Eya1 is required for lineage-specific differentiation, but not for cell survival in the zebrafish adenohypophysis.
The homeodomain transcription factor Six1 and its modulator, the protein phosphatase Eya1, cooperate to promote cell ... Transcription Factor Pit-1 / biosynthesis, genetics. Transcription Factors / biosynthesis, genetics. Zebrafish / embryology*, ... 0/Transcription Factor Pit-1; 0/Transcription Factors; 0/Zebrafish Proteins; 0/homeobox protein PITX3; 0/lhx3 protein, ... The homeodomain transcription factor Six1 and its modulator, the protein phosphatase Eya1, cooperate to promote cell ...http://www.biomedsearch.com/nih/Eya1-required-lineage-specific-differentiation/16458879.html
POU1F1 | Cancer Genetics Web
The transcription factor Pit-1/Pou1f1 regulates GH and prolactin (PRL) secretion in the pituitary gland. Pit-1 expression and ... Inactivation of transcription factor pit-1 to target tumoral somatolactotroph cells.. Hum Gene Ther. 2012; 23(1):104-14 [PubMed ... In the present study, it is demonstrated that administration of the pituitary transcription factor Pit-1 (originally found in ... Detailed involvement of transcription factors including Pit-1 remains to be further investigated. ...http://www.cancerindex.org/geneweb/POU1F1.htm
The glucocorticoid receptor inhibits the human prolactin gene expression by interference with Pit-1 activity - Nalda Asunción M
Transcription Factor Pit-1 ; Transcription Factors/drug effects/*metabolism/physiology ; Tumor Cells, Cultured. ... We conclude that the activated GR functionally interferes with the pituitary specific factor Pit-1, thereby leading to the ... Immunoprecipitation studies show that either anti-GR or anti-Pit-1 antibodies are able to co-precipitate GR and Pit-1, ... Co-transfection experiments in non-pituitary cell lines, using expression vectors for Pit-1 and different mutants of the human ...http://orbi.ulg.ac.be/handle/2268/31656
Synthesis Art | Fine Art America
Transcription Factor And Ribosomal Rna Laguna Design. $44. Print. Similar Designs More from This Artist ... We've shipped over 1 million items worldwide for our 500,000+ artists. Each purchase comes with a 30-day money-back guarantee. ...https://fineartamerica.com/art/synthesis
8B). This model is homozygous for a mutation in pituitary transcription factor-1 (Pit-1), which plays a key role in the ... Camper SA, Saunders TL, Katz RW, Reeves RH: The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf ... pituitary transcription factor-1; PND, postnatal day; SSC, sodium chloride-sodium citrate. ... Elevated levels of some of these factors, including tumor necrosis factor-α (2), plasminogen-activator inhibitor-1 (3), ...http://diabetes.diabetesjournals.org/content/52/2/268
adenocarcinoma of pituitary gland 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
In the present study, it is demonstrated that administration of the pituitary transcription factor Pit-1 (originally found in ... Chemical-registry-number] 0 / DNA-Binding Proteins; 0 / POU1F1 protein, human; 0 / RNA, Messenger; 0 / Transcription Factor Pit ... Chemical-registry-number] 0 / Receptors, Calcitriol; 0 / Transcription Factor Pit-1; 12629-01-5 / Human Growth Hormone; 1406-16 ... Transcription Factor Pit-1; EC 188.8.131.52 / CREB-Binding Protein; EC 2.7.7.- / RNA Polymerase II ...http://www.bmlsearch.com/?kwr=adenocarcinoma+of+pituitary+gland+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
The costimulatory genes Cd80 and Cd86 are linked on mouse chromosome 16 and human chromosome 3, Mammalian Genome | 10.1007...
Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1 ... Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors ... 1997 The costimulatory genes Cd80 and Cd86 are linked on mouse Chromosome 16 and human Chromosome 3 Roger H. Reeves, 1 David ... Characterization of the murine B7-1 genomic locus reveals an additional exon encoding an alternative cytoplasmic domain and a ...https://www.deepdyve.com/lp/springer_journal/the-costimulatory-genes-cd80-and-cd86-are-linked-on-mouse-chromosome-olJox1SFja
JCI - Volume 120, Issue 12
This role for RB1 was linked to both E2F transcription factor 1-driven upregulation of the androgen receptor (AR) and increased ... Increased expression of Pit-1 has been reported in human tumorigenic breast cells. Here, we found that Pit-1 overexpression or ... Moreover, mitogenic stimuli such as serum, FGF, and HGF increased Enigma transcription via induction of serum response factor ( ... The Pit-1 transcription factor (also know as POU1F1) plays a critical role in cell differentiation during organogenesis of the ...https://www.jci.org/120/12
General Information | Richard Maurer, Ph.D. | OHSU People | OHSU
"The pituitary-specific transcription factor, Pit-1, can direct changes in the chromatin structure of the prolactin promoter." ... "In Vivo mutational analysis of the DNA binding domain of the tissue-specific transcription factor, Pit-1." Journal of ... "Thyrotropin releasing hormone stimulates transient phosphorylation of the tissue-specific transcription factor, Pit-1." Journal ... "Regulation of activating transcription factor-1 and the cAMP response element-binding protein by Ca2+/calmodulin-dependent ...http://www.ohsu.edu/people/richard-maurer/BFD4C89E55524FEFA6F336D4AF82D60C
ZFIN Publication: Angotzi et al., 2011
Transcription Factor Pit-1/chemistry. *Transcription Factor Pit-1/classification. *Transcription Factor Pit-1/genetics ...http://zfin.org/ZDB-PUB-110317-14
Anterior pituitary cells defective in the cell-autonomous factor, df, undergo cell lineage specification but not expansion |...
