Transcription Factor TFIIA - Semantic Scholar
This complex is composed of transcription initiation factor IIA subunits 1 and 2 and is involved in the stabilization of the ... A protein complex that is required for RNA polymerase II-dependent transcription of DNA. ... Transcription Factor TFIIA. Known as: Transcription Factor IIA, RNA Polymerase II, Transcription Factor A, TFIIA (More). ... The X-ray crystal structure of the transcription factor IIA (TFIIA)in complex with the TATA-box-binding protein (TBP) and TATA ...https://www.semanticscholar.org/topic/Transcription-Factor-TFIIA/261408
Cleavage and proteasome‐mediated degradation of the basal transcription factor TFIIA | The EMBO Journal
The transcription factor TFIIA is encoded by two genes, TFIIAαβ and TFIIAγ. In higher eukaryotes, the TFIIAαβ is translated as ... specific transcription factor ALF in Xenopus oocytes compensates for translational inactivation of the somatic factor TFIIA. J ... The basal transcription factor TFIIA has been shown to enhance transcription by interacting with TBP and stabilising its ... DeJong J, Bernstein R, Roeder RG (1995) Human general transcription factor TFIIA: characterization of a cDNA encoding the small ...http://emboj.embopress.org/content/23/15/3083
gtf2a1 - General transcription factor IIA, 1 - Danio rerio (Zebrafish) - gtf2a1 gene & protein
IPR009083. TFIIA_a-hlx. IPR004855. TFIIA_asu/bsu. IPR009088. TFIIA_b-brl. ... IPR009083. TFIIA_a-hlx. IPR004855. TFIIA_asu/bsu. IPR009088. TFIIA_b-brl. ... General transcription factor IIA, 1Imported. ,p>Information which has been imported from another database using automatic ... tr,Q7ZUK2,Q7ZUK2_DANRE General transcription factor IIA, 1 OS=Danio rerio OX=7955 GN=gtf2a1 PE=2 SV=1 ...http://www.uniprot.org/uniprot/Q7ZUK2
TOA2 | SGD
Subunit of transcription factor TFIIA complex involved in RNA polymerase II transcriptional preinitiation complex assembly. ... for ribosomal protein gene transcription in vivo; homologous to smallest subunit of human and Drosophila TFIIA; protein ... TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; required, along with ...https://www.yeastgenome.org/locus/S000001541
Transcription factor II A - Wikipedia
Transcription factor TFIIA is a nuclear protein involved in the RNA polymerase II-dependent transcription of DNA. TFIIA is one ... Transcription Factor TFIIA at the US National Library of Medicine Medical Subject Headings (MeSH). ... Høiby T, Zhou H, Mitsiou DJ, Stunnenberg HG (2007). "A facelift for the general transcription factor TFIIA". Biochimica et ... transcription. The requirement for TFIIA in vitro transcription systems has been variable, and it can be considered either as a ...https://en.wikipedia.org/wiki/Transcription_factor_II_A
GTF2A2 - Transcription initiation factor IIA subunit 2 - Homo sapiens (Human) - GTF2A2 gene & protein
TFIIA in a complex with TBP mediates transcriptional activity. ... TFIIA is a component of the transcription machinery of RNA ... IPR009083. TFIIA_a-hlx. IPR009088. TFIIA_b-brl. IPR003194. TFIIA_gsu. IPR015871. TFIIA_gsu_C. IPR015872. TFIIA_gsu_N. ... IPR009083. TFIIA_a-hlx. IPR009088. TFIIA_b-brl. IPR003194. TFIIA_gsu. IPR015871. TFIIA_gsu_C. IPR015872. TFIIA_gsu_N. ... transcription factor TFIIA complex Source: BHF-UCL ,p>Inferred from Direct Assay,/p> ,p>Used to indicate a direct assay for the ...http://www.uniprot.org/uniprot/P52657
CC] transcription factor TFIIA complex *[MF] RNA polymerase II repressing transcription factor binding *[MF] TBP-class protein ... positive regulation of sequence-specific DNA binding transcription factor activity *[BP] positive regulation of transcription ... BP] transcription from RNA polymerase II promoter *[BP] transcription initiation from RNA polymerase II promoter *[BP] viral ... BP] transcription elongation from RNA polymerase II promoter *[ ... TFIIA_gamma_N. TFIIA_gamma_C Related Sequences. mRNA. GenPept. ...https://cgap.nci.nih.gov/Genes/GeneInfo?ORG=Hs&CID=512934&LLNO=2958
Transcription | Encyclopedia.com
Transcription Transcription is the process in which genetic information stored in a strand of DNA is copied into a strand of ... TFIIA is transcription factor A, which functions with RNA polymerase II.. RNA Polymerase I and III Transcription. RNA ... which is recognized by a multicomponent transcription factor called TFIID. One of the components of the transcription factor is ... Transcription Genetics Copyright Genetics Society of America. Transcription. Transcription is the process in which genetic ...https://www.encyclopedia.com/science-and-technology/biology-and-genetics/genetics-and-genetic-engineering/transcription
General transcription factors (TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH: 1, 2) • GLI-Krüppel family (1, 2, 3, YY1) • KLF (2, 4 ... Transcription factors and intracellular receptors. (1) Basic domains. (1.1) Basic leucine zipper (bZIP). Activating ... CCAAT-enhancer-binding proteins (or C/EBPs) are a family of transcription factors that are composed of six members C/EBP α to C ... 3.4) Heat Shock Factors. HSF1. (3.5) Tryptophan clusters. ELF (4, 5) • Interferon regulatory factors (1, 2, 3, 4, 5, 6, 7, 8 ...https://www.bionity.com/en/encyclopedia/Ccaat-enhancer-binding_proteins.html
General transcription factors (TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH: 1, 2) • GLI-Krüppel family (1, 2, 3, YY1) • KLF (2, 4 ... Transcription factors and intracellular receptors. (1) Basic domains. (1.1) Basic leucine zipper (bZIP). Activating ... Transcription factors * Steroid hormone receptor: * Sex hormone receptors (sex hormones) * Estrogen receptor (α and β) ... 3.4) Heat Shock Factors. HSF1. (3.5) Tryptophan clusters. ELF (4, 5) • Interferon regulatory factors (1, 2, 3, 4, 5, 6, 7, 8 ...https://www.bionity.com/en/encyclopedia/Intracellular_receptor.html
Specific Defects in Different Transcription Complexes Compensate for the Requirement of the Negative Cofactor 2 Repressor in...
