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*  Zinc finger nuclease - Wikipedia
Zinc finger selector Zinc Finger Consortium website Zinc Finger Consortium materials from Addgene A commercial supplier of ZFNs ... can utilize either 1-finger or 2-finger modules to generate zinc-finger arrays with six or more individual zinc fingers. The ... Three zinc fingers are positioned in a semi-circular or C-shaped arrangement. Each zinc finger is made up of anti-parallel beta ... see: Zinc finger chimera for more info on zinc finger selection techniques) The non-specific cleavage domain from the type IIs ...
https://en.wikipedia.org/wiki/Zinc_finger_nuclease
*  Zinc finger inhibitor - Wikipedia
It ejects the zinc from the zinc binding sites in a two steps. The zinc in the carboxyl-terminal zinc finger is released first ... Zinc finger inhibitors, or zinc ejectors, are substances or compounds that interact adversely with zinc fingers and cause them ... This method of using zinc finger inhibitors to target and destabilize zinc fingers represents a new method of fighting HIV. ... residues on the zinc finger of the NCp7 and cause a covalent conformation change which ejects the zinc from the zinc finger ...
https://en.wikipedia.org/wiki/Zinc_finger_inhibitor
*  Evaluation of Novel Design Strategies for Developing Zinc Finger Nucleases Tools for Treating Human Diseases (Journal Article) ...
Zinc finger nucleases (ZFNs) are associated with cell death and apoptosis by binding at countless undesired locations. This ... Title: Evaluation of Novel Design Strategies for Developing Zinc Finger Nucleases Tools for Treating Human Diseases ... Published Article: Evaluation of Novel Design Strategies for Developing Zinc Finger Nucleases Tools for Treating Human Diseases ... Evolutionary success of natural zinc finger proteins, however, evinces that nature created specific evolutionary traits and ...
https://www.osti.gov/pages/biblio/1209764-evaluation-novel-design-strategies-developing-zinc-finger-nucleases-tools-treating-human-diseases
*  Isolation and Characterization of a Novel Zinc Finger Gene, ZNF219, and Mapping to the Human Chromosome 14q11 Region : DNA...
We have isolated and characterized a novel zinc finger gene by screening a human testis cDNA library. The isolated cDNA, termed ... Sequence analysis revealed 9 sets of Kruppel-related zinc finger structures and proline-rich regions in several parts. ZNF219 ... We have isolated and characterized a novel zinc finger gene by screening a human testis cDNA library. The isolated cDNA, termed ... Sequence analysis revealed 9 sets of Kruppel-related zinc finger structures and proline-rich regions in several parts. ZNF219 ...
http://oxfordindex.oup.com/view/10.1093/dnares/7.2.137
*  The Impact of Zinc on Human Health: The Essential Toxin - Ground Up Strength
In contrast, displacement of zinc from zinc-binding structures, e.g., finger structures in DNA repair enzymes, may even be a ... In addition to zinc sulfate, other zinc compounds like zinc oxide and zinc gluconate also have a similar impact on the ... Agren, M.S.; Krusell, M.; Franzen, L. Release and absorption of zinc from zinc oxide and zinc sulfate in open wounds. Acta ... It seems likely that zinc is also involved in neurodegenerative diseases, e.g., zinc and a deregulated zinc homeostasis could ...
http://www.gustrength.com/health:zinc-and-human-health
*  China 2015 Hot Sale Zinc Oxide Plaster for Hospital Use - China Zinc Oxide Tape, Surgical Tape
Find details about China Zinc Oxide Tape, Surgical Tape from 2015 Hot Sale Zinc Oxide Plaster for Hospital Use - Suzhou Texnet ... China 2015 Hot Sale Zinc Oxide Plaster for Hospital Use, ... finger, wrist.. Looking forward to your further ... Zinc Oxide Tape, Surgical Tape, Surgical Plaster Tape manufacturer / supplier in China, offering 2015 Hot Sale Zinc Oxide ... Zinc oxide tape is a very popular tape in domestic and foregin country,it has many different types and sizes for your ...
http://texnetmedical.en.made-in-china.com/product/oMUJhcFOlbWz/China-2015-Hot-Sale-Zinc-Oxide-Plaster-for-Hospital-Use.html
*  United States Monohydrate and Heptahydrate Zinc Sulfate Market Forecasts to 2021 and Analysis | Medgadget
Prosthetic Hand With Five Individually Controlled Fingers Lets Amputee Play Piano. Cheap Rehab System Powered by Kinect Camera ... 1.1 Product Overview and Scope of Monohydrate and Heptahydrate Zinc Sulfate. 1.2 Monohydrate and Heptahydrate Zinc Sulfate ... 1.3 Monohydrate and Heptahydrate Zinc Sulfate Segment by Application. 1.4 Monohydrate and Heptahydrate Zinc Sulfate Market by ... United States Monohydrate and Heptahydrate Zinc Sulfate Market Research Report 2016. 1 Monohydrate and Heptahydrate Zinc ...
https://www.medgadget.com/2017/02/united-states-monohydrate-and-heptahydrate-zinc-sulfate-market-forecasts-to-2021-and-analysis.html
*  Zinc fingers tagged stories - MIT Technology Review
The mission of MIT Technology Review is to bring about better-informed and more conscious decisions about technology through authoritative, influential, and trustworthy journalism.
https://www.technologyreview.com/g/zinc-fingers/
*  CRISPR: The End for Zinc Fingers?
