Loading...
*  Transcriptional activation of lysosomal exocytosis promotes cellular clearance. - PubMed - NCBI
Transcriptional activation of lysosomal exocytosis promotes cellular clearance.. Medina DL1, Fraldi A, Bouche V, Annunziata F, ... TFEB Elevates Intracellular Ca2+ Levels through the Activation of MCOLN1. (A) Flow cytometric Ca2+ flux assay of stable TFEB- ... levels through the activation of the lysosomal Ca²⁺ channel MCOLN1. Induction of lysosomal exocytosis by TFEB overexpression ...
https://www.ncbi.nlm.nih.gov/pubmed/21889421?dopt=Abstract
*  Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM | PNAS
Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Yu Jia, Rong-Gang Xu, Xingjie Ren, Ben Ewen- ... Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM. Yu Jia, Rong-Gang Xu, Xingjie Ren, Ben Ewen- ... A) Transcriptional activation of hh or ci in the wing (using MS1096-Gal4) results in patterning defects in the anterior and ... 2017) Robust transcriptional activation in plants using multiplexed CRISPR-Act2.0 and mTALE-act systems. Mol Plant 11:245-256. ...
https://www.pnas.org/content/115/18/4719
*  In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila | Genetics
In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila. Shuailiang Lin, Ben Ewen-Campen, Xiaochun Ni, Benjamin E. ... providing the first demonstration of dCas9 activation in a multicellular animal. Transcriptional activation using dCas9-VPR ...
http://www.genetics.org/content/201/2/433
*  Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. - PubMed - NCBI
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.. Konermann S1, Brigham MD1, Trevino AE1, Joung J2 ... targeting rules for effective transcriptional activation, to demonstrate multiplexed activation of ten genes simultaneously, ... a, Activation of individual genes by single sgRNAs with dCas9-VP64 and MS2-p65-HSF1. b, Simultaneous activation of the same ten ... Activation levels for each type of MS2-fusion is presented as a percentage relative to the activation achieved using MS2-p65. b ...
https://www.ncbi.nlm.nih.gov/pubmed/25494202?dopt=Abstract
*  Regulation of Transcriptional Activation Domain Function by Ubiquitin | Science
Regulation of Transcriptional Activation Domain Function by Ubiquitin Message Subject. (Your Name) has forwarded a page to you ... Regulation of Transcriptional Activation Domain Function by Ubiquitin. By Simone E. Salghetti, Amy A. Caudy, Joshua G. ... Regulation of Transcriptional Activation Domain Function by Ubiquitin. By Simone E. Salghetti, Amy A. Caudy, Joshua G. ... The ability of transcriptional activation domains (TADs) to signal ubiquitin-mediated proteolysis suggests an involvement of ...
http://science.sciencemag.org/content/293/5535/1651
*  Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex
... sufficient for transcriptional activation and that an unknown biochemical activity is required for transcriptional activation ( ... Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex. Gwang Sik Kim and ... Y. C. Lee, S. Min, B. S. Gim, and Y. J. Kim, "A transcriptional mediator protein that is required for activation of many RNA ... Y. J. Kim, S. Björklund, Y. Li, M. H. Sayre, and R. D. Kornberg, "A multiprotein mediator of transcriptional activation and its ...
https://www.hindawi.com/journals/bri/2018/6406372/
*  The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function
Moreover, in reporter gene experiments, the transcription activation is highly dependent upon the number of repeats that are ... Importantly, in vivo EWS-FLI1-bound microsatellites are significantly associated with EWS-FLI1-driven gene activation. Put ... 1994) DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) ... Transcriptional control Is the Subject Area "Transcriptional control" applicable to this article? Yes. No. ...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004932
*  Tetracycline-controlled transcriptional activation - Wikipedia
Tetracycline-Controlled Transcriptional Activation is a method of inducible gene expression where transcription is reversibly ... "Transcriptional activation by tetracyclines in mammalian cells". Science. 268 (5218): 1766-1769. doi:10.1126/science.7792603. ... It is also human codon optimized and composed of 3 minimal VP16 activation domains. However, the Tet-On 3G protein has 5 amino ... In the Cre and FRT systems, activation or knockout of the gene is irreversible once recombination is accomplished, whereas, in ...
