High resolution copy number analysis of IRF4 translocation-positive diffuse large B-cell and follicular lymphomas - Zurich...
Overall this study unravels a recurrent pattern of secondary genetic alterations in IRF4 translocation-positive lymphomas. ... Overall this study unravels a recurrent pattern of secondary genetic alterations in IRF4 translocation-positive lymphomas. ... Translocations affecting chromosome subband 6p25.3 containing the IRF4 gene have been recently described as characteristic ... Translocations affecting chromosome subband 6p25.3 containing the IRF4 gene have been recently described as characteristic ...http://www.zora.uzh.ch/id/eprint/76318/
NIOSHTIC-2 Publications Search - 20034078 - International study of factors affecting human chromosome translocations.
Further, the shape of the relationship between age and translocation frequency (TF) has not been definitively determined. We ... and cigarette smoking on background translocation yields have not been examined systematically. ... Chromosome translocations in peripheral blood lymphocytes of normal, healthy humans increase with age, but the effects of ... Genetic-factors; Racial-factors; Smoking ... the shape of the relationship between age and translocation ...https://www.cdc.gov/niosh/nioshtic-2/20034078.html
Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders:...
Selective Chromatid Segregation Mechanism Explains the Etiology of Chromosome 11 Translocation-Associated Psychotic Disorders: ... 11 translocations associated with psychosis found in three families provide the only convincing evidence for the genetic ... The translocations we propose might cause random segregation of its sister chromatids to explain the result of 50% penetrance. ... The paradoxes we try to resolve here concern the fact that the translocation breakpoints for chromosome 11 lie far apart, ...https://www.omicsonline.org/peer-reviewed/selective-chromatid-segregation-mechanism-explains-the-etiology-of-chromosome-11-translocationassociated-psychotic-disorders-a-rev-28534.html
WikiGenes - Translocation, Genetic
Associations of Translocation, Genetic with chemical compounds. *CML cells carrying the t(9;22) chromosomal translocation are ... Gene context of Translocation, Genetic. *A t(9;12)(p24;p13) chromosomal translocation in a T cell childhood acute lymphoblastic ... Disease relevance of Translocation, Genetic. *Acute lymphoblastic leukemias carrying a chromosomal translocation involving the ... Anatomical context of Translocation, Genetic. *DNA containing breakpoints of two different t(7;9) chromosomal translocations ...https://www.wikigenes.org/e/mesh/e/23250.html
Familial Turner syndrome with an X;Y translocation mosaicism: implications for genetic counseling.
We report an unusual case of familial Turner syndrome with mosaicism for a novel X;Y translocation involving Xp ... We report an unusual case of familial Turner syndrome with mosaicism for a novel X;Y translocation involving Xp and Yp. The ... Prenatal diagnosis revealed a female karyotype, with transmission of the maternal translocation with an unexpected different ...http://www.biomedsearch.com/nih/Familial-Turner-syndrome-with-translocation/22809487.html
Translocations: the genetic rescue paradox | ConservationBytes.com
Translocations: the genetic rescue paradox. 14 01 2013 Harvesting and habitat alteration reduce many populations to just a few ... translocations might elicit outbreeding depression, regardless of whether inbreeding depression is counteracted.Translocations ... Such passive genetic manipulations have become a major tool in conservation biology and they are likely to become more and more ... In translocations, the opposite of outbreeding depression is 'hybrid vigour' (also known as 'heterosis'), that is, when foreign ...https://conservationbytes.com/2013/01/14/translocations-genetic-rescue-paradox/?like=1&source=post_flair&_wpnonce=420e8d64d7
Translocations and the 'genetic rescue' of bottlenecked populations
... it is essential to realise that genetic interventions in form of reciprocal translocations need to be complemented with other ... To confirm whether 'genetic rescue' through the use of inbred populations can be used in a free-living animal, I repeated the ... The objective of this thesis was to examine both the consequences of severe bottlenecks and the use of translocations to ... Severe bottlenecks are expected to lead to increased inbreeding depression and the loss of genetic diversity, and hence reduce ...https://ir.canterbury.ac.nz/handle/10092/7278
"Quantitative genetic and translocation experiments reveal genotype-by-" by M. L. Evans, B. D. Neff et al.
