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*  trpE2 protein (Synechocystis sp. PCC6803) - STRING database
Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine ( ... Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine ... Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine ... Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to ...
https://string-db.org/newstring_cgi/show_network_section.pl?identifier=1148.SYNGTS_1641
*  Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum...
Correlations were made between brain tryptophan and (1) free serum tryptophan, (2) the ratio of free serum tryptophan to the ... Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum ... Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum ... Tryptophan concentrations in rat brain. Failure to correlate with free serum tryptophan or its ratio to the sum of other serum ...
http://www.biochemj.org/content/160/3/589
*  Electroconvulsive therapy suppresses the neurotoxic branch of the kynurenine pathway in treatment-resistant depressed patients ...
Tryptophan (a), kynurenine (b), kynurenine/tryptophan ratio (c), kynurenic acid (KYNA) (d), quinolinic acid (QUIN) (e), and ... Tryptophan (a), kynurenine (b), kynurenine/tryptophan ratio (c), kynurenic acid (KYNA) (d), quinolinic acid (QUIN) (e), and ... Tryptophan metabolites and cytokines after treatment with ECT in patients with MDD. Analysis of plasma tryptophan and ... IL-1β increases expression of tryptophan 2,3-dioxygenase and stimulates tryptophan catabolism in endometrioma stromal cells. Am ...
https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-016-0517-7
*  3-hydroxyanthranilic acid | definition of 3-hydroxyanthranilic acid by Medical dictionary
A metabolite of tryptophan degradation that can serve as a precursor for the biosynthesis of NAD+. ... 2006, 3-Hydroxyanthranilic acid, one of L-tryptophan metabolites, inhibits monocyte chemoattractant protein-1 secretion and ... tryptophan, kynurenine, kynurenic acid, anthranilic acid, 3-hydroxykynurenine, xanthurenic acid, 3-hydroxyanthranilic acid, and ...
http://medical-dictionary.thefreedictionary.com/3-hydroxyanthranilic+acid
*  Control of actinomycin D biosynthesis in Streptomyces parvullus: regulation of tryptophan oxygenase activity. - Semantic Scholar
Of these, l-glutamate and l-aspartate had the most dramatic effect on tryptophan oxygenase and beta-galactosidase (beta-d- ... The addition of 10 mM l-glutamate at this stage completely abolished actinomycin D production as well as tryptophan oxygenase ... The transfer of cells to this artificial preincubation medium resulted in the appearance of tryptophan oxygenase as early as 19 ... The results of these studies suggest that the increase in tryptophan oxygenase activity before the onset of actinomycin D ...
https://www.semanticscholar.org/paper/Control-of-actinomycin-D-biosynthesis-in-Streptomy-Foster-Katz/983c6a0c304fe80d61e1a97f99474d062768c291
*  Frontiers | Vasorelaxing Action of the Kynurenine Metabolite, Xanthurenic Acid: The Missing Link in Endotoxin-Induced...
The kynurenine pathway of tryptophan metabolism is activated by pro-inflammatory cytokines. L-kynurenine, an upstream ... The kynurenine pathway of tryptophan metabolism is activated by pro-inflammatory cytokines. L-kynurenine, an upstream ... Tryptophan is metabolized by IDO or tryptophan 2,3-dioxygenase (TDO) into formylkynurenine, which is spontaneously converted ... 2011). Tryptophan metabolism to kynurenine is a potential novel contributor to hypotension in human sepsis. Crit. Care Med. 39 ...
https://www.frontiersin.org/articles/10.3389/fphar.2017.00214/full
*  Tryptophan synthase - Wikipedia
Tryptophan synthase or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan ... Tryptophan is one of the twenty standard amino acids and one of nine essential amino acids for humans. As such, tryptophan is a ... The active sites of tryptophan synthase are allosterically coupled. Subunits: Tryptophan synthase typically exists as an α-ββ-α ... generating the corresponding tryptophan analogues. As humans do not have tryptophan synthase, this enzyme has been explored as ...
https://en.wikipedia.org/wiki/Tryptophan_synthase
*  Peripheral serotonin 1B receptor transcription predicts the effect of acute tryptophan depletion on risky decision-making - PSY
... and tryptophan hydroxylase 1. Results: Acute tryptophan depletion did not significantly influence participants' sensitivity to ... In 21 participants, mRNA from 9 serotonin system genes was measured in whole blood prior to acute tryptophan depletion: 5-HT1B ... Conclusions: These results suggest that the 5-HT1B receptor may modulate the effects of acute tryptophan depletion on risky ... predicted the effect of acute tryptophan depletion on decision-making. Participants performed a task in which they chose ...
https://www.psy.ox.ac.uk/publications/681379
*  Chapter 7: Role of the kynurenine pathway in immune- mediated infl ammation - Nuffield Department of Orthopaedics, Rheumatology...
