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*  Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection
... ... "Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection." Nature ... We demonstrate that Nod2−/− and Ripk2−/− mice are hypersusceptible to influenza A virus infection. Ripk2−/− cells displayed ... Accordingly, Ulk1−/− cells displayed enhanced mitochondrial superoxide production and caspase-1 activation. These results ...
https://dash.harvard.edu/handle/1/11879094
*  NIH Guide: REGULATION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) ACTIVATION IN THE LUNG
Several factors, both intrinsic to the virus and external, have been proposed to influence the activation of HIV in the lung. ... Full Text HL-96-008 REGULATION OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) ACTIVATION IN THE LUNG NIH GUIDE, Volume 25, Number 4, ... This Request for Applications (RFA), Regulation of Human Immunodeficiency Virus (HIV) Activation in the Lung, is related to the ... o examine genetic factors within the host lung cells that control activation of virus; o elucidate specific pathways whereby co ...
https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-96-008.html
*  Dengue Virus Induces NK Cell Activation through TRAIL Expression during Infection
... Mariana Gandini,1,2 Fabienne Petitinga-Paiva ... R. Hamel, O. Dejarnac, S. Wichit et al., "Biology of Zika virus infection in human skin cells," Journal of Virology, vol. 89, ... Y. T. Tsai, S. Y. Chang, C. N. Lee, and C. L. Kao, "Human TLR3 recognizes dengue virus and modulates viral replication in vitro ... R. S. Lanciotti, C. H. Calisher, D. J. Gubler, G. J. Chang, and A. V. Vorndam, "Rapid detection and typing of dengue viruses ...
https://www.hindawi.com/journals/mi/2017/5649214/ref/
*  Activation of host autophagy by virus
Some viruses such as poliovirus, use the autophagic pathway as a nonlytic mechanism for viral release. ... Viral protein involved in the activation of host autophagy. Autophagy is a major intracellular pathway in the delivery of ... Although autophagy is clearly important for antiviral immune response, it can also be activated by viruses and serves as ...
https://www.uniprot.org/keywords/KW-1072
*  Involvement of unfolded protein response, p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus...
... p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus-mediated JNK activation.. [Yazhen Huo, Lihong ... previous study has shown that activation of JNK plays a critical role in Porcine reproductive and respiratory syndrome virus ( ... In this follow-up study, we further investigated the mechanisms involved in modulation of PRRSV-mediated JNK activation and ... was induced in response to PRRSV infection which in turn triggered JNK activation and apoptosis. We also found that p53 and Akt ...
https://www.sigmaaldrich.com/catalog/papers/23850458
*  Activation of anti-hepatitis C virus responses via Toll-like receptor 7 | PNAS
Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Jongdae Lee, Christina C. N. Wu, Ki Jeong Lee, Tsung- ... Activation of anti-hepatitis C virus responses via Toll-like receptor 7 ... Activation of anti-hepatitis C virus responses via Toll-like receptor 7 ... Activation of anti-hepatitis C virus responses via Toll-like receptor 7 ...
https://www.pnas.org/content/103/6/1828?ijkey=73b13d5858a2aaa461ff36a43b79a2982c9c8ebe&keytype2=tf_ipsecsha
*  Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo | JEM
Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo. Kazuhiro Kakimi, Luca G. Guidotti, Yasuhiko ... 2000) Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines. J. Virol. ... Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo ... Indirect mechanisms could include activation of NKT cells by virus-induced cytokines (6)(22). Additional studies will be needed ...
http://jem.rupress.org/content/192/7/921?ijkey=0ab85bc6726550630c37db5933f56a6a723bc8da&keytype2=tf_ipsecsha
*  Uklonite virus Facebook Activation Pages Service (Besplatne instrukcija)
Ključne osobine prevarantskog virusa Facebook Activation Pages Service: Nedavno su korisnici Facebooka suočili su se s novom ... Kako ukloniti virus Facebook Activation Pages Service?. Kao što smo već spomenuli, virus Facebook Activation Pages Service ... Facebook Activation Pages Service virus. Kako ukloniti? (Vodič za deinstalaciju). od Lucia Danes - - 2016-11-30. , Tip: Malware ... Virus Facebook Activation Pages Service je nepredvidljiv i može se skrivati bilo gdje, pa vas molimo da budete na oprezu! ...
http://virusi.hr/facebook-activation-pages-service-virus/
*  Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal...
