Immunizing with mouse trophoblast to obtain mouse-human cross-reacting antibodies against normal and neoplastic human...Immunizing with mouse trophoblast to obtain mouse-human cross-reacting antibodies against normal and neoplastic human...

... which implies that mouse trophoblast cells can be used as immunogen for producing antibodies against human trophoblast. Among ... Immunizing with mouse trophoblast to obtain mouse-human cross-reacting antibodies against normal and neoplastic human ... That panel includes a trophoblast specific antibody with capacity to differ between invasive and noninvasive molar tissues, and ... Monoclonal antibodies raised against living, early invasive mouse trophoblast cells were screened on paraffin sections from ...
more infohttp://uu.diva-portal.org/smash/record.jsf?pid=diva2:894403

Hydatidiform Mole Research Paper - 1072 WordsHydatidiform Mole Research Paper - 1072 Words

Abnormal trophoblast cells must be identified because they are associated with choriocarcinoma, a rapidly metastasizing ... The placenta is made of millions of cells called trophoblasts. These two parts normally develop together, in parallel, the end ... a malignant tumor of trophoblast cells - than do partial moles. The etymology is derived from hydatisia (Greek a drop of water ...
more infohttp://www.studymode.com/essays/Hydatidiform-Mole-1095180.html

Testosterone production with hydatidiform moles - in vitro and in vivo studies | ScholarBank@NUSTestosterone production with hydatidiform moles - in vitro and in vivo studies | [email protected]

... testosterone level in molar pregnancy is mainly due to the conversion of dehydroepiandrosterone in the molar trophoblast. ... indicating that 17-hydroxysteroid dehydrogenase and 3β-hydroxysteroid dehydrogenase are present in molar trophoblast. A 50 mg ...
more infohttp://scholarbank.nus.edu.sg/handle/10635/133736

Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic...Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic...

For instance, in partial and complete moles HtrA1 is weakly expressed in the trophoblast. Moreover, absence of immunoreaction ... For instance, in partial and complete moles HtrA1 is weakly expressed in the trophoblast. Moreover, absence of immunoreaction ...
more infohttps://usiena-air.unisi.it/handle/11365/8759

Trophoblast Invasion and Endometrial Receptivity | SpringerLinkTrophoblast Invasion and Endometrial Receptivity | SpringerLink

Trophoblast Invasion and Endometrial Receptivity. Novel Aspects of the Cell Biology of Embryo Implantation. ... Adhesive Interactions of Murine and Human Trophoblast Cells Susan J. Fisher, Ann Sutherland, Lenny Moss, Lynn Hartman, Eileen ... Cell Biology and Immunology of the Invasive Trophoblast. * Front Matter Pages 113-113 ... The Role of Matrix Macromolecules in the Invasion of Decidua by Trophoblast: Model Studies Using BeWo Cells ...
more infohttps://link.springer.com/book/10.1007%2F978-1-4613-0615-3

Placenta and Trophoblast: Methods and Protocols - Google BooksPlacenta and Trophoblast: Methods and Protocols - Google Books

Highlights include strategies for the isolation and culture of trophoblast cells from primates, ruminants, and rodents, and ... Volume 1 provides readily reproducible protocols for studying embryo-uterine implantation, trophoblast cell development, and ... and molecular strategies for assessing trophoblast/placental growth, differentiation and function. ... A collection of cutting-edge laboratory techniques for the study of trophoblast and placental biology. The techniques presented ...
more infohttps://books.google.com/books/about/Placenta_and_Trophoblast.html?id=kFnqq1XokpAC&hl=en

Human placental trophoblasts confer viral resistance to recipient cells | PNASHuman placental trophoblasts confer viral resistance to recipient cells | PNAS

Placental trophoblasts confer viral resistance. Elizabeth Delorme-Axford, Rogier B. Donker, Jean-Francois Mouillet, Tianjiao ... Placental trophoblasts confer viral resistance. Elizabeth Delorme-Axford, Rogier B. Donker, Jean-Francois Mouillet, Tianjiao ... Human placental trophoblasts confer viral resistance to recipient cells Message Subject (Your Name) has sent you a message from ... 2012) The expression profile of C19MC microRNAs in primary human trophoblast cells and exosomes. Mol Hum Reprod 18(8):417-424, ...
more infohttp://www.pnas.org/content/110/29/12048.full

Hypoxia alters the epigenetic profile in cultured human placental trophoblasts.  - PubMed - NCBIHypoxia alters the epigenetic profile in cultured human placental trophoblasts. - PubMed - NCBI

Hypoxia alters the epigenetic profile in cultured human placental trophoblasts.. Yuen RK1, Chen B, Blair JD, Robinson WP, ... Figure 1. Cell culture condition for placental trophoblast samples. Cell cultures were plated and maintained in a culture ... We hypothesized that oxygen tension affects villous trophoblast by modulation of gene expression through DNA methylation. We ... a condition displaying altered development of placental trophoblast. ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/23314690

Utilization of Trophoblast for Early Prenatal Diagnosis | SpringerLinkUtilization of Trophoblast for Early Prenatal Diagnosis | SpringerLink

