The protein encoded by this gene is a member of the PTP family and PTPN14 subfamily of tyrosine protein phosphatases. PTPs are ... "Entrez Gene: PTPN14 protein tyrosine phosphatase, non-receptor type 14". Wadham C, Gamble JR, Vadas MA, Khew-Goodall Y (Jun ... Tyrosine-protein phosphatase non-receptor type 14 is an enzyme that in humans is encoded by the PTPN14 gene. ... Smith AL, Mitchell PJ, Shipley J, Gusterson BA, Rogers MV, Crompton MR (Apr 1995). "Pez: a novel human cDNA encoding protein ...
"Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ... Myosin phosphatase Rho-interacting protein is an enzyme that in humans is encoded by the MPRIP gene. M-RIP has been shown to ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355-64. doi: ... "Entrez Gene: M-RIP myosin phosphatase-Rho interacting protein". Gebbink MF, Kranenburg O, Poland M, van Horck FP, Houssa B, ...
La-related protein 1 (LARP1) is a 150 kDa protein that in humans is encoded by the LARP1 gene. LARP1 is a novel target of the ... LARP1 protein colocalizes with stress granules and P-bodies, which function in RNA storage and degradation. It has been ... LARP1 is the largest of a 7-member family of LARP proteins (others are: LARP1B, LARP3 (aka genuine La or SSB), LARP4A, LARP4B, ... Horke S, Reumann K, Schweizer M, Will H, Heise T (June 2004). "Nuclear trafficking of La protein depends on a newly identified ...
Proline-rich AKT1 substrate 1 (PRAS) is a protein that in humans is encoded by the AKT1S1 gene. GRCh38: Ensembl release 89: ... "PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase". Molecular Cell. 25 (6): 903-15. doi:10.1016/j.molcel. ... 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. Vander Haar E, Lee SI, Bandhakavi S, Griffin TJ, Kim DH (Mar ... 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. Huang B, Porter G (Oct 2005). "Expression of proline-rich Akt- ...
Rab GTPase-binding effector protein 1 is an enzyme that in humans is encoded by the RABEP1 gene. It belongs to rabaptin protein ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi: ... Hirst J, Lui WW, Bright NA, Totty N, Seaman MN, Robinson MS (Apr 2000). "A family of proteins with gamma-adaptin and VHS ... "Entrez Gene: RABEP1 rabaptin, RAB GTPase binding effector protein 1". Mattera R, Arighi CN, Lodge R, Zerial M, Bonifacino JS ( ...
This gene encodes a member of the GIT protein family. GIT proteins interact with G protein-coupled receptor kinases and possess ... a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein". Proceedings of the National ... phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins ... "The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo". The Journal of ...
NCK-interacting protein with SH3 domain is a protein that in humans is encoded by the NCKIPSD gene. The protein encoded by this ... "Entrez Gene: NCKIPSD NCK interacting protein with SH3 domain". Satoh S, Tominaga T (October 2001). "mDia-interacting protein ... "Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ...
14 (5): 543-8. doi:10.1038/sj.ejhg.5201577. PMID 16493448. S2CID 20931689. Bielas SL, Silhavy JL, Brancati F, Kisseleva MV, Al- ... 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325. Kong AM, Speed CJ, O'Malley CJ, Layton MJ, ... INPP5E is a phosphatidylinositol (3,4,5)-trisphosphate (PtdInsP3) and phosphatidylinositol 4,5-bisphosphate 5-phosphatase. Its ... and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". ...
Probable E3 ubiquitin-protein ligase MYCBP2 also known as myc-binding protein 2 or protein associates with myc (PAM) is an ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ... Guo Q, Xie J, Dang CV, Liu ET, Bishop JM (Sep 1998). "Identification of a large Myc-binding protein that contains RCC1-like ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355-64. doi: ...
Ankyrin repeat and SAM domain-containing protein 1A (ANKS1A), also known as ODIN, is a protein that in humans is encoded by the ... "ANKS1A - Ankyrin repeat and SAM domain-containing protein 1A - Homo sapiens (Human) - ANKS1A gene & protein". www.uniprot.org. ... Mass spectrometric analyses of Lck-purified proteins subsequently identified several proteins readily known as SFK kinase ... Kim J, Lee H, Kim Y, Yoo S, Park E, Park S (April 2010). "The SAM domains of Anks family proteins are critically involved in ...
The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to ... This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc ... "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): ...
FERM domain-containing protein 6 is a protein that in humans is encoded by the FRMD6 gene. GRCh38: Ensembl release 89: ... containing protein, 'Willin'" (PDF). FEBS Letters. 579 (22): 5089-94. doi:10.1016/j.febslet.2005.07.097. PMID 16137681. Jin J, ... "Differential tissue and subcellular expressionof ERM proteins in normal and malignant tissues: cytoplasmic ezrin expression has ... 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325. v t e (Articles with short description, Short ...
"A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957-68. doi:10.1016/j.cell ... ancient protein superfamily using motif search and structural modeling". Protein Sci. 3 (11): 2045-54. doi:10.1002/pro. ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-8. Bibcode:2005Natur. ... Elongation factor 1-gamma is a protein that in humans is encoded by the EEF1G gene. This gene encodes a subunit of the ...
FERM, RhoGEF and pleckstrin domain-containing protein 2 is a protein that in humans is encoded by the FARP2 gene. Model ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 5 (5): 277-86. ... "Entrez Gene: FARP2 FERM, RhoGEF and pleckstrin domain protein 2". "Salmonella infection data for Farp2". Wellcome Trust Sanger ... ARHGEF and pleckstrin domain-containing protein 2) at the PDBe-KB. v t e (Articles with short description, Short description ...
