1996). "The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins". Nucleic ... Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein ... Y box binding protein 1 has been shown to interact with: ANKRD2, CTCF, P53, PCNA, RBBP6, and SFRS9. GRCh38: Ensembl release 89 ... "Entrez Gene: YBX1 Y box binding protein 1". Lage H, Surowiak P, Holm PS (November 2008). "[YB-1 as a potential target in cancer ...

... ... " " expressing spliced X-box-binding protein-1 (Xbp1s), a key effector of UPR signaling, in forebrain excitatory neurons, rapidly ... Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice. ... Sustained overexpression of spliced X-box-binding protein-1 in neurons leads to spontaneous seizures and sudden death in mice. ...

TATA-box-binding protein: K. Transcription initiation factor TFIID subunit 3: L. Transcription initiation factor TFIID subunit ... 5fur.1 , 5iy6.1 , 5iy7.1 , 5iy8.1 , 5iy9.1 , 5iya.1 , 5iyb.1 , 5iyc.1 , 5iyd.1 , 6mzc.1 , 6mzd.1 , 6mzl.1 , 6mzm.1 , 6o9l.1 , ... SMTL ID : 7ege.1 TFIID in canonical conformation Coordinates. PDB Format Method. ELECTRON MICROSCOPY Oligo State. hetero-1-1-2- ... Transcription initiation factor TFIID subunit 1: A. Transcription initiation factor TFIID subunit 2: B. Transcription ...

3TATA-box binding proteinTranscription initiation factor IIA large chain ... 1. 5-d(p*cp*gp*tp*tp*tp*tp*ap*tp*ap*tp*cp*gp*ap*tp*cp*gp*ap*t)-3 ... 1. 5-d(*ap*tp*cp*gp*ap*tp*cp*gp*ap*tp*ap*tp*ap*ap*ap*ap*cp*g)-3 ... 1RM1: Structure of a Yeast TFIIA/TBP/TATA-box DNA Complex. PDB ...

Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway.. Wang, Zhao V; Deng, ... Here, we show that spliced X-box binding protein 1 (Xbp1s), the most conserved signal transducer of the unfolded protein ... protein modifications. Despite the established role of the HBP in metabolism and multiple diseases, regulation of the HBP ... Proteína 1 de Unión a la X-Box ...

Hypoxia, in the context of the tumor microenvironment, is a critical ER stress that activates the unfolded protein response ( ... X-Box Binding Protein 1 * XBP1 protein, human * Iron Regulatory Protein 1 ... Hypoxia, in the context of the tumor microenvironment, is a critical ER stress that activates the unfolded protein response ( ... Targeting XBP-1 as a novel anti-cancer strategy Cancer Biol Ther. 2006 Jul;5(7):756-9. doi: 10.4161/cbt.5.7.2973. Epub 2006 Jul ...

XCL1 induces it chemotactic function by binding to a chemokine receptor called XCR1. ... In humans, XCL1 is closely related to another chemokine called XCL2, whose gene is found at the same locus on chromosome 1. ... Rat X-box-binding protein 1 (XBP1) ELISA Kit. Rat X-box-binding protein 1 (XBP1) ELISA Kit Views(539) Publications(0) Catalog ... Be the first to review "Rat X-box-binding protein 1 (XBP1) ELISA Kit" Cancel reply. You must be logged in to post a review. ...

The immune-related DEOSGs and hub genes were identified by weighted gene co-expression network analysis (WGCNA) and protein- ... protein interaction (PPI) analysis, respectively. Enrichment analysis was performed by Gene Ontology and Kyoto Encyclopedia of ... Forkhead box C1. CREB1:. Cyclic adenosine monophosphate responsive element-binding protein 1 ... GATA-binding protein 2 (GATA2) has been extensively studied in haematologica59,60, and recently recognized as a crucial TF in ...

Moreover, in dialysis RCC, Prx 3, 4, and 5 immunoreactivity and nuclear expression of Y-box-binding protein-1 were higher than ... Moreover, in dialysis RCC, Prx 3, 4, and 5 immunoreactivity and nuclear expression of Y-box-binding protein-1 were higher than ... Moreover, in dialysis RCC, Prx 3, 4, and 5 immunoreactivity and nuclear expression of Y-box-binding protein-1 were higher than ... Moreover, in dialysis RCC, Prx 3, 4, and 5 immunoreactivity and nuclear expression of Y-box-binding protein-1 were higher than ...

... chemokine binding protein; NMDAr, N-methyl D. -aspartate receptor-like protein. ... Gray boxes represent DNA sequence identity in the 2 genomes; black represents differences. The 2 large black boxes illustrate ... interleukin 18 binding protein; UL, ubiquitin ligase; IL1rAnt interleukin 1 receptor antagonist; EGF, epidermal growth factor; ... Segment boxes with dots indicate unknown genome sequences; TNFr, tumor necrosis factor receptor; U(fr), unknown fragment; ...