Davis, M. E., 1959, Trophoblast in the circulating blood during pregnancy, Am. J. Obstet. Gynecol. 78:970.Google Scholar ... Raafat, M., Brayton, J. B., Apgar, V., et al., 1975, A new approach to prenatal diagnosis using trophoblast cells in the ... Rhine S.A., Milunsky A. (1979) Utilization of Trophoblast for Early Prenatal Diagnosis. In: Milunsky A. (eds) Genetic Disorders ...
more infohttps://link.springer.com/chapter/10.1007/978-1-4684-3438-5_13

TPBG (trophoblast glycoprotein)TPBG (trophoblast glycoprotein)

... trophoblast glycoprotein), Authors: Swetha Yadav, Robert J Amato, Virginia Mohlere. Published in: Atlas Genet Cytogenet Oncol ... TPBG (trophoblast glycoprotein). Written. 2013-11. Swetha Yadav, Robert J Amato, Virginia Mohlere. ... TPBG is expressed by all types of trophoblasts by as early as 9 weeks of development. The gene is specific for trophoblastic ... Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine- ...
more infohttp://atlasgeneticsoncology.org/Genes/GC_TPBG.html

Interleukin-1 Modulation of Human Placental Trophoblast ProliferationInterleukin-1 Modulation of Human Placental Trophoblast Proliferation

... stimulates trophoblast proliferation and is upregulated in trophoblast by IL-1," Journal of the Society for Gynecologic ... dependent trophoblast proliferation," Journal of the Society for Gynecologic Investigation, vol. 8, no. 1 suppl, p. 82A, 2001. ... A Nilkaeo, K L Green, and S W Kauma, "Maternal regulation of trophoblast proliferation by decidual interleukin-1 (IL-1)," ... A Nilkaeo, K Green, and S Kauma, "Interleukin-1 (IL-1) stimulation of trophoblast proliferation is mediated by the induction of ...
more infohttps://www.hindawi.com/journals/mi/2006/079359/ref/

Epithelial-mesenchymal transition during trophoblast differentiation.Epithelial-mesenchymal transition during trophoblast differentiation.

In the course of placentation three main trophoblast populations can be identified ... Embryo implantation in higher primates is mediated by trophoblast: in the earliest phases by syncytiotrophoblast, then by both ... Embryo implantation in higher primates is mediated by trophoblast: in the earliest phases by syncytiotrophoblast, then by both ... In the course of placentation three main trophoblast populations can be identified: cytotrophoblast stem cells and two ...
more infohttp://www.biomedsearch.com/nih/Epithelial-mesenchymal-transition-during-trophoblast/9124037.html

Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication.  - PubMed - NCBIPrimary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. - PubMed - NCBI

Cultured primary trophoblasts exhibit AXL, DC-SIGN, TYRO3 and TIM-1, but not L-SIGN transcription as assessed by RT-PCR ... Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication.. Aagaard KM1,2,3,4, Lahon A5, Suter MA1 ... Both mock-infected trophoblasts and those infected with UV-inactivated 1 × 105 ZIKV (left two panels) failed to demonstrate ... On day 5 (donor 1) or day 4 (donor 2) after isolation, now differentiated trophoblasts were infected with ZIKV FLR. (B) Zika ...
more infohttps://www.ncbi.nlm.nih.gov/pubmed/28128342

PA-16-445: Trophoblast Differentiation and Function (R01)PA-16-445: Trophoblast Differentiation and Function (R01)

The placenta is primarily composed of trophoblast cells. The trophoblast cells of the placenta arise from the trophectoderm of ... Research on human trophoblasts is ideal; experimental animal studies are acceptable to enhance our understanding of human ... Developing trophoblast and uterine tissue in vitro co-culture systems to understand stage- and locus-specific interactions ... At the same time these invading trophoblast cells differentiate and gain various functions to form the placenta as well as to ...
more infohttps://grants.nih.gov/grants/guide/pa-files/PA-16-445.html

Trophoblast - WikipediaTrophoblast - Wikipedia

This layer of trophoblasts is also collectively referred to as "the trophoblast", or, after gastrulation, the trophectoderm, as ... The invasion of a specific type of trophoblast (extravillous trophoblast) into the maternal uterus is a vital stage in the ... cytotrophoblast in the tips of villi can differentiate into another type of trophoblast called the extravillous trophoblast. ... Failure of the trophoblast to invade sufficiently is important in the development of some cases of pre-eclampsia. Too firm an ...
more infohttps://en.wikipedia.org/wiki/Trophoblast

Knockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling PathwayKnockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling Pathway

... degradation-related proteins are expressed by extravillous trophoblasts (EVTs) to ensure normal trophoblast invasion [5]. The ... Figure 1: Effect of HPSE on trophoblast cell invasion. 5 × 104 cells were suspended in 100 μl of FBS-free RPMI-1640 medium and ... Figure 2: Effect of HPSE on trophoblast cell tube formation. 1 × 104 cells were seeded on μ-slide angiogenesis plates, coated ... thought that trophoblast-derived heparanase was not required for invasion [16]. The cell lines they used were human first- ...
more infohttps://www.hindawi.com/journals/dm/2018/7413027/