Fry growth also showed strong additive genetic effects. Translocations between populations revealed that offspring survival and ... In one population, we found that additive genetic, nonadditive genetic and maternal effects explained 25%, 34% and 55% of the ... In contrast, fry survival was regulated primarily by additive genetic effects, which indicates a shift from maternal to genetic ... These results indicate genetic differences among individuals in their degree of plasticity and consequently their ability to ...https://scholar.uwindsor.ca/glierpub/60/
Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations | Blood...
The genetic hallmark of FL is the chromosomal translocation t(14;18)(q32;q21) that leads to deregulated expression of the ... Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. Ellen ... Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations. Blood, ... Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations ...http://www.bloodjournal.org/content/114/4/826?ijkey=ea09d74d9de3adf2caaa24272354879800bf5cfa&keytype2=tf_ipsecsha&sso-checked=true
The genetic stability of a recombinant form of the Lr19 translocation of wheat
... Vermaak, Charmaine (1999) ... Genetic susceptibility to tuberculosis in Africans: A genome-wide scan Bellamy R.; Beyers N.; McAdam K.P.W.J.; Ruwende C.; ... The genetic structure of Pyrenophora teres, the causal agent of net blotch of barley, was examined in two fields 30 km apart in ... Population genetic structure and demographical history of South African abalone, Haliotis midae, in a conservation context ...http://scholar.sun.ac.za/handle/10019.1/51482
Trans location t(2;7)(p11.2;q21.2) : a rare genetic aberration associated with B-cell lymphoproliferative disorders of marginal...
Trans location t(2;7)(p11.2;q21.2): a rare genetic aberration associated with B-cell lymphoproliferative disorders of marginal- ...http://uu.diva-portal.org/smash/record.jsf?pid=diva2:760238
Haematology Flashcards by | Brainscape
2 genetic translocations ALL 12;21 (most common), 9:22 (philadelphia) 13 ...https://www.brainscape.com/flashcards/haematology-6627957/packs/10519886
Study Comparing Standard Dose and High-dose Imatinib Mesylate in Patients With Chronic Phase Philadelphia Chromosome Positive ...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ...https://clinicaltrials.gov/show/NCT00171899
A Phase II Study of Flumatinib Versus Imatinib to Treat Philadelphia Chromosome Positive Chronic Myelogenous Leukemia - Full...
Translocation, Genetic. Chromosome Aberrations. Pathologic Processes. Imatinib Mesylate. Antineoplastic Agents. Protein Kinase ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ...https://clinicaltrials.gov/ct2/show/NCT01503502
Genetic and Ecological Consequences of Fish Releases : With Focus on Supportive Breeding of Brown Trout Salmo trutta and...
With Focus on Supportive Breeding of Brown Trout Salmo trutta and Translocation of European Eel Anguilla anguilla. Dannewitz, ... and how does it affect the genetic consequences of a supportive breeding programme? Is there a spatial genetic structure in the ... the present genetic analyses of European eels sampled across the whole distribution range suggest no spatial genetic structure ... 2. Lack of molecular genetic divergence between sea-ranched and wild sea trout (Salmo trutta). Open this publication in new ...http://www.diva-portal.org/smash/record.jsf?pid=diva2:163619
An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening
... mainly including reciprocal translocations and Robertsonian translocations . In the case of reciprocal translocation, at ... Chromosome translocations: segregation modes and strategies for preimplantation genetic diagnosis. Prenat Diagn 1998;18:1437- ... Preimplantation genetic diagnosis. Clin Genet 2009;76:315-325.PMID: 19793305.. 3. Simpson JL. Preimplantation genetic diagnosis ... Fischer J, Colls P, Escudero T, Munné S. Preimplantation genetic diagnosis (PGD) improves pregnancy outcome for translocation ...https://ecerm.org/journal/view.php?number=6
The importance of genetic considerations for planning translocations in the rare healthland species Boronia rivularis (Rutaceae...
The results also indicate that any compensatory translocation program needs to mimic this genetic substructuring. Largely due ... This study revealed genetic diversity was high in some subpopulations but progressively decreased as plant population density ... A previous study of genetic diversity in B. rivularis found a nearby population to be highly inbred and genetically depauperate ... The large population size and the genetic structuring suggest the nearby population may have arisen from this one and ...http://research.usc.edu.au/vital/access/manager/Repository/usc:1464
2012, Graduate Research, Assessing the Need for and Impact of Translocation as a Means of Genetic Rescue in a Declining...