... unconventional splicing in the nucleus is most likely required for the maintaining of day-to-day folding protein homeostasis. ... The regulation of expression of X-box-binding protein-1 (XBP1), a transcriptional factor, involves an unconventional mRNA ... splicing of XBP1 mRNA in the nucleus that also requires inositol-requiring transmembrane kinase and endonuclease 1α (IRE1α) and ... Iwakoshi, N.N.; Lee, A.H.; Glimcher, L.H. The X-box binding protein-1 transcription factor is required for plasma cell ...

X-box-binding protein 1. Organism. Halocynthia aurantium [254849]. Cross Reference. UniProt. NULL. UniGene NULL. ... Protein. Program. Term. IPRS. Start. End. Score. Description. Haaura.CG.MTP2014.S1. Pfam. PF00170. IPR004827. 31. 85. 1.50e-09 ...

C/EBPhomologous protein expression (CHOP), immunoglobulin-heavy-chain-binding protein (BiP), sliced X-box-binding protein 1 ( ... X‑box‑binding protein 1 (XBP1) contributes to various types of cancer including breast, bladder cancer and esophageal squamous ... ER stress induces the splicing of X-box binding protein 1 (XBP1) to form its splicing variant XBP1-s, which in turn activates ... activation of signaling protein activity involved in unfolded protein response - DNA binding - endoplasmic reticulum unfolded ...

X-Box Binding Protein 1 Is Essential for Insulin Regulation of Pancreatic α-Cell Function  Akiyama, Masaru; Liew, Chong Wee; ... The protein kinase ERK5 (MAPK7) is an emerging drug target for a variety of indications, in particular for cancer where it ... The X-linked Intellectual Disability Protein PHF6 Associates with the PAF1 Complex and Regulates Neuronal Migration in the ... Mutations of the X-linked protein PHF6 cause the Börjeson-Forssman-Lehmann syndrome (BFLS) that is characterized ... ...

CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB ... CYCLIN; Cyclin box fold. Protein binding domain functioning in cell-cycle and transcription control. Present in cyclins, TFIIB ... Protein interactions. Protein. Gene. Interaction. Pubs. Vif vif HIV-1 Vif upregulates the expression of Cdk5 and Abl enzyme ... General protein information Go to the top of the page Help Preferred Names. CDK5 and ABL1 enzyme substrate 1. Names. interactor ...

... which also includes SRC-1 and SRC-2. Clinical and cell-based studies as well as investigations on mice have demonstrated ... which also includes SRC-1 and SRC-2. Clinical and cell-based studies as well as investigations on mice have demonstrated ... Decidualization and insulin-like growth factor (IGF) binding protein: implications for its role in stromal cell differentiation ... Illuminating the "black box" of progesterone-dependent embryo implantation using engineered mice. Front Cell Dev Biol. (2021) 9 ...

... a regulatory protein of X-box binding protein 1 (XBP-1) mRNA (21). Cleaved and activated ATF-6 p50 protein translocates to the ... Ca2+ binding proteins and folding enzymes such as calnexin, calreticulin and protein disulfide isomerase (PDI) are known to ... and protein concentrations were determined by the Bradford protein assay (BioRad). Total protein lysates (30 μg) were separated ... p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy. J Biol Chem. ...

X-box binding protein 1; UPR: unfolded protein response. ... heat shock protein family A (Hsp70) member 5; MAP1LC3B: ... Pau Muñoz-Guardiola 1 2 , Josefina Casas 3 , Elisabet Megías-Roda 1 2 , Sònia Solé 2 , Héctor Perez-Montoyo 2 , Marc Yeste- ... 1 , Sergio Espinosa-Gil 1 , Cristina Muñoz-Pinedo 4 , Guillermo Yoldi 1 , Jose L Abad 3 , Miguel F Segura 5 , Teresa Moran 6 , ... microtubule associated protein 1 light chain 3 beta; MEF: mouse embryonic fibroblast; MTORC1: mechanistic target of rapamycin ...

Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 ... Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-2M and A Glucocorticoid Receptor Interacting Protein 1 ... NR Box II Peptide. *PDB DOI: https://doi.org/10.2210/pdb2FAI/pdb ... Binding Affinity. 459. Binding MOAD: 2FAI Ki: 570 (nM) from ... These agonists are 10-50-fold selective for ERbeta in competitive binding assays and up to 60-fold selective in transactivation ...

TATA box binding protein (TBP) and β-actin. The primers used were 2A13-F (5′-acctggtgatgaccaccc-3′, located in exon 6) and 2A13 ... TATA box binding protein; bp, base pair(s); WT, wild-type; RFLP, restriction fragment length polymorphism; Tm, melting ... We have confirmed that there were no sequence variations at the primer or probe binding sites in any of the 16 samples (data ... A dramatic decrease in CYP2A13 protein levels will likely cause a significant decrease in the rate of NNK metabolic activation ...