1996), whereas the general transcription factor TFIIA accelerates and stabilizes binding of TBP to TATA boxes (Yokomori et al. ... Previous studies identified mutations in the mediator component SIN4 and in the general transcription factor TFIIA as ... Gileadi, O., W. J. Feaver and R. D. Kornberg, 1992 Cloning of a subunit of yeast RNA polymerase II transcription factor b and ... Transcription initiation is tightly controlled by the interplay between positive and negative factors (Narlikar et al. 2002; O ...http://www.genetics.org/content/176/1/125
The General Transcription Factors IIA, IIB, IIF, and IIE Are Required for RNA Polymerase II Transcription from the Human U1...
Another general transcription factor (GTF), TFIIA, can join the initiation complex at any stage of assembly. Like TFIIB, TFIIA ... A role for TFIIA in U6 transcription?TFIIA has been reported previously to be required for U6 transcription in vitro, as well ... purification and analysis of transcription factor IIA and identification of transcription factor IIJ. Mol. Cell. Biol. 12:413- ... Multiple functional domains of human transcription factor IIB. Distinct interactions with two general transcription factors and ...https://mcb.asm.org/content/19/3/2130?ijkey=86c54d395a78f19063c6cbec2b14b54a2f6bbcea&keytype2=tf_ipsecsha
A canonical promoter organization of the transcription machinery and its regulators in the Saccharomyces genome. - PubMed -...
General transcription factors TFIIA, -B, -D, -E, -F, -H were located near the downstream edge from the NFR. The -1 nucleosome ... Distribution of transcription factor occupancy at selected genes. ChIP-chip on Affymetrix high-density tiling arrays was ... Two factors are location-linked if their positions covary at genes in which they co-occupy. The extent to which two factors ... Pol II enrichment and transcription frequency are shown in blue. The transcription frequency, denoted as mRNA/hr (), for each ...https://www.ncbi.nlm.nih.gov/pubmed/19124666
SMART: Secondary literature for CXC domain
... is a testis-specific counterpart of the large subunit of human general transcription factor TFIIA. Northern analysis shows that ... like factor is encoded by a germ cell-specific gene whose expression is up-regulated with other general transcription factors ... We hypothesize that ZFP393 functions as a germ cell-specific transcription factor that plays important roles in spermatid ... Characterization of Glis2, a novel gene encoding a Gli-related, Kruppel-like transcription factor with transactivation and ...http://smart.embl-heidelberg.de/smart/show_secondary.cgi?domain=CXC
TAZ (V386) Antibody, UniProt ID Q9GZV5 #4883 to Thioredoxin 1 Antibody (Mouse/Rat Preferred), UniProt ID P10599 #2298 from Cell...
... a general transcription factor made up of paired α and β subunits. These general transcription factors include TFIIA, TFIIB, ... Background: Transcription factor EB (TFEB) is a member of the Myc-related, bHLH leucine-zipper family of transcription factors ... Transcription factor E3 (TFE3) is a member of a family of basic helix-loop-helix leucine zipper transcription factors that ... is facilitated by these general transcription factors. These factors also help in selection of the proper transcription start ...https://www.cellsignal.com/1/1/indexe255.html
Association of Transcription Factor IIA with TATA Binding Protein Is Required for Transcriptional Activation of a Subset of...
1994) Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA. J. ... The general transcription factor IIA (TFIIA) interacts with the TATA binding protein (TBP) and promoter DNA to mediate ... 1995) Analysis of the yeast transcription factor TFIIA: distinct functional regions and a polymerase II-specific role in basal ... 1995) Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal ...https://mcb.asm.org/content/18/5/2559
Association of Transcription Factor IIA with TATA Binding Protein Is Required for Transcriptional Activation of a Subset of...
