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*  Active 人 Wingless-Type MMTV Integration Site Family, Member 1 (WNT1) 蛋白, Recombinant | ABIN413893
Mature human Wnt-1 is a glycosylated protein containing 343 amino acid residues. Recombinant human Wnt-1 is a 38.4 kDa, non- ... Wnt-1 is a secreted protein that signals through the Frizzled family of cell surface receptors and is required for normal ... Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. ... of the intraCellular signaling protein, β-catenine. Wnt signaling induces and maintains the transformed phenotype and, in ...
https://www.antibodies-online.cn/protein/413893/Wingless-Type+MMTV+Integration+Site+Family,+Member+1+WNT1+Active+protein/
*  Osteoporosis-Pseudoglioma Syndrome: Three Novel Mutations in the LRP5 Gene and Response to Bisphosphonate Treatment - Abstract ...
OPPG is caused by homozygous mutations in the low-density lipoprotein receptor-related protein 5 (LRP5) gene. We present three ... a Wnt co-receptor. J Cell Biol 2002;157:303-314. External Resources * Crossref (DOI) ... Gong Y, Slee RB, Fukai N, Warman ML, Osteoporosis-Pseudoglioma Syndrome Collaborative Group: LDL receptor-related protein 5 ( ... LDL receptor-related protein 5 (LRP5) mutations and osteoporosis, impaired glucose metabolism and hypercholesterolaemia. Clin ...
https://www.karger.com/Article/Abstract/336193
*  Protocol for the purification of Wnt proteins | The Wnt Homepage
Wg protein can be tested for the stabilization of the Armadillo protein [Van Leeuwen, 1994 ) and Wnt-1 protein can induce ... Note: Several Wnt proteins are being sold by R&D systems.. New as of 2016: Mihara et al have described that adding the protein ... Wnt elution from Blue Sepharose is done in a single step from 150mM to 1.5M KCl; approximately half of the Wnt protein elutes ... The Drosophila Wg [Van Leeuwen, 1994 ] and DWnt-3 [Fradkin, 1995] proteins and the mouse Wnt-1 protein [Bradley, 1995] have ...
https://web.stanford.edu/group/nusselab/cgi-bin/wnt/purification
*  Protein Wnt-2 (A4D7S0) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ...
http://www.ebi.ac.uk/interpro/protein/A4D7S0
*  Helping Wingless take flight: how WNT proteins are secreted. - Zurich Open Repository and Archive
How functional WNT proteins are made and how their secretion is regulated is becoming a focal point for the WNT-signalling ... How functional WNT proteins are made and how their secretion is regulated is becoming a focal point for the WNT-signalling ... Hausmann, G; Bänziger, C; Basler, K (2007). Helping Wingless take flight: how WNT proteins are secreted. Nature Reviews. ... Recently, lipoprotein particles, WNT lipid modifications, the conserved transmembrane protein Wntless (WLS; also known as EVI ...
https://www.zora.uzh.ch/id/eprint/1010/
*  RePub, Erasmus University Repository: Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem...
Wnt signalling proteins are essential for culture of human organ stem cells in organoids, but most Wnt protein formulations are ... Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. Publication. Publication. Nature ... By stabilizing the Wnt3a protein using phospholipids and cholesterol as carriers, we address both problems: Wnt activity ... Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. Nature Communications, 8. doi: ...
https://repub.eur.nl/pub/98541
*  wnt11 - Protein Wnt-11 precursor - Danio rerio (Zebrafish) - wnt11 gene & protein
Protein-protein interaction databases. STRING: functional protein association networks. More...STRINGi. 7955.ENSDARP00000012233 ... Protein-protein interaction databases. STRING: functional protein association networks. More...STRINGi. 7955.ENSDARP00000012233 ... Protein. Similar proteins. Organisms. Length. Cluster ID. Cluster name. Size. O73864. UPI0007B97366. B8JM95. B3DH42. A0A0B5JS77 ... to allow unambiguous identification of a protein.,p>,a href='/help/protein_names' target='_top'>More...,/a>,/p>Protein namesi. ...
http://www.uniprot.org/uniprot/O73864
*  WNT5A - Protein Wnt-5a precursor - Homo sapiens (Human) - WNT5A gene & protein
In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent ... Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin ... to allow unambiguous identification of a protein.,p>,a href='/help/protein_names' target='_top'>More...,/a>,/p>Protein namesi. ... "Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/alpha-albumin.". Mihara E. ...