Why is CRISPR better than zinc fingers?. ZFN and CRISPR/Cas9 systems function on a similar concept: a nuclease is steered ... One of the first breakthrough methods of gene targeting was the usage of chimeric proteins called zinc-fingers nucleases (ZFN) ... For example, there is no straightforward and easy way to construct zinc finger domains to bind a comprehensive stretch of ... The binding specificity of the designed zinc-finger domain points the ZFN to a specific genomic site. ...
https://www.news-medical.net/life-sciences/CRISPR-The-End-for-Zinc-Fingers.aspx
*  Zinc finger protein 630 (ZNF630)
zinc finger protein 484. X. laevis. 47.0. 431. NP_001137666.1 * Conserved domains (CDD) * * Gene summary * * Protein sequence * ... PREDICTED: zinc finger protein 135-like. D. rerio. 50.1. 411. NP_001086606.1 * Conserved domains (CDD) * * Gene summary * * ... Zinc finger protein 630 (ZNF630). Human protein-coding gene ZNF630. Represented by 31 ESTs from 21 cDNA libraries. Corresponds ... Homo sapiens zinc finger protein 630, mRNA (cDNA clone MGC:138344 IMAGE:8327607), complete cds. P. ...
https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=650883
*  Zinc finger protein 205 (O95201) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
http://www.ebi.ac.uk/interpro/protein/O95201
*  Targeted genome engineering via zinc finger nucleases | SpringerLink
Kim S, Lee MJ, Kim H, Kang M, Kim JS (2010b) Pre-assembled zinc finger arrays for rapid construction of zinc finger nucleases. ... Sander JD, Zaback P, Joung JK, Voytas DF, Dobbs D (2007) Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site ... Sander JD, Maeder ML, Reyon D, Voytas DF, Joung JK, Dobbs D (2010) ZiFiT (Zinc Finger Targeter): an updated zinc finger ... Porteus MH, Carroll D (2005) Gene targeting using zinc finger nucleases. Nat Biotechnol 23:967-973CrossRefPubMedGoogle Scholar ...
https://link.springer.com/article/10.1007%2Fs11816-010-0161-0
*  Genome Engineering With Zinc-Finger Nucleases | Genetics
Members of the Zinc Finger Consortium have recently derived fingers for some DNA triplets that work well in neighbor ... but not all fingers make equal contributions. More fingers can be added, and examples up to six fingers have been used. It is ... 1991 Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A resolution. Science 252: 809-817. ... Zinc fingers are shown as open boxes, with short vertical lines indicating the main contacts with the DNA base pairs. FokI ...
http://www.genetics.org/content/188/4/773?ijkey=778d38316f2d3bdf43bed1e02626f2975f87e63e&keytype2=tf_ipsecsha
*  Review of Zinc Fingers (9780822957249) - Foreword Reviews
Zinc Fingers: The best poems are the ones that call a reader to return again, conveying content through imagery, then going ...
https://www.forewordreviews.com/reviews/zinc-fingers/
*  Zinc-Finger Antiviral Protein Inhibits XMRV Infection
Background The zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039159
*  zinc finger (thing) by Halcyon&on - Everything2.com
The zinc finger is a sequence motif involved in binding of DNA: The C2H2 class cysteine,Cys-(Xaa)2-Cys-(Xaa)12-histidine,His-( ... zinc finger (thing). See all of zinc finger, there is 1 more in this node. ... The zinc finger is a sequence motif involved in binding of DNA: The C2H2 class. Cys-(Xaa)2-Cys-(Xaa)12-His-(Xaa)3-His. Xaa - ... The Cx class of zinc fingers have a variable number of cysteines that can chelate a Zn ion. These are also involved in DNA ...
https://everything2.com/user/Halcyon%2526on/writeups/zinc+finger
*  ZFBS - Zinc Finger Binding Site | AcronymFinder
ZFBS stands for Zinc Finger Binding Site. ZFBS is defined as Zinc Finger Binding Site very rarely. ... www.acronymfinder.com/Zinc-Finger-Binding-Site-(ZFBS).html. *Chicago style: Acronym Finder. S.v. "ZFBS." Retrieved December 17 ... www.acronymfinder.com/Zinc-Finger-Binding-Site-(ZFBS).html',ZFBS,/a,. ... www.acronymfinder.com/Zinc-Finger-Binding-Site-(ZFBS).html ... Zinc Finger Binding Proteins. *Zermelo-Fraenkel with Choice ( ...
