Tumor Necrosis Factor-alphaReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IIInterleukin-1CytokinesLipopolysaccharidesInterleukin-6Cells, CulturedNecrosisNF-kappa BRNA, MessengerInterferon-gammaMacrophagesLymphotoxin-alphaMice, Inbred C57BLCell LineMonocytesRecombinant ProteinsSignal TransductionApoptosisInflammationMice, Inbred BALB CGene Expression RegulationTumor Necrosis FactorsAntibodies, MonoclonalArthritis, RheumatoidTransforming Growth Factor alphaInterleukin-10Gene ExpressionInterleukin-8Dose-Response Relationship, DrugTumor Necrosis Factor Decoy ReceptorsMolecular Sequence DataAntirheumatic AgentsMice, KnockoutAntigens, CDMacrophage ActivationBase SequenceSynovial MembraneDisease Models, AnimalReverse Transcriptase Polymerase Chain ReactionTime FactorsCell Line, TumorUp-RegulationLeukocytes, MononuclearInterleukin-1betaEnzyme-Linked Immunosorbent AssayTumor Cells, CulturedTransfectionMembrane GlycoproteinsNeutrophilsInflammation MediatorsEndotoxinsMacrophages, PeritonealFlow CytometryDrug SynergismCell SurvivalI-kappa B ProteinsT-LymphocytesFibroblastsBlotting, WesternDown-RegulationCell DivisionAnti-Inflammatory AgentsPentoxifyllineImmunohistochemistryPromoter Regions, GeneticEnzyme ActivationTranscription, GeneticI-kappa B KinaseTNF Receptor-Associated Factor 2Mice, Inbred C3HInterleukin-12Nitric OxideEndothelium, VascularImmunoglobulin GTranscription Factor RelALiverIntercellular Adhesion Molecule-1Granulocyte-Macrophage Colony-Stimulating FactorTumor Markers, BiologicalReceptors, Cell SurfaceKineticsPhosphorylationTumor Necrosis Factor Receptor-Associated Peptides and ProteinsLungAntigens, CD14TNF-Related Apoptosis-Inducing LigandInterleukinsSpleenShock, SepticPolymerase Chain ReactionAntibodiesp38 Mitogen-Activated Protein KinasesLymphocyte ActivationDendritic CellsMitogen-Activated Protein KinasesCaspasesEnzyme Inhibitors