https://en.wikipedia.org/wiki/Tetracycline-controlled_transcriptional_activation
*  In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate | Science
In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ... In vitro transcriptional activation by a metabolic intermediate: activation by Leu3 depends on alpha-isopropylmalate ...
http://science.sciencemag.org/content/258/5085/1143
*  NF-Y and the transcriptional activation of CCAAT promoters. - Semantic Scholar
... their interplay is required for transcriptional activation of a sizeable number of eukaryotic genes. NF-Y consists of three ... presence of multiple Transcriptional Start Sites - were previously reviewed (Dolfini et al., 2009) and will not be considered ... NF-Y and the transcriptional activation of CCAAT promoters.. @article{Dolfini2012NFYAT, title={NF-Y and the transcriptional ... Transcriptional activation of PRMT5 by NF-Y is required for cell growth and negatively regulated by the PKC/c-Fos signaling in ...
https://www.semanticscholar.org/paper/NF-Y-and-the-transcriptional-activation-of-CCAAT-Dolfini-Gatta/1e19b24e88b5f60086d61290a88276bc79b6b8c1
*  Kinetics vs. equilibrium binding: Determining the mechanism of transcriptional activation of Polymerase II
The mechanism of transcriptional activation of Polymerase II (Pol II) can be studied in a unique way by using a model ... equilibrium binding: Determining the mechanism of transcriptional activation of Polymerase II. James, Jennifer ... Activation of Pol II by L148F and L148H showed a 20 fold and 3 fold increase over the wild type. The question to be answered is ... If the in vivo concentration is much higher than the equilibrium binding constant, then the activation binding site should be ...
https://mospace.umsystem.edu/xmlui/handle/10355/1713
*  Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells | Cancer Research
Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells. Wei Jin, William N ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ... Evidence for transcriptional activation of the MDR1 gene by CtBP1 in human multidrug resistant cancer cells ...
http://cancerres.aacrjournals.org/content/66/8_Supplement/141.1
*  Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation. | Journal of Virology
Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation.. S Harada, E Kieff ... We now show that EBNA-LP stimulates EBNA-2 activation of the LMP1 promoter and of the LMP1/LMP2B bidirectional transcriptional ... Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation. ... Epstein-Barr virus nuclear protein LP stimulates EBNA-2 acidic domain-mediated transcriptional activation. ...
https://jvi.asm.org/content/71/9/6611?ijkey=268663346cc2cf0d0f6d38c2dc1ba55f11593bfb&keytype2=tf_ipsecsha
*  "Mechanism of transcriptional activation by Pseudomonas aeruginosa ExsA" by Christopher Anthony Vakulskas
Finally, I characterized the mechanism of transcriptional activation by ExsA. ExsA-dependent promoters contain regions that ... In the work presented here I examine the stoichiometry, ligand-interaction properties, and transcriptional activation mechanism ... Transcriptional activators generally recruit RNAP by contacting the α or σ70 subunits (or both). I have found that ExsA ... ExsA is an AraC-family transcriptional regulator that controls expression of T3SS genes in P. aeruginosa. ExsA binds to DNA at ...
https://ir.uiowa.edu/etd/612/
*  Test No. 455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic...
455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic Agonist- ... 455: The Stably Transfected Human Estrogen Receptor-alpha Transcriptional Activation Assay for Detection of Estrogenic Agonist- ...
https://www.oecd-ilibrary.org/environment/test-no-455-the-stably-transfected-human-estrogen-receptor-alpha-transcriptional-activation-assay-for-detection-of-estrogenic-agonist-activity-of-chemicals_9789264076372-en
*  Progestins induce transcriptional activation of signal transducer and activator of transcription 3 ( | Hotze Health & Wellness...
Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (. By: Hotze Health , Tags ... These results demonstrate that progestins are able to induce Stat3 transcriptional activation, which is in turn an obligatory ... June 2005). Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a ...
https://www.hotzehwc.com/2011/06/progestins-induce-transcriptional-activation-of-si/
*  High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. | IOVS | ARVO...
D.H. Platt, M. Bartoli, T. Lemtalsi, R.B. Caldwell; High glucose increases transcriptional activation of VEGF in bovine retinal ... High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. ... High glucose increases transcriptional activation of VEGF in bovine retinal endothelial cells via peroxynitrite. ... STAT3 activation was monitored by western analysis of tyrosine phosphorylation. Results: High glucose (25mM) stimulation of BRE ...
http://iovs.arvojournals.org/article.aspx?articleid=2406305
*  Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional...
Transcriptional activation of VDR target genes by p53, p63γ, or p73. HCT116 cells were infected with Ad-LacZ, Ad-p53, Ad-p63γ, ... The results suggest that VDR plays a key role in the transcriptional activation of a subset of p53 target genes ( Fig. 7B). We ... VDR enhances the transcriptional activation of TP53 downstream genes. We next examined whether the induction of expression of ... Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic ...
http://cancerres.aacrjournals.org/content/66/9/4574
*  Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation -...
... the induction of the expression of the leptin gene by dexamethasone is at least in part due to a transcriptional activation ... Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation De Vos ... Home , Glucocorticoids induce the expression of the leptin gene through a non-classical mechanism of transcriptional activation ... the induction of the expression of the leptin gene by dexamethasone is at least in part due to a transcriptional activation ...
https://infoscience.epfl.ch/record/135316
*  AID 70334 - In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing...
In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/70334
*  AID 156930 - Inhibition of transcriptional activation of human Peroxisome proliferator activated receptor gamma in CHO-K1 cells...
Inhibition of transcriptional activation of human Peroxisome proliferator activated receptor gamma in CHO-K1 cells;ia means ...
https://pubchem.ncbi.nlm.nih.gov/bioassay/156930
*  Maximal transcriptional activation of piscine soluble Toll-like receptor 5 by the NF-κB subunit p65 and flagellin
... ... To better understand the transcriptional regulation of TLR5S gene in fish, we determined the TLR5S 5′-flanking sequence region ...
https://insights.ovid.com/fshimu/201112000/00013844-201112000-00020
*  KAKEN - Research Projects | Transcriptional activation of the HTLV-I gene in monocytes and macrophages. (KAKENHI-PROJECT...
In the present study, we clarified cell-type sp … More ecific transcriptional activation of the HTLV-I LTR in monocytes. CAT ... Transcriptional activation of the HTLV-I gene in monocytes and macrophages.. Research Project ... We propose cell-type specific transcriptional regulation of the HTLV-I gene in monocytes and T-cells. Less ...
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671089/
*  Dual phosphorylation in response regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon...
... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation. Alok K ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ... regulator protein PrrA is crucial for intracellular survival of mycobacteria consequent upon transcriptional activation ...
http://www.biochemj.org/content/474/24/4119.article-info
*  Transcriptional activation of the CrcZ and CrcY regulatory RNAs by the CbrB response regulator in Pseudomonas putida
Transcriptional activation of the CrcZ and CrcY regulatory RNAs by the CbrB response regulator inPseudomonas putida. ... IHF, a co-activator at many σN-dependent promoters, also binds to the promoter regions and contributes to the activation of the ... CbrB phosphorylation is necessary at physiological activation conditions, but a higher dose of the protein allowsin ... vitrotranscriptional activation in its non-phosphorylated form. We also show there is some production of CrcY coming from an ...
https://insights.ovid.com/molmic/201307010/00005797-201307010-00014