The virus-induced Raf/MEK/ERK (MAPK) signal cascade is crucial for efficient virus replication. Blockade of this pathway ... induced greater ERK activation, resulting in increased nuclear export of the viral genome and higr virus titers. We conclude ... Infection with H3N2 virus, which replicates efficiently, resulted in higher HA expression and its accumulation on the cell ... We studied the induction of MAPK signal cascade by two seasonal human influenza A viruses A/HK/218449/06 (H3N2) and A/HK/218847 ...
https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-4-134
*  IRF-3 Activation by Sendai Virus Infection Is Required for Cellular Apoptosis and Avoidance of Persistence | Journal of Virology
... mumps virus, respiratory syncytial virus, parainfluenza viruses (PIVs), and Newcastle disease virus (18). Sendai virus (SeV) is ... Activation of PI3K is not required for activation of the JNK and TBK1 pathways. A. HT1080 cells were infected with Sendai virus ... Although virus infection activated PI3 kinase, as indicated by AKT activation, its blockage did not inhibit JNK activation or ... The hPIV3 virus was propagated in CV1 cells (22). Virus infections were carried out as described for Sendai virus with a ...
https://jvi.asm.org/content/82/7/3500
*  AID 288762 - Inhibition of TPA-induced Epstein-Barr virus early antigen activation assessed as EBV-EA induction in Raji cells...
Inhibition of TPA-induced Epstein-Barr virus early antigen activation assessed as EBV-EA induction in Raji cells at 3.2 nM ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/288762
*  Viruses | Free Full-Text | PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells
These findings suggest that IPNV uses PKR activation to promote virus replication in infected cells. ... We investigated the involvement of PKR during infectious pancreatic necrosis virus (IPNV) infection using a custom-made rabbit ... PKR inhibitor pre-treatment resulted in decreased virus titers, extra- and intracellularly, concomitant with reduction of cells ... PKR Activation Favors Infectious Pancreatic Necrosis Virus Replication in Infected Cells. Viruses 2016, 8, 173. ...
http://www.mdpi.com/1999-4915/8/6/173
*  Toll-like receptor-mediated activation of neutrophils by influenza A virus | Blood Journal
... and virus treated at 100°C (Figure 3). We found that virus treated at 56°C behaved similarly to active virus in that both virus ... Toll-like receptor-mediated activation of neutrophils by influenza A virus. Jennifer P. Wang, Glennice N. Bowen, Carolyn Padden ... Toll-like receptor-mediated activation of neutrophils by influenza A virus. Jennifer P. Wang, Glennice N. Bowen, Carolyn Padden ... Toll-like receptor-mediated activation of neutrophils by influenza A virus. Jennifer P. Wang, Glennice N. Bowen, Carolyn Padden ...
http://www.bloodjournal.org/content/112/5/2028?ijkey=0989307bd8fe39d8761fcbb2202a147b2c9c19c0&keytype2=tf_ipsecsha&sso-checked=true
*  Activation of Hepatitis B Virus (HBV) in Hepatitis B Surface Antigen (HBsAg) - Negative But Hepatitis B Core Antibody (Anti-HBc...
Virus Diseases. Enterovirus Infections. Picornaviridae Infections. RNA Virus Infections. Hepadnaviridae Infections. DNA Virus ... Activation of Hepatitis B Virus (HBV) in Hepatitis B Surface Antigen (HBsAg) - Negative But Hepatitis B Core Antibody (Anti-HBc ... Activation of HBV Under Immunosuppression in HBsAg-negative But Anti-HBc-positive Patients With Hematological Malignancies. ... have latent hepatitis B virus (HBV) infection in their liver tissue. Cytotoxic chemotherapy and hematopoietic stem cell ...
https://clinicaltrials.gov/show/NCT00881036
*  AID 1283845 - Inhibition of TPA-induced Epstein-Barr virus early antigen activation infected in human Raji cells assessed as...
Inhibition of TPA-induced Epstein-Barr virus early antigen activation infected in human Raji cells assessed as relative ratio ... of EBV-EA activation at 1000 mol ratio/TPA after 48 hrs by immunofluorescence assay (Rvb = 100%). ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/1283845
*  Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation. | Sigma-Aldrich
Influenza A virus nucleoprotein exploits Hsp40 to inhibit PKR activation.. [Kulbhushan Sharma, Shashank Tripathi, Priya Ranjan ... However the influenza virus component responsible for PKR inhibition through P58(IPK) activation was hitherto unknown. Human ... In case of influenza A virus (IAV) infection, P58(IPK) is known to dissociate from Hsp40 and inhibit PKR activation. ... Furthermore, inhibition of NP expression during influenza virus replication led to PKR activation and concomitant increase in ...
https://www.sigmaaldrich.com/catalog/papers/21698289
*  Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes. | Journal of Virology
Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes.. L Folgueira, J A ... Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes. ... Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes. ... Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes. ...
https://jvi.asm.org/content/70/1/223?ijkey=7834ff727a9e35e912d62ef4fe8c7e8681e47fd6&keytype2=tf_ipsecsha
*  Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating...
Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating ... Eukaryotic initiation factor 5A is a cellular target of the human immunodeficiency virus type 1 Rev activation domain mediating ... Furthermore, the interaction of the Rev activation domain with a cellular cofactor is essential for Rev function in vivo. Using ... trans-activation.. M Ruhl, M Himmelspach, G M Bahr, F Hammerschmid, H Jaksche, B Wolff, H Aschauer, G K Farrington, H Probst, D ...
http://jcb.rupress.org/content/123/6/1309?ijkey=b16f39edc286d4f09c275e36962004aa97ada67b&keytype2=tf_ipsecsha
*  Activation of the Hemagglutinin of Influenza Viruses | Springer for Research & Development
... and this proteolytic processing event is critical to the virus... ... Activation of the Hemagglutinin of Influenza Viruses. *Authors ... glycoprotein of influenza viruses is posttranslationally cleaved into the disulfide-linked subunits HA1 and HA2, ... Boycott R, Klenk HD, Ohuchi M. Cell tropism of influenza virus mediated by hemagglutinin activation at the stage of virus entry ... Activation of the Hemagglutinin of Influenza Viruses. In: Böttcher-Friebertshäuser E., Garten W., Klenk H. (eds) Activation of ...
https://rd.springer.com/chapter/10.1007%2F978-3-319-75474-1_1
*  Virus-induced activation of nuclear factor-kappa B (NF-and in target tissues was
... Published by sunolmolecular UnderNon-Selective ... Virus-induced activation of nuclear factor-kappa B (NF-and in target tissues was purchased from Invitrogen and was utilized at ... apoptosis in cells infected with influenza virus,66,67 herpes virus type 2,68 bovine herpesvirus 4 (BHV 4),69 adenovirus70 and ... infection of HEK293 cells as well as the discharge of TRAIL from infected cells may thus reflect virus-induced activation of NF ...
http://www.sunolmolecular.com/2018/12/10/virus-induced-activation-of-nuclear-factor-kappa-b-nf-and-in-target-tissues-was/
*  Viruses | Free Full-Text | The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation
Hepatitis A virus (HAV; a picornavirus) and Hepatitis C virus (HCV; a flavivirus) two single strand plus-sense RNA viruses, in ... This article will review recent findings regarding these two viruses and outline how exosomes are involved in their ... leading to innate immune activation and type I interferon production. ... Longatti, A. The Dual Role of Exosomes in Hepatitis A and C Virus Transmission and Viral Immune Activation. Viruses 2015, 7, ...
http://www.mdpi.com/1999-4915/7/12/6707
*  Herpes simplex virus type 1 induces simultaneous activation of Toll-like receptors 2 and 4 and expression of the endogenous...
Herpes simplex virus type 1 (HSV-1) is the most common pathogenic cause of sporadic acute encephalitis and it produces latent ... Herpes simplex virus type 1 induces simultaneous activation of Toll-like receptors 2 and 4 and expression of the endogenous ... Collins SE, Noyce RS, Mossman KL (2004) Innate cellular response to virus particle entry requires IRF3 but not virus ... Herpes simplex virus type 1 (HSV-1) is the most common pathogenic cause of sporadic acute encephalitis and it produces latent ...
https://link.springer.com/article/10.1007%2Fs00430-012-0247-0
*  Nucleopolyhedroviruses of Forest and Western Tent Caterpillars: Cross-infectivity and Evidence for Activation of Latent Virus...
5. Virus was not activated in western tent caterpillars collected over 2 years of late population decline and the first year of ... Any virus produced in the cross-infections was charac-terised to confirm true cross-infection or to ascertain whether cross- ... inoculation triggered latent virus persisting within the population. 3. The virus associated with forest tent caterpillars ( ... The cross-infectivity of the viruses in these two host species was investigated to determine whether there might be a route for ...
https://www.semanticscholar.org/paper/Nucleopolyhedroviruses-of-Forest-and-Western-Tent-JEN-YSCOR/e133974cb2e26d0d417f7095c332650a8d39afbd
*  Stap-2 negatively regulates both canonical and noncanonical nf-b activation induced by epstein-barr virus-derived latent...
Article Stap-2 negatively regulates both canonical and noncanonical nf-b activation induced by epstein-barr virus-derived ... Stap-2 negatively regulates both canonical and noncanonical nf-b activation induced by epstein-barr virus-derived latent ... were found for Stap-2 negatively regulates both canonical and noncanonical nf-b activation induced by epstein-barr virus- ... In the present study, we found that ectopic expression of STAP-2 inhibited Epstein-Barr virus (EBV) LMP1-mediated NF-B ...
https://www.environmental-expert.com/articles/stap-2-negatively-regulates-both-canonical-and-noncanonical-nf-b-activation-induced-by-epstein-barr--36531
*  CD4 T-Cell Responses in Primary HIV Infection: Interrelationship with Immune Activation and Virus Burden • Research - Institut...
CD4 T-Cell Responses in Primary HIV Infection: Interrelationship with Immune Activation and Virus Burden. ... Patients were segregated based on CD8 T-cell activation level (i.e., % HLA-DR(+)CD38(+) CD8 T-cells) at baseline (BL). Patients ... These data suggest that HIV-specific CD4 responses do not fuel systemic T-cell activation and are driven by viral replication ... Fresh peripheral blood mononuclear cells were used for measurement of ex vivo T-cell activation and of cytokine-producing CD4 T ...
https://research.pasteur.fr/en/publication/cd4-t-cell-responses-in-primary-hiv-infection-interrelationship-with-immune-activation-and-virus-burden/