These cell types are also dependent on the pituitary-specific transcription factor, Pit-1. We present evidence that expression ... Therefore, df and Pit-1 are both cell-autonomous factors required for thyrotrope, somatotrope and lactotrope ontogeny, but ... The presence of all three Pit-1-dependent cell types in clonally derived clusters provides compelling evidence that these three ... Clusters containing different combinations of Pit-1-dependent cell types suggests that the Pit-1+ precursor cells choose from ...http://dev.biologists.org/content/122/1/151
Welcome to LibAge, the ageing reference resource
Entries tagged Transcription Factor Pit-1 (745). Sort:. Number of citations. Author. Title. Year. PubMed ID. ...http://la.ageing-map.org/entries/tags/52/?page=38&s=Transcription%20Factor%20Pit-1&sort=author
Welcome to LibAge, the ageing reference resource
Entries tagged Transcription Factor Pit-1 (745). Sort:. Number of citations. Author. Title. Year. PubMed ID. ... 1992) "Mutation of the POU-specific domain of Pit-1 and hypopituitarism without pituitary hypoplasia." Science 257(5073):1118- ... 2001) "Characterization of aging-associated up-regulation of constitutive nuclear factor-kappa B binding activity." Antioxid. ...http://libage.ageing-map.org/entries/tags/52/
William M. Wood, Ph.D. | Department of Medicine | University of Colorado Denver
Basic science and clinical research advances in the pituitary transcription factors: Pit-1 and Prop-1.. Kerr J, Wood WM, ... Thyroid hormone receptor beta 2 promoter activity in pituitary cells is regulated by Pit-1.. Wood WM, Dowding JM, Bright TM, ... Type 1 and Type 2 Diabetes Mellitus, Lipid Disorders, Obesity. *Thyroid, Pituitary, Adrenal and Parathyroid Disorders and ... specifically sst 5 and 1, in thyrotrope growth arrest by TH and the interface of TRs via sst5 with the cell cycle apparatus. ...http://www.ucdenver.edu/academics/colleges/medicalschool/departments/medicine/EndocrinologyMetabolismDiabetes/faculty_staff/Pages/Wood.aspx
Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern children with growth hormone, prolactin, and...
Transcription Factor Pit-1 ; Transcription Factors/chemistry/*genetics/metabolism ; Transcription, Genetic ; Transcriptional ... is one of the transcription factors responsible for anterior pituitary development and pituitary-specific gene expression. Here ... Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern children with growth hormone, prolactin, and ... Reference : Pro239Ser: a novel recessive mutation of the Pit-1 gene in seven Middle Eastern child.... ...https://orbi.uliege.be/handle/2268/19827
Subnuclear distribution of the largest subunit of the human origin recognition complex during the cell cycle | Journal of Cell...
... selection of specific DNA replication origins must rely on other factors such as chromatin proteins or transcription factors ... Day, R. (1998). Visualization of Pit-1 transcription factor interactions in the living cell nucleus by fluorescence resonance ... In the yeast S. cerevisiae, ORC binding to an ARS element is required for the recruitment of Sir factors and hence for the ... of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2. ...http://jcs.biologists.org/content/117/22/5221
KAKEN - Research Projects | Study on intraocular expression of pituitary hormones possibly involved in the regulation of...
