Plant transcription factor database TcoF-DB: Database of transcription co-factors and transcription factor interactions ... This is also true with transcription factors: Not only do transcription factors control the rates of transcription to regulate ... DNA within nucleosomes is inaccessible to many transcription factors. Some transcription factors, so-called pioneer factors are ... an important class of transcription factors called general transcription factors (GTFs) are necessary for transcription to ...
A new study in Nature Genetics describes how changes in the levels of transcription factors can affect normal-range phenotypic ...
transcription factor 4. Names. SL3-3 enhancer factor 2. class B basic helix-loop-helix protein 19. immunoglobulin transcription ... This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an ... Transcription factor 4 expression and correlation with tumor progression in gallbladder cancer. Title: Transcription factor 4 ... TCF4 transcription factor 4 [Homo sapiens] TCF4 transcription factor 4 [Homo sapiens]. Gene ID:6925 ...
Transcription Factor SP2 Regulates Ski-mediated Astrocyte Proliferation In Vitro. Title: Transcription Factor SP2 Regulates Ski ... SP2 Sp2 transcription factor [Homo sapiens] SP2 Sp2 transcription factor [Homo sapiens]. Gene ID:6668 ... Sp2 transcription factorprovided by HGNC. Primary source. HGNC:HGNC:11207 See related. Ensembl:ENSG00000167182 MIM:601801; ... enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA Inferred from Biological aspect of Ancestor. ...
... Science. 2000 Oct 6;290(5489):134-8. doi: 10.1126/ ... Transcription Factors / chemistry * Transcription Factors / genetics * Transcription Factors / metabolism* * Transcription, ...
... by Michael McCoy January 23, 2022 , A version of this story appeared in ... Transcription factors have long been considered targets for cancer treatments but were considered undruggable using ... 75 million in a deal to develop small-molecule oncology drugs that target transcription factors, proteins that control gene ...
The short length and high degeneracy of sites recognized by DNA-binding transcription factors limit the amount of information ... or both for thirty-eight transcription factors. We show that these signatures allow transcription factors with substantial ... Spatial promoter recognition signatures may enhance transcription factor specificity in yeast PLoS One. 2013;8(1):e53778. doi: ... The short length and high degeneracy of sites recognized by DNA-binding transcription factors limit the amount of information ...
... transcription factor activity, nucleic acid binding transcription factor activity, gene-specific transcription factor, nucleic ... acid binding transcription factor activity, DNA binding transcription factor activity, gene-specific transcription factor ... metal ion regulated sequence-specific DNA binding transcription factor activity, transcription factor activity, metal ion ... sequence-specific DNA binding bacterial-type RNA polymerase transcription factor activity, transcription factor activity, ...
... and other transcription factors (nuclear factor kappa B and sterol regulatory element binding protein). Knowledge of the ... Comba, A., Lin, YH., Eynard, A.R. et al. Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors. ... Tontonoz, P., Kim, J. B., Graves, R. A., & Spiegelman, B. M. (1993). ADD1: a novel helix-loop-helix transcription factor ... Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors. *Andrea Comba1, ...
In this study, we examined activating transcription factor 3 (ATF3), a mediator of the UPR that promotes acinar-to-ductal ... Loss of activating transcription factor 3 prevents KRAS-mediated pancreatic cancer. Oncogene * Nawab Azizi, Childrens Health ... In this study, we examined activating transcription factor 3 (ATF3), a mediator of the UPR that promotes acinar-to-ductal ... Nawab Azizi, Jelena Toma, Mickenzie Martin, Muhammad Faran Khalid, et al.. "Loss of activating transcription factor 3 prevents ...
View mouse Gtf2i Chr5:134266688-134343614 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression
Solution Structure of Transcription Factor Sp1 DNA Binding Domain (Zinc Finger 3) ... NMR structure of transcription factor Sp1 DNA binding domain. Oka, S., Shiraishi, Y., Yoshida, T., Ohkubo, T., Sugiura, Y., ... It is proposed that this relaxed property of finger 1 allows transcription factor Sp1 to bind various DNA sequences with high ... To understand the DNA recognition mechanism of zinc finger motifs of transcription factor Sp1, we have determined the solution ...
Copyright © 2017 REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies ...
IPR001699 T-box transcription factor. IPR046360 T-box transcription factor, DNA-binding domain ...
The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. ... The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells. ... Here we show that the T-box transcription factor Brachyury induces in tumor cells epithelial-mesenchymal transition (EMT), an ... Brachyury overexpression also repressed E-cadherin transcription, an effect partially mediated by Slug. Conversely, inhibition ...
Copyright © 2017 REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies ... sequence-specific DNA binding transcription factor activity. ENSLAFP00000017681. GO:0043565. molecular_function. sequence- ...
Copyright © 2017 REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies ...
Here, we show in utero gain-of-function of the psychiatric risk gene transcription factor 4 (TCF4) severely disrupts the ... Our novel findings indicate that TCF4-dependent transcription directs the proper formation of prefrontal cortical minicolumns ... columnar organization of medial prefrontal cortex (mPFC) in a transcription- and activity-dependent manner. This morphological ...