https://www.uniprot.org/uniprot/P41221
*  The informational content of gradients of Wnt proteins. - Semantic Scholar
This perspective focuses on members of the Wnt family. The author proposes that Wnt proteins may act as stabilizing signals for ... This perspective focuses on members of the Wnt family. The author proposes that Wnt proteins may act as stabilizing signals for ... The informational content of gradients of Wnt proteins.. *. Alfonso Martinez Arias. *. Published. 2000 in Science's STKE : ... article{Arias2000TheIC, title={The informational content of gradients of Wnt proteins.}, author={Alfonso Martinez Arias}, ...
https://www.semanticscholar.org/paper/The-informational-content-of-gradients-of-Wnt-prot-Arias/da2349c98eaea3d6a4da08d1bebe808214e8402e
*  Literature: Wnt-11 protein (IPR026536) | InterPro | EMBL-EBI
We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their ... InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites ... Wnt-11 protein (IPR026536). References used in this entry. The following publications were referred to in the abstract: * Wnt ... Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis.. Pandur P, Lasche M, Eisenberg LM, ...
http://www.ebi.ac.uk/interpro/entry/IPR026536/literature
*  Wnt Proteins | CTD
Wingless Type Proteins , Wnt Factors Definition Wnt proteins are a large family of secreted glycoproteins that play essential ... The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.. Curation Status No associations ... They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. ...
http://ctdbase.org/detail.go?type=chem&acc=D051153
*  'Wnt' Proteins Promote Tumour Growth in Bone -- MEDICA - World Forum for...
New research by U-M scientists shows that prostate cancer manipulates an important group of signalling proteins called Wnts to ... which is known to inhibit Wnt activity. They discovered that the amounts of Wnt and DKK-1 protein present in human prostate ... In the first phase of their research, the scientists measured the amount of Wnt protein in cells from normal human prostate ... "When we altered the cells to increase the amount of active DKK-1, it blocked Wnt's signal, changing prostate cancer cells from ...
https://www.medica-tradefair.com/cgi-bin/md_medica/lib/pub/tt.cgi/%22Wnt%22_Proteins_Promote_Tumour_Growth_in_Bone.html?oid=16418&lang=2&ticket=g_u_e_s_t
*  CellNetworks - Active Wnt proteins are secreted on exosomes
Wnt signalling has important roles during development and in many diseases. As morphogens, hydrophobic Wnt proteins exert their ... Homepage »Research Network »Publications »2012 »Active Wnt proteins are secreted on exosomes ... Recent studies have identified several factors that are required for the secretion of Wnt proteins; however, how Wnts travel in ... Our study demonstrates an evolutionarily conserved functional role of extracellular vesicular transport of Wnt proteins. ...
http://www.cellnetworks.uni-hd.de/385284/Active_Wnt_proteins_are_secreted_on_exosomes
*  Nusse Lab studies complexity of Wnt signal protein as 2019 conference approaches - The Stanford Daily
Nusse is interested in how the cell cycle affects Wnt signals and the specifics of how Wnt protein receptors function. Although ... Tags:19822019AnbarchianbiologyconferenceEllengeneGordonHaroldlabNusseproteinresearchRimRoelandTeniVarmuswntwnt1 ... Nusse Lab studies complexity of Wnt signal protein as 2019 conference approaches. by Jessica Jen - October 1, 2018. October 1, ... On a day-to-day basis, she takes care of cell cultures and images them to look for proteins involved in the Wnt pathway. ...
https://www.stanforddaily.com/2018/10/01/nusse-lab-studies-complexity-of-wnt-signal-protein-as-2019-conference-approaches/
*  Protein Wnt-10b
Member of the Wnt ligand gene family that encodes for secreted proteins, which activate the Wnt signaling cascade. Specifically ... The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been ... This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a ... This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family ...
https://pharos.nih.gov/idg/targets/WNT10B
*  Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development | Development
Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development. Nathan J. Palpant, Lil Pabon, ... Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development Message Subject (Your Name) has ... Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development. Nathan J. Palpant, Lil Pabon, ... Transmembrane protein 88: a Wnt regulatory protein that specifies cardiomyocyte development. Nathan J. Palpant, Lil Pabon, ...
http://dev.biologists.org/content/early/2013/08/07/dev.094789
*  WNT Signaling Protein May Play Key Role in Glaucoma - Natural Eye Care Blog: News & Research on Vision
WNT Signaling Protein May Play Key Role in Glaucoma. A new study demonstrates that increased protein expression (DNA to RNA to ... The lab eyes also had less expression of another protein, WNT, involved in the signaling process ... polypeptide to protein) of the protein sFRP-1 may be a causal factor for higher IOP in patients wiht glacuoma. This protein ... They were able to reverse and thus resolve the problem in the lab mice by addressing the issue of WNT signaling. ...