RT-PCR revealed that pituitary-specific transcription factor, Pit-1, was expressed in embryonic chicken neural retinas. The Pit ... Their transcription from the opposite strand of GH starts with downstream of the polyadenylation site of GH-sense mRNAs and ... Two prohormone convertases, PC 1 and PC2, were clone … More d and their specific primers were designed based on the sequences ... Publications] Maria Ling: 'Association of feather colour with constitutively active melanocortin 1 receptors in ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-14540615/
FRET imaging of Pit-1 protein interactions in living cells | (1998) | Periasamy | Publications | Spie
The FRET imaging system was then used to demonstrate dimerization of the pituitary-specific transcription factor Pit-1 within ... FRET imaging of Pit-1 protein interactions in living cells Author(s): Ammasi Periasamy; Richard N. Day ... Date Published: 1 April 1998. PDF: 7 pages. J. Biomed. Opt. 3(2) doi: 10.1117/1.429872. Published in: Journal of Biomedical ...http://spie.org/Publications/Journal/10.1117/1.429872
Pituitary-specific positive transcription factor 1 - Wikipedia
PIT1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH) Transcription Factor Pit-1 at the US ... is a transcription factor for growth hormone. PIT1 is a pituitary-specific transcription factor responsible for pituitary ... Lew AM, Elsholtz HP (1991). "Cloning of the human cDNA for transcription factor Pit-1". Nucleic Acids Res. 19 (22): 6329. doi: ... "Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1". Gene. 122 (2): 387-8. doi:10.1016/ ...https://en.wikipedia.org/wiki/Pituitary-specific_positive_transcription_factor_1
Modulation of fish growth hormone levels by salinity, temperature, pollutants and aquaculture related stress: a review, Reviews...
... activation and repression by pituitary transcription factor Pit-1. Sekkali, B; Brim, H; Muller, M; Argenton, F; Bortolussi, M; ... Cellular distribution of insulin-like growth factor-II (IGF-II) mRNA and hormonal regulation of IGF-I and IGF-II mRNA ... Appearance of insulin-like growth factor mRNA in the liver and pyloric ceca of a teleost in response to erogenous growth ... Effects of growth hormone and insulin-like growth factor 1 on salinity tolerance and gill Na+-K+-ATPase in Atlantic salmon ( ...https://www.deepdyve.com/lp/springer_journal/modulation-of-fish-growth-hormone-levels-by-salinity-temperature-9CKQS34ql0
Corneal Epithelial Wound Healing and Bactericidal Effect of Conditioned Medium From Human Uterine Cervical Stem Cells | IOVS |...
... fibroblast growth factor 6 and 7, urokinase receptor, and hepatocyte growth factor, that could mediate these effects. In vitro ... Ben-Batalla I Seoane S Garcia-Caballero T Deregulation of the Pit-1 transcription factor in human breast cancer cells promotes ... fibroblast growth factors (FGF)-6 and -7, urokinase receptor (uPAR), and hepatocyte growth factor (HGF) were significantly (P ... Thus, factor/s secreted by hUCESCs and not the cells themselves seem to be responsible for wound healing. Our data also seem to ...https://iovs.arvojournals.org/article.aspx?articleid=2212856
JoVE | Peer Reviewed Scientific Video Journal - Methods and Protocols
These results suggest that ER? facilitates Igf1 transcription, whereas ER? appears to inhibit Igf1 gene transcription in mouse ... The mouse Pit-1 w mRNA is generated by using an alternative promoter located in the first intron, as with chicken Pit-1 w, and ... Insulin-like growth factor 1 (IGF-1) is involved in regulations of reproductive functions in rats and mice. IGF-1 expression is ... In the testis, Pit-1 w is expressed as the predominant variant and a protein of 33 kDa. During the first wave of ...https://www.jove.com/visualize?author=Toshiyuki+Kudo
Tso-Pang Yao | Duke School of Medicine
... a potent repressor of the master muscle transcription factor MEF2. ... Alternative translation initiation site usage results in two structurally distinct forms of Pit-1. Pit-1 is a pituitary- ... specific transcription factor that plays a critical role in the normal development of the anterior pituitary gland. ... A stimulus-specific role for CREB-binding protein (CBP) in T cell receptor-activated tumor necrosis factor α gene expression. ...https://medschool.duke.edu/about-us/our-faculty/tso-pang-yao
CiNii 論文 - Expression of Adrenocorticotropic Hormone, Prolactin and Transcriptional Factors...
... aberrant expression of transcription factors NeuroD1 and Pit-1 as a proposed mechanism TAHARA S ... Cell type-specific expression of the pituitary transcription activator pit-1 in the human pituitary and pituitary adenomas ASA ... Differential regulation of proopiomelanocortin and pituitary-restricted transcription factor (TPIT), a new marker of normal and ... Induction of GH, PRL, and TSH beta mRNA by transfection of Pit-1 in a human pituitary adenoma-derived cell line MIYAI S ...https://ci.nii.ac.jp/naid/10021263932
Digital deconvolution FRET microscopy: 3D visualization of protein-protein interactions in a single living cell | (1998) |...
The spatiotemporal dynamics of dimerization of the transcription factor Pit-1 in the living cell nucleus have been visualized ... Cells expressing fluorescent Pit-1 fusion proteins were imaged with a high speed, high sensitivity CCD camera and a water ... The 3-D energy transfer imaging of Pit-1 protein in the nucleus of living cells offers the possibility of studying domains ... These signals were used to create three-dimensional visualization of the distribution of Pit-1 protein dimers. Digitally ...http://spie.org/Publications/Proceedings/Paper/10.1117/12.307087