Pheromone-binding domain of LuxR-like quorum-sensing transcription factors: *Protein Transcription factor TraR, N-terminal ... Pheromone-binding domain of LuxR-like quorum-sensing transcription factors. Timeline for Protein Transcription factor TraR, N- ... Pheromone-binding domain of LuxR-like quorum-sensing transcription factors appears in SCOPe 2.01. *Protein Transcription factor ... Pheromone-binding domain of LuxR-like quorum-sensing transcription factors appears in SCOPe 2.03. *Protein Transcription factor ...
... and is the archetypical transcription factor to study actin interplay with transcription. We show that neuronal motility evoked ... 2002) Mutant actins demonstrate a role for unpolymerized actin in control of transcription by serum response factor. Mol Biol ... A Nuclear Actin Function Regulates Neuronal Motility by Serum Response Factor-Dependent Gene Transcription. Sina Stern, Evaine ... SRF is the archetypical transcription factor for studying actin interplay with gene expression (Posern and Treisman, 2006; ...
When blood vessel growth is disturbed, it can be an important factor in the progression of cancer, diabetes and eye diseases. ... Absence of transcription factor unleashes blood vessel growth. by Max Planck Society ... Citation: Absence of transcription factor unleashes blood vessel growth (2016, January 18) retrieved 3 December 2023 from https ... the transcription factor FOXO1, which controls how genes are read in the cell nucleus. "When we inactivated FOXO1 in mice in ...
The entire BD Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit must be stored in the dark at 2° to 8°C. Do not ... Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H. A novel octamer binding transcription factor is differentially ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ...
Timeline for Superfamily a.90.1: Transcription factor STAT-4 N-domain: *Superfamily a.90.1: Transcription factor STAT-4 N- ... Lineage for Superfamily a.90.1: Transcription factor STAT-4 N-domain. *Root: SCOP 1.55 *. Class a: All alpha proteins [46456] ( ... Superfamily a.90.1: Transcription factor STAT-4 N-domain appears in the current release, SCOPe 2.08. ... Superfamily a.90.1: Transcription factor STAT-4 N-domain [48092] (1 family) ...
NAC transcription factors regulate the stress response in plants. Pumpkin (Cucurbita moschata) is an important cucurbit ... Our results indicated that CmNAC1 is a critical factor in ABA signaling pathways and it can be utilized in transgenic breeding ... Our results indicated that CmNAC1 is a critical factor in ABA signaling pathways and it can be utilized in transgenic breeding ... Transactivation assay in yeast cells revealed that CmNAC1 functions as a transcription activator, and its transactivation ...
The transcription factor MntR is a metallosensor that regulates Mn2+ ion homeostasis in the bacterium Bacillus subtilis. Its ... which consists of Fe2+-sensing transcription factors such as DtxR and IdeR, and of Mn2+-sensing transcription factors such as ... Structural Dynamics of the Bacillus subtilis MntR Transcription Factor Is Locked by Mn2+ Binding by Zoe Jelić Matošević ... The transcription factor MntR is a metallosensor that regulates Mn2+ ion homeostasis in the bacterium Bacillus subtilis. Its ...
Transcription Factor B Contacts Promoter DNA Near the Transcription Start Site of the Archaeal Transcription Initiation Complex ... 59 BASIC BIOLOGICAL SCIENCES; transcription initiation; initial transcription; promoter escape; sigma factor; initiation factor ... Displacement of the transcription factor B reader domain during transcription initiation journal, August 2018 * Dexl, Stefan; ... Extracytoplasmic (ECF) σ factors, the largest class of alternative σ factors, are related to primary σ factors, but have ...
Tom Kerppola on Visualization of transcription factor interactions in living cells, part of a collection of multimedia lectures ... Visualization of transcription factor interactions in living cells. *Prof. Tom Kerppola - University of Michigan, USA ... Other Talks in the Series: Epigenetics, Chromatin, Transcription and Cancer. The basal transcription machinery for RNA ... Visualization of transcription factor interactions in living cells. Embed in course/own notes ...
Novel homozygous mutations in the transcription factor NRL cause non-syndromic retinitis pigmentosa Mohammed E. El-Asrag,1,2 ... Rehemtulla A, Warwar R, Kumar R, Ji X, Zack DJ, Swaroop A. The basic motif-leucine zipper transcription factor Nrl can ... other transcription factors to regulate the activity of photoreceptor-specific genes such as rhodopsin [9-11]. The transgenic ... in the transcription factor gene NRL-was identified as the best candidate. AgileMultiIdeogram analysis of the WES data ...
Transcription factors have crucial roles in stem cell biology and differentiation. Research in these fields has broad ... Transcription factors are proteins that regulate the transcription of genes, or the production of mRNA from DNA. Their unique ... Once the transcription factor binds to an enhancer region, this can cause stimulation or repression of gene transcription. ... and together with co-factors such as Nuclear Factor Kappa (NF-κB) and hypoxia-inducible factor 1 alpha (HIF-1α), can induce ...
... a stress-inducible transcription factor, is rapidly upregulated under various stress conditions and plays an important role in ... phosphorylated eukaryotic initiation factor 2,i,α,/i, (eIF2,i,α,/i,), phosphorylated protein endoplasmic-reticular- ... Activating transcription factor-(ATF-) 3, a stress-inducible transcription factor, is rapidly upregulated under various stress ... A. E. Pelzer, J. Bektic, P. Haag et al., "The expression of transcription factor activating transcription factor 3 in the human ...