https://www.naturaleyecare.com/blog/wnt-signaling-protein-may-play-key-role-in-glaucoma/
*  Protein Wnt-8b
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been ... This gene is a member of the WNT gene family. It encodes a protein which shows 95%, 86% and 71% amino acid identity to the ... mouse, zebrafish and Xenopus Wnt8B proteins, respectively. The expression patterns of the human and mouse genes appear ...
https://pharos.nih.gov/idg/targets/WNT8B
*  Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells. - hepaton
Wnt signalling proteins are essential for culture of human organ stem cells in organoids, but most Wnt protein formulations are ... Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells.. Tüysüz N, van Bloois L, van den ... By stabilizing the Wnt3a protein using phospholipids and cholesterol as carriers, we address both problems: Wnt activity ... Here we show that purified Wnt3a protein is ineffective because it rapidly loses activity in culture media due to its ...
http://hepaton.com/634/lipid-mediated-wnt-protein-stabilization-enables-serum-free-culture-of-human-organ-stem-cells/
*  iHOP - Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector...
iHOP provides the network of genes and proteins as a natural way of accessing the millions of abstracts in PubMed. By employing ... genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed becomes bound together into one ...
http://www.ihop-net.org/UniPub/iHOP/pm/9801016.html?nr=10&pmid=12446687
*  Phosphorylation of Dishevelled by Protein Kinase RIPK4 Regulates Wnt Signaling | Science
At the molecular level, RIPK4 interacted with the Wnt co-receptor LRP6 and the Wnt signaling adaptor protein DVL2 and promoted ... describe the mechanism of action of a protein found in a screen for proteins that influence Wnt signaling. DDX3, a DEAD-box RNA ... The protein kinase RIPK4 is identified as a component of the Wnt signaling pathway. [Also see Perspective by Berndt and Moon] ... The protein kinase RIPK4 is identified as a component of the Wnt signaling pathway. [Also see Perspective by Berndt and Moon] ...
http://science.sciencemag.org/content/339/6126/1441
*  Gentaur Molecular :Prospecbio \ Mouse Anti Human Protein Wnt-3a WNT3A \ ant-431
Mouse Anti Human Protein Wnt-3a WNT3A \ ant-431 for more molecular products just contact us ... WP1098: Wnt Signaling Pathway. WP1129: Wnt Signaling Pathway and Pluripotency. WP1135: Wnt Signaling Pathway. WP1165: G Protein ... Index / Prospecbio / Mouse Anti Human Protein Wnt-3a WNT3A / Product Detail : ant-431 Mouse Anti Human Protein Wnt-3a WNT3A. ... We have also other products like : Mouse Anti Human Protein Wnt-3a WNT3A. Related products : Mouse Anti Human Protein Wnt-3a ...
http://www.antibody-antibodies.com/product_det.php?id=2793511&supplier=search&name=Mouse%20Anti%20Human%20Protein%20Wnt_3a%20WNT3A
*  "Insights into Chibby's structure and protein interactions in Wnt signaling" by Ryan C Killoran
The partially disordered protein Chibby (Cby) is a conserved nuclear protein that acts as an antagonist in the Wnt/b-catenin ... this thesis demonstrates how Cby's structural elements collectively mediate protein-protein interactions in the Wnt signaling ... Mutations to Wnt signaling components can cause dysregulation of the pathway, leading to various human diseases such as cancer ... Moreover, upon phosphorylation on serine 20 by the kinase Akt, Cby forms a complex with the protein 14-3-3 to facilitate the ...
https://ir.lib.uwo.ca/etd/3955/
*  The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway...
The Wnt pathway has multiple actions in the cascade of events triggered by Aβ, and drugs that rescue Wnt activity may be ... The marijuana component cannabidiol inhibits β-amyloid-induced tau protein hyperphosphorylation through Wnt/β-catenin pathway ... Protein kinase C inhibits amyloid beta peptide neurotoxicity by acting on members of the Wnt pathway. FASEB J 16(14):1982-1984 ... A role for Wnt signaling pathway. Neurobiol Dis 17(2):337-348PubMedCrossRefGoogle Scholar ...
https://link.springer.com/article/10.1007%2Fs00109-005-0025-1
*  Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. | Sigma-Aldrich
Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation.. [Juan Liang, Yu Fu, Cristina-Maria ... Upon Wnt stimulation, cognate coreceptors LRP5 and LRP6 ([LRP5/6] low-density lipoprotein receptor-related proteins 5 and 6) ... Thus, our results identified TMEM198 as a membrane scaffold protein that promotes LRP6 phosphorylation and Wnt signaling ... Here, we report that transmembrane protein 198 (TMEM198), a previously uncharacterized seven-transmembrane protein, is able to ...
https://www.sigmaaldrich.com/catalog/papers/21536646