... of the kinetics of expression of kynurenine pathway enzymes in animal models also pointed to a potential role for tryptophan ... Indoleamine 2,3-dioxygenase (IDO) plays a key role in immune homeostasis via depletion of tryptophan and accumulation of ... Indoleamine 2,3-dioxygenase (IDO) plays a key role in immune homeostasis via depletion of tryptophan and accumulation of ... of the kinetics of expression of kynurenine pathway enzymes in animal models also pointed to a potential role for tryptophan ...
https://www.ndorms.ox.ac.uk/publications/604845
*  Tryptophan hydroxylase - Wikipedia
The activity of tryptophan hydroxylase (i.e. the rate at which it converts L-tryptophan into the serotonin precursor L-5- ... Tryptophan Hydroxylase at the US National Library of Medicine Medical Subject Headings (MeSH) See also tryptophan hydroxylase ... The pathway for the synthesis of serotonin from tryptophan Metabolic pathway from tryptophan to serotonin Molecular and ... Tryptophan hydroxylase (TPH) is an enzyme (EC 1.14.16.4) involved in the synthesis of the neurotransmitter serotonin. Tyrosine ...
https://en.wikipedia.org/wiki/Tryptophan_hydroxylase
*  TPH1 - Wikipedia
Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the TPH1 gene. TPH1 was ... Tryptophan hydroxylases catalyze the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5-HTP), which is ... TPH1 tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)". Finocchiaro LM, Arzt ES, Fernández-Castelo S, Criscuolo M, ... 2002). "Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's ...
https://en.wikipedia.org/wiki/TPH1
*  Tryptophan - Wikipedia
So high levels of tryptophan prevent tryptophan synthesis through a negative feedback loop, and when the cell's tryptophan ... Hopkins recovered tryptophan from hydrolysed casein, recovering 4-8 g of tryptophan from 600 g of crude casein. As an essential ... Tryptophan is also a precursor to the neurotransmitter serotonin and the hormone melatonin. Like other amino acids, tryptophan ... By this reaction, tryptophan gives rise to tryptophol. Tryptophan affects brain serotonin synthesis when given orally in a ...
https://en.wikipedia.org/wiki/Tryptophan
*  Tryptophan?
... Peter Hood Peter at brentano.demon.co.uk Sat Aug 26 16:51:51 EST 1995 *Previous message: Tryptophan? ... How can one legally obtain tryptophan? By prescription (see other threads) or by eating a naturally tryptophan enriched diet ...
http://www.bio.net/bionet/mm/neur-sci/1995-August/020091.html
*  Tryptophan transaminase - Wikipedia
L-tryptophan aminotransferase, and L-tryptophan transaminase. This enzyme participates in tryptophan metabolism. It employs one ... In enzymology, a tryptophan transaminase (EC 2.6.1.27) is an enzyme that catalyzes the chemical reaction L-tryptophan + 2- ... The systematic name of this enzyme class is L-tryptophan:2-oxoglutarate aminotransferase. Other names in common use include L- ... O'Neil SR, DeMoss RD (1968). "Tryptophan transaminase from Clostridium sporogenes". Arch. Biochem. Biophys. 127 (1): 361-9. doi ...
https://en.wikipedia.org/wiki/Tryptophan_transaminase
*  Tryptophan 7-halogenase - Wikipedia
Other flavin-dependent tryptophan halogenases include tryptophan 5-halogenase and tryptophan 6-halogenase. Tryptophan 7- ... Tryptophan 7-halogenase (EC 1.14.19.9, PrnA, RebH) is an enzyme with systematic name L-tryptophan:FADH2 oxidoreductase (7- ... Tryptophan is bound by a number of interactions: other aromatic amino acid residues such as tryptophan, phenylalanine, and ... 7-chloro-L-tryptophan + FAD + 2 H2O The enzyme can use bromide ions (Br−) in place of chloride (Cl−). Tryptophan 7-halogenase ...
https://en.wikipedia.org/wiki/Tryptophan_7-halogenase
*  Tryptophan repressor - Wikipedia
... proteins which make more tryptophan. When the cellular levels of tryptophan decline, the tryptophan molecules on the repressor ... The (tryptophan) repressor is a 25 kD protein homodimer which regulates transcription of the tryptophan biosynthetic pathway in ... When the amino acid tryptophan is in plentiful supply in the cell, trpR binds 2 molecules of tryptophan, which alters its ... The trp operon is active only when cellular tryptophan is scarce. If there isn't enough tryptophan, the repressor protein ...