Assessing the Need for and Impact of Translocation as a Means of Genetic Rescue in a Declining Population of Sharp-Tailed ... Assessing the Need for and Impact of Translocation..., 2012. Download whole document (PDF) (774.08 KB) ...https://scholarly.cmich.edu/cgi-bin/cmuscholarly?a=d&d=CMUGR2012-108.1.27
High incidence of t(11;18)(q21;q21) in Helicobacter pylori-negative gastric MALT lymphoma.
Translocation, Genetic*. Treatment Failure. Chemical. Reg. No./Substance: 0/Adaptor Proteins, Signal Transducing; 0/BCL10 ... Translocation-positive gastric MALT lymphomas tend to be aggressive, and patients with such lymphomas might benefit from prompt ... including one case suspicious for a BCL10-involved chromosomal translocation. Our results show that t(11;18)(q21;q21) occurs at ...http://www.biomedsearch.com/nih/High-incidence-in-Helicobacter-pylori/12517817.html
A Cytological Demonstration of the Location of an Interchange Between Two Non-Homologous Chromosomes of Zea Mays (1930)
Translocation, Genetic Relation:. Letter from Barbara McClintock to Charles R. Burnham (December 16, 1929) ...https://profiles.nlm.nih.gov/ps/retrieve/ResourceMetadata/LLBBBW
Burkitt Lymphoma | Encyclopedia.com
In addition to translocations of genetic material, Burkitt's lymphoma is also associated with oncogenic viruses-the Epstein- ... It results from a translocation, or exchange, of genetic material between the long arm of human chromosome 8 and the long arm ... Burkitt's lymphoma is associated with a genetic translocation.. QUESTIONS TO ASK THE DOCTOR. *Should I consider bone marrow ... In addition, patients with Burkitt's lymphoma may want to consider genetic counseling because of the role of the C-myc oncogene ...https://www.encyclopedia.com/medicine/diseases-and-conditions/pathology/burkitt-lymphoma
core binding factor alpha Summary Report | CureHunter
Genetic Translocation (Chromosomal Translocation) 05/01/1995 - "One of the genes that encodes a CBF alpha subunit is AML1, also ... 02/01/1999 - "Both genes involved, translocation ets like gene (or ETV6) on chromosome 12 and acute myeloid leukemia 1 gene (or ... 05/24/2004 - "A common chromosomal translocation in acute myeloid leukemia (AML) involves the AML1 (acute myeloid leukemia 1, ... 05/24/2004 - "A common chromosomal translocation in acute myeloid leukemia (AML) involves the AML1 (acute myeloid leukemia 1, ...http://www.curehunter.com/public/keywordSummaryC406688-core-binding-factor-alpha.do
Symptoms and causes - Mayo Clinic
Being carriers of the genetic translocation for Down syndrome. Both men and women can pass the genetic translocation for Down ... When balanced translocations are inherited, the mother or father has some rearranged genetic material from chromosome 21 on ... A genetic counselor can help you understand your chances of having a child with Down syndrome. He or she can also explain the ... Translocation Down syndrome can be passed from parent to child. However, only about 3 to 4 percent of children with Down ...https://www.mayoclinic.org/diseases-conditions/down-syndrome/symptoms-causes/syc-20355977?footprints=mine&p=1
Clinical experience using single nucleotide polymorphism (SNP) arrays for preimplantation genetic diagnosis (PGD) of...
... of chromosomal translocations ... arrays for preimplantation genetic diagnosis (PGD) of ... Clinical experience using single nucleotide polymorphism (SNP) arrays for preimplantation genetic diagnosis (PGD) ...https://www.wrh.ox.ac.uk/publications/568016
Unbalanced whole-arm translocation der(1;10)(q10-q11;p10-p12) Zamecnikova, Adriana; Al Bahar, Soad (ARMGHM - Atlas Génétique ... Unbalanced whole-arm translocation der(1;13) in hematologic malignancies Zamecnikova, Adriana; Al Bahar, Soad (Jean-Loup ... Translocation, Genetic (5) Adult (5). Humans (5) Leukaemia Section (5) Chromosomes, Human, Pair 1/*genetics (4) ... The derivatives of these translocations have been shown to give rise to a dicentric chromosome in a few cases (Sawyer et al., ...http://documents.irevues.inist.fr/handle/2042/15655/discover?rpp=10&filtertype_0=author&filtertype_1=dateIssued&filter_0=Al+Bahar%2C+Soad&filter_relational_operator_1=equals&filter_1=%5B2010+TO+2017%5D&filter_relational_operator_0=equals&filtertype=subject&filter_relational_operator=equals&filter=Adult