Intermediate trophoblast - WikipediaIntermediate trophoblast - Wikipedia

... differentiated from villous intermediate trophoblast The function of the implantation site intermediate trophoblast is to ... differentiated from villous intermediate trophoblast Chorionic-type intermediate trophoblast at chorionic laeve of fetal ... Intermediate trophoblast is a distinct subtype of trophoblastic tissue that arises from the cytotrophoblast. It is sub- ... Intermediate trophoblasts are thought to be the cell of origin for: Exaggerated placental site (EPS): implantation site IT ...
more infohttps://en.wikipedia.org/wiki/Intermediate_trophoblast

JCI -
Preeclampsia: a link between trophoblast dysregulation and an antiangiogenic stateJCI - Preeclampsia: a link between trophoblast dysregulation and an antiangiogenic state

report for the first time upregulation of SEMA3B by trophoblast cells of patients with preeclampsia (37). This gene encodes ... In preeclampsia, trophoblast invasion is shallow and there is failure of physiologic transformation of the spiral arteries, ... Preeclampsia: a link between trophoblast dysregulation and an antiangiogenic state. Roberto Romero, MD, DMedSci1 and Tinnakorn ... The evidence in support of this includes: (a) SEMA3B mRNA and protein are overexpressed in trophoblasts from patients with ...
more infohttps://www.jci.org/articles/view/70431

Immunobiology of Human Trophoblast | Springer for Research & DevelopmentImmunobiology of Human Trophoblast | Springer for Research & Development

Human Chorionic Gonadotropin Trophoblast Cell Chorionic Villus Extravillous Trophoblast Human Trophoblast These keywords were ... Hsi B-L: Immunobiology of human trophoblast membrane antigens, in Loke YW, Whyte A (eds): Biology of Trophoblast, Amsterdam, ... Contractor SF: Metabolic and enzymatic activity of human trophoblast, Loke YW, Whyte A (eds): Biology of Trophoblast. Amsterdam ... Kurman RJ, Main CS, Chen H-C: Intermediate trophoblast: a distinctive form of trophoblast with specific morphological, ...
more infohttps://rd.springer.com/chapter/10.1007/978-1-4612-3746-4_12

ABCA1 affects placental function via trophoblast and macrophageABCA1 affects placental function via trophoblast and macrophage

ABCA1 was mainly located on trophoblast membranes. Decreased ABCA1 expression in trophoblasts reduced the cholesterol efflux of ... trophoblasts (P < 0.01). while increased ABCA1 expression in trophoblasts reduced the cholesterol efflux of trophoblasts (P < ... Trophoblasts and macrophages were isolated from the placenta with enzymatic digestion; Immunofluorescence assay was used to ... The cholesterol efflux assays of primary trophoblasts was detected by Amplex Red cholesterol assay kit (Invitrogen); ...
more infohttps://insights.ovid.com/pubmed?PMID=29066252

Trophoblast cell financial definition of trophoblast cellTrophoblast cell financial definition of trophoblast cell

What is trophoblast cell? Meaning of trophoblast cell as a finance term. What does trophoblast cell mean in finance? ... Definition of trophoblast cell in the Financial Dictionary - by Free online English dictionary and encyclopedia. ... Trophoblast cell financial definition of trophoblast cell https://financial-dictionary.thefreedictionary.com/trophoblast+cell ... redirected from trophoblast cell). Also found in: Dictionary, Thesaurus, Medical, Legal, Encyclopedia. cell. an independent ...
more infohttp://financial-dictionary.thefreedictionary.com/trophoblast+cell

Trophoblast Stem Cell Markers Research Area: R&D SystemsTrophoblast Stem Cell Markers Research Area: R&D Systems

Find Trophoblast Stem Cell Markers research area related information and Trophoblast Stem Cell Markers research products from R ... In addition, the trophectoderm develops into the trophoblast cell layers of the placenta. Metastasizing trophoblast cells are ... Trophoblast Stem Cell Markers. Human embryonic stem cells differentiate to form the three germ layers (ectoderm, mesoderm, and ... Thus, trophoblast stem cells are used to model trophoectoderm differentiation and placental development in vitro. Research ...
more infohttps://www.rndsystems.com/research-area/trophoblast-stem-cell-markers

A Grhl2-dependent gene network controls trophoblast branching morphogenesis | DevelopmentA Grhl2-dependent gene network controls trophoblast branching morphogenesis | Development

S3B). Consistently, trophoblast branching was initiated in mutants, indicating that the disturbed trophoblast branching was not ... 2003). SOCS3: an essential regulator of LIF receptor signaling in trophoblast giant cell differentiation. EMBO J. 22, 372-384. ... Grhl2−/− placentas show defective trophoblast branching and BCT abnormalities. (A-F) H&E staining of Grhl2+/− control and Grhl2 ... Labeling with the trophoblast marker TCFAP2C confirmed the ordered appearance of BCT cells in wild-type placentas, but revealed ...
more infohttp://dev.biologists.org/content/142/6/1125