https://en.wikipedia.org/wiki/Tryptophan_repressor
*  Tryptophan dehydrogenase - Wikipedia
In enzymology, a tryptophan dehydrogenase (EC 1.4.1.19) is an enzyme that catalyzes the chemical reaction L-tryptophan + NAD(P ... Vackova K, Mehta A, Kutacek M (1985). "Tryptophan aminotransferase and tryptophan dehydrogenase - activities in some cell ... L-tryptophan dehydrogenase, L-tryptophan dehydrogenase, L-Trp-dehydrogenase, and TDH. This enzyme has at least one effector, ... The systematic name of this enzyme class is L-tryptophan:NAD(P)+ oxidoreductase (deaminating). Other names in common use ...
https://en.wikipedia.org/wiki/Tryptophan_dehydrogenase
*  Tryptophan tryptophylquinone - Wikipedia
Tryptophan tryptophylquinone(TTQ) is an enzyme cofactor, generated by posttranslational modification of amino acids within the ... Amicyanin Davidson VL, Liu A: Uncovering novel biochemistry in the mechanism of tryptophan tryptophylquinone cofactor ...
https://en.wikipedia.org/wiki/Tryptophan_tryptophylquinone
*  Tryptophan dimethylallyltransferase - Wikipedia
L-tryptophan Thus, the two substrates of this enzyme are dimethylallyl diphosphate and L-tryptophan, whereas its two products ... tryptophan dimethylallyl transferase, DMAT synthetase, and 4-(gamma,gamma-dimethylallyl)tryptophan synthase. Lee SL, Floss HG, ... In enzymology, a tryptophan dimethylallyltransferase (EC 2.5.1.34) is an enzyme that catalyzes the chemical reaction ... The systematic name of this enzyme class is dimethylallyl-diphosphate:L-tryptophan dimethylallyltransferase. Other names in ...
https://en.wikipedia.org/wiki/Tryptophan_dimethylallyltransferase
*  L-tryptophan (CHEBI:16828)
... is enantiomer of D-tryptophan (CHEBI:16296) L-tryptophan (CHEBI:16828) is tautomer of L-tryptophan ... L-tryptophan (CHEBI:16828) is a tryptophan (CHEBI:27897) L-tryptophan (CHEBI:16828) is conjugate acid of L-tryptophanate (CHEBI ... L-tryptophan (CHEBI:16828) has role plant metabolite (CHEBI:76924) L-tryptophan (CHEBI:16828) is a L-α-amino acid (CHEBI:15705 ... L-tryptophan (CHEBI:16828) has role Escherichia coli metabolite (CHEBI:76971) L-tryptophan (CHEBI:16828) has role Saccharomyces ...
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:21407
*  Erowid Tryptophan Vault
Information about Tryptophan including basics, effects, dosage, history, legal status, photos, research, media coverage, and ... L-Tryptophan is present in a wide range of foods including beans, nuts, milk, and poultry. L-Tryptophan is a precursor to 5-HTP ... L-Tryptophan is an essential amino acid, meaning the human body does not produce it naturally, but is required for the body's ... L-Tryptophan was banned by the FDA in the 1990s because of contamination in the production process, but was re-released onto ...
https://www.erowid.org/smarts/tryptophan/tryptophan.shtml
*  Tryptophan 2-monooxygenase - Wikipedia
In enzymology, a tryptophan 2-monooxygenase (EC 1.13.12.3) is an enzyme that catalyzes the chemical reaction L-tryptophan + O2 ... I. The conversion of L-tryptophan to indole-3-acetamide by an enzyme system from Pseudomonas savastanoi". J. Biol. Chem. 241 ( ... the two substrates of this enzyme are L-tryptophan and O2, and its 3 products are (indol-3-yl)acetamide, CO2, and H2O. This ... The systematic name of this enzyme class is L-tryptophan:oxygen 2-oxidoreductase (decarboxylating). This enzyme participates in ...
https://en.wikipedia.org/wiki/Tryptophan_2-monooxygenase
*  Tryptophan operon leader - Wikipedia
The Tryptophan operon leader is an RNA element found at the 5' of some bacterial tryptophan operons. The leader sequence can ... Tryptophan RNA-binding attenuator protein inhibitory protein (Anti-TRAP protein or AT) is a short protein encoded by the rtpA ... TRAP protein forms an oligomer of 11 subunits, in the presence of tryptophan this binds to section of RNA containing 11 (G/U)AG ... The leader also codes for very short peptide sequence that is rich in tryptophan. The terminator structure is recognised as a ...
https://en.wikipedia.org/wiki/Tryptophan_operon_leader
*  Nanosensor Detection of an Immunoregulatory Tryptophan Influx/Kynurenine Efflux Cycle
Genetically encoded FRET nanosensors were developed to measure cytosolic tryptophan steady-state levels and flux in real time. ... Tryptophan Is the Subject Area "Tryptophan" applicable to this article? Yes. No. ...
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0050257
*  L-Tryptophan - Fromm Family Foods
L-Tryptophan. Tryptophan is an essential amino acid, therefore required for a complete and balanced diet. It is used in protein ...
https://frommfamily.com/ingredients/l-tryptophan/