doi: ... 18 (4): 301-9. PMID 3084123. Mikosha AS, Pushkarov IS, Chelnakova IS, Remennikov GY (1991). "Potassium Aided Regulation of ... "The effect of sodium deprivation and of angiotensin II infusion on the peripheral plasma concentrations of 18- ...
18-Hydroxy-11-deoxycorticosterone
In humans, 18-OH-DOC is a weak mineralocorticoid. It may be increased in 17α-hydroxylase (CYP17A1) deficiency, in aldosterone ... Excessive secretion of 18-OH-DOC can cause mineralocorticoid excess syndrome, although these cases are very rare. Fujii S, ... 18-hydroxydeoxycorticosterone at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Articles without ... 18-Hydroxy-11-deoxycorticosterone (also known as 18-OH-DOC, 18,21-dihydroxyprogesterone, and 18,21-dihydroxypregn-4-ene-3,20- ...
List of corticosteroids
18-hydroxypregn-4-ene-3,20-dione [5] 21-Deoxycortisol = 11β,17α-dihydroxypregn-4-ene-3,20-dione, 21-Deoxycortisone = 17α- ... 18,20-trione Corticosterone (17-deoxycortisol) = 11β,21-dihydroxypregn-4-ene-3,20-dione Cortisol (hydrocortisone) = 11β,17α,21- ... 18,21-dihydroxypregn-4-ene-3,20-dione [4] 18-Hydroxycorticosterone = 11β,18,21-trihydroxypregn-4-ene-3,20-dione 18- ...
Corticosterone 18-monooxygenase
In enzymology, a corticosterone 18-monooxygenase (EC 1.14.15.5) is an enzyme that catalyzes the chemical reaction ... "ENZYME - 1.14.15.5 corticosterone 18-monooxygenase". enzyme.expasy.org. Archived from the original on 2022-08-20. Retrieved ... "PhytoMine: GOTerm GO:0047783 corticosterone 18-monooxygenase activity GO". phytozome-next.jgi.doe.gov. Archived from the ... The systematic name of this enzyme class is corticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating ...
List of MeSH codes (D06)
18-hydroxydesoxycorticosterone MeSH D06.472.040.585.745 - pregnenolone MeSH D06.472.040.585.745.500 - 17-alpha- ... 18-hydroxycorticosterone MeSH D06.472.040.585.353.825 - tetrahydrocortisol MeSH D06.472.040.585.478 - 17-hydroxycorticosteroids ...
C21H30O5
... a corticosteroid 5α-Dihydroaldosterone Dihydrocortisone Hydrocortisone Humulone 18-Hydroxycorticosterone Isohumulone This set ...
List of MeSH codes (D04)
18-hydroxycorticosterone MeSH D04.808.745.745.654.252 - cortodoxone MeSH D04.808.745.745.654.339 - desoxycorticosterone MeSH ... D04.808.745.745.654.339.400 - 18-hydroxydesoxycorticosterone MeSH D04.808.745.745.654.473 - flurandrenolone MeSH D04.808. ...
Steroid 11β-hydroxylase
The weak 18-hydroxylase activity of CYP11B1 explains why an adrenal with suppressed CYP11B2 expression continues to synthesize ... Nicod J, Dick B, Frey FJ, Ferrari P (February 2004). "Mutation analysis of CYP11B1 and CYP11B2 in patients with increased 18- ... Fisher A, Friel EC, Bernhardt R, Gomez-Sanchez C, Connell JM, Fraser R, Davies E (September 2001). "Effects of 18-hydroxylated ... The CYP11B1 isozyme has strong 11β-hydroxylase activity, but the activity of 18-hydroxylase is only one-tenth of CYP11B2. ...
Aldosterone synthase
The 18-hydroxylase activity consists in catalyzing sequential hydroxylations of the steroid angular methyl group at C18. ... May 1997). "CMO I deficiency caused by a point mutation in exon 8 of the human CYP11B2 gene encoding steroid 18-hydroxylase ( ... Aldosterone synthase is the enzyme that has steroid 18-hydroxylase activity as well as steroid 11 beta-hydroxylase activity. ... The corticosterone methyl oxidase deficiencies both share this effect however type I causes an overall deficiency of 18- ...