TATA-box binding protein, Uniprot P20226; 0.22) and YWHAZ (14-3-3 protein zeta/delta, Uniprot P63104; 0.255). However, the more ... mitoribosomal proteins; GC = 0.138), and PCBP1 (an oligo-single-stranded-dC-binding protein) GC = 0.139). Clearly their ... RNA-binding protein 45. It is entirely reasonable that these might be expressed in all cells, and evidently at a fairly ... C-terminal-binding protein 1, Uniprot Q13363; 0.204) and GOLGA1 (Golgin subfamily A member 1, Uniprot Q92805; 0.189) (Lee et al ...

We illustrated several HDNetDB functionalities through a case study and identified proteins that constitute potential cross- ... talk between HD and the unfolded protein response (UPR). HDNetDB is publicly accessible at http://hdnetdb.sysbiolab.eu . ... In our case study, for instance, we excluded X-box binding protein 1 pseudogene 1 (XBP1P1). It was found because one of its ... In addition, we imported human protein-protein interactions from MDC55, CCSB56, HPRD57, DIP58, BIND59, BioGRID60, IntAct61, ...

Orange boxes highlight regulatory complement proteins. MBL: Mannose-binding lectin; MAC: Membrane attack complex; DAF: Decay ... C4b becomes membrane-bound and binds to pro-enzyme C2, which is then cleaved to C2a and C2b fragments by C1s. C2a remains bound ... The complement system is a biochemical cascade made up of approximately 30 serum and membrane-bound proteins and represents a ... C5b binds to C6 and C7, forming C5b67, which associates with an adjacent membrane. C5b67 then binds to C8 and multiple C9 ...

X-box binding protein 1. increases splicing. ISO. aloe emodin results in increased splicing of XBP1 mRNA. CTD. PMID:22210228. ... tumor protein p53. increases expression. ISO. aloe emodin results in increased expression of TP53 protein. CTD. PMID:19928967. ... fatty acid binding protein 4. multiple interactions. ISO. aloe emodin inhibits the reaction [1-Methyl-3-isobutylxanthine ... CYP3A4 protein results in increased chemical synthesis of aloe emodin. [CYP3A4 protein results in increased metabolism of ...

i qPCR analysis of liver mRNA levels of gt/gt mice relative to wt, studied relative to TATA-box-binding protein mRNA. a, b, e-i ... i qPCR analysis of liver mRNA levels of gt/gt mice relative to wt, studied relative to TATA-box-binding protein mRNA. j Western ... CCAAT-enhancer-binding protein alpha; CHREBP, carbohydrate-responsive element-binding protein; DGAT1, diacylglycerol o- ... studied relative to TATA-box-binding protein mRNA. Data are means ± SEM. *p , 0.05, **p , 0.01, ***p , 0.001. The p value for d ...

HMG-box [47096] (10 proteins). *. Protein Nucleolar transcription factor 1 (Upstream binding factor 1, UBF-1) [68982] (2 ... Upstream binding factor 1, UBF-1) {Mouse (Mus musculus) [TaxId: 10090]} ... Other proteins in same PDB: d1v64a2, d1v64a3. Structural genomics target, HMG box 3. ... Contains 6 HMG-box domains. *. Species Mouse (Mus musculus) [TaxId:10090] [109764] (3 PDB entries). Uniprot P25976 388-383, 392 ...

Assessing the conformational changes of pb5, the receptor-binding protein of phage T5, upon binding to its Escherichia coli ... The structure of the box C/D enzyme reveals regulation of RNA methylation.. Nature (2013) 502(7472) : 519-523 ... The protein that interacts with the anti-apoptotic protein survivin and the oncogenic viral protein HBx.. Journal of Molecular ... Chemical shift backbone assignments of TAP-N, the 31 kDa cargo-binding region of the protein TAP.. Journal of Biomolecular NMR ...

X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5;. ... X-box-binding protein 1; XBP-1; Tax-responsive element-binding protein 5;. ... Category: Identical to known human protein(Category I). Identical to known human protein (P17861) [Identity/coverage = 100.0%/ ...

It specifically targets X-box-binding protein 1 (XBP1) mRNA, from which a 26 nt intron is spliced. This allows a complete ... the UPR leads to a decrease in the protein folding load by causing a reduction in the general level of protein translation, and ... which leads to the activation of unfolded protein response (UPR) through three transmembrane protein sensors located in the ER ... Creation and characterization of a luciferase reporter cell line for studying the regulation of IRE1-mediated Unfolded Protein ...

C57BL/6 mice were immunised with human interphotoreceptor retinoid binding protein peptide 1-20 (IRBP1-20). ATRA was ... Intracellular expression of transcription factor forkhead box P3 (Foxp3) and interleukin (IL)-17 in the activated CD4+ T cells ... 1Department of Ophthalmology, Kyorin University School of Medicine, Tokyo, Japan. *. 2Division of Radioisotope Research, Kyorin ... In vivo-primed draining lymph node cells from vehicle-treated or ATRA-treated mice were stimulated with IRBP1-20 and the ...