Joberty G, Petersen C, Gao L, Macara IG (Oct 2000). "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to ... "Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in ... "Nucleotide exchange factor ECT2 interacts with the polarity protein complex Par6/Par3/protein kinase Czeta (PKCzeta) and ... "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network". J. Biol. Chem. 279 ...
SHC SH2 domain-binding protein 1 is a protein that in humans is encoded by the SHCBP1 gene. SHCBP1 has been shown to interact ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi: ... "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173-1178. Bibcode: ... "Entrez Gene: SHCBP1 SHC SH2-domain binding protein 1". Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to ...
Rab11 family-interacting protein 5 is a protein that in humans is encoded by the RAB11FIP5 gene. RAB11FIP5 has been shown to ... Rab11FIP5 is one of the many proteins that have been shown to interact with the Rab11 protein. Rab GTPases, such as Rab11, are ... Some of the proteins that are regulated through Rab11FIP5 mediated vesicle trafficking are microtubule proteins and the TfR ... This leads to downstream changes with regards to which proteins can interact. This is a result of the various Rab11FIP proteins ...
Mylonis I, Giannakouros T (2003). "Protein kinase CK2 phosphorylates and activates the SR protein-specific kinase 1". Biochem. ... "Identification of SRPK1 and SRPK2 as the Major Cellular Protein Kinases Phosphorylating Hepatitis B Virus Core Protein". J. ... The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and ... Colwill K, Feng LL, Yeakley JM, Gish GD, Cáceres JF, Pawson T, Fu XD (1996). "SRPK1 and Clk/Sty protein kinases show distinct ...
Nck-associated protein 1 is a protein that in humans is encoded by the NCKAP1 gene. NCKAP1 has been shown to interact with RAC1 ... "Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac". The Biochemical Journal. 322 (Pt 3): 873-8. ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi: ... Matuoka K, Miki H, Takahashi K, Takenawa T (Oct 1997). "A novel ligand for an SH3 domain of the adaptor protein Nck bears an ...
"Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134 ... Ankycorbin is a protein that in humans is encoded by the RAI14 gene. Ankycorbin has been associated with the cortical actin ... protein". Biochem. Biophys. Res. Commun. 345 (4): 1333-41. doi:10.1016/j.bbrc.2006.04.184. PMID 16729964. Ewing RM, Chu P, ... a novel actin cytoskeleton-associated protein". Genes Cells. 5 (12): 1001-8. doi:10.1046/j.1365-2443.2000.00381.x. PMID ...
... +protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) Human CRTC3 genome location and ... "Identification of a family of cAMP response element-binding protein coactivators by genome-scale functional analysis in ... "Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle ... 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S ...
Supervillin is a protein that in humans is encoded by the SVIL gene. This gene encodes a bipartite protein with distinct amino ... Its function may include recruitment of actin and other cytoskeletal proteins into specialized structures at the plasma ... contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins ... F-actin-binding protein in the villin/gelsolin superfamily". The Journal of Cell Biology. 139 (5): 1255-69. doi:10.1083/jcb. ...
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in ... The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other ... a new class of nuclear mammalian proteins related to the yeast Mcm replication proteins". Nucleic Acids Res. 21 (23): 5289-93. ... The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate ...
Zinc finger and BTB domain-containing protein 21 is a protein that in humans is encoded by the ZBTB21 gene. GRCh38: Ensembl ... ZNF295+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text ... The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Research. 6 (5): 337-45. ... Wang J, Kudoh J, Takayanagi A, Shimizu N (Feb 2005). "Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is ...
The protein encoded by this gene is a member of the LAR protein tyrosine phosphatase-interacting protein (liprin) family. ... Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 has been shown to ... "Entrez Gene: PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 ... "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): ...
FUS-interacting serine-arginine-rich protein 1 is a protein that in humans is encoded by the SFRS13A gene. This gene product is ... which are important in mediating association with other cellular proteins. This protein can influence splice site selection of ... "TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins". Mol. Cell. Biol. 20 (10): 3345-54 ... "TLS-ERG leukemia fusion protein inhibits RNA splicing mediated by serine-arginine proteins". Mol. Cell. Biol. 20 (10): 3345-54 ...
2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. ... The EBV protein ENBA-LP binds to the CTPS1 promoter, along with MYC and NFκB, to enhance expression of CTPS1. SARS-CoV-2, the ... This step is unusual as it is catalysed by two homologous enzymes, CTPS1 and CTPS2, which share 74% homology at the protein ... Chang YF, Martin SS, Baldwin EP, Carman GM (June 2007). "Phosphorylation of human CTP synthetase 1 by protein kinase C: ...
Nakayama M, Kikuno R, Ohara O (Nov 2002). "Protein-protein interactions between large proteins: two-hybrid screening using a ... Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain". The Journal of Biological ... Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain". The Journal of Biological ... is a Rab GTPase-activating protein that in humans is encoded by the TBC1D4 gene. The 160 kD protein product was first ...
T-complex protein 1 subunit beta is a protein that in humans is encoded by the CCT2 gene. This gene encodes a molecular ... Overview of all the structural information available in the PDB for UniProt: P78371 (T-complex protein 1 subunit beta) at the ... This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the ... The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene ...
Serine/arginine repetitive matrix protein 2 is a protein that in humans is encoded by the SRRM2 gene. SRRM2 has been shown to ... "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/ ... The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 4 (2): 141-50. ... Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (2006). "A probability-based approach for high-throughput protein ...