The general transcription factor IIA (TFIIA) interacts with the TATA binding protein (TBP) and promoter DNA to mediate ... Kang J J, Auble D T, Ranish J A, Hahn S. Analysis of the yeast transcription factor TFIIA: distinct functional regions and a ... Imbalzano A N, Zaret K S, Kingston R E. Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the ... DeJong J, Bernstein R, Roeder R G. Human general transcription factor TFIIA: characterization of a cDNA encoding the small ...http://pubmedcentralcanada.ca/pmcc/articles/PMC110636/?lang=en-ca
SCOP: Class: All alpha proteins
Transcription factor IIA (TFIIA), alpha-helical domain  (1) 4 helices; bundle, closed, right-handed twist *Ectatomin ... Transcription factor STAT-4 N-domain  (1) multihelical; can be divided into two subdomains *TerB-like  (1) ... A DNA-binding domain in eukaryotic transcription factors  (1) 4 helices; the long C-terminal helix protrudes from the ... Triger factor/SurA peptide-binding domain-like  (1) multihelical; irregular array of long and short helices *DNA ...http://scop.mrc-lmb.cam.ac.uk/scop/data/scop.b.b.html
A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of...
PQN-51 is the C. elegans homolog of the general transcription factor TFIIA, noted above to be a candidate target of Taspase ( ... 2018 Quantitating transcription factor redundancy: The relative roles of the ELT-2 and ELT-7 GATA factors in the C. elegans ... 2006 Uncleaved TFIIA is a substrate for taspase 1 and active in transcription. Mol. Cell. Biol. 26(7): 2728-2735. doi:10.1128/ ... 2007 The ELT-2 GATA-factor and the global regulation of transcription in the C. elegans intestine. Dev. Biol. 302(2): 627-645. ...http://www.g3journal.org/content/8/5/1425
GTF2E1 - Wikipedia
"Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA ... General transcription factor IIE subunit 1 (GTF2E1), also known as transcription initiation factor IIE subunit alpha (TFIIE- ... Transcription factor II E GRCh38: Ensembl release 89: ENSG00000153767 - Ensembl, May 2017 GRCm38: Ensembl release 89: ... Kim TK, Ebright RH, Reinberg D (May 2000). "Mechanism of ATP-dependent promoter melting by transcription factor IIH". Science. ...https://en.wikipedia.org/wiki/GTF2E1
Histone recognition and nuclear receptor co-activator functions of Drosophila Cara Mitad, a homolog of the N-terminal portion...
Transcription factor TFIIA and herpes simplex virus host cell factor (HCF1) are cleaved during maturation, with both halves ... 1992). DNA binding and heteromerization of the Drosophila transcription factor chorion factor 1/ultraspiracle. Proc. Natl. Acad ... Nuclear receptors (NRs) function as transcription factors that respond to cellular signals to initiate new gene expression ... and the ecdysone-inducible zinc-finger transcription factor Broad-Complex (BR-C; BR - FlyBase) (Brennan et al., 2001). ...https://dev.biologists.org/content/139/11/1997?ijkey=bc405898a09790dfe6172f8f0d2a2eb689353f78&keytype2=tf_ipsecsha
... cleavage of the general transcription factor TFIIA ensures proper coordination of rapid cell proliferation and morphogenesis by ... Krüppel-like factors (KLFs) are zinc finger transcription factors that share homology in three C-terminal zinc finger domains. ... Here, we identified Krüppel-like factor 6 (KLF6), a zinc finger domain transcription factor, as an essential regulator of ... Taspase1-dependent TFIIA cleavage coordinates head morphogenesis by limiting Cdkn2a locus transcription. ...https://www.jci.org/125/3
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. - PubMed - NCBI
d , Pre-initiation complex (PIC) assembly, entailing the various general transcription factors (TFIIA, TFIIB, TFIID, TFIIE, ... Transcription factors selected for discussion in the main text and their target subunits in Mediator are also indicated. The ... Importantly, a scaffold containing a vestigial subset of general transcription factors and Mediator remains at the promoter to ... These factors recruit a series of chromatin co-activators that can covalently modify nucleosomes at specific histone residues ( ...https://www.ncbi.nlm.nih.gov/pubmed/20940737?dopt=Abstract
Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear...
1994) Transcription factor (TF) IIB and TFIIA can independently increase the affinity of the TATA-binding protein for DNA. J ... Recent studies have shown that TFIIA and the transcription elongation factor TFIIS are imported into the nucleus by Pdr6p/ ... general transcription factor. Kap. karyopherin. MS. mass spectrometry. NLS. nuclear localization sequence. NPC. nuclear pore ... This complex includes the general transcription factor (GTF) TFIID, which is comprised of TBP with its associated factors, and ...http://jcb.rupress.org/content/145/7/1407.full
TOA1 antibody | acris-antibodies.com
Principal nameTOA1 antibodyAlternative names for TOA1 antibodyTranscription initiation factor IIA large subunit, TFIIA 32 kDa ... Transcription initiation factor IIA large subunit, TFIIA 32 kDa subunit. SwissProt ID. P32773 (Yeast) ...https://www.acris-antibodies.com/target/toa1-antibody.htm