Correlated Crx Target Binding, Histone Acetylation and Photoreceptor Gene Transcription in the Developing Mouse Retina | IOVS ...
... leading to their transcriptional activation. ... followed by the peak of transcriptional initiation of cone and ... Purpose: : Active transcription of the photoreceptor genes requires both "de-repression" and activation mechanisms. "De- ... allowing activators and the transcriptional machinery to access their target genes. We reported previously (2004 ARVO, Abstract ... and to compare these patterns with the timing of transcriptional initiation of these target genes. ...
The Effect of Resection on Satellite Cell Activity in Rabbit Extraocular Muscle | IOVS | ARVO Journals
... increase in satellite cell activation. 24 Single myofibers exposed to stretch and labeled with BrdU showed that this activation ... Transcriptional regulation of IGF-1 expression in skeletal muscle. Am J Physiol. 2003;285:C831-C839. [CrossRef] ... Mechanical stretch induces activation of skeletal muscle satellite cells in vitro. Exp Cell Res. 2001;267:107-114. [CrossRef] [ ... Stretch activation and isoforms of myosin heavy chain and troponin-T of rat skeletal muscle fibers. J Muscle Res Cell Motil. ...
A1120, a Nonretinoid RBP4 Antagonist, Inhibits Formation of Cytotoxic Bisretinoids in the Animal Model of Enhanced Retinal...
A transcriptional co-repressor that interacts with nuclear hormone receptors. Nature . 1995; 377: 454-457. [CrossRef] [PubMed] ... from the reporter plasmid containing Gal4 UAS elements due to constitutative RARα-NcoR interaction that brings VP16 activation ... Transcriptional coregulators of the nuclear receptor superfamily: coactivators and corepressors. Cell Mol Life Sci . 2001; 58: ... First, we developed a TR-FRET assay for agonist-induced RARα interaction with transcriptional co-activator SRC1 using the GST- ...
Role of Caveolin-1 for Blocking the Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy | IOVS | ARVO Journals
ERK activation leads to increased collagen expression in lung fibroblasts.34 Corroborating these studies suggests that ... increased transcriptional activity of β-catenin, and enhanced tumor cell invasion. Cancer Cell. 2003; 4: 499-515. ... previous studies showed that Caveolin-1 was upregulated in EMT via the activation of a focal adhesion kinase.14 Epidermal ... dysregulated Caveolin-1 might fail to block ERK phosphorylation, which results in Smad2/3 activation.39 On the other hand, ...