https://www.acronymfinder.com/Zinc-Finger-Binding-Site-
*  ZFP7 - Zinc Finger Protein 7 | AcronymFinder
ZFP7 stands for Zinc Finger Protein 7. ZFP7 is defined as Zinc Finger Protein 7 somewhat frequently. ... www.acronymfinder.com/Zinc-Finger-Protein-7-(ZFP7).html. *Chicago style: Acronym Finder. S.v. "ZFP7." Retrieved April 21 2019 ... www.acronymfinder.com/Zinc-Finger-Protein-7-(ZFP7).html. *APA style: ZFP7. (n.d.) Acronym Finder. (2019). Retrieved April 21 ... www.acronymfinder.com/Zinc-Finger-Protein-7-(ZFP7).html',ZFP7,/a,. ...
https://www.acronymfinder.com/Zinc-Finger-Protein-7-
*  Zinc finger and BTB domain containing 42 (ZBTB42)
zinc finger protein 238.2. X. laevis. 61.2. 473. NP_001076421.1 * Conserved domains (CDD) * * Gene summary * * Protein sequence ... Homo sapiens zinc finger and BTB domain containing 42, mRNA (cDNA clone MGC:189728 IMAGE:9057052), complete cds. P. ... Homo sapiens zinc finger and BTB domain containing 42, mRNA (cDNA clone MGC:198537 IMAGE:9054476), complete cds. P. ... Zinc finger and BTB domain containing 42 (ZBTB42). Human protein-coding gene ZBTB42. Represented by 48 ESTs from 25 cDNA ...
https://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=170853
*  HIV gets the zinc finger
A zinc finger nuclease can be designed, for example, to specifically cut within the ccr5 gene. When the cell tries to repair ... One approach uses zinc finger nucleases, which are artificial proteins made by joining a protein that can specifically bind DNA ... This approach works: when CD4 T lymphocytes are removed from humans, cultured, and treated with a ccr5 zinc finger nuclease, ... treat the cells with the ccr5 zinc finger nuclease (delivered using an adenovirus vector), and infuse the cells back into the ...
http://www.virology.ws/2014/03/19/hiv-gets-the-zinc-finger/
*  When Zinc Fingers Miss the Mark | The Scientist Magazine┬«
When Zinc Fingers Miss the Mark. When Zinc Fingers Miss the Mark. Two new techniques identify how often zinc fingers nucleases ... Zinc Finger bound to DNAWIKIMEDIA COMMONS, THOMAS SPLETTSTOESSER. Zinc finger nucleases are designed to be like heat-seeking ... Zinc fingers, so named because their structure resembles a hand with a pointed finger, bind to different three-letter ... "As we begin to treat patients with zinc finger nucleases and modify genomes, we need to know where those modifications are ...
https://www.the-scientist.com/news-opinion/when-zinc-fingers-miss-the-mark-42101/amp
*  File:Zinc finger rendered.png
Cartoon representation of the zinc-finger motif of proteins. The zinc ion (green) is coordinated by two histidine and two ... Cartoon representation of the zinc-finger motif of proteins. The zinc ion (green) is coordinated by two histidine and two ...
http://schools-wikipedia.org/images/1188/118848.png.htm
*  Addgene: Zinc Finger Consortium Reagents
Find reagents for engineering and expressing zinc finger proteins deposited by Zinc Finger Consortium members like the Joung ... Zinc Finger Genome Engineering Reagents. *. Zinc Finger Arrays for Zebrafish Genes - Browse pre-constructed zinc fingers ... The Zinc Finger Consortium was established to promote continued research and development of engineered zinc finger technology. ... Oligomerized Pool ENgineering (OPEN) Reagents - Engineer zinc finger arrays via OPEN method ...
http://www.addgene.org/zfc/
*  Tailor-Made Mutations in Arabidopsis Using Zinc Finger Nucleases | SpringerLink
Zinc finger nucleases (ZFNs) are proteins engineered to make site-specific double-strand breaks (DSBs) in a DNA sequence of ... Sander JD et al (2010) ZiFiT (zinc finger targeter): an updated zinc finger engineering tool. Nucleic Acids Res 38:W462-W468 ... Kim S et al (2011) Preassembled zinc-finger arrays for rapid construction of ZFNs. Nat Methods 8:7PubMedCrossRefGoogle Scholar ... Osborn MJ et al (2011) Synthetic zinc finger nuclease design and rapid assembly. Hum Gene Ther 22:1155-1165PubMedCrossRefGoogle ...
https://link.springer.com/protocol/10.1007%2F978-1-62703-580-4_10
*  Efficient Gene Targeting in Drosophila With Zinc-Finger Nucleases | Genetics
... fingers. No attempt was made to optimize the affinity or specificity of the zinc-finger sets. All of the zinc-finger frameworks ... The sequence of the ZFN-targeted site is shown below with triplets bound by the zinc fingers in capital letters. Zinc fingers ... zinc-finger domains can be designed to target a broad range of DNA sequences. In fact, designed zinc-finger combinations have ... Another is redesigning the zinc fingers for greater specificity. An example of this approach is the use of additional fingers; ...
https://www.genetics.org/content/172/4/2391?ijkey=a186648410fe6c00f14337a06f535da083614625&keytype2=tf_ipsecsha