... Goto Sponge NotDistinct Permalink An Entity of Type : yago: ... Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ... Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ... Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ...
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.. Medina DL1, Fraldi A, Bouche V, Annunziata F, ... TFEB Elevates Intracellular Ca2+ Levels through the Activation of MCOLN1. (A) Flow cytometric Ca2+ flux assay of stable TFEB- ... levels through the activation of the lysosomal Ca²⁺ channel MCOLN1. Induction of lysosomal exocytosis by TFEB overexpression ...
The recruitment model for gene activation stipulates that an activator works by bringing the transcriptional machinery to the ... Transcriptional activation by recruitment Nature. 1997 Apr 10;386(6625):569-77. doi: 10.1038/386569a0. ... The recruitment model for gene activation stipulates that an activator works by bringing the transcriptional machinery to the ...
Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Yu Jia, Rong-Gang Xu, Xingjie Ren, Ben Ewen- ... Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Yu Jia, Rong-Gang Xu, Xingjie Ren, Ben Ewen- ... A) Transcriptional activation of hh or ci in the wing (using MS1096-Gal4) results in patterning defects in the anterior and ... 2017) Robust transcriptional activation in plants using multiplexed CRISPR-Act2.0 and mTALE-act systems. Mol Plant 11:245-256. ...
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.. Konermann S1, Brigham MD1, Trevino AE1, Joung J2 ... targeting rules for effective transcriptional activation, to demonstrate multiplexed activation of ten genes simultaneously, ... a, Activation of individual genes by single sgRNAs with dCas9-VP64 and MS2-p65-HSF1. b, Simultaneous activation of the same ten ... Activation levels for each type of MS2-fusion is presented as a percentage relative to the activation achieved using MS2-p65. b ...
In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... providing the first demonstration of dCas9 activation in a multicellular animal. Transcriptional activation using dCas9-VPR ...
Genkwanin up-regulates the transcriptional activation of human type vii collagen gene promoter ... the promoter activity under the presence of flavonoids and we found that Genkwanin up-regulates the transcriptional activation ...
Forming a complex, AR converged with CSL/RBP-Jκ in transcriptional repression of key CAF effector genes. AR and CSL were ... activation. Surprisingly little is known about the role of androgen receptor (AR) signaling in this context. We have found ... from multiple individuals induced early steps of CAF activation, and in an orthotopic skin cancer model, AR loss in HDFs ...
The C-terminal tyrosine-rich region is dispensable for transcriptional activation; rather it renders activation dependent upon ... Genetic evidence for transcriptional activation by the yeast IME1 gene product.. H E Smith, S E Driscoll, R A Sia, H E Yuan and ... Genetic evidence for transcriptional activation by the yeast IME1 gene product.. H E Smith, S E Driscoll, R A Sia, H E Yuan and ... Genetic evidence for transcriptional activation by the yeast IME1 gene product.. H E Smith, S E Driscoll, R A Sia, H E Yuan and ...
... sufficient for transcriptional activation and that an unknown biochemical activity is required for transcriptional activation ( ... Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex. Gwang Sik Kim and ... Y. C. Lee, S. Min, B. S. Gim, and Y. J. Kim, "A transcriptional mediator protein that is required for activation of many RNA ... Y. J. Kim, S. Björklund, Y. Li, M. H. Sayre, and R. D. Kornberg, "A multiprotein mediator of transcriptional activation and its ...
"Transcriptional Activation" by people in Harvard Catalyst Profiles by year, and whether "Transcriptional Activation" was a ... "Transcriptional Activation" is a descriptor in the National Library of Medicines controlled vocabulary thesaurus, MeSH ( ... Below are the most recent publications written about "Transcriptional Activation" by people in Profiles. ... Below are MeSH descriptors whose meaning is more general than "Transcriptional Activation". ...
Transcriptional upregulation of p21Cip1 by ErbB2 overexpression through STAT3 activation. Valerie S. Hawthorne ... Transcriptional upregulation of p21Cip1 by ErbB2 overexpression through STAT3 activation Message Subject (Your Name) has ... Activation of Src kinase has been suggested in STAT3 activation/phosphorylation. We found that Src kinase is activated in ErbB2 ... To see if Src is responsible for ErbB2-mediated STAT3 activation and p21Cip1 upregulation, we established breast cancer cells ...
Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ... "Transcriptional activation by tetracyclines in mammalian cells". Science. 268 (5218): 1766-1769. doi:10.1126/science.7792603. ... It is also human codon optimized and composed of 3 minimal VP16 activation domains. However, the Tet-On 3G protein has 5 amino ... In the Cre and FRT systems, activation or knockout of the gene is irreversible once recombination is accomplished, whereas, in ...
Here, we dissect the transcriptional regulatory domains of WT1 … ... tumour suppressor protein WT1 contains a transcriptional regulatory domain that can either activate or repress transcription ... Regulation of the Wilms tumour suppressor protein transcriptional activation domain Oncogene. 1999 Nov 11;18(47):6546-54. doi ... Additionally, we find that the WT1 transcriptional activation domain interacts with the general transcription factor TFIIB and ...
Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription ... Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription ... Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription ... Transcriptional activation by Sp1 as directed through TATA or initiator: specific requirement for mammalian transcription ...
Moreover, in reporter gene experiments, the transcription activation is highly dependent upon the number of repeats that are ... Importantly, in vivo EWS-FLI1-bound microsatellites are significantly associated with EWS-FLI1-driven gene activation. Put ... 1994) DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) ... Transcriptional control Is the Subject Area "Transcriptional control" applicable to this article? Yes. No. ...
Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone ... Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone ... Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone ... Transcriptional activation of elephant shark mineralocorticoid receptor by corticosteroids, progesterone, and spironolactone ...
Transcriptional activation correlated with the highest increases in MYC binding at promoters. Repression followed a reciprocal ... Integrative analysis of RNA polymerase II and transcriptional dynamics upon MYC activation.. [Stefano de Pretis, Theresia R ... Here, we present an integrated time-course analysis of transcription and mRNA dynamics following MYC activation in ... Altogether, the relative abundance (henceforth, "share") of MYC at promoters was the strongest predictor of transcriptional ...
... of worms with bacterial and fungal pathogens causes the activation of well-characterized innate immune transcriptional programs ... Here, we show that infection-activated transcriptional responses are, in large part, recapitulated by either physiological or ... Together, our data suggest infection and osmotic adaptation share previously unappreciated transcriptional similarities which ... However, the pathophysiological events that drive such transcriptional responses are not understood. ...
In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ...
Genetic and Physiological Activation of Osmosensitive Gene Expression Mimics Transcriptional Signatures of Pathogen Infection ... Genetic and Physiological Activation of Osmosensitive Gene Expression Mimics Transcriptional Signatures of Pathogen Infection ... of worms with bacterial and fungal pathogens causes the activation of well-characterized innate immune transcriptional programs ... Here, we show that infection-activated transcriptional responses are, in large part, recapitulated by either physiological or ...
Through the study of transcriptional activation in response to interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma), a ... Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins ... Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins ... Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins ...
Retinyl Methyl Ether Down-Regulates Activator Protein 1 Transcriptional Activation in Breast Cancer Cells. Anissa Agadir, Y. ... Retinyl Methyl Ether Down-Regulates Activator Protein 1 Transcriptional Activation in Breast Cancer Cells ... Retinyl Methyl Ether Down-Regulates Activator Protein 1 Transcriptional Activation in Breast Cancer Cells ... Retinyl Methyl Ether Down-Regulates Activator Protein 1 Transcriptional Activation in Breast Cancer Cells ...
5A). If transcriptional interference is the primary mechanism by which long-distance transcriptional activation is prevented, ... Northern and 5′ RACE analysis of long-distance activation.To assay long-distance activation at the transcriptional level and to ... cerevisiae to examine long-distance transcriptional activation in vivo and have used it to demonstrate that activation by Gal4 ... is the distance over which transcriptional activation occurs. In S. cerevisiae, upstream activation sequences (UASs) are ...
TRANSCRIPTIONAL REGULATION. TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins. ... E2F transcriptional activation requires TRRAP and GCN5 cofactors. J. Biol. Chem. 276:32627-32634. ... TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins. Mikhail A. Nikiforov, Sanjay ... TRRAP-Dependent and TRRAP-Independent Transcriptional Activation by Myc Family Oncoproteins. Mikhail A. Nikiforov, Sanjay ...